Jan McAllister

Professor of Cellular and Molecular Physiology

Jan McAllister

Huck Affiliations

    Molecular Medicine

Publication Tags

Polycystic Ovary Syndrome Androgens Theca Cells Genes Messenger Rna Gene Expression Cholesterol Cholesterol Side Chain Cleavage Enzyme Proteins Alternative Splicing Cells Protein Isoforms Phenotype Genome Ovary Stromal Cells Racemases And Epimerases Rna Stability Insulin Resistance Mice Micrornas Ovaries Cleavage (Chemistry) Inositol Steroids

Most Recent Papers

Human dennd1a.V2 drives cyp17a1 expression and androgen production in mouse ovaries and adrenals

Maria E. Teves, Bhavi P. Modi, Rewa Kulkarni, Angela X. Han, Jamaia S. Marks, Mark A. Subler, Jolene Windle, Jordan M. Newall, Jan M. McAllister, Jerome F. Strauss, 2020, International Journal of Molecular Sciences

Colocalization of polycystic ovary syndrome candidate gene products in theca cells suggests novel signaling pathways

Rewa Kulkarni, Maria E. Teves, Angela X. Han, Jan M. McAllister, Jerome F. Strauss, 2019, Journal of the Endocrine Society on p. 2204-2223

MiRNA profiling reveals miRNA-130b-3p mediates DENND1A Variant 2 expression and androgen biosynthesis

Jan M. Mcallister, Angela X. Han, Bhavi P. Modi, Maria E. Teves, Grace R. Mavodza, Zachary L. Anderson, Tsaiwei Shen, Lane K. Christenson, Kellie J. Archer, Jerome F. Strauss, 2019, Endocrinology on p. 1964-1981

VCAM1 is induced in ovarian theca and stromal cells in a mouse model of androgen excess

Nicholes R. Candelaria, Achuth Padmanabhan, Fabio Stossi, M. Cecilia Ljungberg, Katharine E. Shelly, Braden K. Pew, Minerva Solis, Ayane M. Rossano, Jan M. McAllister, Sheng Wu, Jo Anne S. Richards, 2019, Endocrinology on p. 1377-1393

Alternative splicing of DENND1A, a PCOS candidate gene, generates variant 2

Meng Kian Tee, Mart Speek, Balázs Legeza, Bhavi Modi, Maria Eugenia Teves, Janette M. McAllister, Jerome F. Strauss, Walter L. Miller, 2016, Molecular and Cellular Endocrinology on p. 25-35

Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype

Jan M. McAllister, Bhavi Modi, Bruce A. Miller, Jessica Biegler, Richard Bruggeman, Richard S. Legro, Jerome F. Strauss, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. E1519-E1527

Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls

Douglas Heimark, Jan McAllister, Joseph Larner, 2014, Endocrine Journal on p. 111-117

The genetics of polycystic ovary syndrome

J. M. McAllister, J. F. Strauss, 2013, Giornale Italiano di Ostetricia e Ginecologia on p. 68-70

Cholesterol side-chain cleavage gene expression in theca cells: Augmented transcriptional regulation and mRNA stability in polycystic ovary syndrome.

Jessica K. Wickenheisser, Jessica M. Biegler, Velen L. Nelson-DeGrave, Richard S. Legro, Jerome F. Strauss, Jan M. McAllister, 2012, PLoS One

Family-based analysis of candidate genes for polycystic ovary syndrome

Kathryn G. Ewens, Douglas R. Stewart, Wendy Ankener, Margrit Urbanek, Jan M. McAllister, K. Maravet Baig, Stephen C.J. Parker, Elliot H. Margulies, Richard S. Legro, Andrea Dunaif, Jerome F. Strauss, Richard S. Spielman, 2010, Journal of Clinical Endocrinology and Metabolism on p. 2306-2315

Most-Cited Papers

Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype

Jan M. McAllister, Bhavi Modi, Bruce A. Miller, Jessica Biegler, Richard Bruggeman, Richard S. Legro, Jerome F. Strauss, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. E1519-E1527

Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls

Douglas Heimark, Jan McAllister, Joseph Larner, 2014, Endocrine Journal on p. 111-117

Cholesterol side-chain cleavage gene expression in theca cells: Augmented transcriptional regulation and mRNA stability in polycystic ovary syndrome.

Jessica K. Wickenheisser, Jessica M. Biegler, Velen L. Nelson-DeGrave, Richard S. Legro, Jerome F. Strauss, Jan M. McAllister, 2012, PLoS One

Alternative splicing of DENND1A, a PCOS candidate gene, generates variant 2

Meng Kian Tee, Mart Speek, Balázs Legeza, Bhavi Modi, Maria Eugenia Teves, Janette M. McAllister, Jerome F. Strauss, Walter L. Miller, 2016, Molecular and Cellular Endocrinology on p. 25-35

MiRNA profiling reveals miRNA-130b-3p mediates DENND1A Variant 2 expression and androgen biosynthesis

Jan M. Mcallister, Angela X. Han, Bhavi P. Modi, Maria E. Teves, Grace R. Mavodza, Zachary L. Anderson, Tsaiwei Shen, Lane K. Christenson, Kellie J. Archer, Jerome F. Strauss, 2019, Endocrinology on p. 1964-1981

Colocalization of polycystic ovary syndrome candidate gene products in theca cells suggests novel signaling pathways

Rewa Kulkarni, Maria E. Teves, Angela X. Han, Jan M. McAllister, Jerome F. Strauss, 2019, Journal of the Endocrine Society on p. 2204-2223

Human dennd1a.V2 drives cyp17a1 expression and androgen production in mouse ovaries and adrenals

Maria E. Teves, Bhavi P. Modi, Rewa Kulkarni, Angela X. Han, Jamaia S. Marks, Mark A. Subler, Jolene Windle, Jordan M. Newall, Jan M. McAllister, Jerome F. Strauss, 2020, International Journal of Molecular Sciences

VCAM1 is induced in ovarian theca and stromal cells in a mouse model of androgen excess

Nicholes R. Candelaria, Achuth Padmanabhan, Fabio Stossi, M. Cecilia Ljungberg, Katharine E. Shelly, Braden K. Pew, Minerva Solis, Ayane M. Rossano, Jan M. McAllister, Sheng Wu, Jo Anne S. Richards, 2019, Endocrinology on p. 1377-1393

The genetics of polycystic ovary syndrome

J. M. McAllister, J. F. Strauss, 2013, Giornale Italiano di Ostetricia e Ginecologia on p. 68-70