Orfeu Buxton

Professor of Biobehavioral Health

Orfeu Buxton

Research Summary

The causes of chronic sleep deficiency in the workplace, home, and society; the health consequences of chronic sleep deficiency, especially cardiometabolic outcomes, and the physiologic and social mechanisms by which these outcomes arise. Successful aging is a central focus of this work. Ongoing interdisciplinary human studies involve sleep loss, aging, and insomnia, as well as health disparities.

Huck Affiliations

Links

Publication Tags

Sleep Joints Consensus Medicine Research Health Education Glucose Wrist Child Depression Interaction C Reactive Protein Actigraphy European Continental Ancestry Group Eating Sensitivity And Specificity Asian Americans Mexico Polysomnography Noise Politics Sleep Initiation And Maintenance Disorders Body Mass Index Therapeutics

Most Recent Papers

Insomnia Symptoms Burden and Prescribed Sleep Medication Use Predict Fall Risk in Older Adults

Tuo-Yu Chen, S Lee, Orfeu Buxton, Sleep

A randomized trial to decrease risk for diabetes among Cambodian Americans with depression

Julie Wagner, Angela Bermudez-Millan, Thomas Buckley, Orfeu M. Buxton, Richard Feinn, Sengly Kong, Theanvy Kuoch, Nicole G. Nahmod, Mary Scully, 2021, Contemporary Clinical Trials

Reduced coupling between cerebrospinal fluid flow and global brain activity is linked to Alzheimer disease–related pathology

Feng Han, Jing Chen, Aaron Belkin-Rosen, Yameng Gu, Liying Luo, Orfeu M. Buxton, Xiao Liu, 2021, PLoS Biology

Social disconnection and metabolic syndrome score among Cambodian Americans with depression

S. Megan Berthold, Angela Bermudez-Millan, Thomas Buckley, Orfeu M. Buxton, Richard Feinn, Sengly Kong, Theanvy Kuoch, Mary Scully, Kagnica Seng, Julie Wagner, 2021, Diabetes Research and Clinical Practice

Nightly sleep-wake concordance and daily marital interactions

Heather E. Gunn, Soomi Lee, Kenda R. Eberhardt, Orfeu M. Buxton, Wendy M. Troxel, 2021, Sleep Health on p. 266-272

Opposite educational gradients in sleep duration between Black and White adults, 2004-2018

Liying Luo, Orfeu M. Buxton, Alyssa A. Gamaldo, David M. Almeida, Qian Xiao, 2021, Sleep Health on p. 3-9

Patterns of Eating Associated with Sleep Characteristics

Sadia B. Ghani, Marcos E. Delgadillo, Karla Granados, Ashley C. Okuagu, Chloe C.A. Wills, Pamela Alfonso-Miller, Orfeu M. Buxton, Sanjay R. Patel, John Ruiz, Sairam Parthasarathy, Patricia L. Haynes, Patricia Molina, Azizi Seixas, Girardin Jean-Louis, Michael A. Grandner, 2021, Behavioral Sleep Medicine

SNAP participation moderates the association between household food insecurity and HbA1c among Cambodian Americans with depression

Angela Bermúdez-Millán, Richard Feinn, Chelsey Hahn, Shanjida A. Jui, S. Megan Berthold, Thomas Buckley, Orfeu Buxton, Sengly Kong, Theanvy Kuoch, Mary Scully, Julie Wagner, 2021, Ethnicity and Health

Cumulative effects of sleep quality on risk for incident mild cognitive impairment (MCI): Results from the Einstein Aging Study (EAS) cohort. Alzheimer's Dement.

Carol Derby, Cuiling Wang, Mindy Katz, Richard Lipton, Orfeu Buxton, 2020, Alzheimer's Dement

Sleep duration and affective reactivity to stressors and positive events in daily life.

N Sin, J Wen, P Klaiber, Orfeu Buxton, D Almeida, 2020, Health Psychology on p. 1078-1088

Most-Cited Papers

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

Orfeu M. Buxton, Sean W. Cain, Shawn P. O'Connor, James H. Porter, Jeanne F. Duffy, Wei Wang, Charles A. Czeisler, Steven A. Shea, 2012, Science Translational Medicine

Recommended amount of sleep for a healthy adult: A joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Sleep on p. 843-844

Measuring sleep

Miguel Marino, Yi Li, Michael N. Rueschman, J. W. Winkelman, J. M. Ellenbogen, J. M. Solet, Hilary Dulin, Lisa F. Berkman, Orfeu M. Buxton, 2013, Sleep on p. 1747-1755

Joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: Methodology and discussion

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Sleep on p. 1161-1183

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

Christopher J. Morris, Jessica N. Yang, Joanna I. Garcia, Samantha Myers, Isadora Bozzi, Wei Wang, Orfeu M. Buxton, Steven A. Shea, Frank A.J.L. Scheer, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. E2225-E2234

Recommended amount of sleep for a healthy adult: A joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Journal of Clinical Sleep Medicine on p. 591-592

Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Journal of Clinical Sleep Medicine on p. 931-952

Sleep disruption due to hospital noises

Orfeu M. Buxton, Jeffrey M. Ellenbogen, Wei Wang, Andy Carballeira, Shawn O'Connor, Dan Cooper, Ankit J. Gordhandas, Scott M. McKinney, Jo M. Solet, 2012, Annals of Internal Medicine on p. 170-179

Sleep in the modern family: Protective family routines for child and adolescent sleep

Orfeu M. Buxton, Anne-Marie Chang, James C. Spilsbury, Taylor Bos, Helene Emsellem, Kristen L. Knutson, 2015, Sleep Health on p. 15-27

Extreme sleep durations and increased C-reactive protein

Michael A. Grandner, Orfeu M. Buxton, Nicholas Jackson, Megan Sands-Lincoln, Abhishek Pandey, Girardin Jean-Louis, 2013, Sleep on p. 769-779

News Articles Featuring Orfeu Buxton

Coupled brain activity, cerebrospinal fluid flow could indicate Alzheimer's risk

Penn State researchers may have discovered a potential marker to clinically evaluate patients’ risk for Alzheimer’s disease through non-invasive imaging tests, according to a study published in PLOS Biology. The finding may have implications for diagnosis and treatment of the disease that results in significant cognitive decline, the researchers said.

Getting more of this could improve your happiness immediately

Each person’s time on this planet can be likened to a rollercoaster ride, filled with highs and lows. No one’s life is 100% perfect and great all the time, but it’s those bad times that help us appreciate and savor the good moments.

Our sleep is linked to how we process coronavirus dread

Zyma Islam noticed her sleep began to change soon after the lockdown began. Islam is in Dhaka, Bangladesh, which has been under a strict lockdown for over three weeks. All forms of public transport are suspended. That means scores of daily wage earners—domestic helpers, rickshaw pullers, construction workers, and garment workers—have lost wages, and are now battling hunger.

You Can Generate Happiness By Visiting These Natural Destinations

Heartbroken and depressed, my immune system took a dive. Then my doctor gave me a surprise suggestion.

Sleepy and Hungry? Short Sleep May Contribute to Weight Gain

Not getting enough sleep, or getting low-quality sleep, leaves most people feeling poorly the next day. It’s common knowledge that a good night’s sleep is important for maintaining mental focus, peak athletic performance, and emotional resilience. But the effects of sleep, or the lack thereof, reach beyond cognition.

Just four nights of bad sleep can make you gain weight, study claims

Just four nights of poor sleep can make you put on weight, a new study has revealed. Sleep disruption has been known to be have harmful effects on metabolism for some time.

Here’s What Getting Less Than 7 Hours of Sleep a Night Can Do to You

We’re not getting enough sleep — and that’s having a significant impact on our day-to-day and long-term health.

Sleep deprivation may lead to slower metabolism, weight gain

Restricting sleep for just several days alters how we metabolize fats and changes how satisfied we are by a meal, according to new research conducted at Penn State and published in the Journal of Lipid Research.

Sleep Loss Could Affect How Your Body Handles Fat

In a new study, researchers found that just a few days of sleep deprivation can make people feel less full after eating and metabolize the fat in food differently. This finding adds to the mounting evidence about just how harmful lack of sleep can be.

Lack of sleep affects fat metabolism

We're all a little short on sleep during the work week. A new study adds to the mounting evidence about just how harmful lack of sleep can be. In the Journal of Lipid Research, researchers at Pennsylvania State University report that just a few days of sleep deprivation can make participants feel less full after eating and metabolize the fat in food differently.