Philip Smith

Director, Metabolomics Core Facility; Senior Research Associate, Proteomics and Mass Spectrometry Core Facility (University Park)

Philip Smith

Publication Tags

Metabolomics Liver Aryl Hydrocarbon Receptors Glucose Fatty Acids Toxicity Nuclear Magnetic Resonance Lipid Metabolism Metabolism Mass Spectrometry Gastrointestinal Microbiome Microbiota Amino Acids Genes Flow Cytometry Physiology Chemical Activation Biofuels Oxygen Methane Obesity Phenotype Homeostasis Lipids Xenobiotics

Most Recent Papers

Microbiota Metabolism Promotes Synthesis of the Human Ah Receptor Agonist 2,8-Dihydroxyquinoline

Troy D. Hubbard, Qing Liu, Iain Alexander Murray, Fangcong Dong, Charles Miller, Philip B. Smith, Krishne Gowda, Jyh Ming Lin, Shantu Amin, Andrew David Patterson, Gary H. Perdew, 2019, Journal of Proteome Research on p. 1715-1724

Metabolomic Approaches Reveal the Role of CAR in Energy Metabolism

Fengming Chen, Denise M. Coslo, Tao Chen, Limin Zhang, Yuan Tian, Philip B. Smith, Andrew David Patterson, Curtis John Omiecinski, 2019, Journal of Proteome Research on p. 239-251

Structural and Functional Analysis of the Gut Microbiome for Toxicologists

Robert G. Nichols, Jingwei Cai, Iain Alexander Murray, Imhoi Koo, Philip B. Smith, Gary H. Perdew, Andrew David Patterson, 2018, Current Protocols in Toxicology

Multiplatform physiologic and metabolic phenotyping reveals microbial toxicity

Jingwei Cai, Robert G. Nichols, Imhoi Koo, Zachary A. Kalikow, Limin Zhang, Yuan Tian, Jingtao Zhang, Philip B. Smith, Andrew David Patterson, 2018, mSystems

The association of lipophilic phospholipids with native bovine casein micelles in skim milk

M. Cheema, Philip B. Smith, A. D. Patterson, Alexander Nikolov Hristov, Federico Miguel Harte, 2018, Journal of dairy science on p. 8672-8687

Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice

Yuan Tian, Robert G. Nichols, Pratiti Roy, Wei Gui, Philip B. Smith, Jingtao Zhang, Yangding Lin, Veronika Weaver, Jingwei Cai, Andrew David Patterson, Margherita Teresa-Anna Cantorna, 2018, Journal of Functional Foods on p. 223-232

Regulation of vitamin D metabolism following disruption of the microbiota using broad spectrum antibiotics

Stephanie A. Bora, Mary J. Kennett, Philip B. Smith, Andrew David Patterson, Margherita Teresa-Anna Cantorna, 2018, Journal of Nutritional Biochemistry on p. 65-73

Metabolomics Reveals Aryl Hydrocarbon Receptor Activation Induces Liver and Mammary Gland Metabolic Dysfunction in Lactating Mice

Kerry R. Belton, Yuan Tian, Limin Zhang, Mallappa Anitha, Philip B. Smith, Gary H. Perdew, Andrew David Patterson, 2018, Journal of Proteome Research on p. 1375-1382

The gut microbiota regulates endocrine vitamin D metabolism through fibroblast growth factor 23

Stephanie A. Bora, Mary J. Kennett, Philip B. Smith, Andrew David Patterson, Margherita Teresa-Anna Cantorna, 2018, Frontiers in immunology

Enzyme polymorphism, oxygen and injury

Julianne E. Pekny, Philip B. Smith, James Harold Marden, 2018, Journal of Experimental Biology

High-Impact Papers

Persistent organic pollutants modify gut microbiota–host metabolic homeostasis in mice through aryl hydrocarbon receptor activation

Limin Zhang, Robert G. Nichols, Jared Correll, Iain Alexander Murray, Naoki Tanaka, Philip B. Smith, Troy D. Hubbard, Aswathy Sebastian, Istvan Albert, Emmanuel Hatzakis, Frank J. Gonzalez, Gary H. Perdew, Andrew David Patterson, 2015, Environmental health perspectives on p. 679-688

Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer

Ewy A. Mathé, Andrew David Patterson, Majda Haznadar, Soumen K. Manna, Kristopher W. Krausz, Elise D. Bowman, Peter G. Shields, Jeffrey R. Idle, Philip B. Smith, Katsuhiro Anami, Dickran G. Kazandjian, Emmanuel Hatzakis, Frank J. Gonzalez, Curtis C. Harris, 2014, Cancer Research on p. 3259-3270

The analytical investigation of synthetic street drugs containing cathinone analogs

Amanda M. Leffler, Philip B. Smith, Adriana de Armas, Franklin Lewis Dorman, Jr., 2014, Forensic Science International on p. 50-56

Reversing methanogenesis to capture methane for liquid biofuel precursors

Valerie W.C. Soo, Michael J. McAnulty, Arti Tripathi, Fayin Zhu, Limin Zhang, Emmanuel Hatzakis, Philip B. Smith, Saumya Agrawal, Hadi Nazem-Bokaee, Saratram Gopalakrishnan, Howard M. Salis, James Gregory Ferry, Costas D. Maranas, Andrew David Patterson, Thomas Keith Wood, 2016, Microbial Cell Factories

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet

Naoki Tanaka, Shogo Takahashi, Yuan Zhang, Kristopher W. Krausz, Philip B. Smith, Andrew David Patterson, Frank J. Gonzalez, 2015, Biochimica et Biophysica Acta - Molecular Basis of Disease on p. 1242-1252

Species-specific ant brain manipulation by a specialized fungal parasite

Charissa De Bekker, Lauren E. Quevillon, Philip B. Smith, Kimberly R. Fleming, Debashis Ghosh, Andrew David Patterson, David Peter Hughes, 2014, BMC Evolutionary Biology

Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner

Rachel Tanos, Rushang D. Patel, Iain Alexander Murray, Philip B. Smith, Andrew David Patterson, Gary H. Perdew, 2012, Hepatology on p. 1994-2004

Farnesoid X receptor signaling shapes the gut microbiota and controls hepatic lipid metabolism

Limin Zhang, Cen Xie, Robert G. Nichols, Siu H.J. Chan, Changtao Jiang, Ruixin Hao, Philip B. Smith, Jingwei Cai, Margaret N. Simons, Emmanuel Hatzakis, Costas D. Maranas, Frank J. Gonzalez, Andrew David Patterson, 2016, mSystems

Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice

Limin Zhang, Emmanuel Hatzakis, Robert G. Nichols, Ruixin Hao, Jared Correll, Philip B. Smith, Christopher R. Chiaro, Gary H. Perdew, Andrew David Patterson, 2015, Environmental Science and Technology on p. 8067-8077

Role of the Ah receptor in homeostatic control of fatty acid synthesis in the liver

Rachel Tanos, Iain Alexander Murray, Philip B. Smith, Andrew David Patterson, Gary H. Perdew, 2012, Toxicological Sciences on p. 372-379