Joanna Floros

Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

Joanna Floros

Huck Affiliations

Publication Tags

Surface Active Agents Proteins Pulmonary Surfactant Associated Protein A Alveolar Macrophages Varespladib Methyl Lung Knockout Mice Proteome Klebsiella Pneumoniae Surfactant Genes Single Nucleotide Polymorphism Infections Oxidative Stress Sex Characteristics Klebsiella Infections Protein Air Pulmonary Surfactant Associated Protein D Child Innate Immunity G Protein Coupled Receptors Gonadal Hormones Ozone Infection

Most Recent Publications

The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue

David S. Phelps, Vernon M. Chinchilli, Lili Yang, Debra Shearer, Judith Weisz, Xuesheng Zhang, Joanna Floros, 2022, Scientific Reports

Hydrophilic But Not Hydrophobic Surfactant Protein Genetic Variants Are Associated With Severe Acute Respiratory Syncytial Virus Infection in Children

Lynnlee C. Depicolzuane, Catherine M. Roberts, Neal J. Thomas, Keenan Anderson-Fears, Dajiang Liu, João Paulo Pereira Barbosa, Felipe Rodrigues Souza, André Silva Pimentel, Joanna Floros, Chintan K. Gandhi, 2022, Frontiers in Immunology

The Lung Alveolar Cell (LAC) miRNome and Gene Expression Profile of the SP-A-KO Mice After Infection With and Without Rescue With Human Surfactant Protein-A2 (1A<sup>0</sup>)

Nithyananda Thorenoor, Joanna Floros, 2022, Frontiers in Immunology

Single Nucleotide Polymorphisms (SNP) and SNP-SNP Interactions of the Surfactant Protein Genes Are Associated With Idiopathic Pulmonary Fibrosis in a Mexican Study Group; Comparison With Hypersensitivity Pneumonitis

Ata Abbasi, Chixiang Chen, Chintan K. Gandhi, Rongling Wu, Annie Pardo, Moises Selman, Joanna Floros, 2022, Frontiers in Immunology

Comparison of the Toponomes of Alveolar Macrophages From Wild Type and Surfactant Protein A Knockout Mice and Their Response to Infection

David S. Phelps, Vernon M. Chinchilli, Xuesheng Zhang, Debra Shearer, Judith Weisz, Joanna Floros, 2022, Frontiers in Immunology

A Pilot Proteomic Study of Vestibular Fluid From Patients With Vulvodynia

Colin MacNeill, Todd Umstead, Debra Shearer, Judith Weisz, David S. Phelps, Joanna Floros, 2022, Journal of Lower Genital Tract Disease on p. 169-175

SNP–SNP Interactions of Surfactant Protein Genes in Persistent Respiratory Morbidity Susceptibility in Previously Healthy Children

Chintan K. Gandhi, Neal J. Thomas, Ye Meixia, Debbie Spear, Chenqi Fu, Shouhao Zhou, Rongling Wu, Garrett Keim, Nadir Yehya, Joanna Floros, 2022, Frontiers in Genetics

Surfactant Protein-A Function: Knowledge Gained From SP-A Knockout Mice

Lynnlee Depicolzuane, David S. Phelps, Joanna Floros, 2022, Frontiers in Pediatrics

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants

Joanna Floros, Nikolaos Tsotakos, 2021, Frontiers in Immunology

Single Nucleotide Polymorphisms Interactions of the Surfactant Protein Genes Associated With Respiratory Distress Syndrome Susceptibility in Preterm Infants

Shaili Amatya, Meixia Ye, Lili Yang, Chintan K. Gandhi, Rongling Wu, Beth Nagourney, Joanna Floros, 2021, Frontiers in Pediatrics

Most-Cited Papers

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury

Patricia Silveyra, Joanna Floros, 2012, Frontiers in Bioscience - Landmark on p. 407-429

Childhood asthma: Causes, risks, and protective factors; a role of innate immunity

Georgios T. Noutsios, Joanna Floros, 2014, Swiss Medical Weekly

Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

Mi Young Yang, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Kunio Nagashima, Christina M. Burks, Lino Tessarollo, Pavlina T. Ivanova, H. Alex Brown, Todd M. Umstead, Joanna Floros, Zissis C. Chroneos, Brad St.Croix, 2013, Cell Reports on p. 1457-1464

Differential effects of human SP-A1 and SP-A2 on the BAL proteome and signaling pathways in response to Klebsiella pneumoniae and ozone exposure

Guirong Wang, Todd M. Umstead, Sanmei Hu, Anatoly N. Mikerov, David S. Phelps, Joanna Floros, 2019, Frontiers in Immunology

Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial Films

Elena Lopez-Rodriguez, Alicia Pascual, Raquel Arroyo, Joanna Floros, Jesus Perez-Gil, 2016, Biophysical Journal on p. 524-536

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection

Faryal Durrani, David S. Phelps, Judith Weisz, Patricia Silveyra, Sanmei Hu, Anatoly N. Mikerov, Joanna Floros, 2012, Experimental Lung Research on p. 165-172

Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences

Nithyananda Thorenoor, Xuesheng Zhang, Todd M. Umstead, E. Scott Halstead, David S. Phelps, Joanna Floros, 2018, Respiratory Research

Survival of surfactant protein-A1 and SP-A2 transgenic mice after Klebsiella pneumoniae infection, exhibits sex-, gene-, and variant specific differences; Treatment with surfactant protein improves survival

Nithyananda Thorenoor, Todd M. Umstead, Xuesheng Zhang, David S. Phelps, Joanna Floros, 2018, Frontiers in Immunology

Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A

David S. Phelps, Todd M. Umstead, Joanna Floros, 2012, Proteome Science

Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome

David S. Phelps, Todd M. Umstead, Joanna Floros, 2014, Journal of Proteomics on p. 427-444