Orfeu Buxton

Elizabeth Fenton Susman Professor of Biobehavioral Health

Orfeu Buxton

Research Summary

The causes of chronic sleep deficiency in the workplace, home, and society; the health consequences of chronic sleep deficiency, especially cardiometabolic outcomes, and the physiologic and social mechanisms by which these outcomes arise. Successful aging is a central focus of this work. Ongoing interdisciplinary human studies involve sleep loss, aging, and insomnia, as well as health disparities.

Huck Affiliations

Links

Publication Tags

Sleep Medicine Joints Consensus Research Health Workplace Brain Asian Americans Alzheimer Disease Cerebrospinal Fluid Depression Glucose Occupational Groups Metabolic Syndrome Shift Worker Child Noise C Reactive Protein Clearance Polysomnography Systematic Reviews Sensitivity And Specificity Occupational Health Adolescent

Most Recent Papers

Insomnia Symptoms Burden and Prescribed Sleep Medication Use Predict Fall Risk in Older Adults

Tuo-Yu Chen, S Lee, Orfeu Buxton, Sleep

Neighborhood Disadvantage Is Associated with Lower Quality Sleep and More Variability in Sleep Duration among Urban Adolescents

Nicole G. Nahmod, Lindsay Master, Heather F. McClintock, Lauren Hale, Orfeu M. Buxton, 2022, Bulletin of the New York Academy of Medicine

Too jittery to sleep? Temporal associations of actigraphic sleep and caffeine in adolescents

Gina Marie Mathew, David A. Reichenberger, Lindsay Master, Orfeu M. Buxton, Anne Marie Chang, Lauren Hale, 2022, Nutrients

Interindividual differences in attentional vulnerability moderate cognitive performance during sleep restriction and subsequent recovery in healthy young men

Gina Marie Mathew, Stephen M. Strayer, Kelly M. Ness, Margeaux M. Schade, Nicole G. Nahmod, Orfeu M. Buxton, Anne Marie Chang, 2021, Scientific Reports

Emotional Vulnerability to Short Sleep Predicts Increases in Chronic Health Conditions across 8 Years

Nancy L. Sin, Jonathan Rush, Orfeu M. Buxton, David M. Almeida, 2021, Annals of Behavioral Medicine on p. 1231-1240

A Systematic Review of Workplace-Based Employee Health Interventions and Their Impact on Sleep Duration Among Shift Workers

Rebecca Robbins, Phoenix Underwood, Chandra L. Jackson, Giradin Jean-Louis, Shreya Madhavaram, Shiana Kuriakose, Dorice Vieira, Orfeu M. Buxton, 2021, Workplace Health and Safety on p. 525-539

Chronic Sleep Restriction While Minimizing Circadian Disruption Does Not Adversely Affect Glucose Tolerance

Robin K. Yuan, Kirsi Marja Zitting, Jeanne F. Duffy, Nina Vujovic, Wei Wang, Stuart F. Quan, Elizabeth B. Klerman, Frank A.J.L. Scheer, Orfeu M. Buxton, Jonathan S. Williams, Charles A. Czeisler, 2021, Frontiers in Physiology

A randomized trial to decrease risk for diabetes among Cambodian Americans with depression

Julie Wagner, Angela Bermudez-Millan, Thomas Buckley, Orfeu M. Buxton, Richard Feinn, Sengly Kong, Theanvy Kuoch, Nicole G. Nahmod, Mary Scully, 2021, Contemporary Clinical Trials

Reduced coupling between cerebrospinal fluid flow and global brain activity is linked to Alzheimer disease–related pathology

Feng Han, Jing Chen, Aaron Belkin-Rosen, Yameng Gu, Liying Luo, Orfeu M. Buxton, Xiao Liu, 2021, PLoS Biology

Social disconnection and metabolic syndrome score among Cambodian Americans with depression

S. Megan Berthold, Angela Bermudez-Millan, Thomas Buckley, Orfeu M. Buxton, Richard Feinn, Sengly Kong, Theanvy Kuoch, Mary Scully, Kagnica Seng, Julie Wagner, 2021, Diabetes Research and Clinical Practice

Most-Cited Papers

Recommended amount of sleep for a healthy adult: A joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Sleep on p. 843-844

Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption

Orfeu M. Buxton, Sean W. Cain, Shawn P. O'Connor, James H. Porter, Jeanne F. Duffy, Wei Wang, Charles A. Czeisler, Steven A. Shea, 2012, Science Translational Medicine

Measuring sleep

Miguel Marino, Yi Li, Michael N. Rueschman, J. W. Winkelman, J. M. Ellenbogen, J. M. Solet, Hilary Dulin, Lisa F. Berkman, Orfeu M. Buxton, 2013, Sleep on p. 1747-1755

Joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: Methodology and discussion

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Sleep on p. 1161-1183

Recommended amount of sleep for a healthy adult: A joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Journal of Clinical Sleep Medicine on p. 591-592

Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans

Christopher J. Morris, Jessica N. Yang, Joanna I. Garcia, Samantha Myers, Isadora Bozzi, Wei Wang, Orfeu M. Buxton, Steven A. Shea, Frank A.J.L. Scheer, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. E2225-E2234

Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult

Nathaniel F. Watson, M. Safwan Badr, Gregory Belenky, Donald L. Bliwise, Orfeu M. Buxton, Daniel Buysse, David F. Dinges, James Gangwisch, Michael A. Grandner, Clete Kushida, Raman K. Malhotra, Jennifer L. Martin, Sanjay R. Patel, Stuart F. Quan, Esra Tasali, Michael Twery, Janet B. Croft, Elise Maher, Jerome A. Barrett, Sherene M. Thomas, Jonathan L. Heald, 2015, Journal of Clinical Sleep Medicine on p. 931-952

Sleep in the modern family: Protective family routines for child and adolescent sleep

Orfeu M. Buxton, Anne Marie Chang, James C. Spilsbury, Taylor Bos, Helene Emsellem, Kristen L. Knutson, 2015, Sleep Health on p. 15-27

Sleep disruption due to hospital noises

Orfeu M. Buxton, Jeffrey M. Ellenbogen, Wei Wang, Andy Carballeira, Shawn O'Connor, Dan Cooper, Ankit J. Gordhandas, Scott M. McKinney, Jo M. Solet, 2012, Annals of Internal Medicine on p. 170-179

Extreme sleep durations and increased C-reactive protein

Michael A. Grandner, Orfeu M. Buxton, Nicholas Jackson, Megan Sands-Lincoln, Abhishek Pandey, Girardin Jean-Louis, 2013, Sleep on p. 769-779

News Articles Featuring Orfeu Buxton

Coupled brain activity, cerebrospinal fluid flow could indicate Alzheimer's risk

Penn State researchers may have discovered a potential marker to clinically evaluate patients’ risk for Alzheimer’s disease through non-invasive imaging tests, according to a study published in PLOS Biology. The finding may have implications for diagnosis and treatment of the disease that results in significant cognitive decline, the researchers said.

Getting more of this could improve your happiness immediately

Each person’s time on this planet can be likened to a rollercoaster ride, filled with highs and lows. No one’s life is 100% perfect and great all the time, but it’s those bad times that help us appreciate and savor the good moments.

Our sleep is linked to how we process coronavirus dread

Zyma Islam noticed her sleep began to change soon after the lockdown began. Islam is in Dhaka, Bangladesh, which has been under a strict lockdown for over three weeks. All forms of public transport are suspended. That means scores of daily wage earners—domestic helpers, rickshaw pullers, construction workers, and garment workers—have lost wages, and are now battling hunger.

You Can Generate Happiness By Visiting These Natural Destinations

Heartbroken and depressed, my immune system took a dive. Then my doctor gave me a surprise suggestion.

Sleepy and Hungry? Short Sleep May Contribute to Weight Gain

Not getting enough sleep, or getting low-quality sleep, leaves most people feeling poorly the next day. It’s common knowledge that a good night’s sleep is important for maintaining mental focus, peak athletic performance, and emotional resilience. But the effects of sleep, or the lack thereof, reach beyond cognition.

Just four nights of bad sleep can make you gain weight, study claims

Just four nights of poor sleep can make you put on weight, a new study has revealed. Sleep disruption has been known to be have harmful effects on metabolism for some time.

Here’s What Getting Less Than 7 Hours of Sleep a Night Can Do to You

We’re not getting enough sleep — and that’s having a significant impact on our day-to-day and long-term health.

Sleep deprivation may lead to slower metabolism, weight gain

Restricting sleep for just several days alters how we metabolize fats and changes how satisfied we are by a meal, according to new research conducted at Penn State and published in the Journal of Lipid Research.

Sleep Loss Could Affect How Your Body Handles Fat

In a new study, researchers found that just a few days of sleep deprivation can make people feel less full after eating and metabolize the fat in food differently. This finding adds to the mounting evidence about just how harmful lack of sleep can be.

Lack of sleep affects fat metabolism

We're all a little short on sleep during the work week. A new study adds to the mounting evidence about just how harmful lack of sleep can be. In the Journal of Lipid Research, researchers at Pennsylvania State University report that just a few days of sleep deprivation can make participants feel less full after eating and metabolize the fat in food differently.