Kurt Vandegrift

Associate Professor

Research Summary

Disease ecology with an emphasis on the population dynamics of zoonotic parasites and reservoir hosts.

Huck Affiliations

Links

Publication Tags

Ecology Viruses Severe Acute Respiratory Syndrome Coronavirus Surveillance Ticks Parasites Reuse Public Health Metadata Infectious Diseases Oxyurida Avian Influenza Amino Acids Cattle Deer Human Influenza Pest Viral Load Hepacivirus Nematoda Angiotensin Converting Enzyme 2 Thogotovirus Hydrogen Cattle Diseases

Most Recent Papers

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

Suresh V. Kuchipudi, Meera Surendran-Nair, Rachel M. Ruden, Michele Yon, Ruth H. Nissly, Kurt J. Vandegrift, Rahul K. Nelli, Lingling Li, Bhushan M. Jayarao, Costas D. Maranas, Nicole Levine, Katriina Willgert, Andrew J.K. Conlan, Randall J. Olsen, James J. Davis, James M. Musser, Peter John Hudson, Vivek Kapur, 2022, Proceedings of the National Academy of Sciences of the United States of America

Detection of SARS-CoV-2 Omicron variant (B.1.1.529) infection of white-tailed deer.

Kurt Vandegrift, M Yon, M Surendran-Nair, A Gontu, S Amirthalingam, R Nissly, N Levine, T Stuber, A DeNicola, J Boulanger, N Kotschwar, S Aucoin, R Simon, K Toal, R Olsen, J Davis, D Bold, N Gaudreault, J Richt, J Musser, P Hudson, V Kapur, S Kuchipudi, 2022, bioRxiv : the preprint server for biology

A molecular reconstruction of holarctic Heligmosomidae reveals a new species of Heligmosomoides (Nematoda

Haitham Alnaqeb, Stephen E. Greiman, Kurt J. Vandegrift, Mariel L. Campbell, Shawn Meagher, F. Agustín Jiménez, 2022, Systematics and Biodiversity on p. 1-19

Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2

Chen Chen, Veda Sheersh Boorla, Deepro Banerjee, Ratul Chowdhury, Victoria S. Cavener, Ruth H. Nissly, Abhinay Gontu, Nina R. Boyle, Kurt Vandegrift, Meera Surendran Nair, Suresh V. Kuchipudi, Costas D. Maranas, 2021, Proceedings of the National Academy of Sciences of the United States of America

Species-Level Profiling of Ixodes pacificus Bacterial Microbiomes Reveals High Variability across Short Spatial Scales at Different Taxonomic Resolutions

Kayla M. Socarras, Joshua P. Earl, Jaroslaw E. Krol, Archana Bhat, Max Pabilonia, Meghan H. Harrison, Steven P. Lang, Bhaswati Sen, Azad Ahmed, Michael Hester, Joshua Chang Mell, Kurt Vandegrift, Garth D. Ehrlich, 2021, Genetic Testing on p. 551-562

Rodent virus diversity and differentiation across post-katrina new orleans

Anna C. Peterson, Himanshu Sharma, Arvind Kumar, Bruno M. Ghersi, Scott J. Emrich, Kurt J. Vandegrift, Amit Kapoor, Michael J. Blum, 2021, Sustainability (Switzerland)

Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD): Emerging role of orthomyxoviruses in the pathogenesis of BRD

Ruth Nissly, Noriza Zaman, Ibrahim, Puteri Ainaa S., Puteri Ainaa S. Ibrahim, Ibrahim PAS, Kaitlin McDaniel, Levina Lim, Jennifer Kiser, Ian Bird, Shubhada Chothe, Gitanjali Bhushan, Kurt Vandegrift, Holly Neibergs, Kuchipudi, Suresh, V, Suresh V. Kuchipudi, 2020, Virology on p. 10-15

Presence of segmented flavivirus infections in North America

Kurt Vandegrift, Arvind Kumar, Himanshu Sharma, Satyapramod Murthy, Laura Kramer, Richard Ostfeld, Peter Hudson, Amit Kapoor, 2020, Emerging Infectious Diseases on p. 1810-1817

The ecology of new constituents of the tick virome and their relevance to public health

Kurt J. Vandegrift, Amit Kapoor, 2019, Viruses

MIReAD, a minimum information standard for reporting arthropod abundance data

Samuel S.C. Rund, Kyle Braak, Lauren Cator, Kyle Copas, Scott J. Emrich, Gloria I. Giraldo-Calderón, Michael A. Johansson, Naveed Heydari, Donald Hobern, Sarah A. Kelly, Daniel Lawson, Cynthia Lord, Robert M. MacCallum, Dominique G. Roche, Sadie J. Ryan, Dmitry Schigel, Kurt Vandegrift, Matthew Watts, Jennifer M. Zaspel, Samraat Pawar, 2019, Scientific data

Most-Cited Papers

Identification of rodent homologs of hepatitis C virus and pegiviruses

Amit Kapoor, Peter Simmonds, Troels K.H. Scheel, Brian Hjelle, John M. Cullen, Peter D. Burbelo, Lokendra V. Chauhan, Raja Duraisamy, Maria Sanchez Leon, Komal Jain, Kurt Jason Vandegrift, Charles H. Calisher, Charles M. Rice, W. Ian Lipkin, 2013, mBio

Towards an eco-phylogenetic framework for infectious disease ecology

Nicholas M. Fountain-Jones, William D. Pearse, Luis E. Escobar, Ana Alba-Casals, Scott Carver, T. Jonathan Davies, Simona Kraberger, Monica Papeş, Kurt Vandegrift, Katherine Worsley-Tonks, Meggan E. Craft, 2018, Biological Reviews on p. 950-970

Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model

Sheetal Trivedi, Satyapramod Murthy, Himanshu Sharma, Alex S. Hartlage, Arvind Kumar, Sashi V. Gadi, Peter Simmonds, Lokendra V. Chauhan, Troels K.H. Scheel, Eva Billerbeck, Peter D. Burbelo, Charles M. Rice, W. Ian Lipkin, Kurt Vandegrift, John M. Cullen, Amit Kapoor, 2018, Hepatology on p. 435-448

The ecology of new constituents of the tick virome and their relevance to public health

Kurt J. Vandegrift, Amit Kapoor, 2019, Viruses

Bank voles (Myodes glareolus) and house mice (Mus musculus musculus; M. m. domesticus) in Europe are each parasitized by their own distinct species of Aspiculuris (Nematoda, Oxyurida)

J. M. Behnke, A. Stewart, A. Bajer, M. Grzybek, P. D. Harris, A. Lowe, A. Ribas, L. Smales, Kurt Vandegrift, 2015, Parasitology on p. 1493-1505

Bird migration and avian influenza

Eli S. Bridge, Jeffrey F. Kelly, Xiangming Xiao, John Y. Takekawa, Nichola J. Hill, Mat Yamage, Enam Ul Haque, Mohammad Anwarul Islam, Taej Mundkur, Kiraz Erciyas Yavuz, Paul Leader, Connie Y.H. Leung, Bena Smith, Kyle A. Spragens, Kurt J. Vandegrift, Parviez R. Hosseini, Samia Saif, Samiul Mohsanin, Andrea Mikolon, Ausrafal Islam, Acty George, Balachandran Sivananinthaperumal, Peter Daszak, Scott H. Newman, 2014, Ecological Indicators on p. 266-273

Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2

Chen Chen, Veda Sheersh Boorla, Deepro Banerjee, Ratul Chowdhury, Victoria S. Cavener, Ruth H. Nissly, Abhinay Gontu, Nina R. Boyle, Kurt Vandegrift, Meera Surendran Nair, Suresh V. Kuchipudi, Costas D. Maranas, 2021, Proceedings of the National Academy of Sciences of the United States of America

MIReAD, a minimum information standard for reporting arthropod abundance data

Samuel S.C. Rund, Kyle Braak, Lauren Cator, Kyle Copas, Scott J. Emrich, Gloria I. Giraldo-Calderón, Michael A. Johansson, Naveed Heydari, Donald Hobern, Sarah A. Kelly, Daniel Lawson, Cynthia Lord, Robert M. MacCallum, Dominique G. Roche, Sadie J. Ryan, Dmitry Schigel, Kurt Vandegrift, Matthew Watts, Jennifer M. Zaspel, Samraat Pawar, 2019, Scientific data

Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

Suresh V. Kuchipudi, Meera Surendran-Nair, Rachel M. Ruden, Michele Yon, Ruth H. Nissly, Kurt J. Vandegrift, Rahul K. Nelli, Lingling Li, Bhushan M. Jayarao, Costas D. Maranas, Nicole Levine, Katriina Willgert, Andrew J.K. Conlan, Randall J. Olsen, James J. Davis, James M. Musser, Peter John Hudson, Vivek Kapur, 2022, Proceedings of the National Academy of Sciences of the United States of America

Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD): Emerging role of orthomyxoviruses in the pathogenesis of BRD

Ruth Nissly, Noriza Zaman, Ibrahim, Puteri Ainaa S., Puteri Ainaa S. Ibrahim, Ibrahim PAS, Kaitlin McDaniel, Levina Lim, Jennifer Kiser, Ian Bird, Shubhada Chothe, Gitanjali Bhushan, Kurt Vandegrift, Holly Neibergs, Kuchipudi, Suresh, V, Suresh V. Kuchipudi, 2020, Virology on p. 10-15

News Articles Featuring Kurt Vandegrift

COVID-19 May Be Widespread in Deer

An analysis by Penn State and Iowa researchers found that Covid-19 may be fairly widespread among white-tailed deer. Up to 80 percent of the deer sampled in Iowa from April 2020 through January 2021 were infected with COVID-19. And The U.S. Department of Agriculture has confirmed Covid infections in deer in 15 states total.

Omicron-Infected Whitetail Deer Detected in New York

The first cases of whitetail deer carrying the Omicron variant of the COVID-19 virus have been discovered in Staten Island, New York. Researchers there report that 19 of 131 deer sampled between December 12, 2021, and Janauary 31, 2022, tested positive for the virus’ antibodies, indicating prior exposure to the coronavirus. PCR (polymerase chain reaction) nasal swab testing of 68 deer revealed that seven were actively infected, with at least four of those confirmed to be Omicron.

Deer may be reservoir for SARS-CoV-2, study finds

The findings of a study by Penn State and Iowa researchers suggest that white-tailed deer may be a reservoir for the SARS-CoV-2 virus to continually circulate, and raises concerns of emergence of new strains that may prove a threat to wildlife and, possibly, to humans.

New tool predicts changes that may make COVID variants more infectious

The first key step in SARS-CoV-2 infection is when the virus’ spike protein binds to the ACE2 receptor on human cells. Researchers at Penn State have created a novel framework that can predict with reasonable accuracy the amino-acid changes in the virus’ spike protein that may improve its binding to human cells and confer increased infectivity to the virus.