Mechelle Lewis
Associate Professor Neurology and Pharmacology
Huck Affiliations
Publication Tags
Parkinson Disease Manganese Substantia Nigra Iron Brain Synucleins Prions Inflammasomes Semantics Neurotoxicity Paraquat Levodopa Anisotropy Putamen Cerebrospinal Fluid Pars Compacta Corpus Striatum Pharmaceutical Preparations Machine Learning Pathology Red Nucleus Mental Status And Dementia Tests Exosomes Sensors FarmersMost Recent Papers
Folded concave penalized learning of high-dimensional MRI data in Parkinson's disease
Changcheng Li, Xue Wang, Guangwei Du, Hairong Chen, Gregory Brown, Mechelle M. Lewis, Tao Yao, Runze Li, Xuemei Huang, 2021, Journal of Neuroscience Methods
HFE H63D Limits Nigral Vulnerability to Paraquat in Agricultural Workers
Ernest W. Wang, Max L. Trojano, Mechelle M. Lewis, Guangwei Du, Hairong Chen, Gregory L. Brown, Leslie C. Jellen, Insung Song, Elizabeth Neely, Lan Kong, James R. Connor, Xuemei Huang, 2021, Toxicological Sciences on p. 47-57
Nigral MRI features of asymptomatic welders
Eun Young Lee, Michael R. Flynn, Guangwei Du, Mechelle M. Lewis, Michael Goldenberg, Lan Kong, Richard B. Mailman, Young Seoub Hong, Xuemei Huang, 2021, Parkinsonism and Related Disorders on p. 37-43
Choroidal Thickness Correlates with Clinical and Imaging Metrics of Parkinson's Disease
Gregory L. Brown, Mona L. Camacci, Sean D. Kim, Stephanie Grillo, James V. Nguyen, Douglas A. Brown, Sarah P. Ullah, Mechelle Lewis, Guangwei Du, Lan Kong, Jeffrey M. Sundstrom, Xuemei Huang, Esther M. Bowie, 2021, Journal of Parkinson's Disease on p. 1857-1868
Decoupling of Global Brain Activity and Cerebrospinal Fluid Flow in Parkinson's Disease Cognitive Decline
Feng Han, Gregory L. Brown, Yalin Zhu, Aaron E. Belkin-Rosen, Mechelle M. Lewis, Guangwei Du, Yameng Gu, Paul J. Eslinger, Richard B. Mailman, Xuemei Huang, Xiao Liu, 2021, Movement Disorders
Synergic control of action in levodopa-naïve Parkinson’s disease patients: II. Multi-muscle synergies stabilizing vertical posture
Sandra M.S.F. Freitas, Freitas SMSF, P de Freitas, A Falaki, T Corson, Mechelle M. Lewis, Xuemei Huang, Mark L. Latash, 2020, Experimental Brain Research on p. 2931-2945
Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
Patrick L. Heilman, Ernest W. Wang, Mechelle M. Lewis, Stanislaw Krzyzanowski, Colt D. Capan, Amanda R. Burmeister, Guangwei Du, Martha L. Escobar Galvis, Patrik Brundin, Xuemei Huang, Lena Brundin, 2020, Movement Disorders on p. 2028-2037
The D<sub>1</sub>/D<sub>5</sub>Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson's Disease
Xuemei Huang, Mechelle M. Lewis, Lauren Van Scoy, Sol De Jesus, Paul J. Eslinger, Amy C. Arnold, Amanda J. Miller, Julio Fernandez-Mendoza, Bethany Snyder, William Harrington, Lan Kong, Xi Wang, Dongxiao Sun, Marielle Delnomdedieu, Sridhar Duvvuri, Susan E. Mahoney, David L. Gray, Richard Mailman, 2020, Journal of Parkinson's Disease on p. 1515-1527
Lexical-semantic search related to side of onset and putamen volume in Parkinson's disease
Daymond Wagner, Paul J. Eslinger, Nicholas W. Sterling, Guangwei Du, Eun Young Lee, Martin Styner, Mechelle M. Lewis, Xuemei Huang, 2020, Brain and Language
Factors Influencing Pediatric Recovery from Traumatic Brain Injury.
A. Feldman, S. Thomas, J. Hess, Mechelle Lewis, 2020, Penn State J. Med.
Most-Cited Papers
Quantitative susceptibility mapping of the midbrain in Parkinson's disease
Guangwei Du, Tian Liu, Mechelle M. Lewis, Lan Kong, Yi Wang, James Connor, Richard B. Mailman, Xuemei Huang, 2016, Movement Disorders on p. 317-324
Changes in multifinger interaction and coordination in Parkinson's disease
Jaebum Park, Yen Hsun Wu, Mechelle M. Lewis, Xuemei Huang, Mark L. Latash, 2012, Journal of Neurophysiology on p. 915-924
Imaging nigral pathology and clinical progression in Parkinson's disease
Guangwei Du, Mechelle M. Lewis, Suman Sen, Jianli Wang, Michele L. Shaffer, Martin Styner, Qing X. Yang, Xuemei Huang, 2012, Movement Disorders on p. 1636-1643
Both coordination and symmetry of arm swing are reduced in Parkinson's disease
Xuemei Huang, Joseph M. Mahoney, Mechelle M. Lewis, Guangwei Du, Stephen J. Piazza, Joseph P. Cusumano, 2012, Gait and Posture on p. 373-377
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
Dilshan S. Harischandra, Dharmin Rokad, Matthew L. Neal, Shivani Ghaisas, Sireesha Manne, Souvarish Sarkar, Nikhil Panicker, Gary Zenitsky, Huajun Jin, Mechelle Lewis, Xuemei Huang, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy, 2019, Science's STKE : signal transduction knowledge environment
Striatal shape in Parkinson's disease
Nicholas W. Sterling, Guangwei Du, Mechelle M. Lewis, Christopher Dimaio, Lan Kong, Paul J. Eslinger, Martin Styner, Xuemei Huang, 2013, Neurobiology of Aging on p. 2510-2516
Effects of olivo-ponto-cerebellar atrophy (OPCA) on finger interaction and coordination
Jaebum Park, Mechelle Lewis, Xuemei Huang, Mark Latash, 2013, Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control on p. 991-998
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
Souvarish Sarkar, Dharmin Rokad, Emir Malovic, Jie Luo, Dilshan S. Harischandra, Huajun Jin, Vellareddy Anantharam, Xuemei Huang, Mechelle Lewis, Arthi Kanthasamy, Anumantha G. Kanthasamy, 2019, Science's STKE : signal transduction knowledge environment
Higher iron in the red nucleus marks Parkinson's dyskinesia
Mechelle Lewis, Guangwei Du, Michal Kidacki, Nisargkumar Patel, Michele L. Shaffer, Richard Mailman, Xuemei Huang, 2013, Neurobiology of Aging on p. 1497-1503
Machine learning classification of medication adherence in patients with movement disorders using non-wearable sensors
Conrad S. Tucker, Ishan Behoora, Harriet Black Nembhard, Mechelle Lewis, Nicholas W. Sterling, Xuemei Huang, 2015, Computers in Biology and Medicine on p. 120-134