Maciej F Boni

Associate Professor of Biology

Maciej F Boni

Research Summary

Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models

Huck Affiliations

Links

Publication Tags

Viruses Pandemics Sars Virus Poultry Chiroptera Population Artemisinine Plasmodium Falciparum Norovirus Genome Birds Malaria Epidemiology Epidemics Farms Parasites Disease Outbreaks Resistance Dogs Severe Acute Respiratory Syndrome Genetic Recombination Vietnam Genes Pandemic Gastroenteritis

Most Recent Papers

Using NS1 Flavivirus Protein Microarray to Infer Past Infecting Dengue Virus Serotype and Number of Past Dengue Virus Infections in Vietnamese Individuals

Tran Thi Nhu Thao, Erwin de Bruin, Huynh Thi Phuong, Nguyen Ha Thao Vy, Henk Jan van den Ham, Bridget A. Wills, Nguyen Thi Hanh Tien, Huynh Thi Le Duyen, Dinh The Trung, Stephen S. Whitehead, Maciej F. Boni, Marion Koopmans, Hannah E. Clapham, 2021, Journal of Infectious Diseases on p. 2053-2061

Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

Oscar A. MacLean, Spyros Lytras, Steven Weaver, Joshua B. Singer, Maciej F. Boni, Philippe Lemey, Sergei L. Kosakovsky Pond, David L. Robertson, 2021, PLoS Biology

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

Ambroise Ahouidi, Mozam Ali, Jacob Almagro-Garcia, Alfred Amambua-Ngwa, Chanaki Amaratunga, Roberto Amato, Lucas Amenga-Etego, Ben Andagalu, Tim J.C. Anderson, Voahangy Andrianaranjaka, Tobias Apinjoh, Cristina Ariani, Elizabeth A. Ashley, Sarah Auburn, Gordon Awandare, Hampate Ba, Vito Baraka, Alyssa E. Barry, Philip Bejon, Gwladys I. Bertin, Maciej F. Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C. Bull, George B.J. Busby, Thanat Chookajorn, Kesinee Chotivanich, Antoine Claessens, David Conway, Alister Craig, Umberto D'Alessandro, Souleymane Dama, Nicholas P.J. Day, Brigitte Denis, Mahamadou Diakite, Abdoulaye Djimdé, Christiane Dolecek, Arjen M. Dondorp, Chris Drakeley, Eleanor Drury, Patrick Duffy, Diego F. Echeverry, Thomas G. Egwang, Berhanu Erko, Rick M. Fairhurst, Abdul Faiz, Caterina A. Fanello, Mark M. Fukuda, Dionicia Gamboa, 2021, Wellcome Open Research

Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

Maciej F. Boni, Philippe Lemey, Xiaowei Jiang, Tommy Tsan Yuk Lam, Blair W. Perry, Todd A. Castoe, Andrew Rambaut, David L. Robertson, 2020, Nature Microbiology on p. 1408-1417

Viral CpG deficiency provides no evidence that dogs were intermediate hosts for SARS-CoV-2

David D. Pollock, Todd A. Castoe, Blair W. Perry, Spyros Lytras, Kristen J. Wade, David L. Robertson, Edward C. Holmes, Maciej F. Boni, Sergei L. Kosakovsky Pond, Rhys Parry, Elizabeth J. Carlton, James L.N. Wood, Pleuni S. Pennings, Richard A. Goldstein, 2020, Molecular Biology and Evolution on p. 2706-2710

Poultry farmer response to disease outbreaks in smallholder farming systems in Southern Vietnam

Alexis Delabouglise, Nguyen Thi Le Thanh, Huynh Thi Ai Xuyen, Benjamin Nguyen-Van-yen, Phung Ngoc Tuyet, Ha Minh Lam, Maciej F. Boni, 2020, eLife on p. 1-44

Serology for SARS-CoV-2

Juliet E. Bryant, Andrew S. Azman, Matthew J. Ferrari, Benjamin F. Arnold, Maciej F. Boni, Yap Boum, Kyla Hayford, Francisco J. Luquero, Michael J. Mina, Isabel Rodriguez-Barraquer, Joseph T. Wu, Djibril Wade, Guy Vernet, Daniel T. Leung, 2020, Science immunology

Serology for SARS-CoV-2: apprehensions, opportunities, and the path forward

Juliet Bryant, 2020, on p. eabc6347

Game theory of vaccination and depopulation for managing livestock diseases and zoonoses on small-scale farms

Alexis Delabouglise, Maciej F. Boni, 2020, Epidemics

Game theory of vaccination and depopulation for managing avian influenza on poultry farms

Alexis Delabouglise, Maciej Boni, 2020, Epidemics

Most-Cited Papers

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Olivo Miotto, Jacob Almagro-Garcia, Magnus Manske, Bronwyn MacInnis, Susana Campino, Kirk A. Rockett, Chanaki Amaratunga, Pharath Lim, Seila Suon, Sokunthea Sreng, Jennifer M. Anderson, Socheat Duong, Chea Nguon, Char Meng Chuor, David Saunders, Youry Se, Chantap Lon, Mark M. Fukuda, Lucas Amenga-Etego, Abraham V.O. Hodgson, Victor Asoala, Mallika Imwong, Shannon Takala-Harrison, François Nosten, Xin Zhuan Su, Pascal Ringwald, Frédéric Ariey, Christiane Dolecek, Tran Tinh Hien, Maciej F. Boni, Cao Quang Thai, Alfred Amambua-Ngwa, David J. Conway, Abdoulaye A. Djimdé, Ogobara K. Doumbo, Issaka Zongo, Jean Bosco Ouedraogo, Daniel Alcock, Eleanor Drury, Sarah Auburn, Oliver Koch, Mandy Sanders, Christina Hubbart, Gareth Maslen, Valentin Ruano-Rubio, Dushyanth Jyothi, Alistair Miles, John O'Brien, Chris Gamble, Samuel O. Oyola, Julian C. Rayner, Chris I. Newbold, Matthew Berriman, Chris C.A. Spencer, Gilean McVean, Nicholas P. Day, Nicholas J. White, Delia Bethell, Arjen M. Dondorp, Christopher V. Plowe, Rick M. Fairhurst, Dominic P. Kwiatkowski, 2013, Nature Genetics on p. 648-655

Role for migratory wild birds in the global spread of avian influenza H5N8

Samantha J. Lycett, Rogier Bodewes, Anne Pohlmann, Jill Banks, Krisztián Bányai, Maciej F. Boni, Ruth Bouwstra, Andrew C. Breed, Ian H. Brown, Hualan Chen, Ádám Dán, Thomas J. DeLiberto, Nguyen Diep, Marius Gilbert, Sarah Hill, Hon S. Ip, Chang Wen Ke, Hiroshi Kida, Mary Lea Killian, Marion P. Koopmans, Jung Hoon Kwon, Dong Hun Lee, Youn Jeong Lee, Lu Lu, Isabella Monne, John Pasick, Oliver G. Pybus, Andrew Rambaut, Timothy P. Robinson, Yoshihiro Sakoda, Siamak Zohari, Chang Seon Song, David E. Swayne, Mia Kim Torchetti, Hsiang Jung Tsai, Ron A.M. Fouchier, Martin Beer, Mark Woolhouse, Thijs Kuiken, 2016, Science on p. 213-217

Impact of human mobility on the emergence of dengue epidemics in Pakistan

Amy Wesolowski, Taimur Qureshi, Maciej F. Boni, Pål Roe Sundsøy, Michael A. Johansson, Syed Basit Rasheed, Kenth Engø-Monsen, Caroline O. Buckee, Burton H. Singer, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 11887-11892

Recombination within the pandemic norovirus GII.4 lineage

John Sebastian Eden, Mark M. Tanaka, Maciej F. Boni, William D. Rawlinson, Peter A. White, 2013, Journal of Virology on p. 6270-6282

Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

Maciej F. Boni, Philippe Lemey, Xiaowei Jiang, Tommy Tsan Yuk Lam, Blair W. Perry, Todd A. Castoe, Andrew Rambaut, David L. Robertson, 2020, Nature Microbiology on p. 1408-1417

Genomic epidemiology of artemisinin resistant malaria

Roberto Amato, Olivo Miotto, Charles J. Woodrow, Jacob Almagro-Garcia, Ipsita Sinha, Susana Campino, Daniel Mead, Eleanor Drury, Mihir Kekre, Mandy Sanders, Alfred Amambua-Ngwa, Chanaki Amaratunga, Lucas Amenga-Etego, Voahangy Andrianaranjaka, Tobias Apinjoh, Elizabeth Ashley, Sarah Auburn, Gordon A. Awandare, Vito Baraka, Alyssa Barry, Maciej F. Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C. Bull, Kesinee Chotivanich, David J. Conway, Alister Craig, Nicholas P. Day, Abdoulaye Djimdé, Christiane Dolecek, Arjen M. Dondorp, Chris Drakeley, Patrick Duffy, Diego F. Echeverry, Thomas G. Egwang, Rick M. Fairhurst, Abul Faiz, Caterina I. Fanello, Tran Tinh Hien, Abraham Hodgson, Mallika Imwong, Deus Ishengoma, Pharath Lim, Chanthap Lon, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Pascal Michon, Victor Mobegi, 2016, eLife

In vivo susceptibility of plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam

Tran Tinh Hien, Nguyen Thanh Thuy-Nhien, Nguyen Hoan Phu, MacIej F. Boni, Ngo Viet Thanh, Nguyen Thuy Nha-Ca, Le Hong Thai, Cao Quang Thai, Pham Van Toi, Phung Duc Thuan, Le Thanh Long, Le Thanh Dong, Laura Merson, Christiane Dolecek, Kasia Stepniewska, Pascal Ringwald, Nicholas J. White, Jeremy Farrar, Marcel Wolbers, 2012, Malaria Journal

The emergence and evolution of the novel epidemic norovirus GII.4 variant Sydney 2012

John Sebastian Eden, Joanne Hewitt, Kun Lee Lim, Maciej F. Boni, Juan Merif, Gail Greening, Rodney M. Ratcliff, Edward C. Holmes, Mark M. Tanaka, William D. Rawlinson, Peter A. White, 2014, Virology on p. 106-113

Malaria eradication within a generation

Richard G.A. Feachem, Ingrid Chen, Omar Akbari, Amelia Bertozzi-Villa, Samir Bhatt, Fred Binka, Maciej F. Boni, Caroline Buckee, Joseph Dieleman, Arjen Dondorp, Alex Eapen, Neelam Sekhri Feachem, Scott Filler, Peter Gething, Roly Gosling, Annie Haakenstad, Kelly Harvard, Arian Hatefi, Dean Jamison, Kate E. Jones, Corine Karema, Richard Nchabi Kamwi, Altaf Lal, Erika Larson, Margaret Lees, Neil F. Lobo, Angela E. Micah, Bruno Moonen, Gretchen Newby, Xiao Ning, Muhammad Pate, Martha Quiñones, Michelle Roh, Ben Rolfe, Dennis Shanks, Balbir Singh, Kenneth Staley, James Tulloch, Jennifer Wegbreit, Hyun Ju Woo, Winnie Mpanju-Shumbusho, 2019, The Lancet on p. 1056-1112

Genomic analysis of local variation and recent evolution in Plasmodium vivax

Richard D. Pearson, Roberto Amato, Sarah Auburn, Olivo Miotto, Jacob Almagro-Garcia, Chanaki Amaratunga, Seila Suon, Sivanna Mao, Rintis Noviyanti, Hidayat Trimarsanto, Jutta Marfurt, Nicholas M. Anstey, Timothy William, MacIej F. Boni, Christiane Dolecek, Hien Tinh Tran, Nicholas J. White, Pascal Michon, Peter Siba, Livingstone Tavul, Gabrielle Harrison, Alyssa Barry, Ivo Mueller, Marcelo U. Ferreira, Nadira Karunaweera, Milijaona Randrianarivelojosia, Qi Gao, Christina Hubbart, Lee Hart, Ben Jeffery, Eleanor Drury, Daniel Mead, Mihir Kekre, Susana Campino, Magnus Manske, Victoria J. Cornelius, Bronwyn MacInnis, Kirk A. Rockett, Alistair Miles, Julian C. Rayner, Rick M. Fairhurst, Francois Nosten, Ric N. Price, Dominic P. Kwiatkowski, 2016, Nature Genetics on p. 959-964

News Articles Featuring Maciej F Boni

Plenty of Evidence for Recombination in SARS-CoV-2

Different variants of the virus behind the COVID-19 pandemic are swapping chunks of genetic material, but it’s not yet clear what implications that may have for public health.

Experts on WHO team say search for COVID origins has stalled

The international scientists dispatched to China by the World Health Organization to find out where the coronavirus came from said Wednesday the search has stalled and warned that the window of opportunity for solving the mystery is “closing fast.”

China Tells WHO It's Not Nation's Fault Investigation Into COVID-19 Origins Has Stalled

China told the World Health Organization (WHO) on Wednesday that it wasn't the nation's fault that the investigation into the origin of COVID-19 has stalled, the Associated Press reported.

Webinar Alert: Where Did COVID-19 Come From?

The virus that causes COVID-19 disrupted nearly every facet of life for people around the world. The best way to ensure we are prepared for the next pandemic is to understand where the current one started, but that question has become bogged down in geopolitics and conspiracy theories.

Fact Check: The Facts – and Gaps – on the Origin of the Coronavirus

A year and a half into the COVID-19 pandemic — and with a death toll approaching 4 million lives — how the coronavirus came to spark a global scourge remains unknown. Was it the result of a spillover from an animal to a human, as has happened repeatedly in the past? Or did the virus accidentally escape from a nearby lab in Wuhan?

The science around the lab leak theory hasn't changed. But here's why some scientists have.

Five virologists said few conclusions can be drawn based on the available scientific evidence, but they noted that the context and circumstances of the debate have changed.

‘It was just a matter of time’ until coronavirus variant arrived in Centre County amid rising cases

A little over one year after the first coronavirus case was reported in Centre County, a more infectious variant has arrived in the Centre region. The B.1.1.7 variant, also referred to as the United Kingdom variant, was first discovered at Penn State in tested wastewater samples and was confirmed in a “COVID-19 Status Update” with university officials and community leaders on March 26.

Origins of an outbreak

It was late January 2020 when Maciej Boni realized that the COVID-19 pandemic was about to take over his life. Boni, associate professor of biology, is an epidemiologist with extensive expertise in viral evolution, including a recent focus on human and avian flu. When COVID-19 hit, he tapped into a network of colleagues around the world, quickly joining an international team intent on tracking the outbreak to its origins.

The Search for Animals That Could Carry the Next Deadly Virus

Scientists are finding new ways to predict which animals we should be most worried about

Interview with Dr. Maciej Boni