Richard Mailman

Professor and College of Medicine Distinguished Senior Scholar

Richard Mailman

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Parkinson Disease Substantia Nigra Iron Short Term Memory Dopamine Agonists Dopamine Red Nucleus Therapeutics Pars Compacta Hydroxymethylglutaryl Coa Reductase Inhibitors Arrestin Pharmaceutical Preparations Prefrontal Cortex Pharmacology Dopamine D1 Receptors Schizophrenia Methylphenidate Dihydrexidine Brain Mentoring Manganese Genes Ligands Pars Reticulata Odds Ratio

Most Recent Publications

A Dopamine D<sub>1</sub> Agonist Versus Methylphenidate in Modulating Prefrontal Cortical Working Memory

Yang Yang, Mechelle M. Lewis, Lan Kong, Richard B. Mailman, 2022, Journal of Pharmacology and Experimental Therapeutics on p. 88-99

Dopamine D<sub>1</sub> receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior, and neurophysiology

Yang Yang, Mechelle Lewis, Xuemei Huang, Nikolay V. Dokholyan, Richard Mailman, 2022, International Journal of Biochemistry

Dose-Dependent Regulation on Prefrontal Neuronal Working Memory by Dopamine D<sub>1</sub> Agonists: Evidence of Receptor Functional Selectivity-Related Mechanisms

Yang Yang, Susan D. Kocher, Mechelle Lewis, Richard B. Mailman, 2022, Frontiers in Neuroscience

Higher R2* in the Red Nucleus Is Associated With Lead Exposure in an Asymptomatic Welder Cohort

Janina Manzieri Prado-Rico, Eun Young Lee, Ernest W. Wang, Jeff D. Yanosky, Lan Kong, Hairong Chen, Ana Navas-Acien, Guangwei Du, Mechelle Lewis, Richard B. Mailman, Xuemei Huang, 2022, Toxicological Sciences on p. 345-354

Dynamics of Nigral Iron Accumulation in Parkinson's Disease: From Diagnosis to Late Stage

Guangwei Du, Ernest Wang, Christopher Sica, Hairong Chen, Sol De Jesus, Mechelle Lewis, Lan Kong, James Connor, Richard B. Mailman, Xuemei Huang, 2022, Movement Disorders on p. 1654-1662

Clinician-Scientist Faculty Mentoring Program (FAME) – A New Inclusive Training Model at Penn State Increases Scholarly Productivity and Extramural Grant Funding

Sinisa Dovat, Chandrika Gowda, Richard B. Mailman, Leslie J. Parent, Xuemei Huang, 2022, Advances in Medical Education and Practice on p. 1039-1050

Low plasma serotonin linked to higher nigral iron in Parkinson’s disease

L Jellen, Mechelle M. Lewis, Guangwei Du, X Wang, Galvis MLE, Martha L.Escobar Galvis, S Krzyzanowski, C Capan, A Snyder, James R. Connor, Lan Kong, Richard B. Mailman, P Brundin, L Brundin, Xuemei Huang, 2021, Scientific Reports on p. 24384

Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D<sub>2</sub> receptor-dependent, manner

Jillian S. Weissenrieder, Jessie L. Reed, George Lucian Moldovan, Martin T. Johnson, Mohamed Trebak, Jeffrey D. Neighbors, Richard B. Mailman, Raymond J. Hohl, 2021, Pharmacology Research and Perspectives

Nigral MRI features of asymptomatic welders

Eun Young Lee, Michael R. Flynn, Guangwei Du, Mechelle M. Lewis, Michael Goldenberg, Lan Kong, Richard B. Mailman, Young Seoub Hong, Xuemei Huang, 2021, Parkinsonism and Related Disorders on p. 37-43

Building a System to Engage and Sustain Research Careers for Physicians

Xuemei Huang, S Dovat, Richard B. Mailman, Diane M. Thiboutot, D Berini, Leslie J. Parent, 2021, Academic Medicine on p. 490-494

Most-Cited Papers

Quantitative susceptibility mapping of the midbrain in Parkinson's disease

Guangwei Du, Tian Liu, Mechelle M. Lewis, Lan Kong, Yi Wang, James Connor, Richard B. Mailman, Xuemei Huang, 2016, Movement Disorders on p. 317-324

Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia

Amy F.T. Arnsten, Ragy R. Girgis, David L. Gray, Richard B. Mailman, 2017, Biological Psychiatry on p. 67-77

Statins, plasma cholesterol, and risk of Parkinson's disease: A prospective study

Xuemei Huang, Alvaro Alonso, Xuguang Guo, David M. Umbach, Maya L. Lichtenstein, Christie M. Ballantyne, Richard B. Mailman, Thomas H. Mosley, Honglei Chen, 2015, Movement Disorders on p. 552-559

Effects of the D<sub>1</sub> dopamine receptor agonist dihydrexidine (DAR-0100A) on working memory in schizotypal personality disorder

Daniel R. Rosell, Lauren C. Zaluda, Margaret M. McClure, M. Mercedes Perez-Rodriguez, K. Sloan Strike, Deanna M. Barch, Philip D. Harvey, Ragy R. Girgis, Erin A. Hazlett, Richard B. Mailman, Anissa Abi-Dargham, Jeffrey A. Lieberman, Larry J. Siever, 2015, Neuropsychopharmacology on p. 446-453

Projection of the prevalence of Parkinson's disease in the coming decades: Revisited

Alexander Rossi, Kristin Berger, Honglei Chen, Douglas Leslie, Richard Mailman, Xuemei Huang, 2018, Movement Disorders on p. 156-159

Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells

Xiaoli Zhang, Bing Li, Wenguo Li, Lijuan Ma, Dongyan Zheng, Leping Li, Weijing Yang, Min Chu, Wei Chen, Richard B. Mailman, Jun Zhu, Guoping Fan, Trevor K. Archer, Yuan Wang, 2014, Stem Cell Reports on p. 460-474

Higher iron in the red nucleus marks Parkinson's dyskinesia

Mechelle Lewis, Guangwei Du, Michal Kidacki, Nisargkumar Patel, Michele L. Shaffer, Richard Mailman, Xuemei Huang, 2013, Neurobiology of Aging on p. 1497-1503

Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database

Guodong Liu, Nicholas W. Sterling, Lan Kong, Mechelle M. Lewis, Richard B. Mailman, Honglei Chen, Douglas Leslie, Xuemei Huang, 2017, Movement Disorders on p. 913-917

Characterization of the neurochemical and behavioral effects of solriamfetol (JZP-110), a selective dopamine and norepinephrine reuptake inhibitor

Michelle G. Baladi, Michael J. Forster, Michael B. Gatch, Richard Mailman, Danielle L. Hyman, Lawrence P. Carter, Aaron Janowsky, 2018, Journal of Pharmacology and Experimental Therapeutics on p. 367-376

Distinct progression pattern of susceptibility MRI in the substantia nigra of Parkinson's patients

Guangwei Du, Mechelle Lewis, Christopher Sica, L He, James Connor, Lan Kong, Richard Mailman, Xuemei Huang, 2018, Movement Disorders on p. 1423-1431