Reyad Elbarbary
Associate Professor of Orthopaedics and Rehabilitation; Professor of Biochemistry and Molecular Biology

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H089 Orthopedics & Rehabilitation
Hershey, PA - rae19@psu.edu
- 717-531-4836
Research Summary
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Huck Affiliations
Publication Tags
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Cartilage Osteoarthritis Fracture Healing Messenger Rna Rna Tomography Proteins Meniscus Gene Expression Micrornas Therapeutics G Protein Coupled Receptor Kinase 2 Alu Elements Chondrocytes Bone And Bones Bone Electroporation Paroxetine 3' Untranslated Regions Bone Fractures Macrophages Joints Collagen Bony Callus Articular CartilageMost Recent Publications
Transcript shortening through alternative polyadenylation promotes gene expression during fracture healing
Reyad Elbarbary, Fadia Kamal, D Khajuria, I Nowak, M Leung, V Karuppagounder, Y Imamura, C Norbury, F Kamal, R Elbarbary, Bone Research
Transcript shortening via alternative polyadenylation promotes gene expression during fracture healing
Deepak Kumar Khajuria, Irena Nowak, Ming Leung, Vengadeshprabhu Karuppagounder, Yuka Imamura, Christopher C. Norbury, Fadia Kamal, Reyad A. Elbarbary, 2023, Bone Research
Musculoskeletal Research: Current Methods and Innovative Approaches
Reyad A. Elbarbary, 2023, Journal of Visualized Experiments
Cannabidiol and Cannabigerol, Nonpsychotropic Cannabinoids, as Analgesics that Effectively Manage Bone Fracture Pain and Promote Healing in Mice
Deepak Kumar Khajuria, Vengadeshprabhu Karuppagounder, Irena Nowak, Diana E. Sepulveda, Gregory Lewis, Christopher C. Norbury, Wesley M. Raup-Konsavage, Kent E. Vrana, Fadia Kamal, Reyad A. Elbarbary, 2023, Journal of Bone and Mineral Research
Distinct defects in early innate and late adaptive immune responses typify impaired fracture healing in diet-induced obesity
Deepak Kumar Khajuria, Irene Reider, Fadia Kamal, Christopher C. Norbury, Reyad A. Elbarbary, 2023, Frontiers in Immunology
Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Fadia Kamal, Reyad Elbarbary, Hwa Bok Wee, H Wee, Deepak Kumar Khajuri, D Khajuria, Fadia Kamal, D Khajuria, F Kamal, Gregory Lewis, Reyad Elbarbary, G Lewis, 2022, Journal of Visualized Experiments
Distinctive Therapeutic Effects of Non-Euphorigenic Cannabis Extracts in Osteoarthritis.
V Karuppagounder, J Chung, A Abdeen, A Thompson, A Bouboukas, W Pinamont, N Yoshioka, D Sepulveda, W Raup-Konsavage, N Graziane, K Vrana, Reyad Elbarbary, Fadia Kamal, 2022, Cannabis and cannabinoid research
Early Gβγ-GRK2 Inhibition Ameliorates Osteoarthritis Development by Simultaneous Anti-Inflammatory and Chondroprotective Effects
V Karuppagounder, W Pinamont, N Yoshioka, Reyad Elbarbary, Fadia Kamal, 2022, International Journal of Molecular Sciences
Structural changes in the collagen network of joint tissues in late stages of murine OA
N Yoshioka, G Young, D Khajuria, V Karuppagounder, W Pinamont, Julie C. Fanburg-Smith, T Abraham, Reyad A. Elbarbary, Fadia Kamal, 2022, Scientific Reports on p. 9159
GRK2, a novel regulator of skeletal development
Natalie K. Yoshioka, Vengadeshprabhu Karuppagounder, William J. Pinamont, Gina M. Deiter, Reyad A. Elbarbary, Maurizio Pacifici, Fadia Kamal, 2022, FASEB Journal
Most-Cited Papers
Retrotransposons as regulators of gene expression
Reyad A. Elbarbary, Bronwyn A. Lucas, Lynne E. Maquat, 2016, Science
STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown
Reyad A. Elbarbary, Wencheng Li, Bin Tian, Lynne E. Maquat, 2013, Genes and Development on p. 1495-1510
Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition
Reyad A. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du, John M. Ashton, Bin Tian, Lynne E. Maquat, 2017, Science on p. 859-862
Extraction of high-quality RNA from human articular cartilage
Heather K. Le Bleu, Fadia A. Kamal, Meghan Kelly, John P. Ketz, Michael J. Zuscik, Reyad A. Elbarbary, 2017, Analytical Biochemistry on p. 134-138
UPF1 helicase promotes TSN-mediated miRNA decay
Reyad A. Elbarbary, Keita Miyoshi, Omar Hedaya, Jason R. Myers, Lynne E. Maquat, 2017, Genes and Development on p. 1483-1493
Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis
Elijah L. Carlson, Vengadeshprabhu Karuppagounder, William J. Pinamont, Natalie K. Yoshioka, Adeel Ahmad, Eric M. Schott, Heather K. Le Bleu, Michael J. Zuscik, Reyad A. Elbarbary, Fadia Kamal, 2021, Science Translational Medicine
A naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells
Masayuki Takahashi, Reyad A. Elbarbary, Aiko Nakashima, Mayumi Abe, Norihiro Watanabe, Miwako Narita, Masuhiro Takahashi, Masato Tamura, Tetsuo Yoshida, Masayuki Nashimoto, 2013, Cancer Letters on p. 362-368
Aberrant structure of fibrillar collagen and elevated levels of advanced glycation end products typify delayed fracture healing in the diet-induced obesity mouse model
Deepak Khajuria, Marwa Soliman, John Elfar, Gregory Lewis, Thomas Abraham, Fadia Kamal, Reyad A. Elbarbary, 2020, Bone on p. 115436
Standardized histomorphometric evaluation of osteoarthritis in a surgical mouse model
William J. Pinamont, Natalie K. Yoshioka, Gregory M. Young, Vengadeshprabhu Karuppagounder, Elijah L. Carlson, Adeel Ahmad, Reyad Elbarbary, Fadia Kamal, 2020, Journal of Visualized Experiments
CARMing down the SINEs of anarchy: Two paths to freedom from paraspeckle detention
Reyad A. Elbarbary, Lynne E. Maquat, 2015, Genes and Development on p. 687-689
News Articles Featuring Reyad Elbarbary
Oct 27, 2023
CBD and CBG may promote bone fracture healing, manage pain
Cannabidiol (CBD) and cannabigerol (CBG) might someday help bone fracture patients manage their pain
Full Article
Oct 27, 2023
2 cannabis compounds may boost pain relief, speed up healing of fractured bones
Two compounds found in cannabis may offer hope to bone fracture patients for pain management and even accelerated healing
Full Article
Oct 24, 2023
CBD and CBG may promote bone fracture healing, manage pain
Cannabidiol (CBD) and cannabigerol (CBG) might someday help bone fracture patients manage their pain, according to a Penn State study.
Full Article
Jun 12, 2023
Penn State announces tenure-line faculty promotions, effective July 1, 2023
The following is a list of academic promotions for tenured and tenure-line faculty members at Penn State, effective July 1, 2023.
Full Article