Mary Jane De Souza
Distinguished Professor of Kinesiology
Research Summary
Women's health and Physical Activity, Endocrinology of the Female Athlete, Effects of Exercise on the Menstrual Cycle, Female Athlete Triad (Eating disorders, amenorrhea and osteoporosis), Eating Behaviors, Food Intake, and Exercise, Luteal Phase Defects and Amenorrhea, Bone Health and Osteoporosis in Female Athletes, and Energy Deficiency and Bone Health.
Huck Affiliations
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Female Athlete Triad Female Athlete Triad Syndrome Exercise Early Intervention Disordered Eating Therapeutics Consensus Return To Play Consensus Statement Return To Sport San Francisco Indianapolis Bone Mineral Density Bone Density International Conference Injury Conferences Congresses Glucuronides Menstruation Disorder Sports Health Care Metabolic Bone Diseases Physicians Energy IntakeMost Recent Publications
Effects of Prune (Dried Plum) Supplementation on Cardiometabolic Health in Postmenopausal Women: An Ancillary Analysis of a 12-Month Randomized Controlled Trial, The Prune Study.
J Damani, C Rogers, H Lee, N Strock, K Koltun, N Williams, C Weaver, M Ferruzzi, C Nakatsu, Mary Jane De Souza, 2024, The Journal of nutrition on p. 1604-1618
Prunes preserve cortical density and estimated strength of the tibia in a 12-month randomized controlled trial in postmenopausal women: The Prune Study
K Koltun, Strock NCA, Nicole C.A. Strock, C Weaver, H Lee, Nancy I. Williams, C Rogers, J Damani, M Ferruzzi, C Nakatsu, Mary Jane De Souza, 2024, Osteoporosis International on p. 863-875
Prune Consumption Attenuates Proinflammatory Cytokine Secretion and Alters Monocyte Activation in Postmenopausal Women: Secondary Outcome Analysis of a 12-Mo Randomized Controlled Trial: The Prune Study
Janhavi J. Damani, Ester S. Oh, Mary Jane De Souza, Nicole CA Strock, Nancy I. Williams, Cindy H. Nakatsu, Hang Lee, Connie Weaver, Connie J. Rogers, 2024, Journal of Nutrition on p. 1699-1710
Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density.
Simpson AMR, Mary Jane De Souza, J Damani, C Rogers, N Williams, C Weaver, M Ferruzzi, C Nakatsu, 2024, Frontiers in nutrition on p. 1389638
Are menstrual disturbances associated with an energy availability threshold? A critical review of the evidence
Ana Carla C. Salamunes, Nancy Williams, Mary Jane De Souza, 2024, Applied Physiology, Nutrition and Metabolism on p. 584-598
Seven-day dietary nitrate supplementation clinically significantly improves basal macrovascular function in postmenopausal women: a randomized, placebo-controlled, double-blind, crossover clinical trial
Jocelyn M. Delgado Spicuzza, Jigar Gosalia, Liezhou Zhong, Catherine Bondonno, Kristina Petersen, Mary Jane De Souza, Elmira Alipour, Daniel B. Kim-Shapiro, Yasina B. Somani, David N. Proctor, 2024, Frontiers in Nutrition
The Influence of Energy Balance and Availability on Resting Metabolic Rate: Implications for Assessment and Future Research Directions
Madelin R. Siedler, Mary Jane De Souza, Kembra Albracht-Schulte, Yasuki Sekiguchi, Grant M. Tinsley, 2023, Sports Medicine on p. 1507-1526
12-months of increased dietary intake does not exacerbate disordered eating-related attitudes, stress, or depressive symptoms in women with exercise-associated menstrual disturbances: The REFUEL randomized controlled trial
Strock NCA, Nicole C.A. Strock, Mary Jane De Souza, R Mallinson, M Olmsted, Heather C.M. Allaway, Allaway HCM, E O'Donnell, F Plessow, Nancy I. Williams, 2023, Psychoneuroendocrinology on p. 106079
Associations Between Inflammatory Mediators and Bone Outcomes in Postmenopausal Women: A Cross-Sectional Analysis of Baseline Data from the Prune Study
J Damani, Mary Jane De Souza, Nicole C.A. Strock, Strock NCA, K Koltun, Nancy I. Williams, C Weaver, Connie J. Rogers, 2023, Journal of Inflammation Research on p. 639-663
Sex differences and indications of metabolic compensation in within-day energy balance in elite Division 1 swimmers
E Lundstrom, Mary Jane De Souza, Mary Jane De Souza, H Canil, Nancy I. Williams, 2023, Applied Physiology, Nutrition and Metabolism on p. 74-87
Most-Cited Papers
2014 Female Athlete Triad Coalition Consensus Statement on Treatment and Return to Play of the Female Athlete Triad: 1st International conference held in San Francisco, California, May 2012 and 2nd International conference held in Indianapolis, Indiana, May 2013
Mary Jane De Souza, Aurelia Nattiv, Elizabeth Joy, Madhusmita Misra, Nancy I. Williams, Rebecca J. Mallinson, Jenna C. Gibbs, Marion Olmsted, Marci Goolsby, Gordon Matheson, 2014, British Journal of Sports Medicine on p. 289
Higher incidence of bone stress injuries with increasing female athlete triad-related risk factors: A prospective multisite study of exercising girls and women
Michelle T. Barrack, Jenna C. Gibbs, Mary Jane De Souza, Nancy I. Williams, Jeanne F. Nichols, Mitchell J. Rauh, Aurelia Nattiv, 2014, The Journal of sports medicine on p. 949-958
Ovarian suppression impairs sport performance in junior elite female swimmers
Jaci L. Vanheest, Carol D. Rodgers, Carrie E. Mahoney, Mary Jane De Souza, 2014, Medicine and Science in Sports and Exercise on p. 156-166
2014 female athlete triad coalition consensus statement on treatment and return to play of the female athlete triad: 1st international conference held in San Francisco, CA, May 2012, and 2nd international conference held in Indianapolis, IN, May 2013
Mary Jane De Souza, Aurelia Nattiv, Elizabeth Joy, Madhusmita Misra, Nancy I. Williams, Rebecca J. Mallinson, Jenna C. Gibbs, Marion Olmsted, Marci Goolsby, Gordon Matheson, 2014, Clinical Journal of Sport Medicine on p. 96-119
Low energy availability in exercising men is associated with reduced leptin and insulin but not with changes in other metabolic hormones
Karsten Koehler, Neele R. Hoerner, Jenna C. Gibbs, Christoph Zinner, Hans Braun, Mary Jane De Souza, Wilhelm Schaenzer, 2016, Journal of Sports Sciences on p. 1921-1929
2014 female athlete triad coalition consensus statement on treatment and return to play of the female athlete triad
Elizabeth Joy, Mary Jane De Souza, Aurelia Nattiv, Madhusmita Misra, Nancy I. Williams, Rebecca J. Mallinson, Jenna C. Gibbs, Marion Olmsted, Marci Goolsby, Gordon Matheson, Michelle Barrack, Louise Burke, Barbara Drinkwater, Connie Lebrun, Anne B. Loucks, Margo Mountjoy, Jeanne Nichols, Jorunn Sundgot Borgen, 2014, Current Sports Medicine Reports on p. 219-231
Magnitude of daily energy deficit predicts frequency but not severity of menstrual disturbances associated with exercise and caloric restriction
Nancy I. Williams, Heather J. Leidy, Brenna R. Hill, Jay L. Lieberman, Richard S. Legro, Mary Jane De Souza, 2015, American Journal of Physiology on p. E29-E39
Menstrual Disruption with Exercise Is Not Linked to an Energy Availability Threshold
Jay L. Lieberman, Mary Jane De Souza, David A. Wagstaff, Nancy I. Williams, 2018, Medicine and Science in Sports and Exercise on p. 551-561
Low bone density risk is higher in exercising women with multiple triad risk factors
Jenna C. Gibbs, Aurelia Nattiv, Michelle T. Barrack, Nancy I. Williams, Mitchell J. Rauh, Jeanne F. Nichols, Mary Jane De Souza, 2014, Medicine and Science in Sports and Exercise on p. 167-176
The Unexplored Crossroads of the Female Athlete Triad and Iron Deficiency: A Narrative Review
Dylan L. Petkus, Laura E. Murray-Kolb, Mary Jane De Souza, 2017, Sports Medicine on p. 1721-1737
News Articles Featuring Mary Jane De Souza
Jun 28, 2024
Eating Prunes Every Day May Help Keep Your Bones Strong As You Age, According To A New Study
Most people think of milk and cheese when it comes to foods that support good bone health. But new research suggests that prunes may do you a solid, too.
Full Article
Jun 26, 2024
New research shows prunes could prevent bone loss in older women
A new study has shown positive results in using prunes to improve bone health of postmenopausal women.
Full Article
Jun 26, 2024
A daily dose of prunes may preserve bone density and strength in older women, Penn State researchers say
Eating prunes daily may preserve bone density and strength in older women, according to a new study led by Penn State researchers.
Full Article
Jun 26, 2024
Prunes' New Health Benefit for Older Adults Revealed
Eating prunes has been long known to keep your toilet trips regular, but scientists have found another benefit of these dried fruit snacks. Prunes have been linked to improved bone structure and strength in postmenopausal women, according to a new paper in the journal Osteoporosis International.
Full Article
Jun 25, 2024
Got prunes? Prunes may preserve bone density and strength in older women
Dairy isn’t the only food that’s good for bone health. Prunes may also protect bone structure and strength in postmenopausal women, according to a new study led by Penn State researchers. The findings, published in Osteoporosis International, suggest that daily prune consumption slows the progression of age-related bone loss and reduces the risk of fracture.
Full Article
Jul 31, 2023
Penn State CTSI announces seven Bridges to Translation pilot funding recipients
Penn State Clinical and Translational Science Institute is helping to generate innovative health research ideas and promote collaboration through the awarding of pilot grants in its "Bridges to Translation" program.
Full Article
Dec 06, 2022
Prunes may help prevent bone loss and preserve bone strength
In the United States, about 10 million adults over the age of 50 have osteoporosis, with women four times more likely than men to experience the condition, according to prior research.
Full Article