Leslie Parent
Professor of Medicine and Microbiology & Immunology
- H175 Hershey Medical Center
Hershey, PA - ljp5@psu.edu
- 717-531-7199
Huck Institutes Affiliations
Publication Tags
Rous Sarcoma Virus Gag Gene Products Proteins Rna Hiv 1 Mouse Mammary Tumor Virus Viral Rna Nucleic Acids Retroviridae Product Packaging Virion Cell Membrane Virus Assembly Nucleocapsid Phosphatidylinositols Cell Nucleolus Plasma Membrane 5' Untranslated Regions Capsid Viruses Human Immunodeficiency Virus 1 Chickens Ribosomal Protein L9 Ribosomal Proteins Rna Binding ProteinsMost Recent Papers
A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55<sup>Gag</sup> polyprotein alters nucleic acid binding properties
Maria C. Bewley, Lisa Reinhart, Matthew S. Stake, Shorena Nadaraia-Hoke, Leslie J. Parent, John M. Flanagan, 2017, Protein Expression and Purification on p. 137-145
Functional equivalence of retroviral MA domains in facilitating Psi RNA binding specificity by Gag
Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2016, Viruses
HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins
Matthew Stake, Deepali Singh, Gatikrushna Singh, J. Marcela Hernandez, Rebecca Kaddis Maldonado, Leslie J. Parent, Kathleen Boris-Lawrie, 2015, Virology on p. 307-320
Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus
Breanna L. Rice, Rebecca J. Kaddis, Matthew S. Stake, Timothy L. Lochmann, Leslie J. Parent, 2015, Frontiers in Microbiology
A murine retrovirus Co-Opts YB-1, a translational regulator and stress granule-associated protein, to facilitate virus assembly
Darrin V. Bann, Andrea R. Beyer, Leslie J. Parent, 2014, Journal of virology on p. 4434-4450
Mechanistic differences between nucleic acid chaperone activities of the gag proteins of rous sarcoma virus and human immunodeficiency virus type 1 are attributed to the MA domain
Tiffiny D. Rye-McCurdy, Shorena Nadaraia-Hoke, Nicole Gudleski-O'Regan, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2014, Journal of virology on p. 7852-7861
Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs
Joseph A. Webb, Christopher P. Jones, Leslie J. Parent, Ioulia Rouzina, Karin Musier-Forsyth, 2013, RNA on p. 1078-1088
Alterations in the MA and NC domains modulate phosphoinositide-dependent plasma membrane localization of the Rous sarcoma virus gag protein
Shorena Nadaraia-Hoke, Darrin V. Bann, Timothy L. Lochmann, Nicole Gudleski-O'Regan, Leslie J. Parent, 2013, Journal of Virology on p. 3609-3615
NC-mediated nucleolar localization of retroviral gag proteins.
Timothy L. Lochmann, Darrin V. Bann, Eileen P. Ryan, Andrea R. Beyer, Annie Mao, Alan Cochrane, Leslie Parent, 2013, Unknown Journal on p. 304-318
Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9
Andrea R. Beyer, Darrin V. Bann, Breanna Rice, Ingrid S. Pultz, Melissa Kane, Stephen P. Goff, Tatyana V. Golovkina, Leslie J. Parent, 2013, Journal of Virology on p. 1069-1082
High-Impact Papers
Genetic evidence for a connection between Rous sarcoma virus Gag nuclear trafficking and genomic RNA packaging
Rachel Garbitt-Hirst, Scott P. Kenney, Leslie J. Parent, 2009, Journal of virology on p. 6790-6797
Directionality of nucleocytoplasmic transport of the retroviral gag protein depends on sequential binding of karyopherins and viral RNA
Nicole Gudleski, John M. Flanagan, Eileen P. Ryan, Maria C. Bewley, Leslie J. Parent, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 9358-9363
Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs
Joseph A. Webb, Christopher P. Jones, Leslie J. Parent, Ioulia Rouzina, Karin Musier-Forsyth, 2013, RNA on p. 1078-1088
Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9
Andrea R. Beyer, Darrin V. Bann, Breanna Rice, Ingrid S. Pultz, Melissa Kane, Stephen P. Goff, Tatyana V. Golovkina, Leslie J. Parent, 2013, Journal of Virology on p. 1069-1082
New insights into the nuclear localization of retroviral gag proteins
Leslie J. Parent, 2011, Nucleus
NC-mediated nucleolar localization of retroviral gag proteins.
Timothy L. Lochmann, Darrin V. Bann, Eileen P. Ryan, Andrea R. Beyer, Annie Mao, Alan Cochrane, Leslie Parent, 2013, Unknown Journal on p. 304-318
Alterations in the MA and NC domains modulate phosphoinositide-dependent plasma membrane localization of the Rous sarcoma virus gag protein
Shorena Nadaraia-Hoke, Darrin V. Bann, Timothy L. Lochmann, Nicole Gudleski-O'Regan, Leslie J. Parent, 2013, Journal of Virology on p. 3609-3615
Mechanistic differences between nucleic acid chaperone activities of the gag proteins of rous sarcoma virus and human immunodeficiency virus type 1 are attributed to the MA domain
Tiffiny D. Rye-McCurdy, Shorena Nadaraia-Hoke, Nicole Gudleski-O'Regan, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2014, Journal of virology on p. 7852-7861
Functional equivalence of retroviral MA domains in facilitating Psi RNA binding specificity by Gag
Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2016, Viruses
HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins
Matthew Stake, Deepali Singh, Gatikrushna Singh, J. Marcela Hernandez, Rebecca Kaddis Maldonado, Leslie J. Parent, Kathleen Boris-Lawrie, 2015, Virology on p. 307-320