Neil Christensen

Professor of Pathology and Microbiology and Immunology

H059 Pathology
Hershey, PA
ndc1@psu.edu
717-531-6185

Bio & Links
Publications

Most Recent Publications

The full transcription map of cottontail rabbit papillomavirus in tumor tissues

Pengfei Jiang, Vladimir Majerciak, Jiafen Hu, Karla Balogh, Thomas J. Meyer, Maggie Cam, Debra Shearer, Matthew Lanza, Neil Christensen, Zhi Ming Zheng, 2024, PLoS Pathogens

ESCRT Protein VPS4A Is Required for the Formation of Replication Centers and Replication of Human Coronavirus 229E (HCoV-229E)

Rinki Kumar, Rebecca Kaddis Maldonado, Neil Christensen, Maria C. Bewley, John Flanagan, Nicholas Buchkovich, Leslie Parent, 2024, COVID on p. 1338-1354

Monitoring mouse papillomavirus-associated cancer development using longitudinal Pap smear screening

Hannah M. Atkins, Aysegul Aksakal Uslu, Jingwei J. Li, Debra A. Shearer, Sarah A. Brendle, Chen Han, Michael Kozak, Paul Lopez, Deesha Nayar, Karla K. Balogh, Catherine Abendroth, Jean Copper, Keith C. Cheng, Neil D. Christensen, Yusheng Zhu, Stefanie Avril, Adam D. Burgener, Thomas T. Murooka, Jiafen Hu, 2024, mBio on p. e0142024

A Combined LC-MS and Immunoassay Approach to Characterize Preservative-Induced Destabilization of Human Papillomavirus Virus-like Particles Adsorbed to an Aluminum-Salt Adjuvant

Ria T. Caringal, John M. Hickey, Nitya Sharma, Kaushal Jerajani, Oluwadara Bewaji, Sarah Brendle, Neil Christensen, Saurabh Batwal, Mustafa Mahedvi, Harish Rao, Vikas Dogar, Rahul Chandrasekharan, Umesh Shaligram, Sangeeta B. Joshi, David B. Volkin, 2024, Vaccines

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice

Mana Momenilandi, Romain Lévy, Steicy Sobrino, Jingwei Li, Chantal Lagresle-Peyrou, Hossein Esmaeilzadeh, Antoine Fayand, Corentin Le Floc'h, Antoine Guérin, Erika Della Mina, Debra Shearer, Ottavia M. Delmonte, Ahmad Yatim, Kevin Mulder, Mathieu Mancini, Darawan Rinchai, Adeline Denis, Anna Lena Neehus, Karla Balogh, Sarah Brendle, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Yoann Seeleuthner, Caroline Deswarte, Boris Bessot, Cassandre Cremades, Marie Materna, Axel Cederholm, Masato Ogishi, Quentin Philippot, Omer Beganovic, Mania Ackermann, Margareta Wuyts, Taushif Khan, Sébastien Fouéré, Florian Herms, Johan Chanal, Boaz Palterer, Julie Bruneau, Thierry J. Molina, Stéphanie Leclerc-Mercier, Jean Luc Prétet, Leila Youssefian, Hassan Vahidnezhad, Nima Parvaneh, Kristl G. Claeys, Rik Schrijvers, Marine Luka, Philippe Pérot, Jacques Fourgeaud, Céline Nourrisson, Philippe Poirier, Emmanuelle Jouanguy, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Luigi D. Notarangelo, Neil Christensen, Nils Landegren, Laurent Abel, Nico Marr, Emmanuelle Six, David Langlais, Tim Waterboer, Florent Ginhoux, Cindy S. Ma, Stuart G. Tangye, Isabelle Meyts, Nico Lachmann, Jiafen Hu, Mohammad Shahrooei, Xavier Bossuyt, Jean Laurent Casanova, Vivien Béziat, 2024, Cell on p. 2817-2837.e31

Multi-Dose Formulation Development for a Quadrivalent Human Papillomavirus Virus-Like Particle-Based Vaccine: Part I - Screening of Preservative Combinations

Kaushal Jerajani, Ying Wan, Ozan S. Kumru, Swathi R. Pullagurla, Prashant Kumar, Nitya Sharma, Oluwadara Ogun, Shweta Mapari, Sarah Brendle, Neil D. Christensen, Saurabh Batwal, Mustafa Mahedvi, Harish Rao, Vikas Dogar, Rahul Chandrasekharan, Umesh Shaligram, Sangeeta B. Joshi, David B. Volkin, 2023, Journal of Pharmaceutical Sciences on p. 446-457

Multi-dose Formulation Development for a Quadrivalent Human Papillomavirus Virus-Like Particle-Based Vaccine: Part II- Real-time and Accelerated Stability Studies

Nitya Sharma, Kaushal Jerajani, Ying Wan, Ozan S. Kumru, Swathi R. Pullagurla, Oluwadara Ogun, Shweta Mapari, Sarah Brendle, Neil D. Christensen, Saurabh Batwal, Mustafa Mahedvi, Harish Rao, Vikas Dogar, Rahul Chandrasekharan, Umesh Shaligram, David B. Volkin, Sangeeta B. Joshi, 2023, Journal of Pharmaceutical Sciences on p. 458-470

Gender Difference in DNA Damage Induced by the Environmental Carcinogen Dibenzo[def,p]chrysene Individually and in Combination with Mouse Papillomavirus Infection in the Mouse Oral Cavity

Kun-Ming Chen, Yuan-Wan Sun, Jiafen Hu, Karla Balogh, Krishne Gowda, Cesar Aliaga, Dongxiao Sun, Neil Christensen, Shantu Amin, Karam El-Bayoumy, K El Bayoumy, 2023, ACS Omega

Immune Responses in Oral Papillomavirus Clearance in the MmuPV1 Mouse Model

Sarah A. Brendle, Jingwei J. Li, Vonn Walter, Todd Schell, Michael Kozak, Karla K. Balogh, Song Lu, Neil D. Christensen, Yusheng Zhu, Karam El-Bayoumy, Jiafen Hu, 2023, Pathogens on p. 1452

Analytical and Preformulation Characterization Studies of Human Papillomavirus Virus-Like Particles to Enable Quadrivalent Multi-Dose Vaccine Formulation Development

Kaushal Jerajani, Ying Wan, John M. Hickey, Ozan S. Kumru, Nitya Sharma, Swathi R. Pullagurla, Oluwadara Ogun, Shweta Mapari, Neal Whitaker, Sarah Brendle, Neil D. Christensen, Saurabh Batwal, Mustafa Mahedvi, Harish Rao, Vikas Dogar, Rahul Chandrasekharan, Umesh Shaligram, Sangeeta B. Joshi, David B. Volkin, 2022, Journal of Pharmaceutical Sciences on p. 2983-2997

Most-Cited Papers

The wide utility of rabbits as models of human diseases

Pedro J. Esteves, Joana Abrantes, Hanna Mari Baldauf, Lbachir BenMohamed, Yuxing Chen, Neil Christensen, Javier González-Gallego, Lorenzo Giacani, Jiafen Hu, Gilla Kaplan, Oliver T. Keppler, Katherine L. Knight, Xiang Peng Kong, Dennis K. Lanning, Jacques Le Pendu, Ana Lemos De Matos, Jia Liu, Shuying Liu, Ana M. Lopes, Shan Lu, Sheila Lukehart, Yukari C. Manabe, Fabiana Neves, Grant McFadden, Ruimin Pan, Xuwen Peng, Patricia de Sousa-Pereira, Ana Pinheiro, Masmudur Rahman, Natalie Ruvoën-Clouet, Selvakumar Subbian, Maria Jesús Tuñón, Wessel van der Loo, Michael Vaine, Laura E. Via, Shixia Wang, Rose Mage, 2018, Experimental and Molecular Medicine

Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

Vivien Béziat, Franck Rapaport, Jiafen Hu, Matthias Titeux, Mathilde Bonnet des Claustres, Mathieu Bourgey, Heather Griffin, Élise Bandet, Cindy S. Ma, Roya Sherkat, Hassan Rokni-Zadeh, David M. Louis, Majid Changi-Ashtiani, Ottavia M. Delmonte, Toshiaki Fukushima, Tanwir Habib, Andrea Guennoun, Taushif Khan, Noemi Bender, Mahbuba Rahman, Frédégonde About, Rui Yang, Geetha Rao, Claire Rouzaud, Jingwei Li, Debra Shearer, Karla Balogh, Fatima Al Ali, Manar Ata, Soroosh Dabiri, Mana Momenilandi, Justine Nammour, Marie Alexandra Alyanakian, Marianne Leruez-Ville, David Guenat, Marie Materna, Léa Marcot, Natasha Vladikine, Christine Soret, Hassan Vahidnezhad, Leila Youssefian, Amir Hossein Saeidian, Jouni Uitto, Émilie Catherinot, Shadi Sadat Navabi, Mohammed Zarhrate, David T. Woodley, Mohamed Jeljeli, Thomas Abraham, Serkan Belkaya, Lazaro Lorenzo, Jérémie Rosain, Mousa Bayat, Fanny Lanternier, Olivier Lortholary, Faramarz Zakavi, Philippe Gros, Gérard Orth, Laurent Abel, Jean Luc Prétet, Sylvie Fraitag, Emmanuelle Jouanguy, Mark M. Davis, Stuart G. Tangye, Luigi D. Notarangelo, Nico Marr, Tim Waterboer, David Langlais, John Doorbar, Alain Hovnanian, Neil Christensen, Xavier Bossuyt, Mohammad Shahrooei, Jean Laurent Casanova, 2021, Cell on p. 3812-3828.e30

A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment

Hyunwook Lee, Sarah A. Brendle, Stephanie M. Bywaters, Jian Guan, Robert E. Ashley, Joshua D. Yoder, Alexander M. Makhov, James F. Conway, Neil D. Christensen, Susan Hafenstein, 2015, Journal of Virology on p. 1428-1438

Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization

Jian Guan, Stephanie M. Bywaters, Sarah A. Brendle, Hyunwook Lee, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Neil Christensen, Susan Hafenstein, 2015, Virology on p. 253-263

Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models

Nancy M. Cladel, Pengfei Jiang, Jingwei J. Li, Xuwen Peng, Timothy K. Cooper, Vladimir Majerciak, Karla K. Balogh, Thomas J. Meyer, Sarah A. Brendle, Lynn R. Budgeon, Debra A. Shearer, Regina Munden, Maggie Cam, Raghavan Vallur, Neil D. Christensen, Zhi Ming Zheng, Jiafen Hu, 2019, Emerging Microbes and Infections on p. 1108-1121