Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Joanna Floros

Publication Tags

Surface Active Agents Proteins Pulmonary Surfactant Associated Protein A Lung Varespladib Methyl Oxidative Stress Genes Klebsiella Pneumoniae Alveolar Macrophages Sex Characteristics Pulmonary Surfactant Associated Protein D Air Klebsiella Infections Proteome Pulmonary Surfactant Associated Proteins Gonadal Hormones Ozone Transgenic Mice Messenger Rna Micrornas Infection Cytokines Transplants Tubular Myelin G Protein Coupled Receptors

Most Recent Papers

Structural and Functional Determinants of Rodent and Human Surfactant Protein A

Armen Nalian, Todd M. Umstead, Ching Hui Yang, Patricia Silveyra, Neal J. Thomas, Joanna Floros, Francis X. McCormack, Zissis C. Chroneos, 2019, Frontiers in immunology

Surfactant protein A and D polymorphisms and methylprednisolone pharmacogenetics in donor lungs

Beatrice Aramini, Patrick Geraghty, David J. Lederer, Joseph Costa, Susan L. DiAngelo, Joanna Floros, Frank D'Ovidio, 2019, Journal of Thoracic and Cardiovascular Surgery on p. 2109-2117

Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa

Colin Macneill, Glendell S. De Guzman, Kate Lupo, Todd Umstead, David Phelps, Joanna Floros, 2019, Journal of Lower Genital Tract Disease on p. 71-74

Major effect of oxidative stress on the Male, but not female, SP-A1 type II cell miRNome

George T. Noutsios, Nithyananda Thorenoor, Xuesheng Zhang, David S. Phelps, Todd M. Umstead, Faryal Durrani, Joanna Floros, 2019, Frontiers in immunology

Differential impact of co-expressed SP-A1/SP-A2 protein on AM miRNome; Sex differences

Nithyananda Thorenoor, Yuka Imamura Kawasawa, Chintan K. Gandhi, Xuesheng Zhang, Joanna Floros, 2019, Frontiers in immunology

Differential effects of human SP-A1 and SP-A2 on the BAL proteome and signaling pathways in response to Klebsiella pneumoniae and ozone exposure

Guirong Wang, Todd M. Umstead, Sanmei Hu, Anatoly N. Mikerov, David S. Phelps, Joanna Floros, 2019, Frontiers in immunology

Survival of surfactant protein-A1 and SP-A2 transgenic mice after Klebsiella pneumoniae infection, exhibits sex-, gene-, and variant specific differences; Treatment with surfactant protein improves survival

Nithyananda Thorenoor, Todd M. Umstead, Xuesheng Zhang, David S. Phelps, Joanna Floros, 2018, Frontiers in immunology

Genetic association of pulmonary surfactant protein genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD with cystic fibrosis

Zhenwu Lin, Nithyananda Thorenoor, Rongling Wut, Susan L. Di Angelo, Meixia Ye, Neal J. Thomas, Xiaojie Liao, Tony R. Lin, Stuart Warren, Joanna Floros, 2018, Frontiers in immunology

Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences

Nithyananda Thorenoor, Xuesheng Zhang, Todd M. Umstead, E. Scott Halstead, David S. Phelps, Joanna Floros, 2018, Respiratory research

SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress

George T. Noutsios, Nithyananda Thorenoor, Xuesheng Zhang, David S. Phelps, Todd M. Umstead, Faryal Durrani, Joanna Floros, 2017, Biology of Sex Differences

Most-Cited Papers

Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2

Guirong Wang, Xiaoxuan Guo, Susan DiAngelo, Neal J. Thomas, Joanna Floros, 2010, Journal of Biological Chemistry on p. 11998-12010

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury

Patricia Silveyra, Joanna Floros, 2012, Frontiers in Bioscience on p. 407-429

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

Mi Young Yang, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Kunio Nagashima, Christina M. Burks, Lino Tessarollo, Pavlina T. Ivanova, H. Alex Brown, Todd M. Umstead, Joanna Floros, Zissis C. Chroneos, Brad St.Croix, 2013, Cell Reports on p. 1457-1464

Surfactant protein A is defective in abrogating inflammation in asthma

Ying Wang, Dennis R. Voelker, Njira L. Lugogo, Guirong Wang, Joanna Floros, Jennifer L. Ingram, Hong Wei Chu, Tony D. Church, Pitchaimani Kandasamy, Daniel Fertel, Jo Rae Wright, Monica Kraft, 2011, American Journal of Physiology - Lung Cellular and Molecular Physiology on p. L598-L606

Cyclic changes in the level of the innate immune molecule, surfactant protein-a, and cytokines in vaginal fluid

Colin Macneill, Glendell de Guzman, Grace E. Sousa, Todd M. Umstead, David Phelps, Joanna Floros, Kwangmi Ahn, Judith Weisz, 2012, American Journal of Reproductive Immunology on p. 244-250

Pilot study exploring lung allograft surfactant protein A (SP-A) expression in association with lung transplant outcome

F. D'Ovidio, H. Kaneda, C. Chaparro, M. Mura, D. Lederer, S. Di Angelo, H. Takahashi, C. Gutierrez, M. Hutcheon, L. G. Singer, T. K. Waddell, J. Floros, M. Liu, S. Keshavjee, 2013, American Journal of Transplantation on p. 2722-2729

In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement

David Phelps, Todd M. Umstead, Omar A. Quintero, Christopher Yengo, Joanna Floros, 2011, Proteome Science

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection

Faryal Durrani, David Phelps, Judith Weisz, Patricia Silveyra, Sanmei Hu, Anatoly N. Mikerov, Joanna Floros, 2012, Experimental Lung Research on p. 165-172

Donor surfactant protein D (SP-D) polymorphisms are associated with lung transplant outcome

B. Aramini, C. Kim, S. Diangelo, E. Petersen, D. J. Lederer, L. Shah, H. Robbins, Joanna Floros, S. M. Arcasoy, J. R. Sonett, F. D'Ovidio, 2013, American Journal of Transplantation on p. 2130-2136

Histopathologic evaluation of lung and extrapulmonary tissues show sex differences in klebsiella pneumoniae - infected mice under different exposure conditions

Anatoly N. Mikerov, Timothy K. Cooper, Guirong Wang, Sanmei Hu, Todd M. Umstead, David S. Phelps, Joanna Floros, 2011, International Journal of Physiology, Pathophysiology and Pharmacology on p. 176-190