Paul Babitzke
Co-Director of the Center for RNA Molecular Biology; Professor of Biochemistry and Molecular Biology
- 0203 Althouse Lab
University Park, PA - pxb28@psu.edu
- 814-865-0002
Huck Institutes Affiliations
Most Recent Papers
Examination of Csr regulatory circuitry using epistasis analysis with RNA-seq (Epi-seq) confirms that CsrD affects gene expression via CsrA, CsrB and CsrC
Anastasia H. Potts, Yuanyuan Leng, Paul Babitzke, Tony Romeo, 2018, Scientific Reports
Global regulation by CsrA and its RNA antagonists
Tony Romeo, Paul Babitzke, 2018, Microbiology spectrum
Glyoxals as in vivo RNA structural probes of guanine base-pairing
David Mitchell, Laura E. Ritchey, Hongmarn Park, Paul Babitzke, Sarah M. Assmann, Philip C. Bevilacqua, 2018, RNA on p. 114-124
Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics
Anastasia H. Potts, Christopher A. Vakulskas, Archana Pannuri, Helen Yakhnin, Paul Babitzke, Tony Romeo, 2017, Nature Communications
Modular organization of the NusA- and NusG-stimulated RNA polymerase pause signal that participates in the Bacillus subtilis trp operon attenuation mechanism
Smarajit Mondal, Alexander V. Yakhnin, Paul Babitzke, 2017, Journal of bacteriology
Noncanonical translation initiation comes of age
Paul Babitzke, Michael O'Connor, 2017, Journal of bacteriology
Translational repression of the RpoS antiadapter IraD by CsrA is mediated via translational coupling to a short upstream open reading frame
Hongmarn Park, Louise C. McGibbon, Anastasia H. Potts, Helen Yakhnin, Tony Romeo, Paul Babitzke, 2017, mBio
Circuitry linking the global Csr- and σ<sup>E</sup>-dependent cell envelope stress response systems
Helen Yakhnin, Robert Aichele, Sarah E. Ades, Tony Romeo, Paul Babitzke, 2017, Journal of Bacteriology
Eliminating blurry bands in gels with a simple cost-effective repair to the gel cassette
Jamie L. Bingaman, Erica A. Frankel, Chelsea M. Hull, Kathleen A. Leamy, Kyle J. Messina, David Mitchell, Hongmarn Park, Laura E. Ritchey, Paul Babitzke, Philip C. Bevilacqua, 2016, RNA on p. 1929-1930
Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins
Christopher A. Vakulskas, Yuanyuan Leng, Hazuki Abe, Takumi Amaki, Akihiro Okayama, Paul Babitzke, Kazushi Suzuki, Tony Romeo, 2016, Nucleic acids research on p. 7896-7910
High-Impact Papers
Circuitry linking the Csr and stringent response global regulatory systems
Adrianne N. Edwards, Laura M. Patterson-Fortin, Christopher A. Vakulskas, Jeffrey W. Mercante, Katarzyna Potrykus, Daniel Vinella, Martha I. Camacho, Joshua A. Fields, Stuart A. Thompson, Dimitris Georgellis, Michael Cashel, Paul Babitzke, Tony Romeo, 2011, Molecular Microbiology on p. 1561-1580
Regulation of bacterial virulence by Csr (Rsm) systems
Christopher A. Vakulskas, Anastasia H. Potts, Babitzke Paul, Brian M.M. Ahmer, Romeo Tony, 2015, Microbiology and Molecular Biology Reviews on p. 193-224
Integration of a complex regulatory cascade involving the SirA/BarA and Csr global regulatory systems that controls expression of the Salmonella SPI-1 and SPI-2 virulence regulons through HilD
Luary C. Martínez, Helen Yakhnin, Martha I. Camacho, Dimitris Georgellis, Paul Babitzke, José L. Puente, Víctor H. Bustamante, 2011, Molecular Microbiology on p. 1637-1656
CsrA activates flhDC expression by protecting flhDC mRNA from RNase E-mediated cleavage
Alexander V. Yakhnin, Carol S. Baker, Christopher A. Vakulskas, Helen Yakhnin, Igor Berezin, Tony Romeo, Paul Babitzke, 2013, Molecular Microbiology on p. 851-866
Molecular Geometry of CsrA (RsmA) Binding to RNA and Its Implications for Regulated Expression
Jeffrey Mercante, Adrianne N. Edwards, Ashok K. Dubey, Paul Babitzke, Tony Romeo, 2009, Journal of Molecular Biology on p. 511-528
A genome-wide analysis of small regulatory RNAs in the human pathogen group a Streptococcus
Nataly Perez, Jeanette Treviño, Zhuyun Liu, Siu Chun Michael Ho, Paul Babitzke, Paul Sumby, 2009, PLoS One
Complex regulation of the global regulatory gene csrA
Helen Yakhnin, Alexander V. Yakhnin, Carol S. Baker, Elena Sineva, Igor Berezin, Tony Romeo, Paul Babitzke, 2011, Molecular Microbiology on p. 689-704
CsrA-FliW interaction governs flagellin homeostasis and a checkpoint on flagellar morphogenesis in Bacillus subtilis
Sampriti Mukherjee, Helen Yakhnin, Dave Kysela, Josh Sokoloski, Paul Babitzke, Daniel B. Kearns, 2011, Molecular Microbiology on p. 447-461
CsrA Represses Translation of sdiA, Which Encodes the N-acylhomoserine-L-lactone receptor of Escherichia coli, by Binding exclusively within the coding region of sdiA mRNA
Helen Yakhnin, Carol S. Baker, Igor Berezin, Michael A. Evangelista, Alisa Rassin, Tony Romeo, Paul Babitzke, 2011, Journal of Bacteriology on p. 6162-6170
Translational repression of NhaR, a novel pathway for multi-tier regulation of biofilm circuitry by CsrA
Archana Pannuri, Helen Yakhnin, Christopher A. Vakulskas, Adrianne N. Edwards, Paul Babitzke, Tony Romeo, 2012, Journal of Bacteriology on p. 79-89