Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Joanna Floros

Huck Affiliations

Publication Tags

Surface Active Agents Proteins Pulmonary Surfactant Associated Protein A Alveolar Macrophages Ozone Varespladib Methyl Air Lung Klebsiella Pneumoniae Oxidation Reduction Gonadal Hormones Genes Oxidative Stress Proteome Nad Infection Pulmonary Surfactant Associated Protein D Bronchoalveolar Lavage Klebsiella Infections Innate Immunity Nutrients Actins Asthma Pulmonary Surfactant Associated Proteins G Protein Coupled Receptors

Most Recent Papers

Imaging nad(H) redox alterations in cryopreserved alveolar macrophages from ozone-exposed mice and the impact of nutrient starvation during long lag times

He N. Xu, Joanna Floros, Lin Z. Li, Shaili Amatya, 2021, Antioxidants

Can prophylactic high flow of humidified and warmed filtered air improve survival from bacterial pneumonia and sars-cov-2 in elderly individuals? The role of surfactant protein a

Ata Abbasi, David S. Phelps, Radhika Ravi, Joanna Floros, 2021, Antioxidants

SNP and Haplotype Interaction Models Reveal Association of Surfactant Protein Gene Polymorphisms With Hypersensitivity Pneumonitis of Mexican Population

Chintan K. Gandhi, Chixiang Chen, Shaili Amatya, Lili Yang, Chenqi Fu, Shouhao Zhou, Rongling Wu, Ivette Buendía-Roldan, Moisés Selman, Annie Pardo, Joanna Floros, 2021, Frontiers in Medicine

Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice

David S. Phelps, Vernon M. Chinchilli, Judith Weisz, Lili Yang, Debra Shearer, Xuesheng Zhang, Joanna Floros, 2020, JCI insight

Differential sex-dependent regulation of the alveolar macrophage mirnome of SP-A2 and co-ex (SP-A1/SP-A2) and sex differences attenuation after 18 h of ozone exposure

Nithyananda Thorenoor, David S. Phelps, Joanna Floros, 2020, Antioxidants on p. 1-23

Sex-dependent NAD(H) redox alteration in alveolar macrophages from mice expressing SP-A2 (but not from SP-A KO) in response to ozone exposure

He N. Xu, Zhenwu Lin, Chintan K. Gandhi, Shaili Amatya, Yunhua Wang, Lin Z. Li, Joanna Floros, 2020, Antioxidants on p. 1-19

Impact of ozone, sex, and gonadal hormones on bronchoalveolar lavage characteristics and survival in sp-a ko mice infected with klebsiella pneumoniae

Chintan K. Gandhi, Anatoly N. Mikerov, Faryal Durrani, Todd M. Umstead, Sanmei Hu, Guirong Wang, David S. Phelps, Joanna Floros, 2020, Microorganisms on p. 1-17

Impact of surfactant protein-a variants on survival in aged mice in response to klebsiella pneumoniae infection and ozone

Nithyananda Thorenoor, David S. Phelps, Padma Kala, Radhika Ravi, Andreas Floros Phelps, Todd M. Umstead, Xuesheng Zhang, Joanna Floros, 2020, Microorganisms on p. 1-23

Sex-Specific Regulation of Gene Expression Networks by Surfactant Protein A (SP-A) Variants in Alveolar Macrophages in Response to Klebsiella pneumoniae

Nithyananda Thorenoor, Yuka Imamura, Chintan K. Gandhi, Joanna Floros, 2020, Frontiers in Immunology

Association of SNP–SNP Interactions of Surfactant Protein Genes with Pediatric Acute Respiratory Failure

Chintan Gandhi, Chixiang Chen, Rongling Wu, L Yang, Nithyananda Thorenoor, Neal Thomas, Susan DiAngelo, D Spear, G Keim, N Yehya, Joanna Floros, 2020, Journal of Clinical Medicine on p. 1183

Most-Cited Papers

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury

Patricia Silveyra, Joanna Floros, 2012, Frontiers in Bioscience - Landmark on p. 407-429

Childhood asthma

Georgios T. Noutsios, Joanna Floros, 2014, Swiss Medical Weekly

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

Mi Young Yang, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Kunio Nagashima, Christina M. Burks, Lino Tessarollo, Pavlina T. Ivanova, H. Alex Brown, Todd M. Umstead, Joanna Floros, Zissis C. Chroneos, Brad St.Croix, 2013, Cell Reports on p. 1457-1464

Surfactant protein A is defective in abrogating inflammation in asthma

Ying Wang, Dennis R. Voelker, Njira L. Lugogo, Guirong Wang, Joanna Floros, Jennifer L. Ingram, Hong Wei Chu, Tony D. Church, Pitchaimani Kandasamy, Daniel Fertel, Jo Rae Wright, Monica Kraft, 2011, American Journal of Physiology on p. L598-L606

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection

Faryal Durrani, David S. Phelps, Judith Weisz, Patricia Silveyra, Sanmei Hu, Anatoly N. Mikerov, Joanna Floros, 2012, Experimental Lung Research on p. 165-172

Cyclic changes in the level of the innate immune molecule, surfactant protein-a, and cytokines in vaginal fluid

Colin Macneill, Glendell de Guzman, Grace E. Sousa, Todd M. Umstead, David Phelps, Joanna Floros, Kwangmi Ahn, Judith Weisz, 2012, American Journal of Reproductive Immunology on p. 244-250

Pilot study exploring lung allograft surfactant protein A (SP-A) expression in association with lung transplant outcome

F. D'Ovidio, H. Kaneda, C. Chaparro, M. Mura, D. Lederer, S. Di Angelo, H. Takahashi, C. Gutierrez, M. Hutcheon, L. G. Singer, T. K. Waddell, J. Floros, M. Liu, S. Keshavjee, 2013, American Journal of Transplantation on p. 2722-2729

Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial Films

Elena Lopez-Rodriguez, Alicia Pascual, Raquel Arroyo, Joanna Floros, Jesus Perez-Gil, 2016, Biophysical Journal on p. 524-536

In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement

David S. Phelps, Todd M. Umstead, Omar A. Quintero, Christopher M. Yengo, Joanna Floros, 2011, Proteome Science

Differential effects of human SP-A1 and SP-A2 on the BAL proteome and signaling pathways in response to Klebsiella pneumoniae and ozone exposure

Guirong Wang, Todd M. Umstead, Sanmei Hu, Anatoly N. Mikerov, David S. Phelps, Joanna Floros, 2019, Frontiers in Immunology