Kenneth Keiler

Professor of Biochemistry and Molecular Biology

Kenneth Keiler

Research Summary

Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.

Huck Affiliations

Links

Publication Tags

Proteins Anti Bacterial Agents Bacteria Escherichia Coli Tmrna Students Ribosomes Teaching Shigella Flexneri Nanogel Polysaccharide Peptide Peptides Mycobacterium Tuberculosis Hyaluronic Acid Pharmaceutical Preparations Cyclic Peptides Rna Cells Membranes Polysaccharides Education Learning Survival Messenger Rna Staphylococcus Aureus

Most Recent Papers

A small-molecule inhibitor of trans-translation synergistically interacts with cathelicidin antimicrobial peptides to impair survival of staphylococcus aureus

Yueyang Huang, John N. Alumasa, Lauren T. Callaghan, R. Samuel Baugh, Christopher D. Rae, Kenneth C. Keiler, Shauna M. McGillivray, 2019, Antimicrobial agents and chemotherapy

Bioresponsive peptide-polysaccharide nanogels — A versatile delivery system to augment the utility of bioactive cargo

Andrew W. Simonson, Atip Lawanprasert, Tyler D.P. Goralski, Kenneth C. Keiler, Scott H. Medina, 2019, Nanomedicine: Nanotechnology, Biology, and Medicine on p. 391-400

Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA

Nicholas A. Dillon, Nicholas D. Peterson, Heather A. Feaga, Kenneth Charles Keiler, Anthony D. Baughn, 2017, Scientific reports

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells

John N. Alumasa, Paolo S. Manzanillo, Nicholas D. Peterson, Tricia Lundrigan, Anthony D. Baughn, Jeffery S. Cox, Kenneth C. Keiler, 2017, ACS Infectious Diseases on p. 634-644

Teaching broader impacts of science with undergraduate research

Kenneth C. Keiler, Kathy L. Jackson, Leslie Jaworski, David Lopatto, Sarah E. Ades, 2017, PLoS biology

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay

S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler, 2015, Antimicrobial agents and chemotherapy on p. 193-205

Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway

Shaima A. El-Mowafi, John N. Alumasa, Sarah E. Ades, Kenneth C. Keiler, 2014, Antimicrobial agents and chemotherapy on p. 5500-5509

tmRNA Is Essential in Shigella flexneri

Nitya S. Ramadoss, Xin Zhou, Kenneth C. Keiler, 2013, PloS one

Protein localization and dynamics within a bacterial organelle

H. Velocity Hughes, Edgar Huitema, Sean Pritchard, Kenneth C. Keiler, Yves V. Brun, Patrick H. Viollier, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 5599-5604

Subcellular localization of a bacterial regulatory RNA

Jay H. Russell, Kenneth C. Keiler, 2009, Proceedings of the National Academy of Sciences of the United States of America on p. 16405-16409

Most-Cited Papers

tmRNA Is Essential in Shigella flexneri

Nitya S. Ramadoss, Xin Zhou, Kenneth C. Keiler, 2013, PloS one

Protein localization and dynamics within a bacterial organelle

H. Velocity Hughes, Edgar Huitema, Sean Pritchard, Kenneth C. Keiler, Yves V. Brun, Patrick H. Viollier, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 5599-5604

Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA

Nicholas A. Dillon, Nicholas D. Peterson, Heather A. Feaga, Kenneth Charles Keiler, Anthony D. Baughn, 2017, Scientific reports

Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway

Shaima A. El-Mowafi, John N. Alumasa, Sarah E. Ades, Kenneth C. Keiler, 2014, Antimicrobial agents and chemotherapy on p. 5500-5509

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells

John N. Alumasa, Paolo S. Manzanillo, Nicholas D. Peterson, Tricia Lundrigan, Anthony D. Baughn, Jeffery S. Cox, Kenneth C. Keiler, 2017, ACS Infectious Diseases on p. 634-644

Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay

S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler, 2015, Antimicrobial agents and chemotherapy on p. 193-205

Teaching broader impacts of science with undergraduate research

Kenneth C. Keiler, Kathy L. Jackson, Leslie Jaworski, David Lopatto, Sarah E. Ades, 2017, PLoS biology

A small-molecule inhibitor of trans-translation synergistically interacts with cathelicidin antimicrobial peptides to impair survival of staphylococcus aureus

Yueyang Huang, John N. Alumasa, Lauren T. Callaghan, R. Samuel Baugh, Christopher D. Rae, Kenneth C. Keiler, Shauna M. McGillivray, 2019, Antimicrobial agents and chemotherapy

Bioresponsive peptide-polysaccharide nanogels — A versatile delivery system to augment the utility of bioactive cargo

Andrew W. Simonson, Atip Lawanprasert, Tyler D.P. Goralski, Kenneth C. Keiler, Scott H. Medina, 2019, Nanomedicine: Nanotechnology, Biology, and Medicine on p. 391-400

Tsp Protease

Kenneth Keiler, 2013, HANDBOOK OF PROTEOLYTIC ENZYMES, VOLS 1 AND 2, 3RD EDITION on p. 3605-3607