Peter Butler

Professor of Bioengineering

Peter Butler

Research Summary

Fundamental molecular mechanisms by which vascular endothelial cells sense the forces from flowing blood and transduce this mechanical information into adjustments of cell and tissue biology.

Huck Affiliations

Links

Publication Tags

Enzymes Membranes Substrates Nanoparticles Molecules Aquaporins Cells Lipids Stiffness Calcium Macrophages Pancreatic Neoplasms Pumps Water Neoplasms Permeability Tumors Engines Encapsulation Selectivity Cracks Glucose Oxidase Exosomes Catalase Bioactivity

Most Recent Papers

Motility of enzyme-powered vesicles

Subhadip Ghosh, Farzad Mohajerani, Seoyoung Son, Darrell Velegol, Peter J. Butler, Ayusman Sen, 2019, Nano Letters on p. 6019-6026

Nonuniform crowding enhances transport

Matthew Collins, Farzad Mohajerani, Subhadip Ghosh, Rajarshi Guha, Tae Hee Lee, Peter J. Butler, Ayusman Sen, Darrell Velegol, 2019, ACS Nano on p. 8946-8956

Mechanobiology of the abluminal glycocalyx

Peter J. Butler, Amit Bhatnagar, 2019, Biorheology on p. 101-112

Achieving high permeability and enhanced selectivity for Angstrom-scale separations using artificial water channel membranes

Yue Xiao Shen, Woochul C. Song, D. Ryan Barden, Tingwei Ren, Chao Lang, Hasin Feroz, Codey B. Henderson, Patrick O. Saboe, Daniel Tsai, Hengjing Yan, Peter J. Butler, Guillermo C. Bazan, William A. Phillip, Robert John Hickey, III, Paul S. Cremer, Harish Vashisth, Manish Kumar, 2018, Nature Communications

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Samuel S. Linton, Thomas Abraham, Jason Liao, Gary A. Clawson, Peter J. Butler, Todd Fox, Mark Kester, Gail L. Matters, 2018, PLoS One

Light-Driven Chloride Transport Kinetics of Halorhodopsin

Hasin Feroz, Bryan Ferlez, Cecile Lefoulon, Tingwei Ren, Carol Sue Baker, John P. Gajewski, Daniel J. Lugar, Sandeep B. Gaudana, Peter J. Butler, Jonas Hühn, Matthias Lamping, Wolfgang J. Parak, Julian M. Hibberd, Cheryl A. Kerfeld, Nicholas Smirnoff, Michael R. Blatt, John H. Golbeck, Manish Kumar, 2018, Biophysical Journal on p. 353-360

Mechanotargeting: Mechanics-dependent cellular uptake of nanoparticles

Qiong Wei, Changjin Huang, Yao Zhang, Tiankai Zhao, Peng Zhao, Peter J. Butler, Sulin Zhang, 2018, Advanced Materials

Substrate-driven chemotactic assembly in an enzyme cascade

Xi Zhao, Henri Palacci, Vinita Yadav, Michelle Marie Spiering, Michael K. Gilson, Peter J. Butler, Henry Hess, Stephen Benkovic, Ayusman Sen, 2018, Nature Chemistry on p. 311-317

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Welley S. Loc, Samuel S. Linton, Zachary R. Wilczynski, Gail Matters, Christopher O. McGovern, Thomas Abraham, Todd Fox, Christopher M. Gigliotti, Xiaomeng Tang, Amra Tabakovic, Jo Ann Martin, Gary Clawson, Jill P. Smith, Peter J. Butler, Mark Kester, James Hansell Adair, 2017, Nanomedicine: Nanotechnology, Biology, and Medicine on p. 2313-2324

β<sub>1</sub>-Integrin-Mediated Adhesion Is Lipid-Bilayer Dependent

Seoyoung Son, George J. Moroney, Peter J. Butler, 2017, Biophysical Journal on p. 1080-1092

Most-Cited Papers

Enzyme molecules as nanomotors

Samudra Sengupta, Krishna K. Dey, Hari S. Muddana, Tristan Tabouillot, Michael E. Ibele, Peter J. Butler, Ayusman Sen, 2013, Journal of the American Chemical Society on p. 1406-1414

Highly permeable artificial water channels that can self-assemble into two-dimensional arrays

Yue Xiao Shen, Wen Si, Mustafa Erbakan, Karl Decker, Rita De Zorzi, Patrick O. Saboe, You Jung Kang, Sheereen Majd, Peter J. Butler, Thomas Walz, Aleksei Aksimentiev, Jun Li Hou, Manish Kumar, David A. Weitz, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 9810-9815

Chemotactic separation of enzymes

Krishna Kanti Dey, Sambeeta Das, Matthew F. Poyton, Samudra Sengupta, Peter J. Butler, Paul S. Cremer, Ayusman Sen, 2014, ACS Nano on p. 11941-11949

Tuning membrane phase separation using nonlipid amphiphiles

Hari S. Muddana, Homer H. Chiang, Peter J. Butler, 2012, Biophysical Journal on p. 489-497

DNA polymerase as a molecular motor and pump

Samudra Sengupta, Michelle Marie Spiering, Krishna K. Dey, Wentao Duan, Debabrata Patra, Peter J. Butler, R. Dean Astumian, Stephen Benkovic, Ayusman Sen, 2014, ACS Nano on p. 2410-2418

Substrate-driven chemotactic assembly in an enzyme cascade

Xi Zhao, Henri Palacci, Vinita Yadav, Michelle Marie Spiering, Michael K. Gilson, Peter J. Butler, Henry Hess, Stephen Benkovic, Ayusman Sen, 2018, Nature Chemistry on p. 311-317

Substrate stiffness regulates cellular uptake of nanoparticles

Changjin Huang, Peter J. Butler, Sheng Tong, Hari S. Muddana, Gang Bao, Sulin Zhang, 2013, Nano Letters on p. 1611-1615

Atomistic simulation of lipid and DiI dynamics in membrane bilayers under tension

Hari S. Muddana, Ramachandra R. Gullapalli, Evangelos Manias, Peter J. Butler, 2011, Physical Chemistry Chemical Physics on p. 1368-1378

Exothermicity Is Not a Necessary Condition for Enhanced Diffusion of Enzymes

Pierre Illien, Xi Zhao, Krishna K. Dey, Peter J. Butler, Ayusman Sen, Ramin Golestanian, 2017, Nano Letters on p. 4415-4420

Achieving high permeability and enhanced selectivity for Angstrom-scale separations using artificial water channel membranes

Yue Xiao Shen, Woochul C. Song, D. Ryan Barden, Tingwei Ren, Chao Lang, Hasin Feroz, Codey B. Henderson, Patrick O. Saboe, Daniel Tsai, Hengjing Yan, Peter J. Butler, Guillermo C. Bazan, William A. Phillip, Robert John Hickey, III, Paul S. Cremer, Harish Vashisth, Manish Kumar, 2018, Nature Communications