Pamela Giblin
Professor of Immunology
-
105 Henning
University Park, PA - phc7@psu.edu
- 814-863-0128
Research Summary
The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.
Huck Affiliations
Links
Publication Tags
Macrophages Inflammation Liver Diet Receptor Protein Tyrosine Kinases Tissue Obesity Cytokines Heme Ribosomes Mitochondria Heterogeneity Purification Nutrition Ligand Chemical Activation Collagen Ligands Central Nervous System Cells Proteins Protein Health Atherosclerosis TherapeuticsMost Recent Publications
Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C
Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment
Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8<sup>+</sup> T-cell activation
Zhengqi Wang, Tamisha Y. Vaughan, Wandi Zhu, Yuhong Chen, Guoping Fu, Magdalena Medrzycki, Hikaru Nishio, Silvia T. Bunting, Pamela A. Hankey-Giblin, Asma Nusrat, Charles A. Parkos, Demin Wang, Renren Wen, Kevin D. Bunting, 2019, Frontiers in Immunology
Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model
Joselyn Allen, Jingtao Zhang, Michael D. Quickel, Mary Kennett, Andrew D. Patterson, Pamela A. Hankey-Giblin, 2018, Journal of Proteome Research on p. 3268-3280
Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder
Adwitia Dey, Pamela A.Hankey Giblin, 2018, Pharmaceuticals
Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease
Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin, 2018, Frontiers in Immunology
Reduced competitive repopulation capacity of multipotential hematopoietic stem cells in the bone marrow of friend virus-infected Fv2-resistant mice
Michael W. Epperly, Xichen Zhang, Renee Fisher, Wen Hou, Darcy Franicola, Donna Shields, Michael Quickel, Pamela Hankey-Giblin, Hong Wang, Joel S. Greenberger, 2017, In Vivo on p. 313-320
Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation
Joselyn N. Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M. Peters, Pamela A. Hankey-Giblin, 2017, Journal of Visualized Experiments
The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis
Shan Yu, Joselyn N. Allen, Adwitia Dey, Limin Zhang, Gayathri Balandaram, Mary J. Kennett, Mingcan Xia, Na Xiong, Jeffrey M. Peters, Andrew Patterson, Pamela A. Hankey-Giblin, 2016, Journal of Immunology on p. 256-265
Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria
Heather A. Feaga, Michael D. Quickel, Pamela A. Hankey-Giblin, Kenneth C. Keiler, 2016, PLoS Genetics
Ontogeny and polarization of macrophages in inflammation: Blood monocytes versus tissue macrophages
Adwitia Dey, Joselyn Allen, Pamela A. Hankey-Giblin, 2015, Frontiers in Immunology
Most-Cited Papers
Ontogeny and polarization of macrophages in inflammation: Blood monocytes versus tissue macrophages
Adwitia Dey, Joselyn Allen, Pamela A. Hankey-Giblin, 2015, Frontiers in Immunology
Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder
Adwitia Dey, Pamela A.Hankey Giblin, 2018, Pharmaceuticals
Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C
Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment
Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria
Heather A. Feaga, Michael D. Quickel, Pamela A. Hankey-Giblin, Kenneth C. Keiler, 2016, PLoS Genetics
The RON receptor tyrosine kinase: A key regulator of inflammation and cancer progression
Xin Wang, Pamela Hankey Giblin, 2013, Critical Reviews in Immunology on p. 549-574
The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis
Shan Yu, Joselyn N. Allen, Adwitia Dey, Limin Zhang, Gayathri Balandaram, Mary J. Kennett, Mingcan Xia, Na Xiong, Jeffrey M. Peters, Andrew Patterson, Pamela A. Hankey-Giblin, 2016, Journal of Immunology on p. 256-265
Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation
Joselyn N. Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M. Peters, Pamela A. Hankey-Giblin, 2017, Journal of Visualized Experiments
Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease
Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin, 2018, Frontiers in Immunology
Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8<sup>+</sup> T-cell activation
Zhengqi Wang, Tamisha Y. Vaughan, Wandi Zhu, Yuhong Chen, Guoping Fu, Magdalena Medrzycki, Hikaru Nishio, Silvia T. Bunting, Pamela A. Hankey-Giblin, Asma Nusrat, Charles A. Parkos, Demin Wang, Renren Wen, Kevin D. Bunting, 2019, Frontiers in Immunology
Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model
Joselyn Allen, Jingtao Zhang, Michael D. Quickel, Mary Kennett, Andrew D. Patterson, Pamela A. Hankey-Giblin, 2018, Journal of Proteome Research on p. 3268-3280