Jian Yang

Huck Chair in Regenerative Engineering; Professor of Bioengineering

Jian Yang

Research Summary

Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.

Huck Affiliations

Links

Publication Tags

Citric Acid Polymers Biodegradable Polymers Nanoparticles Elastomers Degradation Tissue Biocompatible Materials Intercellular Signaling Peptides And Proteins Antioxidants Imaging Techniques Mechanistic Target Of Rapamycin Complex 1 Oxidative Stress Tissue Engineering Mechanical Properties Nanofibers Polyesters Drug Delivery Proteins Polyethylene Glycols Biomaterials Stem Cells Monitoring Maleic Acid Crosslinking

Most Recent Papers

Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration

Yun He, Qiyao Li, Chuying Ma, Denghui Xie, Limei Li, Yitao Zhao, Dingying Shan, Sarah K. Chomos, Cheng Dong, John W. Tierney, Lin Sun, Di Lu, Li Gui, Jian Yang, 2019, Acta Biomaterialia on p. 180-191

Effect of dose and release rate of CTGF and TGFβ3 on avascular meniscus healing

Solaiman Tarafder, Joseph Gulko, Daniel Kim, Kun Hee Sim, Shawn Gutman, Jian Yang, James L. Cook, Chang H. Lee, 2019, Journal of Orthopaedic Research on p. 1555-1562

Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression

Hua Wang, Haiyan Zhang, Qiuyi Sun, Jian Yang, Chun Zeng, Changhai Ding, Daozhang Cai, Anling Liu, Xiaochun Bai, 2019, Journal of Cellular Physiology on p. 2730-2740

Exosome Release Is Regulated by mTORC1

Wenchong Zou, Mingqiang Lai, Yue Zhang, Lei Zheng, Zhe Xing, Ting Li, Zhipeng Zou, Qiancheng Song, Xiaoyang Zhao, Laixin Xia, Jian Yang, Anling Liu, Han Zhang, Zhong Kai Cui, Yu Jiang, Xiaochun Bai, 2019, Advanced Science

Nanoparticle eluting-angioplasty balloons to treat cardiovascular diseases

Roshni Iyer, Aneetta E. Kuriakose, Serkan Yaman, Lee Chun Su, Dingying Shan, Jian Yang, Jun Liao, Liping Tang, Subhash Banerjee, Hao Xu, Kytai T. Nguyen, 2019, International Journal of Pharmaceutics on p. 212-223

Citrate-based materials fuel human stem cells by metabonegenic regulation

Chuying Ma, Xinggui Tian, Jimin P. Kim, Denghui Xie, Xiang Ao, Dingying Shan, Qiaoling Lin, Maria R. Hudock, Xiaochun Bai, Jian Yang, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. E11741-E11750

Engineered Healing of Avascular Meniscus Tears by Stem Cell Recruitment

Solaiman Tarafder, Joseph Gulko, Kun Hee Sim, Jian Yang, James L. Cook, Chang H. Lee, 2018, Scientific reports

Citrate chemistry and biology for biomaterials design

Chuying Ma, Ethan Gerhard, Di Lu, Jian Yang, 2018, Biomaterials on p. 383-400

The critical chemical and mechanical regulation of folic acid on neural engineering

Gloria B. Kim, Yongjie Chen, Weibo Kang, Jinshan Guo, Russell Payne, Hui Li, Qiong Wei, Julianne Baker, Cheng Dong, Sulin Zhang, Pak Kin Wong, Elias Rizk, Jiazhi Yan, Jian Yang, 2018, Biomaterials on p. 504-516

Bone and plasma citrate is reduced in osteoporosis

Hongdong Chen, Yeyang Wang, Huaiqian Dai, Xinggui Tian, Zhong Kai Cui, Zhenguo Chen, Le Hu, Qiancheng Song, Anling Liu, Zhiyong Zhang, Guozhi Xiao, Jian Yang, Yu Jiang, Xiaochun Bai, 2018, Bone on p. 189-197

Most-Cited Papers

Dual growth factor releasing multi-functional nanofibers for wound healing

Zhiwei Xie, Christian B. Paras, Hong Weng, Primana Punnakitikashem, Lee Chun Su, Khanh Vu, Liping Tang, Jian Yang, Kytai T. Nguyen, 2013, Acta Biomaterialia on p. 9351-9359

Three-dimensional manipulation of single cells using surface acoustic waves

Feng Guo, Zhangming Mao, Yuchao Chen, Zhiwei Xie, James P. Lata, Peng Li, Liqiang Ren, Jiayang Liu, Jian Yang, Ming Dao, Subra Suresh, Tony Jun Huang, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1522-1527

Citric acid-derived in situ crosslinkable biodegradable polymers for cell delivery

Dipendra Gyawali, Parvathi Nair, Yi Zhang, Richard T. Tran, Chi Zhang, Mikhail Samchukov, Marina Makarov, Harry K.W. Kim, Jian Yang, 2010, Biomaterials on p. 9092-9105

Synthesis and characterization of a biodegradable elastomer featuring a dual crosslinking mechanism

Richard T. Tran, Paul Thevenot, Dipendra Gyawali, Jung Chih Chiao, Liping Tang, Jian Yang, 2010, Soft Matter on p. 2449-2461

Engineering biodegradable polyester elastomers with antioxidant properties to attenuate oxidative stress in tissues

Robert van Lith, Elaine K. Gregory, Jian Yang, Melina R. Kibbe, Guillermo A. Ameer, 2014, Biomaterials on p. 8113-8122

A thermoresponsive biodegradable polymer with intrinsic antioxidant properties

Jian Yang, Robert Van Lith, Kevin Baler, Ryan A. Hoshi, Guillermo A. Ameer, 2014, Biomacromolecules on p. 3942-3952

Design strategies for fluorescent biodegradable polymeric biomaterials

Yi Zhang, Jian Yang, 2013, Journal of Materials Chemistry B on p. 132-148

Click chemistry plays a dual role in biodegradable polymer design

Jinshan Guo, Zhiwei Xie, Richard T. Tran, Denghui Xie, Dadi Jin, Xiaochun Bai, Jian Yang, 2014, Advanced Materials on p. 1906-1911

Development of intrinsically photoluminescent and photostable polylactones

Zhiwei Xie, Yi Zhang, Li Liu, Hong Weng, Ralph P. Mason, Liping Tang, Kytai T. Nguyen, Jer Tsong Hsieh, Jian Yang, 2014, Advanced Materials on p. 4491-4496

Dual-imaging enabled cancer-targeting nanoparticles

Aniket S. Wadajkar, Tejaswi Kadapure, Yi Zhang, Weina Cui, Kytai T. Nguyen, Jian Yang, 2012, Advanced Healthcare Materials on p. 450-456