Keefe Manning

Professor of Biomedical Engineering and Surgery

Keefe Manning

Research Summary

Understanding the native cardiovascular system fluid mechanics; understanding the diseased cardiovascular system fluid mechanics, and the impact that cardiovascular prosthetics generate during and post implantation.

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Computational Fluid Dynamics Blood Hydrodynamics Equipment And Supplies Benchmarking Biomedical Equipment Thrombosis Scaffolds Pumps Vena Cava Filters Anisotropy Nozzles United States Food And Drug Administration In Vitro Techniques Inferior Vena Cava Velocity Measurement Elastomeric Heart Valves Microfibers Catheters Tissue Pharynx Shear Stress Rheology Pressure

Most Recent Papers

In Vitro Clot Trapping Efficiency of the FDA Generic Inferior Vena Cava Filter in an Anatomical Model

J. M. Riley, N. S. Price, H. M. Saaid, B. C. Good, K. I. Aycock, B. A. Craven, K. B. Manning, 2021, Cardiovascular Engineering and Technology on p. 339-352

Refining a numerical model for device-induced thrombosis and investigating the effects of non-Newtonian blood models

Ling Yang, Nicolas Tobin, Keefe B. Manning, 2021, Journal of Biomechanics

In vitro real-time magnetic resonance imaging for quantification of thrombosis

Ling Yang, Thomas Neuberger, Keefe B. Manning, 2021, Magnetic Resonance Materials in Physics, Biology, and Medicine on p. 285-295

Special Issue on Professor John M. Tarbell’s Contribution to Cardiovascular Engineering

Hanjoong Jo, Keefe Manning, John M. Tarbell, 2021, Cardiovascular Engineering and Technology

John M. Tarbell

Keefe B. Manning, Steven Deutsch, Gerson Rosenberg, 2021, Cardiovascular Engineering and Technology on p. 9-14

Ultrasound-Responsive Nanopeptisomes Enable Synchronous Spatial Imaging and Inhibition of Clot Growth in Deep Vein Thrombosis

Janna N. Sloand, Eric Rokni, Connor T. Watson, Michael A. Miller, Keefe B. Manning, Julianna C. Simon, Scott H. Medina, 2021, Advanced healthcare materials

Transcatheter Heart Valve Downstream Fluid Dynamics in an Accelerated Evaluation Environment

Sailahari V. Ponnaluri, Steven Deutsch, Michael S. Sacks, Keefe B. Manning, 2021, Annals of Biomedical Engineering

Dynamics of Blood Flows in Aortic Stenosis

Choon-Sik Jhun, Raymond Newswanger, Joshua Cysyk, Sailahari Ponnaluri, Bryan Good, Keefe B. Manning, Gerson Rosenberg, 2021, ASAIO Journal on p. 666-674

Hydrodynamics in Acute Ischemic Stroke Catheters Under Static and Cyclic Aspiration Conditions

Bryan C. Good, Francesco Costanzo, Scott D. Simon, Keefe B. Manning, 2020, Cardiovascular Engineering and Technology on p. 689-698

Computational modeling of the Food and Drug Administration’s benchmark centrifugal blood pump

Bryan C. Good, Keefe B. Manning, 2020, Artificial Organs on p. E263-E276

Most-Cited Papers

Tri-layered elastomeric scaffolds for engineering heart valve leaflets

Nafiseh Masoumi, Nasim Annabi, Alexander Assmann, Benjamin L. Larson, Jesper Hjortnaes, Neslihan Alemdar, Mahshid Kharaziha, Keefe B. Manning, John E. Mayer, Ali Khademhosseini, 2014, Biomaterials on p. 7774-7785

Assessment of CFD Performance in Simulations of an Idealized Medical Device

Sandy F C Stewart, Eric G. Paterson, Greg W. Burgreen, Prasanna Hariharan, Matthew Giarra, Varun Reddy, Steven W. Day, Keefe B. Manning, Steven Deutsch, Michael R. Berman, Matthew R. Myers, Richard A. Malinauskas, 2012, Cardiovascular Engineering and Technology on p. 139-160

Multilaboratory particle image velocimetry analysis of the FDA benchmark nozzle model to support validation of computational fluid dynamics simulations

Prasanna Hariharan, Matthew Giarra, Varun Reddy, Steven W. Day, Keefe B. Manning, Steven Deutsch, Sandy F.C. Stewart, Matthew R. Myers, Michael R. Berman, Greg W. Burgreen, Eric G. Paterson, Richard A. Malinauskas, 2011, Journal of Biomechanical Engineering

Electrospun PGS

Nafiseh Masoumi, Benjamin L. Larson, Nasim Annabi, Mahshid Kharaziha, Behnam Zamanian, Kayle S. Shapero, Alexander T. Cubberley, Gulden Camci-Unal, Keefe B. Manning, John E. Mayer, Ali Khademhosseini, 2014, Advanced healthcare materials on p. 929-939

FDA Benchmark Medical Device Flow Models for CFD Validation

Richard A. Malinauskas, Prasanna Hariharan, Steven W. Day, Luke H. Herbertson, Martin Buesen, Ulrich Steinseifer, Kenneth I. Aycock, Bryan C. Good, Steven Deutsch, Keefe B. Manning, Brent A. Craven, 2017, ASAIO Journal on p. 150-160

Development of a computational model for macroscopic predictions of device-induced thrombosis

Joshua O. Taylor, Richard S. Meyer, Steven Deutsch, Keefe B. Manning, 2016, Biomechanics and Modeling in Mechanobiology on p. 1713-1731

Science for surgeons

Andreas R. De Biasi, Keefe B. Manning, Arash Salemi, 2015, Journal of Thoracic and Cardiovascular Surgery on p. 667-673

Results of FDA's First Interlaboratory Computational Study of a Nozzle with a Sudden Contraction and Conical Diffuser

Sandy F.C. Stewart, Prasanna Hariharan, Eric G. Paterson, Greg W. Burgreen, Varun Reddy, Steven W. Day, Matthew Giarra, Keefe B. Manning, Steven Deutsch, Michael R. Berman, Matthew R. Myers, Richard A. Malinauskas, 2013, Cardiovascular Engineering and Technology on p. 374-391

A Computational method for predicting inferior vena cava filter performance on a patient-specific basis

Kenneth I. Aycock, Robert Lee Campbell, Keefe B. Manning, Shankar P. Sastry, Suzanne M. Shontz, Frank Lynch, Brent A. Craven, 2014, Journal of Biomechanical Engineering

A resolved two-way coupled CFD/6-DOF approach for predicting embolus transport and the embolus-trapping efficiency of IVC filters

Kenneth I. Aycock, Robert L. Campbell, Keefe B. Manning, Brent A. Craven, 2017, Biomechanics and Modeling in Mechanobiology on p. 851-869