Sally Mackenzie

Director of the Plant Institute; Huck Chair of Functional Genomics; Professor of Biology and of Plant Science

Sally Mackenzie

Research Summary

Organelle biology and cellular specializations. Plant epigenetics, memory and phenotypic plasticity. Crop epigenetic breeding.

Huck Graduate Students

Huck Affiliations


Publication Tags

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Arabidopsis Phenotype Genes Methylation Breeding Rna Growth Epigenomics Dna Methylation Epigenome Transgenes Mitochondria Dna Epigenetics Proteins Genome Mutation Gene Expression Muts Proteins Dna Binding Proteins Single Nucleotide Polymorphism Memory Chloroplasts Soybeans Plastids

Most Recent Publications

Xuewen Xu, Wei Wang, Yujiao Du, Ziyi Wang, Xueli Liu, Ming Tan, Xiaojian Lin, Jun Xu, Congxi Cai, Xiaohua Qi, Qiang Xu, Aimin Wei, Haipeng Fu, Shengli Du, Sally A. Mackenzie, Yuhui Wang, Xuehao Chen, Xiaodong Yang, 2024, Plant Communications

Kelly Gomez-Campo, Robersy Sanchez, Isabel Martinez-Rugerio, Xiaodong Yang, Tom Maher, C. Cornelia Osborne, Susana Enriquez, Iliana B. Baums, Sally A. Mackenzie, Roberto Iglesias-Prieto, 2024, Molecular Ecology

Robersy Sanchez, Sally A. Mackenzie, 2023, Scientific Reports

Isaac J. Dopp, Kylie Kalac, Sally A. Mackenzie, 2023, Plant Physiology on p. 217-228

Ha Eun Jeh, Robersy Sanchez, Jesús Beltrán, Xiaodong Yang, Hardik Kundariya, Yashitola Wamboldt, Isaac Dopp, Alenka Hafner, Sally A. Mackenzie, 2023, Plant Journal on p. 414-433

Sally A. Mackenzie, Philip M. Mullineaux, 2022, Journal of Experimental Botany on p. 7155-7164

Hardik Kundariya, Robersy Sanchez, Xiaodong Yang, Alenka Hafner, Sally A. Mackenzie, 2022, Genome Biology

F Xu, X Yang, N Zhao, Z Hu, Sally Mackenzie, M Zhang, J Yang, 2022, Horticultural Research

Fengyuan Xu, Xiaodong Yang, Na Zhao, Zhongyuan Hu, Sally A. MacKenzie, Mingfang Zhang, Jinghua Yang, 2022, Horticulture Research

Most-Cited Papers

Jinghua Yang, Dongyuan Liu, Xiaowu Wang, Changmian Ji, Feng Cheng, Baoning Liu, Zhongyuan Hu, Sheng Chen, Deepak Pental, Youhui Ju, Pu Yao, Xuming Li, Kun Xie, Jianhui Zhang, Jianlin Wang, Fan Liu, Weiwei Ma, Jannat Shopan, Hongkun Zheng, Sally A. Mackenzie, Mingfang Zhang, 2016, Nature Genetics on p. 1225-1232

Kamaldeep S. Virdi, John D. Laurie, Ying Zhi Xu, Jiantao Yu, Mon Ray Shao, Robersy Sanchez, Hardik Kundariya, Dong Wang, Jean Jack M. Riethoven, Yashitola Wamboldt, Maria P. Arrieta-Montiel, Vikas Shedge, Sally A. Mackenzie, 2015, Nature Communications on p. 6386

Anna Block, Joshua R. Widhalm, Abdelhak Fatihi, Rebecca E. Cahoon, Yashitola Wamboldt, Christian Elowsky, Sally A. Mackenzie, Edgar B. Cahoon, Clint Chapple, Natalia Dudareva, Gilles J. Basset, 2014, Plant Cell on p. 1938-1948

Sunil K.Kenchanmane Raju, Mon Ray Shao, Robersy Sanchez, Ying Zhi Xu, Ajay Sandhu, George Graef, Sally Mackenzie, 2018, Plant Biotechnology Journal on p. 1836-1847

Xiaodong Yang, Hardik Kundariya, Ying Zhi Xu, Ajay Sandhu, Jiantao Yu, Samuel F. Hutton, Mingfang Zhang, Sally A. Mackenzie, 2015, Plant Physiology on p. 222-232

Kamaldeep S S. Virdi, Yashitola Wamboldt, Hardik Kundariya, John D D. Laurie, Ido Keren, K. R. Sunil Kumar, Anna Block, Gilles Basset, Steve Luebker, Christian Elowsky, Philip M M. Day, Johnna L L. Roose, Terry M M. Bricker, Thomas Elthon, Sally A A. Mackenzie, 2016, Molecular Plant on p. 245-260

Haridik Kundariya, Xiaodong Yang, Kyla Morton, R Sanchez Rodriguez, Robersy Sanchez, Michael J. Axtell, Samuel Hutton, Michael Fromm, Sally A. Mackenzie, 2020, Nature Communications on p. 5345

Xiaodong Yang, Robersy Sanchez, Hardik Kundariya, Tom Maher, Isaac Dopp, Rosemary Schwegel, Kamaldeep Virdi, Michael J. Axtell, Sally A. Mackenzie, 2020, Nature Communications

Roberto De La Rosa Santamaria, Mon Ray Shao, Guomei Wang, David O. Nino-Liu, Hardik Kundariya, Yashitola Wamboldt, Ismail Dweikat, Sally A. Mackenzie, 2014, PLoS One

Natalie Henkhaus, Madelaine Bartlett, David Gang, Rebecca Grumet, Ingrid Jordon-Thaden, Argelia Lorence, Eric Lyons, Samantha Miller, Seth Murray, Andrew Nelson, Chelsea Specht, Brett Tyler, Thomas Wentworth, David Ackerly, David Baltensperger, Philip Benfey, James Birchler, Sreekala Chellamma, Roslyn Crowder, Michael Donoghue, Jose Pablo Dundore-Arias, Jacqueline Fletcher, Valerie Fraser, Kelly Gillespie, Lonnie Guralnick, Elizabeth Haswell, Mitchell Hunter, Shawn Kaeppler, Stefan Kepinski, Fay Wei Li, Sally Mackenzie, Lucinda McDade, Ya Min, Jennifer Nemhauser, Brian Pearson, Peter Petracek, Katie Rogers, Ann Sakai, Delanie Sickler, Crispin Taylor, Laura Wayne, Ole Wendroth, Felipe Zapata, David Stern, 2020, Plant Direct

News Articles Featuring Sally Mackenzie

Lab Bench to Commercialization 2024 grant recipients announced

Four projects led by researchers in the Penn State Eberly College of Science have been selected to receive Lab Bench to Commercialization (LB2C) grants in 2024

New 'Life From All Angles' video features Sally Mackenzie’s epigenetics research

The latest episode of "Life From All Angles," a YouTube series from the Huck Institutes of the Life Sciences, features Penn State Plant Institute Director Sally Mackenzie and her groundbreaking research in the field of epigenetics.

Plant molecular geneticists discover, and begin to crack, the epigenetic code

When plants sense environmental challenges such as drought or extended periods of extreme temperatures, they instinctively reprogram their genetic material to survive and even thrive.

Entrepreneurs compete for better future at Tech Tournament

Illuminate Therapeutics, a game changer in the way head and neck cancers are treated, earned the grand prize cash award of $75,000 at the Invent Penn State Tech Tournament, held April 28-29 at the Penn Stater Hotel & Conference Center, during the 2022 Invent Penn State Venture & IP Conference.

Eberly’s 2022 Lab Bench to Commercialization grant recipients announced

The Eberly College of Science has chosen faculty members Joyce Jose and Sally Mackenzie to receive its 2022 Lab Bench to Commercialization grants. This competitive program provides funding for researchers in the college, enabling them to enhance the commercial potential of ongoing Penn State research and prepare them to translate their Penn State-owned intellectual property to the marketplace.

Epigenetics: Conducting The Symphony Of Genetics

For all the hype, fear and misinformation that surrounds the application of gene editing, there is an equally powerful technology that offers much the same in potential benefit. This technology, epigenetics, is a natural process that has gone largely unremarked by consumers.

High-yielding plants that survive temperature swings may be our next weapon against climate change

Sally Mackenzie spent her childhood summers walking through the vast fields of bright, red, ripe tomato crops: They grow best in the heat of her home state of California. Yet recent seasons prove it can get too hot for a tomato.

Researchers graft tomato plants with epigenetically-modified rootstock

Progeny of novel combination is more vigorous and productive than parental plants. Novel grafted plants — consisting of rootstock epigenetically modified to “believe” it has been under stress — joined to an unmodified scion, or above-ground shoot, give rise to progeny that are more vigorous, productive, and resilient than the parental plants.

Grafting with epigenetically-modified rootstock yields surprise

Novel grafted plants—consisting of rootstock epigenetically modified to “believe” it has been under stress joined to an unmodified scion, or above-ground shoot—give rise to progeny that are more vigorous, productive and resilient than the parent plants.

As climate change makes growing seasons less predictable, scientists dig into a novel approach to boosting crop resilience

Epigenetic modification of plants shows promise for enhancing food security — but we still have a lot to learn.