Maciej Boni

Associate Professor of Biology

Maciej Boni

Research Summary

Human influenza epidemiology and evolution, evaluating population-level malaria treatment strategies with individual-based microsimulation models, phylogenetic analysis of avian influenza evolution in southern Vietnam, economic epidemiology of avian influenza, evaluating population-level efficacy of a potential dengue vaccine with mathematical models

Huck Affiliations

Links

Publication Tags

Mutation Sars Virus Population Epidemics Pandemics Climate Viruses Artemisinine Cluster Analysis Genome Antibodies Infections Incidence Norovirus Dengue Southern Africa Panama Severe Acute Respiratory Syndrome Immunity Malaria Genetic Recombination Genes Plasmodium Falciparum South Africa Coronavirus

Most Recent Publications

Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus modelling study

Oliver J. Watson, Bo Gao, Tran Dang Nguyen, Thu Nguyen Anh Tran, Melissa A. Penny, David L. Smith, Lucy Okell, Ricardo Aguas, Maciej F. Boni, 2022, The Lancet Microbe on p. e701-e710

SARS-CoV-2 Attack Rate and Population Immunity in Southern New England, March 2020 to May 2021

Thu Nguyen Anh Tran, Nathan B. Wikle, Fuhan Yang, Haider Inam, Scott Leighow, Bethany Gentilesco, Philip Chan, Emmy Albert, Emily R. Strong, Justin R. Pritchard, William P. Hanage, Ephraim M. Hanks, Forrest W. Crawford, Maciej F. Boni, 2022, JAMA network open on p. E2214171

Mathematical epidemiology for a later age

Noah A. Rosenberg, Maciej F. Boni, 2022, Theoretical Population Biology on p. 81-83

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

Raquel Viana, Sikhulile Moyo, Daniel G. Amoako, Houriiyah Tegally, Cathrine Scheepers, Christian L. Althaus, Ugochukwu J. Anyaneji, Phillip A. Bester, Maciej F. Boni, Mohammed Chand, Wonderful T. Choga, Rachel Colquhoun, Michaela Davids, Koen Deforche, Deelan Doolabh, Louis du Plessis, Susan Engelbrecht, Josie Everatt, Jennifer Giandhari, Marta Giovanetti, Diana Hardie, Verity Hill, Nei Yuan Hsiao, Arash Iranzadeh, Arshad Ismail, Charity Joseph, Rageema Joseph, Legodile Koopile, Sergei L. Kosakovsky Pond, Moritz U.G. Kraemer, Lesego Kuate-Lere, Oluwakemi Laguda-Akingba, Onalethatha Lesetedi-Mafoko, Richard J. Lessells, Shahin Lockman, Alexander G. Lucaci, Arisha Maharaj, Boitshoko Mahlangu, Tongai Maponga, Kamela Mahlakwane, Zinhle Makatini, Gert Marais, Dorcas Maruapula, Kereng Masupu, Mogomotsi Matshaba, Simnikiwe Mayaphi, Nokuzola Mbhele, Mpaphi B. Mbulawa, Adriano Mendes, Koleka Mlisana, Anele Mnguni, Thabo Mohale, Monika Moir, Kgomotso Moruisi, Mosepele Mosepele, Gerald Motsatsi, Modisa S. Motswaledi, Thongbotho Mphoyakgosi, Nokukhanya Msomi, Peter N. Mwangi, Yeshnee Naidoo, Noxolo Ntuli, Martin Nyaga, Lucier Olubayo, Sureshnee Pillay, Botshelo Radibe, Yajna Ramphal, Upasana Ramphal, James E. San, Lesley Scott, Roger Shapiro, Lavanya Singh, Pamela Smith-Lawrence, Wendy Stevens, Amy Strydom, Kathleen Subramoney, Naume Tebeila, Derek Tshiabuila, Joseph Tsui, Stephanie van Wyk, Steven Weaver, Constantinos K. Wibmer, Eduan Wilkinson, Nicole Wolter, Alexander E. Zarebski, Boitumelo Zuze, Dominique Goedhals, Wolfgang Preiser, Florette Treurnicht, Marietje Venter, Carolyn Williamson, Oliver G. Pybus, Jinal Bhiman, Allison Glass, Darren P. Martin, Andrew Rambaut, Simani Gaseitsiwe, Anne von Gottberg, Tulio de Oliveira, 2022, Nature on p. 679-686

Long-term effects of increased adoption of artemisinin combination therapies in Burkina Faso

R Zupko, T Nguyen, F Some, TN-A Tran, J Gerardin, P Dudas, D , A Wesolowski, J-B Ouedraogo, Maciej Boni, 2022, PLoS Global Public Health on p. e0000111

Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function

Darren P. Martin, Spyros Lytras, Alexander G. Lucaci, Wolfgang Maier, Björn Grüning, Stephen D. Shank, Steven Weaver, Oscar A. MacLean, Richard J. Orton, Philippe Lemey, MacIej F. Boni, Houriiyah Tegally, Gordon W. Harkins, Cathrine Scheepers, Jinal N. Bhiman, Josie Everatt, Daniel G. Amoako, James Emmanuel San, Jennifer Giandhari, Alex Sigal, Carolyn Williamson, Nei Yuan Hsiao, Anne Von Gottberg, Arne De Klerk, Robert W. Shafer, David L. Robertson, Robert J. Wilkinson, B. Trevor Sewell, Richard Lessells, Anton Nekrutenko, Allison J. Greaney, Tyler N. Starr, Jesse D. Bloom, Ben Murrell, Eduan Wilkinson, Ravindra K. Gupta, Tulio De Oliveira, Sergei L.Kosakovsky Pond, 2022, Molecular Biology and Evolution

SARS-CoV-2 epidemic after social and economic reopening in three U.S. states reveals shifts in age structure and clinical characteristics

Nathan B. Wikle, Thu Tran, Thu Nguyen-Anh Tran, Emily Strong, Bethany Gentilesco, Ephraim Hanks, Scott M. Leighow, Emmy Albert, Emily R. Strong, Karel Brinda, Haider Inam, Fuhan Yang, Sajid Hossain, Philip Chan, William P. Hanage, Maria Messick, Justin R. Pritchard, Maciej F. Boni, 2022, Science advances on p. eabf9868

Age-seroprevalence curves for the multi-strain structure of influenza A virus

Dao Nguyen Vinh, Nguyen Thi Duy Nhat, Erwin de Bruin, Nguyen Ha Thao Vy, Tran Thi Nhu Thao, Huynh Thi Phuong, Pham Hong Anh, Stacy Todd, Tran Minh Quan, Nguyen Thi Le Thanh, Nguyen Thi Nam Lien, Nguyen Thi Hong Ha, Tran Thi Kim Hong, Pham Quang Thai, Marc Choisy, Tran Dang Nguyen, Cameron P. Simmons, Guy E. Thwaites, Hannah E. Clapham, Nguyen Van Vinh Chau, Marion Koopmans, Maciej F. Boni, 2021, Nature Communications

Assessing the effect of climate variables on the incidence of dengue cases in the metropolitan region of panama city

Vicente Navarro Valencia, Yamilka Díaz, Juan Miguel Pascale, Maciej F. Boni, Javier E. Sanchez-Galan, 2021, International Journal of Environmental Research and Public Health

Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic

Ben Jackson, Maciej F. Boni, Matthew J. Bull, Amy Colleran, Rachel M. Colquhoun, Alistair C. Darby, Sam Haldenby, Verity Hill, Anita Lucaci, John T. McCrone, Samuel M. Nicholls, Áine O'Toole, Nicole Pacchiarini, Radoslaw Poplawski, Emily Scher, Flora Todd, Hermione J. Webster, Mark Whitehead, Claudia Wierzbicki, Nicholas J. Loman, Thomas R. Connor, David L. Robertson, Oliver G. Pybus, Andrew Rambaut, 2021, Cell on p. 5179-5188.e8

Most-Cited Papers

Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

Maciej F. Boni, Philippe Lemey, Xiaowei Jiang, Tommy Tsan Yuk Lam, Blair W. Perry, Todd A. Castoe, Andrew Rambaut, David L. Robertson, 2020, Nature Microbiology on p. 1408-1417

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

Raquel Viana, Sikhulile Moyo, Daniel G. Amoako, Houriiyah Tegally, Cathrine Scheepers, Christian L. Althaus, Ugochukwu J. Anyaneji, Phillip A. Bester, Maciej F. Boni, Mohammed Chand, Wonderful T. Choga, Rachel Colquhoun, Michaela Davids, Koen Deforche, Deelan Doolabh, Louis du Plessis, Susan Engelbrecht, Josie Everatt, Jennifer Giandhari, Marta Giovanetti, Diana Hardie, Verity Hill, Nei Yuan Hsiao, Arash Iranzadeh, Arshad Ismail, Charity Joseph, Rageema Joseph, Legodile Koopile, Sergei L. Kosakovsky Pond, Moritz U.G. Kraemer, Lesego Kuate-Lere, Oluwakemi Laguda-Akingba, Onalethatha Lesetedi-Mafoko, Richard J. Lessells, Shahin Lockman, Alexander G. Lucaci, Arisha Maharaj, Boitshoko Mahlangu, Tongai Maponga, Kamela Mahlakwane, Zinhle Makatini, Gert Marais, Dorcas Maruapula, Kereng Masupu, Mogomotsi Matshaba, Simnikiwe Mayaphi, Nokuzola Mbhele, Mpaphi B. Mbulawa, Adriano Mendes, Koleka Mlisana, Anele Mnguni, Thabo Mohale, Monika Moir, Kgomotso Moruisi, Mosepele Mosepele, Gerald Motsatsi, Modisa S. Motswaledi, Thongbotho Mphoyakgosi, Nokukhanya Msomi, Peter N. Mwangi, Yeshnee Naidoo, Noxolo Ntuli, Martin Nyaga, Lucier Olubayo, Sureshnee Pillay, Botshelo Radibe, Yajna Ramphal, Upasana Ramphal, James E. San, Lesley Scott, Roger Shapiro, Lavanya Singh, Pamela Smith-Lawrence, Wendy Stevens, Amy Strydom, Kathleen Subramoney, Naume Tebeila, Derek Tshiabuila, Joseph Tsui, Stephanie van Wyk, Steven Weaver, Constantinos K. Wibmer, Eduan Wilkinson, Nicole Wolter, Alexander E. Zarebski, Boitumelo Zuze, Dominique Goedhals, Wolfgang Preiser, Florette Treurnicht, Marietje Venter, Carolyn Williamson, Oliver G. Pybus, Jinal Bhiman, Allison Glass, Darren P. Martin, Andrew Rambaut, Simani Gaseitsiwe, Anne von Gottberg, Tulio de Oliveira, 2022, Nature on p. 679-686

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Olivo Miotto, Jacob Almagro-Garcia, Magnus Manske, Bronwyn MacInnis, Susana Campino, Kirk A. Rockett, Chanaki Amaratunga, Pharath Lim, Seila Suon, Sokunthea Sreng, Jennifer M. Anderson, Socheat Duong, Chea Nguon, Char Meng Chuor, David Saunders, Youry Se, Chantap Lon, Mark M. Fukuda, Lucas Amenga-Etego, Abraham V.O. Hodgson, Victor Asoala, Mallika Imwong, Shannon Takala-Harrison, François Nosten, Xin Zhuan Su, Pascal Ringwald, Frédéric Ariey, Christiane Dolecek, Tran Tinh Hien, Maciej F. Boni, Cao Quang Thai, Alfred Amambua-Ngwa, David J. Conway, Abdoulaye A. Djimdé, Ogobara K. Doumbo, Issaka Zongo, Jean Bosco Ouedraogo, Daniel Alcock, Eleanor Drury, Sarah Auburn, Oliver Koch, Mandy Sanders, Christina Hubbart, Gareth Maslen, Valentin Ruano-Rubio, Dushyanth Jyothi, Alistair Miles, John O'Brien, Chris Gamble, Samuel O. Oyola, Julian C. Rayner, Chris I. Newbold, Matthew Berriman, Chris C.A. Spencer, Gilean McVean, Nicholas P. Day, Nicholas J. White, Delia Bethell, Arjen M. Dondorp, Christopher V. Plowe, Rick M. Fairhurst, Dominic P. Kwiatkowski, 2013, Nature Genetics on p. 648-655

Role for migratory wild birds in the global spread of avian influenza H5N8

Samantha Lycett, Rogier Bodewes, Anne Pohlmann, Jill Banks, Krisztián Bányai, Maciej Boni, Ruth Bouwstra, Andrew Breed, Ian Brown, Hualan Chen, Ádám Dán, Thomas DeLiberto, Nguyen Diep, Marius Gilbert, Sarah Hill, Hon Ip, Chang Ke, Hiroshi Kida, Mary Killian, Marion Koopmans, Jung Kwon, Dong Lee, Youn Lee, Lu Lu, Isabella Monne, John Pasick, Oliver Pybus, Andrew Rambaut, Timothy Robinson, Yoshihiro Sakoda, Siamak Zohari, Chang Song, David Swayne, Mia Torchetti, Hsiang Tsai, Ron Fouchier, Martin Beer, Mark Woolhouse, Thijs Kuiken, 2016, Science on p. 213-217

Impact of human mobility on the emergence of dengue epidemics in Pakistan

Amy Wesolowski, Taimur Qureshi, Maciej F. Boni, Pål Roe Sundsøy, Michael A. Johansson, Syed Basit Rasheed, Kenth Engø-Monsen, Caroline O. Buckee, Burton H. Singer, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 11887-11892

Recombination within the pandemic norovirus GII.4 lineage

John Sebastian Eden, Mark M. Tanaka, Maciej F. Boni, William D. Rawlinson, Peter A. White, 2013, Journal of Virology on p. 6270-6282

Genomic epidemiology of artemisinin resistant malaria

Roberto Amato, Olivo Miotto, Charles Woodrow, Jacob Almagro-Garcia, Ipsita Sinha, Susana Campino, Daniel Mead, Eleanor Drury, Mihir Kekre, Mandy Sanders, Alfred Amambua-Ngwa, Chanaki Amaratunga, Lucas Amenga-Etego, Voahangy Andrianaranjaka, Tobias Apinjoh, Elizabeth Ashley, Sarah Auburn, Gordon Awandare, Vito Baraka, Alyssa Barry, Maciej Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter Bull, Kesinee Chotivanich, David Conway, Alister Craig, Nicholas Day, Abdoulaye Djimdé, Christiane Dolecek, Arjen Dondorp, Chris Drakeley, Patrick Duffy, Diego Echeverry, Thomas Egwang, Rick Fairhurst, Abul Faiz, Caterina Fanello, Tran Hien, Abraham Hodgson, Mallika Imwong, Deus Ishengoma, Pharath Lim, Chanthap Lon, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Pascal Michon, Victor Mobegi, Olugbenga Mokuolu, Jacqui Montgomery, Ivo Mueller, Myat Kyaw, Paul Newton, Francois Nosten, Rintis Noviyanti, Alexis Nzila, Harold Ocholla, Abraham Oduro, Marie Onyamboko, Jean Ouedraogo, Aung Phyo, Christopher Plowe, Ric Price, Sasithon Pukrittayakamee, Milijaona Randrianarivelojosia, Pascal Ringwald, Lastenia Ruiz, David Saunders, Alex Shayo, Peter Siba, Shannon Takala-Harrison, Thuy Thanh, Vandana Thathy, Federica Verra, Jason Wendler, Nicholas White, Htut Ye, Victoria Cornelius, Rachel Giacomantonio, Dawn Muddyman, Christa Henrichs, Cinzia Malangone, Dushyanth Jyothi, Richard Pearson, Julian Rayner, Gilean McVean, Kirk Rockett, Alistair Miles, Paul Vauterin, Ben Jeffery, Magnus Manske, Jim Stalker, Bronwyn Macinnis, Dominic Kwiatkowski, 2016, eLife

Malaria eradication within a generation: ambitious, achievable, and necessary

Richard G.A. Feachem, Ingrid Chen, Omar Akbari, Amelia Bertozzi-Villa, Samir Bhatt, Fred Binka, Maciej F. Boni, Caroline Buckee, Joseph Dieleman, Arjen Dondorp, Alex Eapen, Neelam Sekhri Feachem, Scott Filler, Peter Gething, Roly Gosling, Annie Haakenstad, Kelly Harvard, Arian Hatefi, Dean Jamison, Kate E. Jones, Corine Karema, Richard Nchabi Kamwi, Altaf Lal, Erika Larson, Margaret Lees, Neil F. Lobo, Angela E. Micah, Bruno Moonen, Gretchen Newby, Xiao Ning, Muhammad Pate, Martha Quiñones, Michelle Roh, Ben Rolfe, Dennis Shanks, Balbir Singh, Kenneth Staley, James Tulloch, Jennifer Wegbreit, Hyun Ju Woo, Winnie Mpanju-Shumbusho, 2019, The Lancet on p. 1056-1112

The origins of SARS-CoV-2: A critical review

E Holmes, S Goldstein, A Rasmussen, D Robertson, A Crits-Christoph, J Wertheim, S Anthony, W Barclay, Maciej Boni, P Doherty, J Farrar, J Geoghegan, X Jiang, J Leibowitz, Neil SJD, T Skern, S Weiss, M Worobey, K Andersen, R Garry, A Rambaut, 2021, Cell on p. 4848-4856

Genomic analysis of local variation and recent evolution in Plasmodium vivax

R Pearson, R Amato, S Auburn, O Miotto, J Almagro-Garcia, C Amaratunga, S Suon, S Mao, R Noviyanti, H Trimarsanto, J Marfurt, N Anstey, T William, Maciej Boni, C Dolecek, Hien Tinh Tran, T Hien, N White, P Michon, P Siba, L Tavul, G Harrison, A Barry, I Mueller, M Ferreira, N Karunaweera, M Randrianarivelojosia, Q Gao, C Hubbart, L Hart, B Jeffery, E Drury, D Mead, M Kekre, S Campino, M Manske, V Cornelius, B MacInnis, K Rockett, A Miles, J Rayner, R Fairhurst, F Nosten, R Price, D Kwiatkowski, 2016, Nature Genetics on p. 959-964