Rosalyn Irby

Associate Professor of Cancer Research

Rosalyn Irby

Huck Affiliations

Publication Tags

Neoplasms Fluorouracil Prostate Apoptosis Response 4 Protein Colonic Neoplasms Cells Apoptosis Therapeutics Proteins Protein Phosphorylation Apoptosis Regulatory Proteins Isatin Tubulin Modulators Protein Tyrosine Kinases Cetuximab Cell Line Colon Vinblastine Pharmaceutical Preparations Antineoplastic Agent Growth Colorectal Neoplasms Large Granular Lymphocytic Leukemia Pancreatic Neoplasms Resistance

Most Recent Papers

TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells

Jeffrey Q. Nguyen, Rosalyn B. Irby, 2017, Cancer Biology and Therapy on p. 16-25

Intra-cellular tyrosine kinase

Rosalyn Irby, Timothy J. Yeatman, 2015, on p. 231-242

The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer

Joshua E. Allen, Jean Nicolas Gallant, David T. Dicker, Shantu Amin, Rosalyn B. Irby, Arun K. Sharma, Wafik S. El-Deiry, 2013, PLoS One

Par-4 as a potential target for cancer therapy

Rosalyn B. Irby, Christina Lb Kline, 2013, Expert Opinion on Therapeutic Targets on p. 77-87

Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria

Susan Bell Nyland, Daniel J. Krissinger, Michael J. Clemente, Rosalyn B. Irby, Kendall Thomas Baab, Nancy Ruth Jarbadan, Lubomir Sokol, Eric Schaefer, Jason Liao, David Cuthbertson, Pearlie Epling-Burnette, Ronald Paquette, Alan F. List, Jaroslaw P. Maciejewski, Thomas P. Loughran, 2012, Leukemia Research on p. 581-587

The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU

Christina Leah B. Kline, Rosalyn B. Irby, 2011, Apoptosis : an international journal on programmed cell death on p. 1285-1294

Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway

Krishne Gowda, A. S. Prakasha Gowda, Hephzibah Rani S. Tagaram, Kevin F.Staveley O. Carroll, Rosalyn Irby, Arun Sharma, Shantu Amin, 2011, Bioorganic and Medicinal Chemistry on p. 6006-6014

The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model

Arun K. Sharma, Christina L. Kline, Arthur Berg, Shantu Amin, Rosalyn B. Irby, 2011, Clinical Cancer Research on p. 4474-4483

Tyrosine kinase update

Rosalyn B. Irby, Yixing Jiang, 2011, Current Cancer Therapy Reviews on p. 155-166

Voltage-gated Na<sup>+</sup> channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion

Carrie D. House, Charles J. Vaske, Arnold M. Schwartz, Vincent Obias, Bryan Frank, Truong Luu, Narine Sarvazyan, Rosalyn Irby, Robert L. Strausberg, Tim G. Hales, Joshua M. Stuart, Norman H. Lee, 2010, Cancer Research on p. 6957-6967

Most-Cited Papers

Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway

Krishne Gowda, A. S. Prakasha Gowda, Hephzibah Rani S. Tagaram, Kevin F.Staveley O. Carroll, Rosalyn Irby, Arun Sharma, Shantu Amin, 2011, Bioorganic and Medicinal Chemistry on p. 6006-6014

The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model

Arun K. Sharma, Christina L. Kline, Arthur Berg, Shantu Amin, Rosalyn B. Irby, 2011, Clinical Cancer Research on p. 4474-4483

TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells

Jeffrey Q. Nguyen, Rosalyn B. Irby, 2017, Cancer Biology and Therapy on p. 16-25

The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer

Joshua E. Allen, Jean Nicolas Gallant, David T. Dicker, Shantu Amin, Rosalyn B. Irby, Arun K. Sharma, Wafik S. El-Deiry, 2013, PLoS One

Par-4 as a potential target for cancer therapy

Rosalyn B. Irby, Christina Lb Kline, 2013, Expert Opinion on Therapeutic Targets on p. 77-87

Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria

Susan Bell Nyland, Daniel J. Krissinger, Michael J. Clemente, Rosalyn B. Irby, Kendall Thomas Baab, Nancy Ruth Jarbadan, Lubomir Sokol, Eric Schaefer, Jason Liao, David Cuthbertson, Pearlie Epling-Burnette, Ronald Paquette, Alan F. List, Jaroslaw P. Maciejewski, Thomas P. Loughran, 2012, Leukemia Research on p. 581-587

The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU

Christina Leah B. Kline, Rosalyn B. Irby, 2011, Apoptosis : an international journal on programmed cell death on p. 1285-1294

Tyrosine kinase update

Rosalyn B. Irby, Yixing Jiang, 2011, Current Cancer Therapy Reviews on p. 155-166

Intra-cellular tyrosine kinase

Rosalyn Irby, Timothy J. Yeatman, 2015, on p. 231-242

Intra-cellular tyrosine kinase

Rosalyn Irby, Timothy Yeatman, 2014, MOLECULAR ONCOLOGY: CAUSES OF CANCER AND TARGETS FOR TREATMENT on p. 231-242