Leslie Parent
Professor of Medicine and Microbiology & Immunology
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H175 Hershey Medical Center
Hershey, PA - ljp5@psu.edu
- 717-531-7199
Huck Affiliations
Publication Tags
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Hiv 1 Rna Retroviridae Proteins Rous Sarcoma Virus Coronavirus Gag Gene Products Sars Virus Viral Rna Nucleic Acids Therapeutics Pharmaceutical Preparations Cohort Studies Infections Product Packaging Mouse Mammary Tumor Virus Mortality Systematic Reviews Odds Ratio Virus Assembly Meta Analysis Vaccines Retrospective Studies Virion Glucagon Like Peptide 1 ReceptorMost Recent Publications
Influence of HIV-1 Genomic RNA on the Formation of Gag Biomolecular Condensates
Anne Monette, Meijuan Niu, Rebecca Kaddis Maldonado, Jordan Chang, Gregory S. Lambert, John M. Flanagan, Alan Cochrane, Leslie J. Parent, Andrew J. Mouland, 2023, Journal of Molecular Biology
The Rous sarcoma virus Gag Polyprotein Forms Biomolecular Condensates Driven by Intrinsically-disordered Regions
Rebecca Kaddis Maldonado, Gregory S. Lambert, Breanna L. Rice, Malgorzata Sudol, John M. Flanagan, Leslie J. Parent, 2023, Journal of Molecular Biology
Virus Induced Membraneless Organelles and Biomolecular Condensates
Andrew J. Mouland, Leslie Parent, Stephanie C. Weber, Alex S. Holehouse, 2023, Journal of Molecular Biology
Liquid-liquid phase separation of nucleocapsid proteins during SARS-CoV-2 and HIV-1 replication
Bao An Chau, Venessa Chen, Alan W. Cochrane, Leslie J. Parent, Andrew J. Mouland, 2023, Cell Reports
SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19: a systematic review and meta-analysis
Paddy Ssentongo, Anna E. Ssentongo, Navya Voleti, Destin Groff, Ashley Sun, Djibril M. Ba, Jonathan Nunez, Leslie J. Parent, Vernon M. Chinchilli, Catharine I. Paules, 2022, BMC Infectious Diseases
Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency
Subha Dahal, Kiera Clayton, Terek Been, Raphaële Fernet-Brochu, Alonso Villasmil Ocando, Ahalya Balachandran, Mikaël Poirier, Rebecca Kaddis Maldonado, Lulzim Shkreta, Kayluz Frias Boligan, Furkan Guvenc, Fariha Rahman, Donald Branch, Brendan Bell, Benoit Chabot, Scott D. Gray-Owen, Leslie J. Parent, Alan Cochrane, 2022, Retrovirology
Clinician-Scientist Faculty Mentoring Program (FAME) – A New Inclusive Training Model at Penn State Increases Scholarly Productivity and Extramural Grant Funding
Sinisa Dovat, Chandrika Gowda, Richard B. Mailman, Leslie J. Parent, Xuemei Huang, 2022, Advances in Medical Education and Practice on p. 1039-1050
Diabetes, Drug Treatment, and Mortality in COVID-19: A Multinational Retrospective Cohort Study
Jennifer Nyland, N Raja-Khan, K Bettermann, P Haouzi, J Kraschnewski, L Parent, P Grigson, 2021, Diabetes on p. 2903-2916
Monoclonal antibodies to s and n sars-cov-2 proteins as probes to assess structural and antigenic properties of coronaviruses
R Kumar, Neil D. Christensen, R Kaddis Maldonado, Maria C. Bewley, A Ostman, M Sudol, E Chen, N Buchkovich, A Gontu, Meera Surendran Nair, R Nissly, A Minns, Vivek Kapur, R Rossi, Suresh V. Kuchipudi, Scott E. Lindner, Leslie J. Parent, John M. Flanagan, Nicholas J. Buchkovich, 2021, Viruses
Visualizing rous sarcoma virus genomic rna dimerization in the nucleus, cytoplasm, and at the plasma membrane
Eunice C. Chen, Rebecca J. Kaddis Maldonado, Leslie J. Parent, 2021, Viruses
Most-Cited Papers
SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19: a systematic review and meta-analysis
Paddy Ssentongo, Anna E. Ssentongo, Navya Voleti, Destin Groff, Ashley Sun, Djibril M. Ba, Jonathan Nunez, Leslie J. Parent, Vernon M. Chinchilli, Catharine I. Paules, 2022, BMC Infectious Diseases
Diabetes, Drug Treatment, and Mortality in COVID-19: A Multinational Retrospective Cohort Study
Jennifer Nyland, N Raja-Khan, K Bettermann, P Haouzi, J Kraschnewski, L Parent, P Grigson, 2021, Diabetes on p. 2903-2916
Orchestrating the selection and packaging of genomic RNA by retroviruses: An ensemble of viral and host factors
Rebecca J. Kaddis Maldonado, Leslie J. Parent, 2016, Viruses
HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins
Matthew Stake, Deepali Singh, Gatikrushna Singh, J. Marcela Hernandez, Rebecca Kaddis Maldonado, Leslie J. Parent, Kathleen Boris-Lawrie, 2015, Virology on p. 307-320
Visualizing association of the retroviral gag protein with unspliced viral RNA in the nucleus
Rebecca J.Kaddis Maldonado, Breanna Rice, Eunice C. Chen, Kevin M. Tuffy, Estelle F. Chiari, Kelly M. Fahrbach, Thomas J. Hope, Leslie J. Parent, 2020, mBio
Hiv-1 gag forms ribonucleoprotein complexes with unspliced viral rna at transcription sites
Kevin M. Tuffy, Rebecca J. Kaddis Maldonado, Jordan Chang, Paul Rosenfeld, Alan Cochrane, Leslie J. Parent, 2020, Viruses
Functional equivalence of retroviral MA domains in facilitating Psi RNA binding specificity by Gag
Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2016, Viruses
A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55<sup>Gag</sup> polyprotein alters nucleic acid binding properties
Maria C. Bewley, Lisa Reinhart, Matthew S. Stake, Shorena Nadaraia-Hoke, Leslie J. Parent, John M. Flanagan, 2017, Protein Expression and Purification on p. 137-145
Mechanistic differences between nucleic acid chaperone activities of the gag proteins of rous sarcoma virus and human immunodeficiency virus type 1 are attributed to the MA domain
Tiffiny D. Rye-McCurdy, Shorena Nadaraia-Hoke, Nicole Gudleski-O'Regan, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2014, Journal of Virology on p. 7852-7861
A murine retrovirus Co-Opts YB-1, a translational regulator and stress granule-associated protein, to facilitate virus assembly
Darrin V. Bann, Andrea R. Beyer, Leslie J. Parent, 2014, Journal of Virology on p. 4434-4450