Rebecca Craven
Professor of Microbiology & Immunology
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H107 Microbiology & Immunology
Hershey, PA - rcc6@psu.edu
- 717-531-3528
Huck Affiliations
Publication Tags
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Capsid Rous Sarcoma Virus Capsid Proteins Viruses Virus Assembly Mutation Proteins Tomography Protein Dimerization Protein C Virion Retroviridae Temperature Molecular Dynamics Simulation In Vitro Techniques Electrons Peptides Cells Cell Fusion Structural Models Mutagenesis Nucleocapsid Trimer Human Alphaherpesvirus 1Most Recent Publications
The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B
Jillian C. Carmichael, Hiroki Yokota, Rebecca C. Craven, Anthony Schmitt, John W. Wills, 2018, PLoS Pathogens
Structural model of the tubular assembly of the rous sarcoma virus capsid protein
Jaekyun Jeon, Xin Qiao, Ivan Hung, Alok K. Mitra, Ambroise Desfosses, Daniel Huang, Peter L. Gorkov, Rebecca C. Craven, Richard L. Kingston, Zhehong Gan, Fangqiang Zhu, Bo Chen, 2017, Journal of the American Chemical Society on p. 2006-2013
Contributions of charged residues in structurally dynamic capsid surface loops to Rous sarcoma virus assembly
Katrina J. Heyrana, Boon Chong Goh, Juan R. Perilla, Tam Linh N. Nguyen, Matthew R. England, Maria C. Bewley, Klaus Schulten, Rebecca C. Craven, 2016, Journal of Virology on p. 5700-5714
Atomic Modeling of an Immature Retroviral Lattice Using Molecular Dynamics and Mutagenesis
Boon Chong Goh, Juan R. Perilla, Matthew R. England, Katrina J. Heyrana, Rebecca C. Craven, Klaus Schulten, 2015, Structure with Folding & design on p. 1414-1425
A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition
Paul W. Keller, Rick K. Huang, Matthew R. England, Kayoko Waki, Naiqian Cheng, J. Bernard Heymann, Rebecca C. Craven, Eric O. Freed, Alasdair C. Steven, 2013, Journal of Virology on p. 13655-13664
Lethal mutations in the major homology region and their suppressors act by modulating the dimerization of the rous sarcoma virus capsid protein C-terminal domain
Paula Dalessio, Rebecca Craven, Parvez M. Lokhandwala, Ira Ropson, 2013, Proteins: Structure, Function and Genetics on p. 316-325
Suppression of a morphogenic mutant in Rous sarcoma virus capsid protein by a second-site mutation: A cryoelectron tomography study
Carmen Butan, Parvez M. Lokhandwala, John G. Purdy, Giovanni Cardone, Rebecca C. Craven, Alasdair C. Steven, 2010, Journal of Virology on p. 6377-6386
Electron-tomography of a temperature-sensitive morphogenic mutant of rous sarcoma virus (RSV)
C. Butan, P. M. Lokhandwala, D. C. Winkler, R. C. Craven, A. C. Steven, 2009, Microscopy and Microanalysis on p. 646-647
Retroviral Capsid Assembly: A Role for the CA Dimer in Initiation
John G. Purdy, John M. Flanagan, Ira J. Ropson, Rebecca C. Craven, 2009, Journal of Molecular Biology on p. 438-451
Visualization of a missing link in retrovirus capsid assembly
Giovanni Cardone, John G. Purdy, Naiqian Cheng, Rebecca C. Craven, Alasdair C. Steven, 2009, Nature on p. 694-698
Most-Cited Papers
A two-pronged structural analysis of retroviral maturation indicates that core formation proceeds by a disassembly-reassembly pathway rather than a displacive transition
Paul W. Keller, Rick K. Huang, Matthew R. England, Kayoko Waki, Naiqian Cheng, J. Bernard Heymann, Rebecca C. Craven, Eric O. Freed, Alasdair C. Steven, 2013, Journal of Virology on p. 13655-13664
Atomic Modeling of an Immature Retroviral Lattice Using Molecular Dynamics and Mutagenesis
Boon Chong Goh, Juan R. Perilla, Matthew R. England, Katrina J. Heyrana, Rebecca C. Craven, Klaus Schulten, 2015, Structure with Folding & design on p. 1414-1425
The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B
Jillian C. Carmichael, Hiroki Yokota, Rebecca C. Craven, Anthony Schmitt, John W. Wills, 2018, PLoS Pathogens
Contributions of charged residues in structurally dynamic capsid surface loops to Rous sarcoma virus assembly
Katrina J. Heyrana, Boon Chong Goh, Juan R. Perilla, Tam Linh N. Nguyen, Matthew R. England, Maria C. Bewley, Klaus Schulten, Rebecca C. Craven, 2016, Journal of Virology on p. 5700-5714
Structural model of the tubular assembly of the rous sarcoma virus capsid protein
Jaekyun Jeon, Xin Qiao, Ivan Hung, Alok K. Mitra, Ambroise Desfosses, Daniel Huang, Peter L. Gorkov, Rebecca C. Craven, Richard L. Kingston, Zhehong Gan, Fangqiang Zhu, Bo Chen, 2017, Journal of the American Chemical Society on p. 2006-2013
Lethal mutations in the major homology region and their suppressors act by modulating the dimerization of the rous sarcoma virus capsid protein C-terminal domain
Paula Dalessio, Rebecca Craven, Parvez M. Lokhandwala, Ira Ropson, 2013, Proteins: Structure, Function and Genetics on p. 316-325