Jessica Grembi
Assistant Professor of Pharmacology
-
306B Huck Life Sciences
University Park, PA - She/Her
- jag548@psu.edu
Research Summary
The biological mechanisms underlying persistent childhood undernutrition
Huck Affiliations
Links
Most Recent Publications
Biomarkers of environmental enteric dysfunction and neurodevelopmental outcomes among children in rural Bangladesh and Kenya: a prospective cohort study
Gene Ho, Beryl Achando, Shahjahan Ali, Caitlin Hemlock, Helen Pitchik, Christine Stewart, Fahmida Tofail, Md. Ziaur Rahman, Mohammad Allaudin, Gouthami Rao, Holly Dentz, John Buleti, Cecilia Nekesa, Charles Arnold, Syeda Famida, Md. Saheen Hossen, Palash Mutsuddi, Salma Akter, Jessica Grembi, Soophia Tan, Sarah Allaudin, Theodora Meerkerk, Marlene Wolfe, Priscah Cheruiyot, Sammy Njenga, Abul Shoab, Mahbubur Rahman, Leanne Unicomb, Benjamin Arnold, Patricia Kariger, Alan Hubbard, John Colford, Jr., Amy Pickering, Clair Null, Stephen Luby, Lia Fernald, Andrew Mertens, Audrie Lin, 2025, American Journal of Clinical Nutrition
Pathways through which water, sanitation, hygiene, and nutrition interventions reduce antibiotic use in young children: a mediation analysis of a cohort nested within a cluster-randomized trial
A Nguyen, G Heitmann, A Mertens, S Ashraf, M Rahman, S Ali, M Rahman, B Arnold, Jessica Grembi, A Lin, A Ercumen, J Benjamin-Chung, 2025, EClinicalMedicine on p. 103147
Treatment heterogeneity of water, sanitation, hygiene, and nutrition interventions on child growth by environmental enteric dysfunction and pathogen status for young children in Bangladesh
Z Butzin-Dozier, Yunwen Ji, J Coyle, I Malenica, E Rogawski McQuade, Jessica Grembi, J Platts-Mills, E Houpt, J Graham, Shahjahan Ali, Md. Ziaur Rahman, M Alauddin, S Famida, S Akther, M Hossen, P Mutsuddi, A Shoab, Mahbubur Rahman, Md. Ohedul Islam, R Miah, M Taniuchi, Jie Liu, S Alauddin, C Stewart, S Luby, J Colford, Jr, A Hubbard, A Mertens, Audrie Lin, 2025, PLoS Neglected Tropical Diseases on p. e0012881
Water, sanitation, handwashing, and nutritional interventions can reduce child antibiotic use: evidence from Bangladesh and Kenya
A Ercumen, A Mertens, Z Butzin-Dozier, D Jung, Shahjahan Ali, B Achando, G Rao, C Hemlock, A Pickering, C Stewart, Sophia Tan, Jessica Grembi, J Benjamin-Chung, M Wolfe, G Ho, Md. Ziaur Rahman, C Arnold, H Dentz, S Njenga, T Meerkerk, B Chen, M Nadimpalli, Md. Ohedul Islam, A Hubbard, C Null, L Unicomb, Mahbubur Rahman, J Colford, Jr, S Luby, Benjamin Arnold, Audrie Lin, 2025, Nature Communications on p. 556
Associations between weather extremes and faecal contamination along pathogen transmission pathways in rural Bangladeshi households: a prospective observational study
C Niven, Mahfuza Islam, A Nguyen, Jessica Grembi, A Mertens, A Pickering, L Kwong, M Alam, D Sen, S Islam, Mahbubur Rahman, L Unicomb, A Hubbard, S Luby, J Colford, Jr, Benjamin Arnold, J Benjamin-Chung, A Ercumen, 2025, The Lancet Planetary Health on p. e5-e13
Influence of hydrometeorological risk factors on child diarrhea and enteropathogens in rural Bangladesh
Jessica Grembi, A Nguyen, M Riviere, G Heitmann, A Patil, T Athni, S Djajadi, A Ercumen, A Lin, Y Crider, A Mertens, M Karim, M Islam, R Miah, S Famida, M Hossen, P Mutsuddi, S Ali, M Rahman, Z Hussain, A Shoab, R Haque, M Rahman, L Unicomb, S Luby, B Arnold, A Bennett, J Benjamin-Chung, 2024, PLoS Neglected Tropical Diseases on p. e0012157
Influence of temperature and precipitation on the effectiveness of water, sanitation, and handwashing interventions against childhood diarrheal disease in rural bangladesh: A reanalysis of the WASH benefits Bangladesh trial
A Nguyen, Jessica Grembi, M Riviere, G Barratt Heitmann, W Hutson, T Athni, A Patil, A Ercumen, Audrie Lin, Y Crider, A Mertens, L Unicomb, Mahbubur Rahman, S Luby, Benjamin Arnold, J Benjamin-Chung, 2024, Environmental Health Perspectives on p. 47006
Is detection of enteropathogens and human or animal faecal markers in the environment associated with subsequent child enteric infections and growth: an individual participant data meta-analysis
A Mertens, Benjamin Arnold, J Benjamin-Chung, A Boehm, J Brown, D Capone, T Clasen, E Fuhrmeister, Jessica Grembi, D Holcomb, J Knee, L Kwong, Audrie Lin, S Luby, R Nala, K Nelson, S Njenga, C Null, A Pickering, Mahbubur Rahman, H Reese, L Steinbaum, J Stewart, R Thilakaratne, O Cumming, J Colford, Jr, A Ercumen, 2024, The Lancet Global Health on p. e433-e444
Human metabolome variation along the upper intestinal tract
J Folz, R Culver, J Morales, Jessica Grembi, G Triadafilopoulos, D Relman, K Huang, D Shalon, O Fiehn, 2023, Nature Metabolism on p. 777-788
Introducing riskCommunicator: An R package to obtain interpretable effect estimates for public health
Jessica Grembi, E Rogawski McQuade, 2022, PLoS One on p. e0265368
Most-Cited Papers
Human metabolome variation along the upper intestinal tract
J Folz, R Culver, J Morales, Jessica Grembi, G Triadafilopoulos, D Relman, K Huang, D Shalon, O Fiehn, 2023, Nature Metabolism on p. 777-788
Gut microbiota plasticity is correlated with sustained weight loss on a low-carb or low-fat dietary intervention
Jessica Grembi, L Nguyen, T Haggerty, C Gardner, S Holmes, J Parsonnet, 2020, Scientific Reports on p. 1405
Introducing riskCommunicator: An R package to obtain interpretable effect estimates for public health
Jessica Grembi, E Rogawski McQuade, 2022, PLoS One on p. e0265368
Identification of Widespread Antibiotic Exposure in Patients with Cholera Correlates with Clinically Relevant Microbiota Changes
L Alexandrova, F Haque, P Rodriguez, A Marrazzo, Jessica Grembi, V Ramachandran, A Hryckowian, C Adams, Siddique MSA, A Khan, F Qadri, J Andrews, Mahmudur Rahman, A Spormann, G Schoolnik, A Chien, Eric Nelson, 2019, Journal of Infectious Diseases on p. 1655-1666
Gold standard cholera diagnostics are tarnished by lytic bacteriophage and antibiotics
Eric Nelson, Jessica Grembi, D Chao, J Andrews, L Alexandrova, P Rodriguez, V Ramachandran, M Sayeed, J Wamala, A Debes, D Sack, A Hryckowian, F Haque, S Khatun, M Rahman, A Chien, A Spormann, G Schoolnik, 2020, Journal of Clinical Microbiology
Is detection of enteropathogens and human or animal faecal markers in the environment associated with subsequent child enteric infections and growth: an individual participant data meta-analysis
A Mertens, Benjamin Arnold, J Benjamin-Chung, A Boehm, J Brown, D Capone, T Clasen, E Fuhrmeister, Jessica Grembi, D Holcomb, J Knee, L Kwong, Audrie Lin, S Luby, R Nala, K Nelson, S Njenga, C Null, A Pickering, Mahbubur Rahman, H Reese, L Steinbaum, J Stewart, R Thilakaratne, O Cumming, J Colford, Jr, A Ercumen, 2024, The Lancet Global Health on p. e433-e444
High-Throughput Multiparallel Enteropathogen Detection via Nano-Liter qPCR
Jessica Grembi, K Mayer-Blackwell, S Luby, A Spormann, 2020, Frontiers in cellular and infection microbiology on p. 351
Shared bacterial communities between soil, stored drinking water, and hands in rural Bangladeshi households
E Fuhrmeister, A Ercumen, Jessica Grembi, Mahfuza Islam, A Pickering, Kara Nelson, 2020, Water Research X on p. 100056
Influence of temperature and precipitation on the effectiveness of water, sanitation, and handwashing interventions against childhood diarrheal disease in rural bangladesh: A reanalysis of the WASH benefits Bangladesh trial
A Nguyen, Jessica Grembi, M Riviere, G Barratt Heitmann, W Hutson, T Athni, A Patil, A Ercumen, Audrie Lin, Y Crider, A Mertens, L Unicomb, Mahbubur Rahman, S Luby, Benjamin Arnold, J Benjamin-Chung, 2024, Environmental Health Perspectives on p. 47006
High-throughput low-cost nl-qPCR for enteropathogen detection: A proof-ofconcept among hospitalized patients in Bangladesh
K Flaherty, Jessica Grembi, V Ramachandran, F Haque, S Khatun, Mahmudu Rahman, S Maples, T Becker, A Spormann, G Schoolnik, A Hryckowian, Eric Nelson, 2021, PLoS One on p. e0257708