Pamela Giblin

Professor of Immunology

105 Henning
University Park, PA
phc7@psu.edu
814-863-0128

Bio & Links
Publications

Research Summary

The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Huck Affiliations

Integrative and Biomedical Physiology

Molecular, Cellular, and Integrative Biosciences

Publication Tags

Macrophages Inflammation Liver Receptor Protein Tyrosine Kinases Obesity Heme Tissue Diet Ribosomes Mitochondria Heterogeneity Purification Cytokines Chemical Activation Central Nervous System Cells Ligand Nutrition Ron Protein Protein Health Proteins Atherosclerosis Erythropoiesis Ligands

Most Recent Publications

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment

Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8<sup>+</sup> T-cell activation

Zhengqi Wang, Tamisha Y. Vaughan, Wandi Zhu, Yuhong Chen, Guoping Fu, Magdalena Medrzycki, Hikaru Nishio, Silvia T. Bunting, Pamela A. Hankey-Giblin, Asma Nusrat, Charles A. Parkos, Demin Wang, Renren Wen, Kevin D. Bunting, 2019, Frontiers in Immunology

Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model

Joselyn Allen, Jingtao Zhang, Michael D. Quickel, Mary Kennett, Andrew D. Patterson, Pamela A. Hankey-Giblin, 2018, Journal of Proteome Research on p. 3268-3280

Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder

Adwitia Dey, Pamela A.Hankey Giblin, 2018, Pharmaceuticals

Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease

Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin, 2018, Frontiers in Immunology

Reduced competitive repopulation capacity of multipotential hematopoietic stem cells in the bone marrow of friend virus-infected Fv2-resistant mice

Michael W. Epperly, Xichen Zhang, Renee Fisher, Wen Hou, Darcy Franicola, Donna Shields, Michael Quickel, Pamela Hankey-Giblin, Hong Wang, Joel S. Greenberger, 2017, In Vivo on p. 313-320

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Joselyn N. Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M. Peters, Pamela A. Hankey-Giblin, 2017, Journal of Visualized Experiments

The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis

Shan Yu, Joselyn N. Allen, Adwitia Dey, Limin Zhang, Gayathri Balandaram, Mary J. Kennett, Mingcan Xia, Na Xiong, Jeffrey M. Peters, Andrew Patterson, Pamela A. Hankey-Giblin, 2016, Journal of Immunology on p. 256-265

Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria

Heather A. Feaga, Michael D. Quickel, Pamela A. Hankey-Giblin, Kenneth C. Keiler, 2016, PLoS Genetics

Ontogeny and polarization of macrophages in inflammation: Blood monocytes versus tissue macrophages

Adwitia Dey, Joselyn Allen, Pamela A. Hankey-Giblin, 2015, Frontiers in Immunology

Most-Cited Papers