James Adair

Professor of Material Science and Engineering

205 Steidle
University Park, PA
jha3@psu.edu
814-863-6047

Research Summary

Nanoscale materials and phenomena for biological, optical and structural applications, property manipulation via novel chemical pathways for designer particles and materials, colloid and interfacial chemistry, powder characterization, powder processing, and commercialization and regulatory pathways for nanomedical human healthcare formulations

Huck Institutes Affiliations

Publication Tags

Nanoparticles Calcium Phosphate Calcium Nanocomposites Cells Tumors Imaging Techniques Drug Delivery Cancer Polymers Molecules Composite Materials Encapsulation Calcium Phosphates Pharmaceutical Preparations Phosphates Drugs Fluorophores Delivery Coatings Indocyanine Green Breast Toxicity Photodynamic Therapy Kinetics

Most Recent Papers

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Welley S. Loc, Samuel S. Linton, Zachary R. Wilczynski, Gail L. Matters, Christopher O. McGovern, Thomas Abraham, Todd Fox, Christopher M. Gigliotti, Xiaomeng Tang, Amra Tabakovic, Jo Ann Martin, Gary A. Clawson, Jill P. Smith, Peter J. Butler, Mark Kester, James H. Adair, 2017, Nanomedicine: Nanotechnology, Biology, and Medicine on p. 2313-2324

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Gary A. Clawson, Thomas Abraham, Weihua Pan, Xiaomeng Tang, Samuel S. Linton, Christopher O. McGovern, Welley S. Loc, Jill P. Smith, Peter J. Butler, Mark Kester, James H. Adair, Gail L. Matters, 2017, Nucleic Acid Therapeutics on p. 23-35

3D Printing of Personalized Artificial Bone Scaffolds

Shailly H. Jariwala, Gregory S. Lewis, Zachary J. Bushman, James H. Adair, Henry J. Donahue, 2015, 3D Printing and Additive Manufacturing on p. 56-64

Synthesis of calcium carbonate particles in octylamine/water bilayer systems

Jun Wang, William B. White, James H. Adair, 2014, Bulletin de l'Institut Scientifique, Section Sciences de la Terre on p. 156-162

PhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphate

Brian M. Barth, Sriram S. Shanmugavelandy, James M. Kaiser, Christopher McGovern, Erhan Ii Altinoǧlu, Jeremy K. Haakenson, Jeremy A. Hengst, Evan L. Gilius, Sarah A. Knupp, Todd E. Fox, Jill P. Smith, Timothy M. Ritty, James H. Adair, Mark Kester, 2013, ACS Nano on p. 2132-2144

Gold cluster coatings enhancing Raman scattering from surfaces

Zhixun Luo, Jordan C. Smith, Trevor M. Goff, James H. Adair, A. W. Castleman, 2013, Chemical Physics on p. 73-78

Formation and characterization of nano-sized RDX particles produced using the RESS-AS process

Jonathan T. Essel, Andrew C. Cortopassi, Kenneth K. Kuo, Christopher G. Leh, James H. Adair, 2012, Propellants, Explosives, Pyrotechnics on p. 699-706

Design of contact-aided compliant cellular mechanisms with curved walls

Samantha A. Cirone, Gregory R. Hayes, Brian L. Babcox, Mary Frecker, James H. Adair, George A. Lesieutre, 2012, Journal of Intelligent Material Systems and Structures on p. 1773-1785

Robust parameter design for multiple-stage nanomanufacturing

Chumpol Yuangyai, Harriet Black Nembhard, Gregory Hayes, James H. Adair, 2012, IIE Transactions (Institute of Industrial Engineers) on p. 580-589

SiAlON ceramics from preceramic polymers and nano-sized fillers

E. Bernardo, G. Parcianello, P. Colombo, J. H. Adair, A. T. Barnes, J. R. Hellmann, B. H. Jones, J. Kruise, J. J. Swab, 2012, Journal of the European Ceramic Society on p. 1329-1335

High-Impact Papers

Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer

Erhan I. Altinoǧlu, Timothy J. Russin, James M. Kaiser, Brian M. Barth, Peter C. Eklund, Mark Kester, James H. Adair, 2008, ACS Nano on p. 2075-2084

Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery

Thomas T. Morgan, Hari S. Muddana, Erhan I. Altinoǧlu, Sarah M. Rouse, Amra Tabaković, Tristan Tabouillot, Timothy J. Russin, Sriram S. Shanmugavelandy, Peter J. Butler, Peter C. Eklund, Jong K. Yun, Mark Kester, James H. Adair, 2008, Nano Letters on p. 4108-4115

Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer Cells

Mark Kester, Yasser Heakal, Todd Fox, Arati Sharma, Gavin P. Robertson, Thomas T. Morgan, Erhan I. Altinoǧlu, Amra Tabaković, Mylisa R. Parette, Sarah M. Rouse, Victor Ruiz-Velasco, James H. Adair, 2008, Nano Letters on p. 4116-4121

Targeting <sup>V600E</sup>B-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development

Melissa A. Tran, Raghavendra Gowda, Arati Sharma, Eun Joo Park, James Adair, Mark Kester, Nadine Barrie Smith, Gavin P. Robertson, 2008, Cancer Research on p. 7638-7649

Nanoparticulate alternatives for drug delivery

James H. Adair, Mylisa P. Parette, Erhan I. Altinoǧlu, Mark Kester, 2010, ACS Nano on p. 4967-4970

Photophysics of Cy3-encapsulated calcium phosphate nanoparticles

Hari S. Muddana, Thomas T. Morgan, James H. Adair, Peter J. Butler, 2009, Nano Letters on p. 1559-1566

Targeted indocyanine-green-loaded calcium phosphosilicate nanoparticles for in vivo photodynamic therapy of leukemia

Brian M. Barth, Erhan I. Altinoǧlu, Sriram S. Shanmugavelandy, James M. Kaiser, Daniza Crespo-Gonzalez, Nicole A. Divittore, Christopher McGovern, Trevor M. Goff, Nicole R. Keasey, James H. Adair, Thomas P. Loughran, David F. Claxton, Mark Kester, 2011, ACS Nano on p. 5325-5337

Bioconjugation of calcium phosphosilicate composite nanoparticles for selective targeting of human breast and pancreatic cancers in vivo

Brian M. Barth, Rahul Sharma, Erhan I. Altinoǧlu, Thomas T. Morgan, Sriram S. Shanmugavelandy, James M. Kaiser, Christopher McGovern, Gail L. Matters, Jill P. Smith, Mark Kester, James H. Adair, 2010, ACS Nano on p. 1279-1287

X-ray diffraction and H-storage in ultra-small palladium particles

D. G. Narehood, S. Kishore, H. Goto, J. H. Adair, J. A. Nelson, H. R. Gutiérrez, P. C. Eklund, 2009, International Journal of Hydrogen Energy on p. 952-960

Calcium phosphate-based composite nanoparticles in bioimaging and therapeutic delivery applications

Amra Tabaković, Mark Kester, James H. Adair, 2012, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology on p. 96-112