Jian Yang

Huck Chair in Regenerative Engineering; Professor of Biomedical Engineering

Jian Yang

Research Summary

Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.

Huck Affiliations

Links

Publication Tags

Tissue Antioxidants Elastomers Citric Acid Bioadhesive Application Intercellular Signaling Peptides And Proteins Tannins Antioxidant Agent Oxidative Stress Tissue Engineering Wound Healing Skin Wounds And Injuries Nanofibers Polyesters Transistors Silicon Polyurethanes Collagen Adhesives Nanoparticles Tissue Adhesives Mechanical Properties Biodegradable Polymers

Most Recent Publications

Anti-oxidant anti-inflammatory and antibacterial tannin-crosslinked citrate-based mussel-inspired bioadhesives facilitate scarless wound healing

Keke Wu, Meimei Fu, Yitao Zhao, Ethan Gerhard, Yue Li, Jian Yang, Jinshan Guo, 2023, Bioactive Materials on p. 93-110

Smart bioadhesives for wound healing and closure

Jia Zhu, Honglei Zhou, Ethan Michael Gerhard, Senhao Zhang, Flor Itzel Parra Rodríguez, Taisong Pan, Hongbo Yang, Yuan Lin, Jian Yang, Huanyu Cheng, 2023, Bioactive Materials on p. 360-375

Development of Biodegradable Osteopromotive Citrate-Based Bone Putty

Xinyu Tan, Ethan Gerhard, Yuqi Wang, Richard T. Tran, Hui Xu, Su Yan, Elias B. Rizk, April D. Armstrong, Yuxiao Zhou, Jing Du, Xiaochun Bai, Jian Yang, 2022, Small

Citrate-based fluorometric sensor for multi-halide sensing

Dingbowen Wang, Tunan Xia, Yuqi Wang, Yizhu Chen, Chenji Zhang, William Murray, Adam Thomas Schultz, Zhiwen Liu, Jian Yang, 2022, Smart Materials in Medicine on p. 374-381

Biodegradable and Inherently Fluorescent pH-Responsive Nanoparticles for Cancer Drug Delivery

Kalindu Perera, Dat X. Nguyen, Dingbowen Wang, Aneetta E. Kuriakose, Jian Yang, Kytai T. Nguyen, Jyothi U. Menon, 2022, Pharmaceutical Research

Aggregation-induced emission luminogens for highly effective microwave dynamic therapy

Nil Kanatha Pandey, Wei Xiong, Lingyun Wang, Wei Chen, Brian Bui, Jian Yang, Eric Amador, Mingli Chen, Christina Xing, Aseem Atul Athavale, Yaowu Hao, Wirya Feizi, Lloyd Lumata, 2022, Bioactive Materials on p. 112-125

Synthesis and characterization of a novel pH-responsive drug-releasing nanocomposite hydrogel for skin cancer therapy and wound healing

Andrea Gonsalves, Pranjali Tambe, Duong Le, Dheeraj Thakore, Aniket S. Wadajkar, Jian Yang, Kytai T. Nguyen, Jyothi U. Menon, 2021, Journal of Materials Chemistry B on p. 9533-9546

Phototherapy and optical waveguides for the treatment of infection

Dingbowen Wang, Michelle Laurel Kuzma, Xinyu Tan, Tong Chuan He, Cheng Dong, Zhiwen Liu, Jian Yang, 2021, Advanced Drug Delivery Reviews

Self-assembling peptide hydrogels facilitate vascularization in two-component scaffolds

Zain Siddiqui, Biplab Sarkar, Ka Kyung Kim, Arjun Kumar, Reshma Paul, Aryan Mahajan, Jonathan M. Grasman, Jian Yang, Vivek A. Kumar, 2021, Chemical Engineering Journal

Syntheses and characterization of anti-thrombotic and anti-oxidative Gastrodin-modified polyurethane for vascular tissue engineering

Meng Zheng, Jiazhi Guo, Qing Li, Jian Yang, Yi Han, Hongcai Yang, Mali Yu, Lianmei Zhong, Di Lu, Limei Li, Lin Sun, 2021, Bioactive Materials on p. 404-419

Most-Cited Papers

Three-dimensional manipulation of single cells using surface acoustic waves

Feng Guo, Zhangming Mao, Yuchao Chen, Zhiwei Xie, James P. Lata, Peng Li, Liqiang Ren, Jiayang Liu, Jian Yang, Ming Dao, Subra Suresh, Tony Jun Huang, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1522-1527

Dual growth factor releasing multi-functional nanofibers for wound healing

Zhiwei Xie, Christian B. Paras, Hong Weng, Primana Punnakitikashem, Lee Chun Su, Khanh Vu, Liping Tang, Jian Yang, Kytai T. Nguyen, 2013, Acta Biomaterialia on p. 9351-9359

Injectable citrate-based mussel-inspired tissue bioadhesives with high wet strength for sutureless wound closure

Mohammadreza Mehdizadeh, Hong Weng, Dipendra Gyawali, Liping Tang, Jian Yang, 2012, Biomaterials on p. 7972-7983

Design Strategies and Applications of Tissue Bioadhesives

Mohammadreza Mehdizadeh, Jian Yang, 2013, Macromolecular Bioscience on p. 271-288

Biodegradable elastomers and silicon nanomembranes/nanoribbons for stretchable, transient electronics, and biosensors

Suk Won Hwang, Chi Hwan Lee, Huanyu Cheng, Jae Woong Jeong, Seung Kyun Kang, Jae Hwan Kim, Jiho Shin, Jian Yang, Zhuangjian Liu, Guillermo A. Ameer, Yonggang Huang, John A. Rogers, 2015, Nano Letters on p. 2801-2808

Development of tannin-inspired antimicrobial bioadhesives

Jinshan Guo, Wei Sun, Jimin Peter Kim, Xili Lu, Qiyao Li, Min Lin, Oliver Mrowczynski, Elias B. Rizk, Juange Cheng, Guoying Qian, Jian Yang, 2018, Acta Biomaterialia on p. 35-44

Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems

Yixue Su, Zhiwei Xie, Gloria B. Kim, Cheng Dong, Jian Yang, 2015, ACS Biomaterials Science and Engineering on p. 201-217

3D-Printing Strong High-Resolution Antioxidant Bioresorbable Vascular Stents

Robert van Lith, Evan Baker, Henry Ware, Jian Yang, Adam Cyrus Farsheed, Cheng Sun, Guillermo Ameer, 2016, Advanced Materials Technologies

A thermoresponsive biodegradable polymer with intrinsic antioxidant properties

Jian Yang, Robert Van Lith, Kevin Baler, Ryan A. Hoshi, Guillermo A. Ameer, 2014, Biomacromolecules on p. 3942-3952

Engineering biodegradable polyester elastomers with antioxidant properties to attenuate oxidative stress in tissues

Robert van Lith, Elaine K. Gregory, Jian Yang, Melina R. Kibbe, Guillermo A. Ameer, 2014, Biomaterials on p. 8113-8122

News Articles Featuring Jian Yang

Sep 16, 2022

Millennium Café series to feature special editions in October, November

The Millennium Café, held every Tuesday by the Materials Research Institute (MRI) featuring two talks by Penn State researchers that serve as an exchange of ideas and solutions, will hold three special sessions in October and November.

Full Article

Aug 16, 2022

Researchers to develop scaffolding for nerve regeneration with $2.14M NIH grant

Peripheral nerves are responsible for moving muscles, sensing temperatures and even inhaling and exhaling; yet they comprise fragile fibers vulnerable to disease and injury.

Full Article

May 19, 2022

College of Engineering awards six Multidisciplinary Research Seed Grants

The Penn State College of Engineering recently awarded six Multidisciplinary Research Seed Grants to faculty members, including one in partnership with the College of Health and Human Development and another with the Huck Institutes of the Life Sciences.

Full Article

Jun 11, 2021

New tissue-closure model may aid in promotion of faster wound healing

The observation of a previously undetected biological mechanism for closing gaps in living tissue improves basic understanding of the wound-healing process and may one day inform strategies to speed healing after surgery.

Full Article

Oct 21, 2020

Novel bioresorbable, tissue-healing surgical device approved by FDA

A new surgical tendon fixation system that not only re-attaches damaged tissues but also facilitates healing as it is absorbed by the body has been granted 510(k) clearance by the U.S. Food and Drug Administration, indicating that the device is “as safe and effective” as other legally marketed devices and is ready to go to market.

Full Article

Feb 03, 2020

Academia-enterprise partnership aims to help people with diabetes

Innovative wound dressing would help reduce life-threatening infections, amputations for diabetic patients.

Full Article