Leslie Parent

Professor of Medicine and Microbiology & Immunology

Leslie Parent

Huck Affiliations

Publication Tags

Rous Sarcoma Virus Gag Gene Products Proteins Rna Hiv 1 Mouse Mammary Tumor Virus Viral Rna Nucleic Acids Retroviridae Product Packaging Virion Cell Membrane Virus Assembly Nucleocapsid Phosphatidylinositols Cell Nucleolus Plasma Membrane 5' Untranslated Regions Capsid Viruses Human Immunodeficiency Virus 1 Chickens Ribosomal Protein L9 Ribosomal Proteins Rna Binding Proteins

Most Recent Papers

A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55<sup>Gag</sup> polyprotein alters nucleic acid binding properties

Maria C. Bewley, Lisa Reinhart, Matthew S. Stake, Shorena Nadaraia-Hoke, Leslie J. Parent, John M. Flanagan, 2017, Protein Expression and Purification on p. 137-145

Functional equivalence of retroviral MA domains in facilitating Psi RNA binding specificity by Gag

Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2016, Viruses

HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins

Matthew Stake, Deepali Singh, Gatikrushna Singh, J. Marcela Hernandez, Rebecca Kaddis Maldonado, Leslie J. Parent, Kathleen Boris-Lawrie, 2015, Virology on p. 307-320

Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus

Breanna L. Rice, Rebecca J. Kaddis, Matthew S. Stake, Timothy L. Lochmann, Leslie J. Parent, 2015, Frontiers in Microbiology

A murine retrovirus Co-Opts YB-1, a translational regulator and stress granule-associated protein, to facilitate virus assembly

Darrin V. Bann, Andrea R. Beyer, Leslie J. Parent, 2014, Journal of virology on p. 4434-4450

Mechanistic differences between nucleic acid chaperone activities of the gag proteins of rous sarcoma virus and human immunodeficiency virus type 1 are attributed to the MA domain

Tiffiny D. Rye-McCurdy, Shorena Nadaraia-Hoke, Nicole Gudleski-O'Regan, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2014, Journal of virology on p. 7852-7861

Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs

Joseph A. Webb, Christopher P. Jones, Leslie J. Parent, Ioulia Rouzina, Karin Musier-Forsyth, 2013, RNA on p. 1078-1088

Alterations in the MA and NC domains modulate phosphoinositide-dependent plasma membrane localization of the Rous sarcoma virus gag protein

Shorena Nadaraia-Hoke, Darrin V. Bann, Timothy L. Lochmann, Nicole Gudleski-O'Regan, Leslie J. Parent, 2013, Journal of Virology on p. 3609-3615

NC-mediated nucleolar localization of retroviral gag proteins.

Timothy L. Lochmann, Darrin V. Bann, Eileen P. Ryan, Andrea R. Beyer, Annie Mao, Alan Cochrane, Leslie Parent, 2013, Unknown Journal on p. 304-318

Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9

Andrea R. Beyer, Darrin V. Bann, Breanna Rice, Ingrid S. Pultz, Melissa Kane, Stephen P. Goff, Tatyana V. Golovkina, Leslie J. Parent, 2013, Journal of Virology on p. 1069-1082

High-Impact Papers

Genetic evidence for a connection between Rous sarcoma virus Gag nuclear trafficking and genomic RNA packaging

Rachel Garbitt-Hirst, Scott P. Kenney, Leslie J. Parent, 2009, Journal of virology on p. 6790-6797

Directionality of nucleocytoplasmic transport of the retroviral gag protein depends on sequential binding of karyopherins and viral RNA

Nicole Gudleski, John M. Flanagan, Eileen P. Ryan, Maria C. Bewley, Leslie J. Parent, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 9358-9363

Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs

Joseph A. Webb, Christopher P. Jones, Leslie J. Parent, Ioulia Rouzina, Karin Musier-Forsyth, 2013, RNA on p. 1078-1088

Nucleolar trafficking of the mouse mammary tumor virus gag protein induced by interaction with ribosomal protein L9

Andrea R. Beyer, Darrin V. Bann, Breanna Rice, Ingrid S. Pultz, Melissa Kane, Stephen P. Goff, Tatyana V. Golovkina, Leslie J. Parent, 2013, Journal of Virology on p. 1069-1082

New insights into the nuclear localization of retroviral gag proteins

Leslie J. Parent, 2011, Nucleus

NC-mediated nucleolar localization of retroviral gag proteins.

Timothy L. Lochmann, Darrin V. Bann, Eileen P. Ryan, Andrea R. Beyer, Annie Mao, Alan Cochrane, Leslie Parent, 2013, Unknown Journal on p. 304-318

Alterations in the MA and NC domains modulate phosphoinositide-dependent plasma membrane localization of the Rous sarcoma virus gag protein

Shorena Nadaraia-Hoke, Darrin V. Bann, Timothy L. Lochmann, Nicole Gudleski-O'Regan, Leslie J. Parent, 2013, Journal of Virology on p. 3609-3615

Mechanistic differences between nucleic acid chaperone activities of the gag proteins of rous sarcoma virus and human immunodeficiency virus type 1 are attributed to the MA domain

Tiffiny D. Rye-McCurdy, Shorena Nadaraia-Hoke, Nicole Gudleski-O'Regan, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2014, Journal of virology on p. 7852-7861

Functional equivalence of retroviral MA domains in facilitating Psi RNA binding specificity by Gag

Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth, 2016, Viruses

HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins

Matthew Stake, Deepali Singh, Gatikrushna Singh, J. Marcela Hernandez, Rebecca Kaddis Maldonado, Leslie J. Parent, Kathleen Boris-Lawrie, 2015, Virology on p. 307-320