Reyad Elbarbary

Assistant Professor of Orthopaedics

Reyad  Elbarbary

Research Summary

Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.

Huck Affiliations

Publication Tags

Rna Micrornas Messenger Rna Cartilage Therapeutics Guide Rna Rna Precursors Gene Expression Alu Elements Cell Nucleus Active Transport Proteins Micrococcal Nuclease Articular Cartilage G1 Phase Regulator Genes Osteoarthritis Phase Transition Genome S Phase Retroelements Hl 60 Cells Gene Silencing Cytoplasm Genes In Vitro Techniques

Most Recent Papers

Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis

Elijah L. Carlson, Vengadeshprabhu Karuppagounder, William J. Pinamont, Natalie K. Yoshioka, Adeel Ahmad, Eric M. Schott, Heather K. Le Bleu, Michael J. Zuscik, Reyad A. Elbarbary, Fadia Kamal, 2021, Science Translational Medicine

Standardized histomorphometric evaluation of osteoarthritis in a surgical mouse model

William J. Pinamont, Natalie K. Yoshioka, Gregory M. Young, Vengadeshprabhu Karuppagounder, Elijah L. Carlson, Adeel Ahmad, Reyad Elbarbary, Fadia Kamal, 2020, Journal of Visualized Experiments

Evaluating the susceptibility of AGO2-loaded microRNAs to degradation by nucleases in vitro

Reyad A. Elbarbary, Lynne E. Maquat, 2019, ImmunoMethods on p. 18-22

Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism

Reyad A. Elbarbary, Lynne E. Maquat, 2017, Nature Structural Biology on p. 496-498

Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition

Reyad A. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du, John M. Ashton, Bin Tian, Lynne E. Maquat, 2017, Science on p. 859-862

Extraction of high-quality RNA from human articular cartilage

Heather K. Le Bleu, Fadia A. Kamal, Meghan Kelly, John P. Ketz, Michael J. Zuscik, Reyad A. Elbarbary, 2017, Analytical Biochemistry on p. 134-138

UPF1 helicase promotes TSN-mediated miRNA decay

Reyad A. Elbarbary, Keita Miyoshi, Omar Hedaya, Jason R. Myers, Lynne E. Maquat, 2017, Genes and Development on p. 1483-1493

Coupling pre-mRNA splicing and 3′ end formation to mRNA export: Alternative ways to punch the nuclear export clock

Reyad Elbarbary, Lynne Maquat, 2016, Genes and Development on p. 487-488

Retrotransposons as regulators of gene expression

Reyad A. Elbarbary, Bronwyn A. Lucas, Lynne E. Maquat, 2016, Science

CARMing down the SINEs of anarchy: Two paths to freedom from paraspeckle detention

Reyad Elbarbary, Lynne Maquat, 2015, Genes and Development on p. 687-689

Most-Cited Papers

Retrotransposons as regulators of gene expression

Reyad A. Elbarbary, Bronwyn A. Lucas, Lynne E. Maquat, 2016, Science

STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown

Reyad A. Elbarbary, Wencheng Li, Bin Tian, Lynne E. Maquat, 2013, Genes and Development on p. 1495-1510

Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition

Reyad A. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du, John M. Ashton, Bin Tian, Lynne E. Maquat, 2017, Science on p. 859-862

A novel phenylpyridazinone, T-3999, reduces the progression of autoimmune myocarditis to dilated cardiomyopathy

Fadia Ali Kamal, Kenichi Watanabe, Meilei Ma, Yuichi Abe, Reyad Elbarbary, Makoto Kodama, Yoshifusa Aizawa, 2011, Heart and Vessels on p. 81-90

UPF1 helicase promotes TSN-mediated miRNA decay

Reyad A. Elbarbary, Keita Miyoshi, Omar Hedaya, Jason R. Myers, Lynne E. Maquat, 2017, Genes and Development on p. 1483-1493

Extraction of high-quality RNA from human articular cartilage

Heather K. Le Bleu, Fadia A. Kamal, Meghan Kelly, John P. Ketz, Michael J. Zuscik, Reyad A. Elbarbary, 2017, Analytical Biochemistry on p. 134-138

A naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells

Masayuki Takahashi, Reyad A. Elbarbary, Aiko Nakashima, Mayumi Abe, Norihiro Watanabe, Miwako Narita, Masuhiro Takahashi, Masato Tamura, Tetsuo Yoshida, Masayuki Nashimoto, 2013, Cancer Letters on p. 362-368

Elimination of specific miRNAs by naked 14-nt sgRNAs

Masayuki Takahashi, Reyad A. Elbarbary, Mayumi Abe, Mari Sato, Tetsuo Yoshida, Yoji Yamada, Masato Tamura, Masayuki Nashimoto, 2012, PLoS One

Screening of a heptamer-type sgRNA library for potential therapeutic agents against hematological malignancies

Masayuki Takahashi, Reyad A. Elbarbary, Norihiro Watanabe, Atsushi Goto, Daichi Kamiya, Yoshihiro Watabe, Takayoshi Uchiyama, Miwako Narita, Masuhiro Takahashi, Yoshiaki Takahashi, Noriko Ishihara, Tatsuya Miyazawa, Tetsuo Yoshida, Mitsuoki Kawano, Masato Tamura, Masayuki Nashimoto, 2014, Leukemia Research on p. 808-815

Coupling pre-mRNA splicing and 3′ end formation to mRNA export: Alternative ways to punch the nuclear export clock

Reyad Elbarbary, Lynne Maquat, 2016, Genes and Development on p. 487-488