Molly Hall
Dr. Frances Keesler Graham Early Career Professor; Assistant Professor of Veterinary and Biomedical Sciences
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512A Wartik Lab
University Park, PA - mah546@psu.edu
- 814-865-0794
Research Summary
Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.
Huck Graduate Students
Huck Affiliations
- Bioinformatics and Genomics
- Molecular, Cellular, and Integrative Biosciences
- Integrative and Biomedical Physiology
- Center for Molecular Toxicology and Carcinogenesis
Links
Publication Tags
Genes Health Genomics Single Nucleotide Polymorphism Phenotype Fatty Acids Electronic Health Records Genome Wide Association Study Quality Control Cataract Gene Metabolomics Electronics Genome Precision Medicine Datasets Polymorphism Smoking (1,2 Diamino 4 Nitrobenzene)Dichloroplatinum(Ii) Environmental Exposure Glaucoma Nuclear Magnetic Resonance Pleiotropy Software MedicineMost Recent Papers
Hypothalamic-pituitary-adrenal axis dysregulation and risk for obesity in sexually abused females
J Li, Molly Hall, F Putnam, J Noll, 2022, Psychoneuroendocrinology
Dynamic assessment of the COVID-19 vaccine acceptance leveraging social media data
Lingyao Li, Jiayan Zhou, Zihui Ma, Michelle T. Bensi, Molly A. Hall, Gregory B. Baecher, 2022, Journal of Biomedical Informatics
Sex differences in the metabolome of Alzheimer's disease progression
Tomas Gonzlaez-Zarzar, Brian Lee, Rory Coughlin, Dokyoon Kim, Li Shen, Molly Hall, 2022, Frontiers in Radiology
Novel EDGE encoding method enhances ability to identify genetic interactions
Molly A. Hall, John Wallace, Anastasia M. Lucas, Yuki Bradford, Shefali S. Verma, Bertram Müller-Myhsok, Kristin Passero, Jiayan Zhou, John McGuigan, Beibei Jiang, Sarah A. Pendergrass, Yanfei Zhang, Peggy Peissig, Murray Brilliant, Patrick Sleiman, Hakon Hakonarson, John B. Harley, Krzysztof Kiryluk, Kristel van Steen, Jason H. Moore, Marylyn D. Ritchie, 2021, PLoS Genetics
Can social media be utilized to enhance early warning: Retrospective analysis of the U.S. COVID-19 pandemic outbreak
L Lingyao, L Gao, J Zhou, Z Ma, Molly Hall, 2021, medRxiv
Semi-automated NMR Pipeline for Environmental Exposures: New Insights on the Metabolomics of Smokers versus Non-smokers
Morris A. Aguilar, John McGuigan, Molly A. Hall, 2021, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 316-327
What About the Environment? Leveraging Multi-Omic Datasets to Characterize the Environment’s Role in Human Health.
K Passero, S Setia-Verma, K McAllister, A Manrai, C Patel, Molly Hall, 2021, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 309-315
Investigation of gene-gene interactions in cardiac diseases and serum fatty acid levels in LURIC cohort
Jiayan Zhou, Kristin Passero, Nicole E. Palmiero, Bertram Müller-Myhsok, Marcus E. Kleber, Winfried Maerz, Molly A. Hall, 2020, PLoS One
Phenome-wide association studies on cardiovascular health and fatty acids considering phenotype quality control practices for epidemiological data
Kristin Passero, Xi He, Jiayan Zhou, Bertram Mueller-Myhsok, Marcus E. Kleber, Winfried Maerz, Molly A. Hall, 2020, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 659-670
CLARITE Facilitates the Quality Control and Analysis Process for EWAS of Metabolic-Related Traits
Anastasia M. Lucas, Nicole E. Palmiero, John McGuigan, Kristin Passero, Jiayan Zhou, Deven Orie, Marylyn D. Ritchie, Molly A. Hall, 2019, Frontiers in Genetics
Most-Cited Papers
Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health
Arjun K. Manrai, Yuxia Cui, Pierre R. Bushel, Molly Hall, Spyros Karakitsios, Carolyn J. Mattingly, Marylyn Ritchie, Charles Schmitt, Denis A. Sarigiannis, Duncan C. Thomas, David Wishart, David M. Balshaw, Chirag J. Patel, 2017, Annual Review of Public Health on p. 279-294
Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study
Molly A. Hall, Anurag Verma, Kristin D. Brown-Gentry, Robert Goodloe, Jonathan Boston, Sarah Wilson, Bob McClellan, Cara Sutcliffe, Holly H. Dilks, Nila B. Gillani, Hailing Jin, Ping Mayo, Melissa Allen, Nathalie Schnetz-Boutaud, Dana C. Crawford, Marylyn D. Ritchie, Sarah A. Pendergrass, 2014, PLoS Genetics
Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank
Molly A. Hall, Scott M. Dudek, Robert Goodloe, Dana C. Crawford, Sarah A. Pendergrass, Peggy Peissig, Murray Brilliant, Catherine A. McCarty, Marylyn D. Ritchie, 2014, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 200-211
Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium
Shefali Setia Verma, Jessica N. Cooke Bailey, Anastasia Lucas, Yuki Bradford, James G. Linneman, Michael A. Hauser, Louis R. Pasquale, Peggy L. Peissig, Murray H. Brilliant, Catherine A. McCarty, Jonathan L. Haines, Janey L. Wiggs, Tamara R. Vrabec, Gerard Tromp, Marylyn D. Ritchie, Jonathan Bickel, Ariel Chandler, Ingrid Holm, Isaac Kohane, Shannon Manzi, Kyriacos Markianos, Nathan Palmer, Cassandra Perry, Guergana Savova, Wendy Wolf, Sek Wong Kong, Armand Antommaria, Beth Cobb, John Harley, John Hutton, Todd Lingren, John Lynch, Keith Marsolo, Melanie Myers, Bahram Namjou, Cindy Prows, Imre Solti, Sander Vinks, Michael Wagner, Debbie Abrams, Berta Almoguera, Rosetta Chiavacci, John Connolly, Marcella Devoto, Hakon Hakonarson, Brendan Keating, Cecilia Kim, Frank Mentch, Haijun Qui, Patrick Sleiman, 2016, PLoS Genetics
Electronic medical records and genomics (eMERGE) network exploration in cataract
Marylyn D. Ritchie, Shefali S. Verma, Molly A. Hall, Robert J. Goodloe, Richard L. Berg, Dave S. Carrell, Christopher S. Carlson, Lin Chen, David R. Crosslin, Joshua C. Denny, Gail Jarvik, Rongling Li, James G. Linneman, Jyoti Pathak, Peggy Peissig, Luke V. Rasmussen, Andrea H. Ramirez, Xiaoming Wang, Russell A. Wilke, Wendy A. Wolf, Eric S. Torstenson, Stephen D. Turner, Catherine A. McCarty, 2014, Molecular Vision on p. 1281-1295
The joint effect of air pollution exposure and copy number variation on risk for autism
Dokyoon Kim, Heather Volk, Santhosh Girirajan, Sarah Pendergrass, Molly A. Hall, Shefali S. Verma, Rebecca J. Schmidt, Robin L. Hansen, Debashis Ghosh, Yunin Ludena-Rodriguez, Kyoungmi Kim, Marylyn D. Ritchie, Irva Hertz-Picciotto, Scott B. Selleck, 2017, Autism Research on p. 1470-1480
PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies
Molly A. Hall, John Wallace, Anastasia Lucas, Dokyoon Kim, Anna O. Basile, Shefali S. Verma, Cathy A. McCarty, Murray H. Brilliant, Peggy L. Peissig, Terrie E. Kitchner, Anurag Verma, Sarah A. Pendergrass, Scott M. Dudek, Jason H. Moore, Marylyn D. Ritchie, 2017, Nature Communications
Embracing Complex Associations in Common Traits
Molly A. Hall, Jason H. Moore, Marylyn D. Ritchie, 2016, Trends in Genetics on p. 470-484
Next-generation analysis of cataracts
Sarah A. Pendergrass, Shefali S. Verma, Molly A. Hall, Emily R. Holzinger, Carrie B. Moore, John R. Wallace, Scott M. Dudek, Wayne Huggins, Terrie Kitchner, Carol Waudby, Richard Berg, Catherine A. McCarty, Marylyn D. Ritchie, 2013, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 147-158
Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network
Molly A. Hall, Shefali S. Verma, John Wallace, Anastasia Lucas, Richard L. Berg, John Connolly, Dana C. Crawford, David R. Crosslin, Mariza de Andrade, Kimberly F. Doheny, Jonathan L. Haines, John B. Harley, Gail P. Jarvik, Terrie Kitchner, Helena Kuivaniemi, Eric B. Larson, David S. Carrell, Gerard Tromp, Tamara R. Vrabec, Sarah A. Pendergrass, Catherine A. Mccarty, Marylyn D. Ritchie, 2015, Genetic Epidemiology on p. 376-384