Molly Hall

Dr. Frances Keesler Graham Early Career Professor; Assistant Professor of Veterinary and Biomedical Sciences

Molly Hall

Research Summary

Building tools to elucidate the complex genetic and environmental underpinnings of human disease. Integrating genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status.

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Publication Tags

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Genes Genomics Single Nucleotide Polymorphism Phenotype Electronic Health Records Genome Wide Association Study Cataract Gene Electronics Genome Health Precision Medicine (1,2 Diamino 4 Nitrobenzene)Dichloroplatinum(Ii) Glaucoma Pleiotropy Vaccines Obesity Polymorphism Medicine Nutrition Surveys Type 2 Diabetes Mellitus Child Gene Environment Interaction Medical Problems Body Mass Index

Most Recent Publications

Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells

Fenghua Qian, Shaneice K. Nettleford, Jiayan Zhou, Brooke E. Arner, Molly A. Hall, Arati Sharma, Charyguly Annageldiyev, Randy M. Rossi, Diwakar B. Tukaramrao, Deborpita Sarkar, Shailaja Hegde, Ujjawal H. Gandhi, Emily R. Finch, Laura Goodfield, Michael D. Quickel, David F. Claxton, Robert F. Paulson, K. Sandeep Prabhu, 2023, Cell Reports

Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation

Sougat Misra, Tai-Jung Lee, Molly Hall, Aswathy Sebastian, John McGuigan, Chang Liao, Imhoi Koo, A Patterson, Randall Rossi, Molly Hall, Istvan Albert, others, K Prabhu, 2023, Redox Biology on p. 102571

Neuronally enriched microvesicle RNAs are differentially expressed in the serums of Parkinson’s patients

Morris A. Aguilar, Shauna Ebanks, Havell Markus, Mechelle Lewis, Vishal Midya, Kent Vrana, Xuemei Huang, Molly Hall, Yuka Imamura Kawasawa, 2023, Frontiers in Neuroscience

Hypothalamic-pituitary-adrenal axis dysregulation and risk for obesity in sexually abused females

J Li, Molly Hall, F Putnam, J Noll, 2022, Psychoneuroendocrinology

Obesity and accelerated epigenetic aging in a high-risk cohort of children

Laura Etzel, Waylon Hastings, Molly A. Hall, Christine M. Heim, Michael Meaney, Jennie G. Noll, K O'Donnell, E Rose, Kieran J. O’Donnell, H Schrier, I Pokhvisneva, C Shenk, Emma Rose, Hannah M.C. Schreier, Schreier HMC, I Shalev, Chad E. Shenk, Idan Shalev, 2022, Scientific Reports on p. 8328

Sex differences in the metabolome of Alzheimer's disease progression

Tomas Gonzlaez-Zarzar, Brian Lee, Rory Coughlin, Dokyoon Kim, Li Shen, Molly Hall, 2022, Frontiers in Radiology

Dynamic assessment of the COVID-19 vaccine acceptance leveraging social media data

Lingyao Li, Jiayan Zhou, Zihui Ma, Michelle T. Bensi, Molly A. Hall, Gregory B. Baecher, 2022, Journal of Biomedical Informatics

Hypothalamic-pituitary-adrenal axis attenuation and obesity risk in sexually abused females

Jacinda Li, Molly A. Hall, Idan Shalev, Hannah M.C. Schreier, Tom´as Gonz´alez Zarzar, Isabel Marcovici, Frank Putnam, Jennie G. Noll, 2021, Psychoneuroendocrinology

Novel EDGE encoding method enhances ability to identify genetic interactions

Molly A. Hall, John Wallace, Anastasia M. Lucas, Yuki Bradford, Shefali S. Verma, Bertram Müller-Myhsok, Kristin Passero, Jiayan Zhou, John McGuigan, Beibei Jiang, Sarah A. Pendergrass, Yanfei Zhang, Peggy Peissig, Murray Brilliant, Patrick Sleiman, Hakon Hakonarson, John B. Harley, Krzysztof Kiryluk, Kristel van Steen, Jason H. Moore, Marylyn D. Ritchie, 2021, PLoS Genetics

Can social media be utilized to enhance early warning: Retrospective analysis of the U.S. COVID-19 pandemic outbreak

L Lingyao, L Gao, J Zhou, Z Ma, Molly Hall, 2021, medRxiv

Most-Cited Papers

Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health

Arjun K. Manrai, Yuxia Cui, Pierre R. Bushel, Molly Hall, Spyros Karakitsios, Carolyn J. Mattingly, Marylyn Ritchie, Charles Schmitt, Denis A. Sarigiannis, Duncan C. Thomas, David Wishart, David M. Balshaw, Chirag J. Patel, 2017, Annual Review of Public Health on p. 279-294

Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study

Molly A. Hall, Anurag Verma, Kristin D. Brown-Gentry, Robert Goodloe, Jonathan Boston, Sarah Wilson, Bob McClellan, Cara Sutcliffe, Holly H. Dilks, Nila B. Gillani, Hailing Jin, Ping Mayo, Melissa Allen, Nathalie Schnetz-Boutaud, Dana C. Crawford, Marylyn D. Ritchie, Sarah A. Pendergrass, 2014, PLoS Genetics

Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank

Molly A. Hall, Scott M. Dudek, Robert Goodloe, Dana C. Crawford, Sarah A. Pendergrass, Peggy Peissig, Murray Brilliant, Catherine A. McCarty, Marylyn D. Ritchie, 2014, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 200-211

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

Shefali Setia Verma, Jessica N. Cooke Bailey, Anastasia Lucas, Yuki Bradford, James G. Linneman, Michael A. Hauser, Louis R. Pasquale, Peggy L. Peissig, Murray H. Brilliant, Catherine A. McCarty, Jonathan L. Haines, Janey L. Wiggs, Tamara R. Vrabec, Gerard Tromp, Marylyn D. Ritchie, Jonathan Bickel, Ariel Chandler, Ingrid Holm, Isaac Kohane, Shannon Manzi, Kyriacos Markianos, Nathan Palmer, Cassandra Perry, Guergana Savova, Wendy Wolf, Sek Wong Kong, Armand Antommaria, Beth Cobb, John Harley, John Hutton, Todd Lingren, John Lynch, Keith Marsolo, Melanie Myers, Bahram Namjou, Cindy Prows, Imre Solti, Sander Vinks, Michael Wagner, Debbie Abrams, Berta Almoguera, Rosetta Chiavacci, John Connolly, Marcella Devoto, Hakon Hakonarson, Brendan Keating, Cecilia Kim, Frank Mentch, Haijun Qui, Patrick Sleiman, 2016, PLoS Genetics

The joint effect of air pollution exposure and copy number variation on risk for autism

Dokyoon Kim, Heather Volk, Santhosh Girirajan, Sarah Pendergrass, Molly A. Hall, Shefali S. Verma, Rebecca J. Schmidt, Robin L. Hansen, Debashis Ghosh, Yunin Ludena-Rodriguez, Kyoungmi Kim, Marylyn D. Ritchie, Irva Hertz-Picciotto, Scott B. Selleck, 2017, Autism Research on p. 1470-1480

Electronic medical records and genomics (eMERGE) network exploration in cataract: Several new potential susceptibility loci

Marylyn D. Ritchie, Shefali S. Verma, Molly A. Hall, Robert J. Goodloe, Richard L. Berg, Dave S. Carrell, Christopher S. Carlson, Lin Chen, David R. Crosslin, Joshua C. Denny, Gail Jarvik, Rongling Li, James G. Linneman, Jyoti Pathak, Peggy Peissig, Luke V. Rasmussen, Andrea H. Ramirez, Xiaoming Wang, Russell A. Wilke, Wendy A. Wolf, Eric S. Torstenson, Stephen D. Turner, Catherine A. McCarty, 2014, Molecular Vision on p. 1281-1295

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

Molly A. Hall, John Wallace, Anastasia Lucas, Dokyoon Kim, Anna O. Basile, Shefali S. Verma, Cathy A. McCarty, Murray H. Brilliant, Peggy L. Peissig, Terrie E. Kitchner, Anurag Verma, Sarah A. Pendergrass, Scott M. Dudek, Jason H. Moore, Marylyn D. Ritchie, 2017, Nature Communications

Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine

Molly A. Hall, Jason H. Moore, Marylyn D. Ritchie, 2016, Trends in Genetics on p. 470-484

Next-generation analysis of cataracts: Determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the PhenX Toolkit

Sarah A. Pendergrass, Shefali S. Verma, Molly A. Hall, Emily R. Holzinger, Carrie B. Moore, John R. Wallace, Scott M. Dudek, Wayne Huggins, Terrie Kitchner, Carol Waudby, Richard Berg, Catherine A. McCarty, Marylyn D. Ritchie, 2013, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing on p. 147-158

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

Molly A. Hall, Shefali S. Verma, John Wallace, Anastasia Lucas, Richard L. Berg, John Connolly, Dana C. Crawford, David R. Crosslin, Mariza de Andrade, Kimberly F. Doheny, Jonathan L. Haines, John B. Harley, Gail P. Jarvik, Terrie Kitchner, Helena Kuivaniemi, Eric B. Larson, David S. Carrell, Gerard Tromp, Tamara R. Vrabec, Sarah A. Pendergrass, Catherine A. Mccarty, Marylyn D. Ritchie, 2015, Genetic Epidemiology on p. 376-384