Jian Yang
Huck Chair in Regenerative Engineering; Professor of Bioengineering

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W-340 Millennium Science Complex
University Park, PA 16802 - jxy30@psu.edu
- 814-865-1278
Research Summary
Development of new biodegradable polymers for use in engineering elastic tissues such as blood vessel, tendon, ligament, and cardiac tissue, and in other applications such as biological labeling, bioimaging and drug delivery.
Huck Affiliations
Links
Publication Tags
Tissue Nanoparticles Elastomers Citric Acid Composite Materials Antioxidants Polyurethanes Tissue Adhesives Tissue Engineering Tannins Electronic Equipment Oxidative Stress Adhesives Polymers Nanofibers Gastrodin Polyesters Silicon Intercellular Signaling Peptides And Proteins Transistors Blood Vessels Imaging Techniques Mechanical Properties Biodegradable Polymers BoneMost Recent Papers
Actin-ring segment switching drives nonadhesive gap closure
Qiong Wei, Xuechen Shi, Tiankai Zhao, Pingqiang Cai, Tianwu Chen, Yao Zhang, Changjin Huang, Jian Yang, Xiaodong Chen, Sulin Zhang, 2021, Proceedings of the National Academy of Sciences of the United States of America on p. 33263-33271
Syntheses and characterization of anti-thrombotic and anti-oxidative Gastrodin-modified polyurethane for vascular tissue engineering
Meng Zheng, Jiazhi Guo, Qing Li, Jian Yang, Yi Han, Hongcai Yang, Mali Yu, Lianmei Zhong, Di Lu, Limei Li, Lin Sun, 2021, Bioactive Materials on p. 404-419
A covalently cross-linked hyaluronic acid/bacterial cellulose composite hydrogel for potential biological applications
Shuo Tang, Kai Chi, Hui Xu, Qiang Yong, Jian Yang, Jeffrey M. Catchmark, 2021, Carbohydrate Polymers
High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma
Gloria B. Kim, Virginia Aragon-Sanabria, Lauren Randolph, Hali Jiang, Joshua A. Reynolds, Becky S. Webb, Achuthamangalam Madhankumar, Xiaojun Lian, James R. Connor, Jian Yang, Cheng Dong, 2020, Bioactive Materials on p. 624-635
Elastomeric polyurethane porous film functionalized with gastrodin for peripheral nerve regeneration
Qing Li, Limei Li, Mali Yu, Meng Zheng, Yao Li, Jian Yang, Min Dai, Lianmei Zhong, Lin Sun, Di Lu, 2020, Journal of Biomedical Materials Research - Part A on p. 1713-1725
Citrate-Based Tannin-Bridged Bone Composites for Lumbar Fusion
Jinshan Guo, Xinggui Tian, Denghui Xie, Kevin Rahn, Ethan Gerhard, Michelle Laurel Kuzma, Dongfang Zhou, Cheng Dong, Xiaochun Bai, Zhihui Lu, Jian Yang, 2020, Advanced Functional Materials
Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives
Xili Lu, Sanjun Shi, Hanmei Li, Ethan Gerhard, Zhihui Lu, Xinyu Tan, Wenliang Li, Kevin M. Rahn, Denghui Xie, Guodong Xu, Fang Zou, Xiaochun Bai, Jinshan Guo, Jian Yang, 2020, Biomaterials
Advances in bioresorbable electronics and uses in biomedical sensing
Michelle Kuzma, Ethan Gerhard, Dingying Shan, Jian Yang, 2020, on p. 29-72
Thermo-responsive fluorescent nanoparticles for multimodal imaging and treatment of cancers
Nikhil Pandey, Jyothi U. Menon, Masaya Takahashi, Jer Tsong Hsieh, Jian Yang, Kytai T. Nguyen, Aniket S. Wadajkar, 2020, Nanotheranostics on p. 1-13
Actin-ring segment switching drives nonadhesive gap closure
Qiong Wei, Xuechen Shi, Tiankai Zhao, Pingqiang Cai, Tianwu Chen, Yao Zhang, Changjin Huang, Jian Yang, X Chen, S Zhang, 2020, Proceedings of the National Academy of Sciences on p. 33263--33271
Most-Cited Papers
Three-dimensional manipulation of single cells using surface acoustic waves
Feng Guo, Zhangming Mao, Yuchao Chen, Zhiwei Xie, James P. Lata, Peng Li, Liqiang Ren, Jiayang Liu, Jian Yang, Ming Dao, Subra Suresh, Tony Jun Huang, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1522-1527
Injectable citrate-based mussel-inspired tissue bioadhesives with high wet strength for sutureless wound closure
Mohammadreza Mehdizadeh, Hong Weng, Dipendra Gyawali, Liping Tang, Jian Yang, 2012, Biomaterials on p. 7972-7983
Dual growth factor releasing multi-functional nanofibers for wound healing
Zhiwei Xie, Christian B. Paras, Hong Weng, Primana Punnakitikashem, Lee Chun Su, Khanh Vu, Liping Tang, Jian Yang, Kytai T. Nguyen, 2013, Acta Biomaterialia on p. 9351-9359
Design Strategies and Applications of Tissue Bioadhesives
Mohammadreza Mehdizadeh, Jian Yang, 2013, Macromolecular Bioscience on p. 271-288
Biodegradable elastomers and silicon nanomembranes/nanoribbons for stretchable, transient electronics, and biosensors
Suk Won Hwang, Chi Hwan Lee, Huanyu Cheng, Jae Woong Jeong, Seung Kyun Kang, Jae Hwan Kim, Jiho Shin, Jian Yang, Zhuangjian Liu, Guillermo A. Ameer, Yonggang Huang, John A. Rogers, 2015, Nano Letters on p. 2801-2808
Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems
Yixue Su, Zhiwei Xie, Gloria B. Kim, Cheng Dong, Jian Yang, 2015, ACS Biomaterials Science and Engineering on p. 201-217
Development of tannin-inspired antimicrobial bioadhesives
Jinshan Guo, Wei Sun, Jimin Peter Kim, Xili Lu, Qiyao Li, Min Lin, Oliver Mrowczynski, Elias Rizk, Juange Cheng, Guoying Qian, Jian Yang, 2018, Acta Biomaterialia on p. 35-44
Engineering biodegradable polyester elastomers with antioxidant properties to attenuate oxidative stress in tissues
Robert van Lith, Elaine K. Gregory, Jian Yang, Melina R. Kibbe, Guillermo A. Ameer, 2014, Biomaterials on p. 8113-8122
A thermoresponsive biodegradable polymer with intrinsic antioxidant properties
Jian Yang, Robert Van Lith, Kevin Baler, Ryan A. Hoshi, Guillermo A. Ameer, 2014, Biomacromolecules on p. 3942-3952
Design and application of magnetic-based theranostic nanoparticle systems
Aniket S. Wadajkar, Jyothi U. Menon, Tejaswi Kadapure, Richard T. Tran, Jian Yang, Kytai T. Nguyen, 2013, Recent Patents on Biomedical Engineering on p. 47-57
News Articles Featuring Jian Yang
Oct 21, 2020
Novel bioresorbable, tissue-healing surgical device approved by FDA
A new surgical tendon fixation system that not only re-attaches damaged tissues but also facilitates healing as it is absorbed by the body has been granted 510(k) clearance by the U.S. Food and Drug Administration, indicating that the device is “as safe and effective” as other legally marketed devices and is ready to go to market.
Full Article
Feb 03, 2020
Academia-enterprise partnership aims to help people with diabetes
Innovative wound dressing would help reduce life-threatening infections, amputations for diabetic patients.
Full Article