Pamela Giblin

Professor of Immunology

Pamela Giblin

Research Summary

The role of receptor tyrosine kinases in normal physiology and disease progression; the downstream signals that mediate these responses in vivo and in vitro.

Huck Affiliations

Links

Publication Tags

Macrophages Inflammation Liver Receptor Protein Tyrosine Kinases Obesity Heme Tissue Diet Ribosomes Mitochondria Heterogeneity Purification Cytokines Chemical Activation Central Nervous System Cells Ligand Nutrition Ron Protein Protein Health Proteins Atherosclerosis Erythropoiesis Ligands

Most Recent Papers

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment

Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8<sup>+</sup> T-cell activation

Zhengqi Wang, Tamisha Y. Vaughan, Wandi Zhu, Yuhong Chen, Guoping Fu, Magdalena Medrzycki, Hikaru Nishio, Silvia T. Bunting, Pamela A. Hankey-Giblin, Asma Nusrat, Charles A. Parkos, Demin Wang, Renren Wen, Kevin D. Bunting, 2019, Frontiers in Immunology

Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model

Joselyn Allen, Jingtao Zhang, Michael D. Quickel, Mary Kennett, Andrew D. Patterson, Pamela A. Hankey-Giblin, 2018, Journal of Proteome Research on p. 3268-3280

Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder

Adwitia Dey, Pamela A.Hankey Giblin, 2018, Pharmaceuticals

Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease

Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin, 2018, Frontiers in Immunology

Reduced competitive repopulation capacity of multipotential hematopoietic stem cells in the bone marrow of friend virus-infected Fv2-resistant mice

Michael W. Epperly, Xichen Zhang, Renee Fisher, Wen Hou, Darcy Franicola, Donna Shields, Michael Quickel, Pamela Hankey-Giblin, Hong Wang, Joel S. Greenberger, 2017, In Vivo on p. 313-320

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Joselyn N. Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M. Peters, Pamela A. Hankey-Giblin, 2017, Journal of Visualized Experiments

The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis

Shan Yu, Joselyn N. Allen, Adwitia Dey, Limin Zhang, Gayathri Balandaram, Mary J. Kennett, Mingcan Xia, Na Xiong, Jeffrey M. Peters, Andrew Patterson, Pamela A. Hankey-Giblin, 2016, Journal of Immunology on p. 256-265

Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria

Heather A. Feaga, Michael D. Quickel, Pamela A. Hankey-Giblin, Kenneth C. Keiler, 2016, PLoS Genetics

Ontogeny and polarization of macrophages in inflammation

Adwitia Dey, Joselyn Allen, Pamela A. Hankey-Giblin, 2015, Frontiers in Immunology

Most-Cited Papers

Ontogeny and polarization of macrophages in inflammation

Adwitia Dey, Joselyn Allen, Pamela A. Hankey-Giblin, 2015, Frontiers in Immunology

Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay-Kumar, Pamela Hankey-Giblin, K. Sandeep Prabhu, Robert F. Paulson, 2019, Science's STKE : signal transduction knowledge environment

Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder

Adwitia Dey, Pamela A.Hankey Giblin, 2018, Pharmaceuticals

Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria

Heather A. Feaga, Michael D. Quickel, Pamela A. Hankey-Giblin, Kenneth C. Keiler, 2016, PLoS Genetics

Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by stem cell-derived tyrosine kinase.

Carol R. Gardner, Pamela Hankey, Vladimir Mishin, Mary Francis, Shan Yu, Jeffrey D. Laskin, Debra L. Laskin, 2012, Toxicology and Applied Pharmacology on p. 139-148

The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis

Shan Yu, Joselyn N. Allen, Adwitia Dey, Limin Zhang, Gayathri Balandaram, Mary J. Kennett, Mingcan Xia, Na Xiong, Jeffrey M. Peters, Andrew Patterson, Pamela A. Hankey-Giblin, 2016, Journal of Immunology on p. 256-265

Self-renewal of leukemia stem cells in friend virus-induced erythroleukemia requires proviral insertional activation of spi1 and hedgehog signaling but not mutation of p53

Shailaja Hegde, Pamela Hankey, Robert F. Paulson, 2012, Stem Cells on p. 121-130

The ron receptor tyrosine kinase: a key regulator of inflammation and cancer progression.

Xin Wang, Pamela Hankey Giblin, 2013, Critical Reviews in Immunology on p. 549-574

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Joselyn N. Allen, Adwitia Dey, Ruth Nissly, James Fraser, Shan Yu, Gayathri Balandaram, Jeffrey M. Peters, Pamela A. Hankey-Giblin, 2017, Journal of Visualized Experiments

Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease

Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin, 2018, Frontiers in Immunology