Pak Kin Wong

Professor of Biomedical Engineering, Mechanical Engineering, and Surgery

Pak Kin Wong

Huck Affiliations

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Most Recent Publications

Precision single cell analysis to characterize host dependent antimicrobial response heterogeneity in physiological medium

Ryuichiro Abe, Jyong Huei Lee, Siew Mei Chin, Nikhil Ram-Mohan, Kristel C. Tjandra, April M. Bobenchik, Kathleen E. Mach, Joseph C. Liao, Pak Kin Wong, Samuel Yang, 2025, Lab on a Chip - Miniaturisation for Chemistry and Biology on p. 714-728

Nano-Biosensors for mRNA-Based Cell Sorting Using Intracellular Markers at the Early Stage of Cell Reprogramming

Yang Song, Jennifer Soto, Xiao Lin, Tyler Hoffman, Erin Hu, Ninghao Zhu, Jana Zarubova, Yifan Wu, Jing Tian, Pak Kin Wong, Song Li, 2025, Advanced Functional Materials

Growth independent morphometric machine learning workflow for single-cell antimicrobial susceptibility testing of Klebsiella pneumoniae to meropenem

Kristel Tjandra, Nikhil Ram-Mohan, Manuel Roshardt, Elizabeth Zudock, Zhaoman Qu, Kathlenn Mach, Okyaz Eminaga, Joseph Liao, Samuel Yang, Pak Wong, 2024, Frontiers in Imaging

Rapid Microbial Profiling through Multimodal Biosensors for Transversal Analysis

Jyong Huei Lee, Siew Mei Chin, Dennis C. Chan, Joseph C. Liao, Samuel Yang, Nanying Zhang, Pak Kin Wong, 2024, Analytical Chemistry

Translating microbiota analysis for clinical applications

Jyong-Huei Lee, Siew Mei Chin, Kathleen Mach, April Bobenchik, Jospeh Liao, Samuel Yang, Pak Wong, 2024, Nature Reviews Bioengineering on p. 284-286

Single-cell pathogen diagnostics for combating antibiotic resistance

Hui Li, Kuangwen Hsieh, Pak Kin Wong, Kathleen E. Mach, Joseph C. Liao, Tza Huei Wang, 2023, Nature Reviews Methods Primers

A sticky-end probe biosensor for homogeneous detection of transcription factor binding activity

Joao Paulo Pera Mendes, Ninghao Zhu, Pak Kin Wong, 2023, SLAS Technology on p. 345-350

Long noncoding RNA MALAT1 is dynamically regulated in leader cells during collective cancer invasion

Ninghao Zhu, Mona Ahmed, Yanlin Li, Joseph C. Liao, Pak Kin Wong, 2023, Proceedings of the National Academy of Sciences of the United States of America

Transient nuclear deformation primes epigenetic state and promotes cell reprogramming

Yang Song, Jennifer Soto, Binru Chen, Tyler Hoffman, Weikang Zhao, Ninghao Zhu, Qin Peng, Longwei Liu, Chau Ly, Pak Kin Wong, Yingxiao Wang, Amy C. Rowat, Siavash K. Kurdistani, Song Li, 2022, Nature Materials on p. 1191-1199

Optimizing locked nucleic acid modification in double-stranded biosensors for live single cell analysis

Samuel A. Vilchez Mercedes, Ian Eder, Mona Ahmed, Ninghao Zhu, Pak Kin Wong, 2022, The Analyst on p. 722-733

Most-Cited Papers

P62 links autophagy and Nrf2 signaling

Tao Jiang, Bryan Harder, Montserrat Rojo De La Vega, Pak K. Wong, Eli Chapman, Donna D. Zhang, 2015, Free Radical Biology and Medicine on p. 199-204

An essential role of NRF2 in diabetic wound healing

Min Long, Montserrat Rojo De La Vega, Qing Wen, Manish Bharara, Tao Jiang, Rui Zhang, Shiwen Zhou, Pak K. Wong, Georg T. Wondrak, Hongting Zheng, Donna D. Zhang, 2016, Diabetes on p. 780-793

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

Hui Li, Peter Torab, Kathleen E. Mach, Christine Surrette, Matthew R. England, David W. Craft, Neal J. Thomas, Joseph C. Liao, Chris Puleo, Pak Kin Wong, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 10270-10279

Viscoelastic solid-repellent coatings for extreme water saving and global sanitation

Jing Wang, Lin Wang, Nan Sun, Nan Sun, Ross Tierney, Ross Tierney, Hui Li, Hui Li, Margo Corsetti, Margo Corsetti, Leon Williams, Pak Kin Wong, Leon Williams, Pak Kin Wong, Tak Sing Wong, 2019, Nature Sustainability on p. 1097-1105

NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype

Federico Bocci, Satyendra C. Tripathi, Samuel A. Vilchez Mercedes, Jason T. George, Julian P. Casabar, Pak Kin Wong, Samir M. Hanash, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, 2019, Integrative Biology (United Kingdom) on p. 251-263

Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration

Reza Riahi, Jian Sun, Shue Wang, Min Long, Donna D. Zhang, Pak Kin Wong, 2015, Nature Communications

Decoding leader cells in collective cancer invasion

Samuel A. Vilchez Mercedes, Federico Bocci, Herbert Levine, José N. Onuchic, Mohit Kumar Jolly, Pak Kin Wong, 2021, Nature Reviews Cancer on p. 592-604

Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy?

Tongde Wu, Bryan G. Harder, Pak K. Wong, Julie E. Lang, Donna D. Zhang, 2015, Molecular Carcinogenesis on p. 1494-1502

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality

Christopher T. Pappas, Rachel M. Mayfield, Christine Henderson, Nima Jamilpour, Cathleen Cover, Zachary Hernandez, Kirk R. Hutchinson, Miensheng Chu, Ki Hwan Nam, Jose M. Valdez, Pak Kin Wong, Henk L. Granzier, Carol C. Gregorio, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 13573-13578

A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response

Tao Shen, Tao Jiang, Min Long, Jun Chen, Dong Mei Ren, Pak Kin Wong, Eli Chapman, Bo Zhou, Donna D. Zhang, 2015, Antioxidants and Redox Signaling on p. 651-664