Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Joanna Floros

Huck Affiliations

Publication Tags

Surface Active Agents Proteins Pulmonary Surfactant Associated Protein A Alveolar Macrophages Varespladib Methyl Lung Ozone Klebsiella Pneumoniae Oxidation Reduction Air Gonadal Hormones Oxidative Stress Genes Infection Klebsiella Infections Sex Characteristics Inflammation Pulmonary Surfactant Associated Proteins Pulmonary Surfactant Associated Protein D G Protein Coupled Receptors Proteome Transplants Actins Nad Knockout Mice

Most Recent Papers

Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice

David S. Phelps, Vernon M. Chinchilli, Judith Weisz, Lili Yang, Debra Shearer, Xuesheng Zhang, Joanna Floros, 2020, JCI insight

Differential sex-dependent regulation of the alveolar macrophage mirnome of SP-A2 and co-ex (SP-A1/SP-A2) and sex differences attenuation after 18 h of ozone exposure

Nithyananda Thorenoor, David S. Phelps, Joanna Floros, 2020, Antioxidants on p. 1-23

Sex-dependent NAD(H) redox alteration in alveolar macrophages from mice expressing SP-A2 (but not from SP-A KO) in response to ozone exposure

He N. Xu, Zhenwu Lin, Chintan K. Gandhi, Shaili Amatya, Yunhua Wang, Lin Z. Li, Joanna Floros, 2020, Antioxidants on p. 1-19

Impact of ozone, sex, and gonadal hormones on bronchoalveolar lavage characteristics and survival in sp-a ko mice infected with klebsiella pneumoniae

Chintan K. Gandhi, Anatoly N. Mikerov, Faryal Durrani, Todd M. Umstead, Sanmei Hu, Guirong Wang, David S. Phelps, Joanna Floros, 2020, Microorganisms on p. 1-17

Impact of surfactant protein-a variants on survival in aged mice in response to klebsiella pneumoniae infection and ozone

Nithyananda Thorenoor, David S. Phelps, Padma Kala, Radhika Ravi, Andreas Floros Phelps, Todd M. Umstead, Xuesheng Zhang, Joanna Floros, 2020, Microorganisms on p. 1-23

Sex-Specific Regulation of Gene Expression Networks by Surfactant Protein A (SP-A) Variants in Alveolar Macrophages in Response to Klebsiella pneumoniae

Nithyananda Thorenoor, Yuka Imamura, Chintan K. Gandhi, Joanna Floros, 2020, Frontiers in Immunology

Association of SNP–SNP Interactions of Surfactant Protein Genes with Pediatric Acute Respiratory Failure

Chintan Gandhi, Chixiang Chen, Rongling Wu, L Yang, Nithyananda Thorenoor, Neal Thomas, Susan DiAngelo, D Spear, G Keim, N Yehya, Joanna Floros, 2020, Journal of Clinical Medicine on p. 1183

Donor surfactant protein A2 polymorphism and lung transplant survival

Frank D'Ovidio, Joanna Floros, Beatrice Aramini, David Lederer, Susan L. DiAngelo, Selim Arcasoy, Joshua R. Sonett, Hillary Robbins, Lory Shah, Joseph Costa, Andreacarola Urso, 2020, European Respiratory Journal

Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1

David S. Phelps, Vernon M. Chinchilli, Judith Weisz, Debra Shearer, Xuesheng Zhang, Joanna Floros, 2020, Biomarker Research

The importance of redox status in the frame of lifestyle approaches and the genetics of the lung innate immune molecules, SP-A1 and SP-A2, on differential outcomes of covid-19 infection

Fotios Tekos, Zoi Skaperda, Nikolaos Goutzourelas, David S. Phelps, Joanna Floros, Demetrios Kouretas, 2020, Antioxidants on p. 1-22

Most-Cited Papers

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury

Patricia Silveyra, Joanna Floros, 2012, Frontiers in Bioscience - Landmark on p. 407-429

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

Mi Young Yang, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Kunio Nagashima, Christina M. Burks, Lino Tessarollo, Pavlina T. Ivanova, H. Alex Brown, Todd M. Umstead, Joanna Floros, Zissis C. Chroneos, Brad St.Croix, 2013, Cell Reports on p. 1457-1464

Surfactant protein A is defective in abrogating inflammation in asthma

Ying Wang, Dennis R. Voelker, Njira L. Lugogo, Guirong Wang, Joanna Floros, Jennifer L. Ingram, Hong Wei Chu, Tony D. Church, Pitchaimani Kandasamy, Daniel Fertel, Jo Rae Wright, Monica Kraft, 2011, American Journal of Physiology on p. L598-L606

Cyclic changes in the level of the innate immune molecule, surfactant protein-a, and cytokines in vaginal fluid

Colin Macneill, Glendell de Guzman, Grace E. Sousa, Todd M. Umstead, David Phelps, Joanna Floros, Kwangmi Ahn, Judith Weisz, 2012, American Journal of Reproductive Immunology on p. 244-250

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection

Faryal Durrani, David S. Phelps, Judith Weisz, Patricia Silveyra, Sanmei Hu, Anatoly N. Mikerov, Joanna Floros, 2012, Experimental Lung Research on p. 165-172

Pilot study exploring lung allograft surfactant protein A (SP-A) expression in association with lung transplant outcome

F. D'Ovidio, H. Kaneda, C. Chaparro, M. Mura, D. Lederer, S. Di Angelo, H. Takahashi, C. Gutierrez, M. Hutcheon, L. G. Singer, T. K. Waddell, J. Floros, M. Liu, S. Keshavjee, 2013, American Journal of Transplantation on p. 2722-2729

In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement

David S. Phelps, Todd M. Umstead, Omar A. Quintero, Christopher M. Yengo, Joanna Floros, 2011, Proteome Science

Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial Films

Elena Lopez-Rodriguez, Alicia Pascual, Raquel Arroyo, Joanna Floros, Jesus Perez-Gil, 2016, Biophysical Journal on p. 524-536

Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice

Anatoly N. Mikerov, Sanmei Hu, Faryal Durrani, Xiaozhuang Gan, Guirong Wang, Todd M. Umstead, David Phelps, Joanna Floros, 2012, Microbial Pathogenesis on p. 239-249

Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences

Nithyananda Thorenoor, Xuesheng Zhang, Todd M. Umstead, E. Scott Halstead, David S. Phelps, Joanna Floros, 2018, Respiratory Research