Pak Kin Wong

Professor of Biomedical Engineering, Mechanical Engineering, and Surgery

Pak Kin Wong

Publication Tags

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Cells Bacteria Antimicrobial Agent Microfluidics Neoplasms Testing Anti Bacterial Agents Resistance Antioxidants Fluorescence Phenotype Biosensing Techniques Application Blood Epithelial Mesenchymal Transition Locked Nucleic Acid Tanshinone Nf E2 Related Factor 2 Genes Infections Assays Transducers Therapeutics Technology Neurons

Most Recent Publications

Transient nuclear deformation primes epigenetic state and promotes cell reprogramming

Yang Song, Jennifer Soto, Binru Chen, Tyler Hoffman, Weikang Zhao, Ninghao Zhu, Qin Peng, Longwei Liu, Chau Ly, Pak Kin Wong, Yingxiao Wang, Amy C. Rowat, Siavash K. Kurdistani, Song Li, 2022, Nature Materials on p. 1191-1199

Optimizing locked nucleic acid modification in double-stranded biosensors for live single cell analysis

Samuel A. Vilchez Mercedes, Ian Eder, Mona Ahmed, Ninghao Zhu, Pak Kin Wong, 2022, The Analyst on p. 722-733

Diagnosis of Bloodstream Infections: An Evolution of Technologies towards Accurate and Rapid Identification and Antibiotic Susceptibility Testing

Kristel C. Tjandra, Nikhil Ram-Mohan, Ryuichiro Abe, Marjan M. Hashemi, Jyong Huei Lee, Siew Mei Chin, Manuel A. Roshardt, Joseph C. Liao, Pak Wong, Samuel Yang, 2022, Antibiotics on p. 25

A reconfigurable microfluidic building block platform for high-throughput nonhormonal contraceptive screening

Jyong-Huei Lee, Carl Van Der Linden, Francisco Diaz, Pak Kin Wong, 2022, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 2531--2539

Chemical design of self-propelled Janus droplets

Caleb Meredith, Darrell Velegol, Alexander Castonguay, Alexander Castonguay, Yu Chiu, Yu-Jen Chiu, Allan Brooks, Allan Brooks, Pepijn Moerman, Pepijn Moerman, Peter Torab, Pak Kin Wong, Peter Torab, Ayusman Sen, PakKin Wong, Ayusman Sen, Lauren Zarzar, 2022, Matter on p. 616-633

Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration

Samuel A. Vilchez Mercedes, Federico Bocci, Mona Ahmed, Ian Eder, Ninghao Zhu, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, Pak Wong, 2022, Frontiers in Molecular Biosciences on p. 19

A transparent ultrasound on-chip platform enables high-throughput cell stimulation and simultaneous high-resolution optical imaging

Haoyang Chen, Ninghao Zhu, Ryan Biskowitz, Jinyun Liu, Cheri Deng, Pak Kin Wong, Sri Rajasekhar Kothapalli, 2022,

Decoding leader cells in collective cancer invasion

Samuel A. Vilchez Mercedes, Federico Bocci, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, Pak Kin Wong, 2021, Nature Reviews Cancer on p. 592-604

A rapid single-cell antimicrobial susceptibility testing workflow for bloodstream infections

Britney Forsyth, Peter Torab, Jyong Huei Lee, Tyler Malcom, Tza Huei Wang, Joseph C. Liao, Samuel Yang, Erik Kvam, Chris Puleo, Pak Kin Wong, 2021, Biosensors

Digital electrical impedance analysis for single bacterium sensing and antimicrobial susceptibility testing

Brian Scherer, Christine Surrette, Hui Li, Peter Torab, Erik Kvam, Craig Galligan, Steven Go, Greg Grossmann, Tyler Hammond, Tammy Johnson, Richard St-Pierre, John R. Nelson, Radislav A. Potyrailo, Tejas Khire, Kuangwen Hsieh, Tza Huei Wang, Pak Kin Wong, Chris M. Puleo, 2021, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 1073-1083

Most-Cited Papers

P62 links autophagy and Nrf2 signaling

Tao Jiang, Bryan Harder, Montserrat Rojo De La Vega, Pak K. Wong, Eli Chapman, Donna D. Zhang, 2015, Free Radical Biology and Medicine on p. 199-204

Advances and challenges in biosensor-based diagnosis of infectious diseases

Mandy Ly Sin, Kathleen E. Mach, Pak Kin Wong, Joseph C. Liao, 2014, Expert Review of Molecular Diagnostics on p. 225-244

Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis

Tongde Wu, Fei Zhao, Beixue Gao, Can Tan, Naoko Yagishita, Toshihiro Nakajima, Pak K. Wong, Eli Chapman, Deyu Fang, Donna D. Zhang, 2014, Genes and Development on p. 708-722

Oncogenic KRAS confers chemoresistance by upregulating NRF2

Shasha Tao, Shue Wang, Seyed Javad Moghaddam, Aikseng Ooi, Eli Chapman, Pak K. Wong, Donna D. Zhang, 2014, Cancer Research on p. 7430-7441

An essential role of NRF2 in diabetic wound healing

Min Long, Montserrat Rojo De La Vega, Qing Wen, Manish Bharara, Tao Jiang, Rui Zhang, Shiwen Zhou, Pak K. Wong, Georg T. Wondrak, Hongting Zheng, Donna D. Zhang, 2016, Diabetes on p. 780-793

Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo

Shasha Tao, Yi Zheng, Alexandria Lau, Melba C. Jaramillo, Binh T. Chau, R. Clark Lantz, Pak K. Wong, Georg T. Wondrak, Donna D. Zhang, 2013, Antioxidants and Redox Signaling on p. 1647-1661

Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration

Reza Riahi, Jian Sun, Shue Wang, Min Long, Donna D. Zhang, Pak Kin Wong, 2015, Nature Communications

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

Hui Li, Peter Torab, Kathleen E. Mach, Christine Surrette, Matthew R. England, David W. Craft, Neal J. Thomas, Joseph C. Liao, Chris Puleo, Pak Kin Wong, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 10270-10279

NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype

Federico Bocci, Satyendra C. Tripathi, Samuel A. Vilchez Mercedes, Jason T. George, Julian P. Casabar, Pak Kin Wong, Samir M. Hanash, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, 2019, Integrative Biology (United Kingdom) on p. 251-263

Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading

Yi Lu, Jian Gao, Donna D. Zhang, Vincent Gau, Joseph C. Liao, Pak Kin Wong, 2013, Analytical Chemistry on p. 3971-3976