Pak Kin Wong

Professor of Biomedical Engineering, Mechanical Engineering, and Surgery

Pak Kin Wong

Publication Tags

Bacteria Antimicrobial Agent Neoplasms Anti Bacterial Agents Antioxidants Cells Assays Biosensing Techniques Locked Nucleic Acid Wound Healing Testing Cell Movement Infections Nf E2 Related Factor 2 Tanshinone Genes Transducers Resistance Technology Therapeutics Application Proteins Fluorescence Single Cell Analysis In Vitro Techniques

Most Recent Publications

A reconfigurable microfluidic building block platform for high-throughput nonhormonal contraceptive screening

Jyong Huei Lee, Carl van der Linden, Francisco J. Diaz, Pak Kin Wong, 2022, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 2531-2539

Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration

Samuel A. Vilchez Mercedes, Federico Bocci, Mona Ahmed, Ian Eder, Ninghao Zhu, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, Pak Kin Wong, 2022, Frontiers in Molecular Biosciences

Diagnosis of Bloodstream Infections: An Evolution of Technologies towards Accurate and Rapid Identification and Antibiotic Susceptibility Testing

Kristel C. Tjandra, Nikhil Ram-Mohan, Ryuichiro Abe, Marjan M. Hashemi, Jyong Huei Lee, Siew Mei Chin, Manuel A. Roshardt, Joseph C. Liao, Pak Kin Wong, Samuel Yang, 2022, Antibiotics

Optimizing locked nucleic acid modification in double-stranded biosensors for live single cell analysis

Samuel A. Vilchez Mercedes, Ian Eder, Mona Ahmed, Ninghao Zhu, Pak Kin Wong, 2022, The Analyst on p. 722-733

Chemical design of self-propelled Janus droplets

Caleb H. Meredith, Alexander C. Castonguay, Yu Jen Chiu, Allan M. Brooks, Pepijn G. Moerman, Peter Torab, Pak Kin Wong, Ayusman Sen, Darrell Velegol, Lauren D. Zarzar, 2022, Matter on p. 616-633

A transparent ultrasound on-chip platform enables high-throughput cell stimulation and simultaneous high-resolution optical imaging

Haoyang Chen, Ninghao Zhu, Ryan Biskowitz, Jinyun Liu, Cheri Deng, Pak Kin Wong, Sri Rajasekhar Kothapalli, 2022,

Transient nuclear deformation primes epigenetic state and promotes cell reprogramming

Yang Song, Jennifer Soto, Binru Chen, Tyler Hoffman, Weikang Zhao, Ninghao Zhu, Qin Peng, Longwei Liu, Chau Ly, Pak Kin Wong, Yingxiao Wang, Amy C. Rowat, Siavash K. Kurdistani, Song Li, 2022, Nature Materials

Decoding leader cells in collective cancer invasion

Samuel A. Vilchez Mercedes, Federico Bocci, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, Pak Kin Wong, 2021, Nature Reviews Cancer on p. 592-604

A rapid single-cell antimicrobial susceptibility testing workflow for bloodstream infections

Britney Forsyth, Peter Torab, Jyong Huei Lee, Tyler Malcom, Tza Huei Wang, Joseph C. Liao, Samuel Yang, Erik Kvam, Chris Puleo, Pak Kin Wong, 2021, Biosensors

Digital electrical impedance analysis for single bacterium sensing and antimicrobial susceptibility testing

Brian Scherer, Christine Surrette, Hui Li, Peter Torab, Erik Kvam, Craig Galligan, Steven Go, Greg Grossmann, Tyler Hammond, Tammy Johnson, Richard St-Pierre, John R. Nelson, Radislav A. Potyrailo, Tejas Khire, Kuangwen Hsieh, Tza Huei Wang, Pak Kin Wong, Chris M. Puleo, 2021, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 1073-1083

Most-Cited Papers

P62 links autophagy and Nrf2 signaling

Tao Jiang, Bryan Harder, Montserrat Rojo De La Vega, Pak K. Wong, Eli Chapman, Donna D. Zhang, 2015, Free Radical Biology and Medicine on p. 199-204

Advances and challenges in biosensor-based diagnosis of infectious diseases

Mandy Ly Sin, Kathleen E. Mach, Pak Kin Wong, Joseph C. Liao, 2014, Expert Review of Molecular Diagnostics on p. 225-244

Oncogenic KRAS confers chemoresistance by upregulating NRF2

Shasha Tao, Shue Wang, Seyed Javad Moghaddam, Aikseng Ooi, Eli Chapman, Pak K. Wong, Donna D. Zhang, 2014, Cancer Research on p. 7430-7441

Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis

Tongde Wu, Fei Zhao, Beixue Gao, Can Tan, Naoko Yagishita, Toshihiro Nakajima, Pak K. Wong, Eli Chapman, Deyu Fang, Donna D. Zhang, 2014, Genes and Development on p. 708-722

An essential role of NRF2 in diabetic wound healing

Min Long, Montserrat Rojo De La Vega, Qing Wen, Manish Bharara, Tao Jiang, Rui Zhang, Shiwen Zhou, Pak K. Wong, Georg T. Wondrak, Hongting Zheng, Donna D. Zhang, 2016, Diabetes on p. 780-793

Advances in wound-healing assays for probing collective cell migration

Reza Riahi, Yongliang Yang, Donna D. Zhang, Pak Kin Wong, 2012, JALA - Journal of the Association for Laboratory Automation on p. 59-65

Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo

Shasha Tao, Yi Zheng, Alexandria Lau, Melba C. Jaramillo, Binh T. Chau, R. Clark Lantz, Pak K. Wong, Georg T. Wondrak, Donna D. Zhang, 2013, Antioxidants and Redox Signaling on p. 1647-1661

Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration

Reza Riahi, Jian Sun, Shue Wang, Min Long, Donna D. Zhang, Pak Kin Wong, 2015, Nature Communications

Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading

Yi Lu, Jian Gao, Donna D. Zhang, Vincent Gau, Joseph C. Liao, Pak Kin Wong, 2013, Analytical Chemistry on p. 3971-3976

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

Hui Li, Peter Torab, Kathleen E. Mach, Christine Surrette, Matthew R. England, David W. Craft, Neal J. Thomas, Joseph C. Liao, Chris Puleo, Pak Kin Wong, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 10270-10279