Reyad Elbarbary
Assistant Professor of Orthopaedics
- H089 Orthopedics & Rehabilitation
Hershey, PA - rae19@psu.edu
- 717-531-4836
Research Summary
Roles of non-coding RNAs and retrotransposons in musculoskeletal diseases.
Huck Institutes Affiliations
Publication Tags
Rna Messenger Rna Micrornas Guide Rna Gene Expression Alu Elements Gene Silencing 3' Untranslated Regions Therapeutics Apoptosis Technology Hl 60 Cells Leukemia Genes Direction Compound Hematologic Neoplasms Transfer Rna Cytoplasm Down Regulation Cell Nucleus Active Transport In Vitro Techniques Rna Precursors Protein Kinases Vascular Endothelial Growth Factor A Phase TransitionMost Recent Papers
Evaluating the susceptibility of AGO2-loaded microRNAs to degradation by nucleases in vitro
Reyad A. Elbarbary, Lynne E. Maquat, 2018, Methods
Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism
Reyad A. Elbarbary, Lynne E. Maquat, 2017, Nature Structural and Molecular Biology on p. 496-498
Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition
Reyad A. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du, John M. Ashton, Bin Tian, Lynne E. Maquat, 2017, Science on p. 859-862
Extraction of high-quality RNA from human articular cartilage
Heather K. Le Bleu, Fadia A. Kamal, Meghan Kelly, John P. Ketz, Michael J. Zuscik, Reyad A. Elbarbary, 2017, Analytical Biochemistry on p. 134-138
UPF1 helicase promotes TSN-mediated miRNA decay
Reyad A. Elbarbary, Keita Miyoshi, Omar Hedaya, Jason R. Myers, Lynne E. Maquat, 2017, Genes and Development on p. 1483-1493
Coupling pre-mRNA splicing and 3′ end formation to mRNA export
Reyad A. Elbarbary, Lynne E. Maquat, 2016, Genes and Development on p. 487-488
CARMing down the SINEs of anarchy
Reyad A. Elbarbary, Lynne E. Maquat, 2015, Genes and Development on p. 687-689
Screening of a heptamer-type sgRNA library for potential therapeutic agents against hematological malignancies
Masayuki Takahashi, Reyad A. Elbarbary, Norihiro Watanabe, Atsushi Goto, Daichi Kamiya, Yoshihiro Watabe, Takayoshi Uchiyama, Miwako Narita, Masuhiro Takahashi, Yoshiaki Takahashi, Noriko Ishihara, Tatsuya Miyazawa, Tetsuo Yoshida, Mitsuoki Kawano, Masato Tamura, Masayuki Nashimoto, 2014, Leukemia Research on p. 808-815
STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown
Reyad A. Elbarbary, Wencheng Li, Bin Tian, Lynne E. Maquat, 2013, Genes and Development on p. 1495-1510
A naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells
Masayuki Takahashi, Reyad A. Elbarbary, Aiko Nakashima, Mayumi Abe, Norihiro Watanabe, Miwako Narita, Masuhiro Takahashi, Masato Tamura, Tetsuo Yoshida, Masayuki Nashimoto, 2013, Cancer Letters on p. 362-368
High-Impact Papers
Modulation of gene expression by human cytosolic tRNase Z<sup>L</sup> through 5′-half-tRNA
Reyad A. Elbarbary, Hiroaki Takaku, Naoto Uchiumi, Hiroko Tamiya, Mayumi Abe, Masayuki Takahashi, Hiroshi Nishida, Masayuki Nashimoto, 2009, PLoS One
STAU1 binding 3′ UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown
Reyad A. Elbarbary, Wencheng Li, Bin Tian, Lynne E. Maquat, 2013, Genes and Development on p. 1495-1510
Human cytosolic tRNase Z<sup>L</sup> can downregulate gene expression through miRNA
Reyad A. Elbarbary, Hiroaki Takaku, Naoto Uchiumi, Hiroko Tamiya, Mayumi Abe, Hiroshi Nishida, Masayuki Nashimoto, 2009, FEBS Letters on p. 3241-3246
A novel phenylpyridazinone, T-3999, reduces the progression of autoimmune myocarditis to dilated cardiomyopathy
Fadia Ali Kamal, Kenichi Watanabe, Meilei Ma, Yuichi Abe, Reyad Elbarbary, Makoto Kodama, Yoshifusa Aizawa, 2011, Heart and Vessels on p. 81-90
Inhibition of vascular endothelial growth factor expression by TRUE gene silencing
Reyad A. Elbarbary, Hiroaki Takaku, Masato Tamura, Masayuki Nashimoto, 2009, Biochemical and Biophysical Research Communications on p. 924-927
A naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells
Masayuki Takahashi, Reyad A. Elbarbary, Aiko Nakashima, Mayumi Abe, Norihiro Watanabe, Miwako Narita, Masuhiro Takahashi, Masato Tamura, Tetsuo Yoshida, Masayuki Nashimoto, 2013, Cancer Letters on p. 362-368
Elimination of specific miRNAs by naked 14-nt sgRNAs
Masayuki Takahashi, Reyad A. Elbarbary, Mayumi Abe, Mari Sato, Tetsuo Yoshida, Yoji Yamada, Masato Tamura, Masayuki Nashimoto, 2012, PLoS One
Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition
Reyad A. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du, John M. Ashton, Bin Tian, Lynne E. Maquat, 2017, Science on p. 859-862
CARMing down the SINEs of anarchy
Reyad A. Elbarbary, Lynne E. Maquat, 2015, Genes and Development on p. 687-689
Screening of a heptamer-type sgRNA library for potential therapeutic agents against hematological malignancies
Masayuki Takahashi, Reyad A. Elbarbary, Norihiro Watanabe, Atsushi Goto, Daichi Kamiya, Yoshihiro Watabe, Takayoshi Uchiyama, Miwako Narita, Masuhiro Takahashi, Yoshiaki Takahashi, Noriko Ishihara, Tatsuya Miyazawa, Tetsuo Yoshida, Mitsuoki Kawano, Masato Tamura, Masayuki Nashimoto, 2014, Leukemia Research on p. 808-815