Qunhua Li

Associate Professor of Statistics

Qunhua Li

Research Summary

Developing statistical and computational methods for analyzing complex omics data and improving quality and reproducibility of high-throughout data

Graduate Students

Huck Affiliations

Publication Tags

Genes Dna Gene Expression Statistical Models Proteins Mass Spectrometry Chromatin Interleukin 6 Peptides Reproducibility Change Point Galaxies Genome Gene Experiment Diet Protein Methodology Mixture Model Model Enzymes Analysis Colon Chip Population

Most Recent Papers

OnTAD

Lin An, Tao Yang, Jiahao Yang, Johannes Nuebler, Guanjue Xiang, Ross C. Hardison, Qunhua Li, Yu Zhang, 2019, Genome biology on p. 1-16

Measuring the reproducibility and quality of Hi-C data

Galip Gürkan Yardımcı, Hakan Ozadam, Michael E.G. Sauria, Oana Ursu, Koon Kiu Yan, Tao Yang, Abhijit Chakraborty, Arya Kaul, Bryan R. Lajoie, Fan Song, Ye Zhan, Ferhat Ay, Mark Gerstein, Anshul Kundaje, Qunhua Li, James Taylor, Feng Yue, Job Dekker, William S. Noble, 2019, Genome biology

A continuous threshold expectile model

Feipeng Zhang, Qunhua Li, 2017, Computational Statistics and Data Analysis on p. 49-66

Pigs, unlike mice, have two distinct colonic stem cell populations similar to humans that respond to high-calorie diet prior to insulin resistance

Venkata Charepalli, Lavanya Reddivari, Sridhar Radhakrishnan, Elisabeth Eriksson, Xia Xiao, Sung Woo Kim, Frank Shen, Matam Vijay-Kumar, Qunhua Li, Vadiraja B. Bhat, Rob Knight, Jairam K.P. Vanamala, 2017, Cancer Prevention Research on p. 442-450

Robust bent line regression

Feipeng Zhang, Qunhua Li, 2017, Journal of Statistical Planning and Inference on p. 41-55

A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis

Abigail Sido, Sridhar Radhakrishnan, Sung Woo Kim, Elisabeth Eriksson, Frank Shen, Qunhua Li, Vadiraja Bhat, Lavanya Reddivari, Jairam K.P. Vanamala, 2017, Journal of Nutritional Biochemistry on p. 11-17

A semi-parametric statistical model for integrating gene expression profiles across different platforms

Yafei Lyu, Qunhua Li, 2016, BMC bioinformatics

Multi-scale biological and physical modelling of the tumour micro-environment

Robert F. Kunz, Byron J. Gaskin, Qunhua Li, Sam Davanloo-Tajbakhsh, Cheng Dong, 2015, Drug Discovery Today: Disease Models on p. 7-15

Practical Guidelines for the Comprehensive Analysis of ChIP-seq Data

Timothy Bailey, Pawel Krajewski, Istvan Ladunga, Celine Lefebvre, Qunhua Li, Tao Liu, Pedro Madrigal, Cenny Taslim, Jie Zhang, 2013, PLoS computational biology

Galaxy tools to study genome diversity

Oscar C. Bedoya-Reina, Aakrosh Ratan, Richard Burhans, Hie Lim Kim, Belinda Giardine, Cathy Riemer, Qunhua Li, Thomas L. Olson, Thomas P. Loughran, Bridgett M. vonHoldt, George H. Perry, Stephan C. Schuster, Webb Miller, 2013, GigaScience

Most-Cited Papers

Measuring reproducibility of high-throughput experiments

Qunhua Li, James B. Brown, Haiyan Huang, Peter J. Bickel, 2011, Annals of Applied Statistics on p. 1752-1779

Practical Guidelines for the Comprehensive Analysis of ChIP-seq Data

Timothy Bailey, Pawel Krajewski, Istvan Ladunga, Celine Lefebvre, Qunhua Li, Tao Liu, Pedro Madrigal, Cenny Taslim, Jie Zhang, 2013, PLoS computational biology

A nested mixture model for protein identification using mass spectrometry

Qunhua Li, Michael J. MacCoss, Matthew Stephens, 2010, Annals of Applied Statistics on p. 962-987

Galaxy tools to study genome diversity

Oscar C. Bedoya-Reina, Aakrosh Ratan, Richard Burhans, Hie Lim Kim, Belinda Giardine, Cathy Riemer, Qunhua Li, Thomas L. Olson, Thomas P. Loughran, Bridgett M. vonHoldt, George H. Perry, Stephan C. Schuster, Webb Miller, 2013, GigaScience

A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis

Abigail Sido, Sridhar Radhakrishnan, Sung Woo Kim, Elisabeth Eriksson, Frank Shen, Qunhua Li, Vadiraja Bhat, Lavanya Reddivari, Jairam K.P. Vanamala, 2017, Journal of Nutritional Biochemistry on p. 11-17

Measuring the reproducibility and quality of Hi-C data

Galip Gürkan Yardımcı, Hakan Ozadam, Michael E.G. Sauria, Oana Ursu, Koon Kiu Yan, Tao Yang, Abhijit Chakraborty, Arya Kaul, Bryan R. Lajoie, Fan Song, Ye Zhan, Ferhat Ay, Mark Gerstein, Anshul Kundaje, Qunhua Li, James Taylor, Feng Yue, Job Dekker, William S. Noble, 2019, Genome biology

A semi-parametric statistical model for integrating gene expression profiles across different platforms

Yafei Lyu, Qunhua Li, 2016, BMC bioinformatics

A likelihood-based scoring method for peptide identification using mass spectrometry

Qunhua Li, Jimmy K. Eng, Matthew Stephens, 2012, Annals of Applied Statistics on p. 1775-1794

Robust bent line regression

Feipeng Zhang, Qunhua Li, 2017, Journal of Statistical Planning and Inference on p. 41-55

A continuous threshold expectile model

Feipeng Zhang, Qunhua Li, 2017, Computational Statistics and Data Analysis on p. 49-66