Kenneth Keiler
Professor of Biochemistry and Molecular Biology
-
401 Althouse
University Park, PA - kck11@psu.edu
- 814-863-0787
Research Summary
Small RNAs and protein localization in bacterial development and antimicrobial drug discovery.
Huck Affiliations
Links
Publication Tags
Proteins Anti Bacterial Agents Bacteria Escherichia Coli Tmrna Students Ribosomes Teaching Shigella Flexneri Nanogel Polysaccharide Peptide Peptides Mycobacterium Tuberculosis Hyaluronic Acid Pharmaceutical Preparations Cyclic Peptides Rna Cells Membranes Polysaccharides Education Learning Survival Messenger Rna Staphylococcus AureusMost Recent Papers
A small-molecule inhibitor of trans-translation synergistically interacts with cathelicidin antimicrobial peptides to impair survival of staphylococcus aureus
Yueyang Huang, John N. Alumasa, Lauren T. Callaghan, R. Samuel Baugh, Christopher D. Rae, Kenneth C. Keiler, Shauna M. McGillivray, 2019, Antimicrobial agents and chemotherapy
Bioresponsive peptide-polysaccharide nanogels — A versatile delivery system to augment the utility of bioactive cargo
Andrew W. Simonson, Atip Lawanprasert, Tyler D.P. Goralski, Kenneth C. Keiler, Scott H. Medina, 2019, Nanomedicine: Nanotechnology, Biology, and Medicine on p. 391-400
Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA
Nicholas A. Dillon, Nicholas D. Peterson, Heather A. Feaga, Kenneth Charles Keiler, Anthony D. Baughn, 2017, Scientific reports
Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells
John N. Alumasa, Paolo S. Manzanillo, Nicholas D. Peterson, Tricia Lundrigan, Anthony D. Baughn, Jeffery S. Cox, Kenneth C. Keiler, 2017, ACS Infectious Diseases on p. 634-644
Teaching broader impacts of science with undergraduate research
Kenneth C. Keiler, Kathy L. Jackson, Leslie Jaworski, David Lopatto, Sarah E. Ades, 2017, PLoS biology
Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay
S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler, 2015, Antimicrobial agents and chemotherapy on p. 193-205
Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway
Shaima A. El-Mowafi, John N. Alumasa, Sarah E. Ades, Kenneth C. Keiler, 2014, Antimicrobial agents and chemotherapy on p. 5500-5509
tmRNA Is Essential in Shigella flexneri
Nitya S. Ramadoss, Xin Zhou, Kenneth C. Keiler, 2013, PloS one
Protein localization and dynamics within a bacterial organelle
H. Velocity Hughes, Edgar Huitema, Sean Pritchard, Kenneth C. Keiler, Yves V. Brun, Patrick H. Viollier, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 5599-5604
Subcellular localization of a bacterial regulatory RNA
Jay H. Russell, Kenneth C. Keiler, 2009, Proceedings of the National Academy of Sciences of the United States of America on p. 16405-16409
Most-Cited Papers
tmRNA Is Essential in Shigella flexneri
Nitya S. Ramadoss, Xin Zhou, Kenneth C. Keiler, 2013, PloS one
Protein localization and dynamics within a bacterial organelle
H. Velocity Hughes, Edgar Huitema, Sean Pritchard, Kenneth C. Keiler, Yves V. Brun, Patrick H. Viollier, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 5599-5604
Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA
Nicholas A. Dillon, Nicholas D. Peterson, Heather A. Feaga, Kenneth Charles Keiler, Anthony D. Baughn, 2017, Scientific reports
Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway
Shaima A. El-Mowafi, John N. Alumasa, Sarah E. Ades, Kenneth C. Keiler, 2014, Antimicrobial agents and chemotherapy on p. 5500-5509
Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells
John N. Alumasa, Paolo S. Manzanillo, Nicholas D. Peterson, Tricia Lundrigan, Anthony D. Baughn, Jeffery S. Cox, Kenneth C. Keiler, 2017, ACS Infectious Diseases on p. 634-644
Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay
S. A. El-Mowafi, E. Sineva, J. N. Alumasa, H. Nicoloff, J. W. Tomsho, S. E. Ades, K. C. Keiler, 2015, Antimicrobial agents and chemotherapy on p. 193-205
Teaching broader impacts of science with undergraduate research
Kenneth C. Keiler, Kathy L. Jackson, Leslie Jaworski, David Lopatto, Sarah E. Ades, 2017, PLoS biology
A small-molecule inhibitor of trans-translation synergistically interacts with cathelicidin antimicrobial peptides to impair survival of staphylococcus aureus
Yueyang Huang, John N. Alumasa, Lauren T. Callaghan, R. Samuel Baugh, Christopher D. Rae, Kenneth C. Keiler, Shauna M. McGillivray, 2019, Antimicrobial agents and chemotherapy
Bioresponsive peptide-polysaccharide nanogels — A versatile delivery system to augment the utility of bioactive cargo
Andrew W. Simonson, Atip Lawanprasert, Tyler D.P. Goralski, Kenneth C. Keiler, Scott H. Medina, 2019, Nanomedicine: Nanotechnology, Biology, and Medicine on p. 391-400
Tsp Protease
Kenneth Keiler, 2013, HANDBOOK OF PROTEOLYTIC ENZYMES, VOLS 1 AND 2, 3RD EDITION on p. 3605-3607