Reyad Elbarbary

Associate Professor of Orthopaedics and Rehabilitation; Professor of Biochemistry and Molecular Biology

Reyad Elbarbary

Research Summary

Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.

Huck Affiliations

Publication Tags

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Cartilage Osteoarthritis Fracture Healing Messenger Rna Rna Tomography Proteins Meniscus Gene Expression Micrornas Therapeutics G Protein Coupled Receptor Kinase 2 Alu Elements Chondrocytes Bone And Bones Bone Electroporation Paroxetine 3' Untranslated Regions Bone Fractures Macrophages Joints Collagen Bony Callus Articular Cartilage

Most Recent Publications

Transcript shortening through alternative polyadenylation promotes gene expression during fracture healing

Reyad Elbarbary, Fadia Kamal, D Khajuria, I Nowak, M Leung, V Karuppagounder, Y Imamura, C Norbury, F Kamal, R Elbarbary, Bone Research

Transcript shortening via alternative polyadenylation promotes gene expression during fracture healing

Deepak Kumar Khajuria, Irena Nowak, Ming Leung, Vengadeshprabhu Karuppagounder, Yuka Imamura, Christopher C. Norbury, Fadia Kamal, Reyad A. Elbarbary, 2023, Bone Research

Musculoskeletal Research: Current Methods and Innovative Approaches

Reyad A. Elbarbary, 2023, Journal of Visualized Experiments

Cannabidiol and Cannabigerol, Nonpsychotropic Cannabinoids, as Analgesics that Effectively Manage Bone Fracture Pain and Promote Healing in Mice

Deepak Kumar Khajuria, Vengadeshprabhu Karuppagounder, Irena Nowak, Diana E. Sepulveda, Gregory Lewis, Christopher C. Norbury, Wesley M. Raup-Konsavage, Kent E. Vrana, Fadia Kamal, Reyad A. Elbarbary, 2023, Journal of Bone and Mineral Research

Distinct defects in early innate and late adaptive immune responses typify impaired fracture healing in diet-induced obesity

Deepak Kumar Khajuria, Irene Reider, Fadia Kamal, Christopher C. Norbury, Reyad A. Elbarbary, 2023, Frontiers in Immunology

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Fadia Kamal, Reyad Elbarbary, Hwa Bok Wee, H Wee, Deepak Kumar Khajuri, D Khajuria, Fadia Kamal, D Khajuria, F Kamal, Gregory Lewis, Reyad Elbarbary, G Lewis, 2022, Journal of Visualized Experiments

Distinctive Therapeutic Effects of Non-Euphorigenic Cannabis Extracts in Osteoarthritis.

V Karuppagounder, J Chung, A Abdeen, A Thompson, A Bouboukas, W Pinamont, N Yoshioka, D Sepulveda, W Raup-Konsavage, N Graziane, K Vrana, Reyad Elbarbary, Fadia Kamal, 2022, Cannabis and cannabinoid research

Early Gβγ-GRK2 Inhibition Ameliorates Osteoarthritis Development by Simultaneous Anti-Inflammatory and Chondroprotective Effects

V Karuppagounder, W Pinamont, N Yoshioka, Reyad Elbarbary, Fadia Kamal, 2022, International Journal of Molecular Sciences

Structural changes in the collagen network of joint tissues in late stages of murine OA

N Yoshioka, G Young, D Khajuria, V Karuppagounder, W Pinamont, Julie C. Fanburg-Smith, T Abraham, Reyad A. Elbarbary, Fadia Kamal, 2022, Scientific Reports on p. 9159

GRK2, a novel regulator of skeletal development

Natalie K. Yoshioka, Vengadeshprabhu Karuppagounder, William J. Pinamont, Gina M. Deiter, Reyad A. Elbarbary, Maurizio Pacifici, Fadia Kamal, 2022, FASEB Journal

Most-Cited Papers

Retrotransposons as regulators of gene expression

Reyad A. Elbarbary, Bronwyn A. Lucas, Lynne E. Maquat, 2016, Science

STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown

Reyad A. Elbarbary, Wencheng Li, Bin Tian, Lynne E. Maquat, 2013, Genes and Development on p. 1495-1510

Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition

Reyad A. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du, John M. Ashton, Bin Tian, Lynne E. Maquat, 2017, Science on p. 859-862

Extraction of high-quality RNA from human articular cartilage

Heather K. Le Bleu, Fadia A. Kamal, Meghan Kelly, John P. Ketz, Michael J. Zuscik, Reyad A. Elbarbary, 2017, Analytical Biochemistry on p. 134-138

UPF1 helicase promotes TSN-mediated miRNA decay

Reyad A. Elbarbary, Keita Miyoshi, Omar Hedaya, Jason R. Myers, Lynne E. Maquat, 2017, Genes and Development on p. 1483-1493

Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis

Elijah L. Carlson, Vengadeshprabhu Karuppagounder, William J. Pinamont, Natalie K. Yoshioka, Adeel Ahmad, Eric M. Schott, Heather K. Le Bleu, Michael J. Zuscik, Reyad A. Elbarbary, Fadia Kamal, 2021, Science Translational Medicine

A naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells

Masayuki Takahashi, Reyad A. Elbarbary, Aiko Nakashima, Mayumi Abe, Norihiro Watanabe, Miwako Narita, Masuhiro Takahashi, Masato Tamura, Tetsuo Yoshida, Masayuki Nashimoto, 2013, Cancer Letters on p. 362-368

Aberrant structure of fibrillar collagen and elevated levels of advanced glycation end products typify delayed fracture healing in the diet-induced obesity mouse model

Deepak Khajuria, Marwa Soliman, John Elfar, Gregory Lewis, Thomas Abraham, Fadia Kamal, Reyad A. Elbarbary, 2020, Bone on p. 115436

Standardized histomorphometric evaluation of osteoarthritis in a surgical mouse model

William J. Pinamont, Natalie K. Yoshioka, Gregory M. Young, Vengadeshprabhu Karuppagounder, Elijah L. Carlson, Adeel Ahmad, Reyad Elbarbary, Fadia Kamal, 2020, Journal of Visualized Experiments

CARMing down the SINEs of anarchy: Two paths to freedom from paraspeckle detention

Reyad A. Elbarbary, Lynne E. Maquat, 2015, Genes and Development on p. 687-689