Mechelle Lewis
Associate Professor Neurology and Pharmacology
Huck Affiliations
Publication Tags
Parkinson Disease Substantia Nigra Synucleins Manganese Pathology Anisotropy Brain Corpus Striatum Prions Semantics Putamen Parkinsonian Disorders Cerebrospinal Fluid Magnetic Resonance Imaging Biomarkers Diffusion Tensor Imaging Tremor Mental Status And Dementia Tests Arm Tryptophan Feasibility Studies Common Data Elements Olivopontocerebellar Atrophies Parkinson's Disease HippocampusMost Recent Papers
Folded concave penalized learning of high-dimensional MRI data in Parkinson's disease
Changcheng Li, Xue Wang, Guangwei Du, Hairong Chen, Gregory Brown, Mechelle M. Lewis, Tao Yao, Runze Li, Xuemei Huang, 2021, Journal of Neuroscience Methods
Nigral MRI features of asymptomatic welders
Eun Young Lee, Michael R. Flynn, Guangwei Du, Mechelle M. Lewis, Michael Goldenberg, Lan Kong, Richard B. Mailman, Young Seoub Hong, Xuemei Huang, 2021, Parkinsonism and Related Disorders on p. 37-43
HFE H63D limits nigral vulnerability to paraquat in agricultural workers
E. Wang, M. Trojano, Mechelle Lewis, 2021, Toxicol. Sci.
Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
Patrick L. Heilman, Ernest W. Wang, Mechelle M. Lewis, Stanislaw Krzyzanowski, Colt D. Capan, Amanda R. Burmeister, Guangwei Du, Martha L. Escobar Galvis, Patrik Brundin, Xuemei Huang, Lena Brundin, 2020, Movement Disorders on p. 2028-2037
Lexical-semantic search related to side of onset and putamen volume in Parkinson's disease
Daymond Wagner, Paul J. Eslinger, Nicholas W. Sterling, Guangwei Du, Eun Young Lee, Martin Styner, Mechelle M. Lewis, Xuemei Huang, 2020, Brain and Language
The D<sub>1</sub>/D<sub>5</sub>Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson's Disease
Xuemei Huang, Mechelle M. Lewis, Lauren Van Scoy, Sol De Jesus, Paul J. Eslinger, Amy C. Arnold, Amanda J. Miller, Julio Fernandez-Mendoza, Bethany Snyder, William Harrington, Lan Kong, Xi Wang, Dongxiao Sun, Marielle Delnomdedieu, Sridhar Duvvuri, Susan E. Mahoney, David L. Gray, Richard Mailman, 2020, Journal of Parkinson's Disease on p. 1515-1527
Factors Influencing Pediatric Recovery from Traumatic Brain Injury.
A. Feldman, S. Thomas, J. Hess, Mechelle Lewis, 2020, Penn State J. Med.
Clinical Progression of Parkinson's Disease
Mechelle M. Lewis, Elias Harkins, Eun Young Lee, Christy Stetter, Bethany Snyder, Tyler Corson, Guangwei Du, Lan Kong, Xuemei Huang, 2020, Journal of Parkinson's Disease on p. 1075-1085
Ultrasensitive detection of aggregated α-Synuclein in glial cells, human cerebrospinal fluid, and brain tissue using the RT-QuIC assay: New hgh-throughput neuroimmune biomarker assay for Parkinsonian disorders
Sireesha Manne, Naveen Kondru, Monica Hepker, Huajun Jin, Vellareddy Anantharam, Mechelle Lewis, Xuemei Huang, Arthi Kanthasamy, Anumantha G. Kanthasamy, 2019, Journal of NeuroImmune Pharmacology on p. 423-435
Multimodal MRI evaluation of parkinsonian limbic pathologies
Ernest W. Wang, Guangwei Du, Mechelle M. Lewis, Eun Young Lee, Sol De Jesus, Sangam Kanekar, Lan Kong, Xuemei Huang, 2019, Neurobiology of Aging on p. 194-200
Most-Cited Papers
Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's disease
Guangwei Du, Mechelle M. Lewis, Martin Styner, Michele L. Shaffer, Suman Sen, Qing X. Yang, Xuemei Huang, 2011, Movement Disorders on p. 1627-1632
Differential involvement of striato- and cerebello-thalamo-cortical pathways in tremor- and akinetic/rigid-predominant Parkinson's disease
Mechelle Lewis, Guangwei Du, S. Sen, A. Kawaguchi, Y. Truong, S. Lee, Richard Mailman, Xuemei Huang, 2011, Neuroscience on p. 230-239
Changes in multifinger interaction and coordination in Parkinson's disease
Jaebum Park, Yen Hsun Wu, Mechelle M. Lewis, Xuemei Huang, Mark L. Latash, 2012, Journal of Neurophysiology on p. 915-924
Quantitative susceptibility mapping of the midbrain in Parkinson's disease
Guangwei Du, Tian Liu, Mechelle M. Lewis, Lan Kong, Yi Wang, James Connor, Richard B. Mailman, Xuemei Huang, 2016, Movement Disorders on p. 317-324
Imaging nigral pathology and clinical progression in Parkinson's disease
Guangwei Du, Mechelle M. Lewis, Suman Sen, Jianli Wang, Michele L. Shaffer, Martin Styner, Qing X. Yang, Xuemei Huang, 2012, Movement Disorders on p. 1636-1643
Both coordination and symmetry of arm swing are reduced in Parkinson's disease
Xuemei Huang, Joseph M. Mahoney, Mechelle M. Lewis, Du Guangwei Du, Stephen J. Piazza, Joseph P. Cusumano, 2012, Gait and Posture on p. 373-377
Striatal shape in Parkinson's disease
Nicholas W. Sterling, Guangwei Du, Mechelle Lewis, Christopher Dimaio, Lan Kong, Paul Eslinger, Martin Styner, Xuemei Huang, 2013, Neurobiology of Aging on p. 2510-2516
Effects of olivo-ponto-cerebellar atrophy (OPCA) on finger interaction and coordination
Jaebum Park, Mechelle Lewis, Xuemei Huang, Mark Latash, 2013, Clinical Neurophysiology on p. 991-998
Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients
Eun Young Lee, Suman Sen, Paul J. Eslinger, Daymond Wagner, Michele L. Shaffer, Lan Kong, Mechelle M. Lewis, Guangwei Du, Xuemei Huang, 2013, Parkinsonism and Related Disorders on p. 1088-1093
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
Dilshan S. Harischandra, Dharmin Rokad, Matthew L. Neal, Shivani Ghaisas, Sireesha Manne, Souvarish Sarkar, Nikhil Panicker, Gary Zenitsky, Huajun Jin, Mechelle Lewis, Xuemei Huang, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy, 2019, Science Signaling