Joanna Floros
Evan Pugh Professor of Cellular and Molecular Physiology,OB/GYN

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Hershey Med Ctr
University Park, - jxf19@psu.edu
Huck Affiliations
Publication Tags
Surface Active Agents Proteins Pulmonary Surfactant Associated Protein A Alveolar Macrophages Varespladib Methyl Lung Air Genes Klebsiella Pneumoniae Surfactant Oxidative Stress Ozone Klebsiella Infections Protein Proteome Knockout Mice Pulmonary Surfactant Associated Protein D Sex Characteristics Single Nucleotide Polymorphism Infections Innate Immunity Pulmonary Surfactant Associated Proteins Nutrients G Protein Coupled Receptors SurvivalMost Recent Papers
The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue
David S. Phelps, Vernon M. Chinchilli, Lili Yang, Debra Shearer, Judith Weisz, Xuesheng Zhang, Joanna Floros, 2022, Scientific Reports
Comparison of the Toponomes of Alveolar Macrophages From Wild Type and Surfactant Protein A Knockout Mice and Their Response to Infection
David S. Phelps, Vernon M. Chinchilli, Xuesheng Zhang, Debra Shearer, Judith Weisz, Joanna Floros, 2022, Frontiers in Immunology
A Pilot Proteomic Study of Vestibular Fluid From Patients With Vulvodynia
Colin MacNeill, Todd Umstead, Debra Shearer, Judith Weisz, David S. Phelps, Joanna Floros, 2022, Journal of Lower Genital Tract Disease on p. 169-175
SNP–SNP Interactions of Surfactant Protein Genes in Persistent Respiratory Morbidity Susceptibility in Previously Healthy Children
Chintan K. Gandhi, Neal J. Thomas, Ye Meixia, Debbie Spear, Chenqi Fu, Shouhao Zhou, Rongling Wu, Garrett Keim, Nadir Yehya, Joanna Floros, 2022, Frontiers in Genetics
Surfactant Protein-A Function
Lynnlee Depicolzuane, David S. Phelps, Joanna Floros, 2022, Frontiers in Pediatrics
Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants
Joanna Floros, Nikolaos Tsotakos, 2021, Frontiers in Immunology
Single Nucleotide Polymorphisms Interactions of the Surfactant Protein Genes Associated With Respiratory Distress Syndrome Susceptibility in Preterm Infants
Shaili Amatya, Meixia Ye, Lili Yang, Chintan K. Gandhi, Rongling Wu, Beth Nagourney, Joanna Floros, 2021, Frontiers in Pediatrics
Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions
Joanna Floros, Nithyananda Thorenoor, Nikolaos Tsotakos, David S. Phelps, 2021, Frontiers in Immunology
Can prophylactic high flow of humidified and warmed filtered air improve survival from bacterial pneumonia and sars-cov-2 in elderly individuals? The role of surfactant protein a
Ata Abbasi, David S. Phelps, Radhika Ravi, Joanna Floros, 2021, Antioxidants
Imaging nad(H) redox alterations in cryopreserved alveolar macrophages from ozone-exposed mice and the impact of nutrient starvation during long lag times
He N. Xu, Joanna Floros, Lin Z. Li, Shaili Amatya, 2021, Antioxidants
Most-Cited Papers
Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury
Patricia Silveyra, Joanna Floros, 2012, Frontiers in Bioscience - Landmark on p. 407-429
Childhood asthma
Georgios T. Noutsios, Joanna Floros, 2014, Swiss Medical Weekly
Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116
Mi Young Yang, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Kunio Nagashima, Christina M. Burks, Lino Tessarollo, Pavlina T. Ivanova, H. Alex Brown, Todd M. Umstead, Joanna Floros, Zissis C. Chroneos, Brad St.Croix, 2013, Cell Reports on p. 1457-1464
Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial Films
Elena Lopez-Rodriguez, Alicia Pascual, Raquel Arroyo, Joanna Floros, Jesus Perez-Gil, 2016, Biophysical Journal on p. 524-536
Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection
Faryal Durrani, David S. Phelps, Judith Weisz, Patricia Silveyra, Sanmei Hu, Anatoly N. Mikerov, Joanna Floros, 2012, Experimental Lung Research on p. 165-172
Differential effects of human SP-A1 and SP-A2 on the BAL proteome and signaling pathways in response to Klebsiella pneumoniae and ozone exposure
Guirong Wang, Todd M. Umstead, Sanmei Hu, Anatoly N. Mikerov, David S. Phelps, Joanna Floros, 2019, Frontiers in Immunology
Survival of surfactant protein-A1 and SP-A2 transgenic mice after Klebsiella pneumoniae infection, exhibits sex-, gene-, and variant specific differences; Treatment with surfactant protein improves survival
Nithyananda Thorenoor, Todd M. Umstead, Xuesheng Zhang, David S. Phelps, Joanna Floros, 2018, Frontiers in Immunology
Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences
Nithyananda Thorenoor, Xuesheng Zhang, Todd M. Umstead, E. Scott Halstead, David S. Phelps, Joanna Floros, 2018, Respiratory Research
Pilot study exploring lung allograft surfactant protein A (SP-A) expression in association with lung transplant outcome
F. D'Ovidio, H. Kaneda, C. Chaparro, M. Mura, D. Lederer, S. Di Angelo, H. Takahashi, C. Gutierrez, M. Hutcheon, L. G. Singer, T. K. Waddell, J. Floros, M. Liu, S. Keshavjee, 2013, American Journal of Transplantation on p. 2722-2729
Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome
David S. Phelps, Todd M. Umstead, Joanna Floros, 2014, Journal of Proteomics on p. 427-444