Neil Christensen

Professor of Pathology and Microbiology and Immunology

Neil Christensen

Publication Tags

Antibodies Viruses Infection Vaccines Rabbits Papillomaviridae Neutralizing Antibodies Capsid Infections Epitopes Genotype Proteins Skin Papillomavirus Infections Neoplasms Monoclonal Antibodies Virus Like Particle Vaccines Capsid Proteins Human Herpesvirus 4 Genome Mice Animal Models Animals T Lymphocytes Dibenzo(A,L)Pyrene

Most Recent Papers

High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility

Daniel J. Goetschius, Samantha R. Hartmann, Suriyasri Subramanian, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein, 2021, Scientific Reports

Cryo em analysis reveals inherent flexibility of authentic murine papillomavirus capsids

Samantha R. Hartmann, Daniel J. Goetschius, Jiafen Hu, Joshua J. Graff, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein, 2021, Viruses

Monoclonal antibodies to s and n sars-cov-2 proteins as probes to assess structural and antigenic properties of coronaviruses

Rinki Kumar, Neil D. Christensen, Rebecca J. Kaddis Maldonado, Maria C. Bewley, Alexandria Ostman, Malgorzata Sudol, Eunice C. Chen, Natalie W. Buchkovich, Abhinay Gontu, Meera Surendran Nair, Ruth H. Nissly, Allen M. Minns, Vivek Kapur, Randall Rossi, Suresh V. Kuchipudi, Scott E. Lindner, Leslie J. Parent, John M. Flanagan, Nicholas J. Buchkovich, 2021, Viruses

Mouse papillomavirus l1 and l2 are dispensable for viral infection and persistence at both cutaneous and mucosal tissues

Sarah Brendle, Jingwei J. Li, Nancy M. Cladel, Debra A. Shearer, Lynn R. Budgeon, Karla K. Balogh, Hannah Atkins, Marina Costa-Fujishima, Paul Lopez, Neil D. Christensen, John Doorbar, Thomas T. Murooka, Jiafen Hu, 2021, Viruses

Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

Vivien Béziat, Franck Rapaport, Jiafen Hu, Matthias Titeux, Mathilde Bonnet des Claustres, Mathieu Bourgey, Heather Griffin, Élise Bandet, Cindy S. Ma, Roya Sherkat, Hassan Rokni-Zadeh, David M. Louis, Majid Changi-Ashtiani, Ottavia M. Delmonte, Toshiaki Fukushima, Tanwir Habib, Andrea Guennoun, Taushif Khan, Noemi Bender, Mahbuba Rahman, Frédégonde About, Rui Yang, Geetha Rao, Claire Rouzaud, Jingwei Li, Debra Shearer, Karla Balogh, Fatima Al Ali, Manar Ata, Soroosh Dabiri, Mana Momenilandi, Justine Nammour, Marie Alexandra Alyanakian, Marianne Leruez-Ville, David Guenat, Marie Materna, Léa Marcot, Natasha Vladikine, Christine Soret, Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Jouni Uitto, Émilie Catherinot, Shadi Sadat Navabi, Mohammed Zarhrate, David T. Woodley, Mohamed Jeljeli, Thomas Abraham, Serkan Belkaya, Lazaro Lorenzo, Jérémie Rosain, Mousa Bayat, Fanny Lanternier, Olivier Lortholary, Faramarz Zakavi, Philippe Gros, Gérard Orth, Laurent Abel, Jean Luc Prétet, Sylvie Fraitag, Emmanuelle Jouanguy, Mark M. Davis, Stuart G. Tangye, Luigi D. Notarangelo, Nico Marr, Tim Waterboer, David Langlais, John Doorbar, Alain Hovnanian, Neil Christensen, Xavier Bossuyt, Mohammad Shahrooei, Jean Laurent Casanova, 2021, Cell on p. 3812-3828.e30

Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research

Jie Xu, Jifeng Zhang, Dongshan Yang, Jun Song, Brooke Pallas, Chen Zhang, Jiafen Hu, Xuwen Peng, Neil D. Christensen, Renzhi Han, Y. Eugene Chen, 2021, Frontiers in Genetics

The environmental pollutant and tobacco smoke constituent dibenzo[def,p]chrysene is a co-factor for malignant progression of mouse oral papillomavirus infections

Neil D. Christensen, Kun Ming Chen, Jiafen Hu, Douglas B. Stairs, Yuan Wan Sun, Cesar Aliaga, Karla K. Balogh, Hannah Atkins, Debra Shearer, Jingwei Li, Sarah A. Brendle, Krishne Gowda, Shantu Amin, Vonn Walter, Raphael Viscidi, Karam El-Bayoumy, 2021, Chemico-Biological Interactions

Comprehensive Assessment of the Antigenic Impact of Human Papillomavirus Lineage Variation on Recognition by Neutralizing Monoclonal Antibodies Raised against Lineage A Major Capsid Proteins of Vaccine-Related Genotypes

Anna Godi, Dolcibella Boampong, Busayo Elegunde, Kavita Panwar, Maxime Fleury, Shaowei Li, Qinjian Zhao, Ningshao Xia, Neil D. Christensen, Simon Beddows, 2020, Journal of Virology

Antibody-Mediated Immune Subset Depletion Modulates the Immune Response in a Rabbit (Oryctolagus cuniculus) Model of Epstein-Barr Virus Infection

Andrea J. Osborne, Hannah M. Atkins, Karla K. Balogh, Sarah A. Brendle, Debra A. Shearer, Jiafen Hu, Clare E. Sample, Neil D. Christensen, 2020, Comparative Medicine on p. 312-322

Antibody escape by polyomavirus capsid mutation facilitates neurovirulence

Matthew D. Lauver, Daniel J. Goetschius, Colleen S. Netherby-Winslow, Katelyn N. Ayers, Ge Jin, Daniel G. Haas, Elizabeth L. Frost, Sung Hyun Cho, Carol M. Bator, Stephanie M. Bywaters, Neil D. Christensen, Susan L. Hafenstein, Aron E. Lukacher, 2020, eLife on p. 1-68

Most-Cited Papers

Efficient replication of Epstein-Barr virus in stratified epithelium in vitro

Rachel M. Temple, Junjia Zhu, Lynn Budgeon, Neil David Christensen, Craig Meyers, Clare E. Sample, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 16544-16549

The wide utility of rabbits as models of human diseases

Pedro J. Esteves, Joana Abrantes, Hanna Mari Baldauf, Lbachir BenMohamed, Yuxing Chen, Neil Christensen, Javier González-Gallego, Lorenzo Giacani, Jiafen Hu, Gilla Kaplan, Oliver T. Keppler, Katherine L. Knight, Xiang Peng Kong, Dennis K. Lanning, Jacques Le Pendu, Ana Lemos De Matos, Jia Liu, Shuying Liu, Ana M. Lopes, Shan Lu, Sheila Lukehart, Yukari C. Manabe, Fabiana Neves, Grant McFadden, Ruimin Pan, Xuwen Peng, Patricia de Sousa-Pereira, Ana Pinheiro, Masmudur Rahman, Natalie Ruvoën-Clouet, Selvakumar Subbian, Maria Jesús Tuñón, Wessel van der Loo, Michael Vaine, Laura E. Via, Shixia Wang, Rose Mage, 2018, Experimental and Molecular Medicine

A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment

Hyunwook Lee, Sarah A. Brendle, Stephanie M. Bywaters, Jian Guan, Robert E. Ashley, Joshua D. Yoder, Alexander M. Makhov, James F. Conway, Neil D. Christensen, Susan Hafenstein, 2015, Journal of Virology on p. 1428-1438

Secondary infections, expanded tissue tropism, and evidence for malignant potential in immunocompromised mice infected with Mus musculus papillomavirus 1 DNA and virus

Nancy M. Cladel, Lynn R. Budgeon, Timothy K. Cooper, Karla K. Balogh, Jiafen Hu, Neil D. Christensen, 2013, Journal of Virology on p. 9391-9395

Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization

Jian Guan, Stephanie M. Bywaters, Sarah A. Brendle, Hyunwook Lee, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Neil Christensen, Susan Hafenstein, 2015, Virology on p. 253-263

Low doses of flagellin-L2 multimer vaccines protect against challenge with diverse papillomavirus genotypes

Kirill Kalnin, Timothy Tibbitts, Yanhua Yan, Svetlana Stegalkina, Lihua Shen, Victor Costa, Robert Sabharwal, Stephen F. Anderson, Patricia M. Day, Neil Christensen, John T. Schiller, Subhashini Jagu, Richard B.S. Roden, Jeffrey Almond, Harold Kleanthous, 2014, Vaccine on p. 3540-3547

A novel pre-clinical murine model to study the life cycle and progression of cervical and anal papillomavirus infections

Nancy M. Cladel, Lynn R. Budgeon, Karla K. Balogh, Timothy K. Cooper, Jiafen Hu, Neil D. Christensen, 2015, PLoS One

Chimeric L2-based virus-like particle (VLP) vaccines targeting cutaneous human papillomaviruses (HPV)

Bettina Huber, Christina Schellenbacher, Saeed Shafti-Keramat, Christoph Jindra, Neil Christensen, Reinhard Kirnbauer, 2017, PLoS One

Recent advances in preclinical model systems for papillomaviruses

Neil D. Christensen, Lynn R. Budgeon, Nancy M. Cladel, Jiafen Hu, 2017, Virus Research on p. 108-118

The mouse papillomavirus infection model

Jiafen Hu, Nancy M. Cladel, Lynn R. Budgeon, Karla K. Balogh, Neil D. Christensen, 2017, Viruses