Jack Vanden Heuvel

Director of the Center for Excellence in Nutrigenomics; Professor of Molecular Toxicology

Jack Vanden Heuvel

Research Summary

Mechanisms of action of hypolipidemic drugs and peroxisome proliferators; steroid hormone receptor-mediated signal transduction; signal transduction by lipids and fatty acids; receptor-mediated carcinogenesis.

Huck Affiliations

Links

Most Recent Publications

J Bisanz, Bipin Rimal, Stephanie Collins, Emily Weinert, Ceylan Tanes, A Patterson, Megan Granda, Imhoi Koo, E Rocha, Sumeet Solanka, M Granda, Nushrat Hoque, Sumeet Solanki, Nushrat Hoque, Emily Gentry, Emily Gentry, Tingting Yan, Imhoi Koo, Erin Reilly, Kristopher Krausz, Dhimant Desai, Fuhua Hao, Shantu Amin, Devendra Paudel, Edson Rocha, Vishal Singh, James Coleman, Tingting Yan, Yatrik Shah, Min Kim, Kyle Bittinger, Frank Gonzalez, John Vanden Heuvel, Joseph Zackular, Kristopher Krausz, A Patterson, Dhimant Desai, Shantu Amin, James Coleman, Yatrik Shah, Jordan Bisanz, Frank Gonzalez, John Heuvel, John P. Vanden Heuvel, Gary Wu, Babette Zemel, Pieter Dorrestein, Andrew Patterson, 2024, Nature on p. 859-868

John P. Vanden Heuvel, Megan Granda, Francesca Ferguson, Scott R. Glaberman, Heather E. Preisendanz, 2024, Science of the Total Environment on p. 176115

James Farnan, John P. Vanden Heuvel, Frank L. Dorman, Nathaniel R. Warner, William D. Burgos, 2023, Environmental Pollution

John P. Vanden Heuvel, Shuling Zhou, Anisha B. Patel, Harry N. Kamerow, Peter Baran, John P. Ford, 2023, BioMed Research International

Kun Ming Chen, Henry Thompson, John P. Vanden-Heuvel, Yuan Wan Sun, Neil Trushin, Cesar Aliaga, Krishne Gowda, Shantu Amin, Bruce Stanley, Andrea Manni, Karam El-Bayoumy, 2021, Scientific Reports

Javahar Kohli Mariwala, Deshanie Rai, Muralidhara Padigaru, Abhijeet Ashok Morde, Ewa Maddox, Samar Maalouf, Kayla Smith, John P. Vanden Heuvel, 2021, Food Science and Nutrition on p. 2823-2835

Detection and removal of biologically active organic micropollutants from hospital wastewater

Luis Castillo Meza, Paulina Piotrowski, James Farnan, Travis Tasker, Boya Xiong, Benedikt Weggler, Kyra Murrell, Franklin Lewis Dorman, Jr., F Dorman, John P. Vanden Heuvel, William Burgos, 2020, Science of the Total Environment on p. 134469 (8)

Environmental and Human Health Impacts of Spreading Oil and Gas Wastewater on Roads

T. L. Tasker, W. D. Burgos, P. Piotrowski, L. Castillo-Meza, T. A. Blewett, K. B. Ganow, A. Stallworth, P. L.M. Delompré, G. G. Goss, L. B. Fowler, J. P. Vanden Heuvel, F. Dorman, N. R. Warner, 2018, Environmental Science & Technology on p. 7081-7091

Xiaoran Liu, Josephine Garban, Peter J. Jones, Jack Vanden Heuvel, Benoît Lamarche, David J. Jenkins, Philip W. Connelly, Patrick Couture, Shuaihua Pu, Jennifer A. Fleming, Sheila G. West, Penny M. Kris-Etherton, 2018, Journal of Nutrition on p. 721-728

John P. Vanden Heuvel, Ewa Maddox, Samar W. Maalouf, Elizabeth Iorns, Rachel Tsui, Alexandria Denis, Nicole Perfito, Timothy M. Errington, 2018, eLife

Most-Cited Papers

Terry D. Hinds, Katherine A. Burns, Peter A. Hosick, Lucien McBeth, Andrea Nestor-Kalinoski, Heather A. Drummond, Abdulhadi A. Alamodi, Michael W. Hankins, John P. Vanden Heuvel, David E. Stec, 2016, Journal of Biological Chemistry on p. 25179-25191

J Bisanz, Bipin Rimal, Stephanie Collins, Emily Weinert, Ceylan Tanes, A Patterson, Megan Granda, Imhoi Koo, E Rocha, Sumeet Solanka, M Granda, Nushrat Hoque, Sumeet Solanki, Nushrat Hoque, Emily Gentry, Emily Gentry, Tingting Yan, Imhoi Koo, Erin Reilly, Kristopher Krausz, Dhimant Desai, Fuhua Hao, Shantu Amin, Devendra Paudel, Edson Rocha, Vishal Singh, James Coleman, Tingting Yan, Yatrik Shah, Min Kim, Kyle Bittinger, Frank Gonzalez, John Vanden Heuvel, Joseph Zackular, Kristopher Krausz, A Patterson, Dhimant Desai, Shantu Amin, James Coleman, Yatrik Shah, Jordan Bisanz, Frank Gonzalez, John Heuvel, John P. Vanden Heuvel, Gary Wu, Babette Zemel, Pieter Dorrestein, Andrew Patterson, 2024, Nature on p. 859-868

Environmental and Human Health Impacts of Spreading Oil and Gas Wastewater on Roads

T. L. Tasker, W. D. Burgos, P. Piotrowski, L. Castillo-Meza, T. A. Blewett, K. B. Ganow, A. Stallworth, P. L.M. Delompré, G. G. Goss, L. B. Fowler, J. P. Vanden Heuvel, F. Dorman, N. R. Warner, 2018, Environmental Science & Technology on p. 7081-7091

Detection and removal of biologically active organic micropollutants from hospital wastewater

Luis Castillo Meza, Paulina Piotrowski, James Farnan, Travis Tasker, Boya Xiong, Benedikt Weggler, Kyra Murrell, Franklin Lewis Dorman, Jr., F Dorman, John P. Vanden Heuvel, William Burgos, 2020, Science of the Total Environment on p. 134469 (8)

John P. Vanden Heuvel, Ewa Maddox, Samar W. Maalouf, Elizabeth Iorns, Rachel Tsui, Alexandria Denis, Nicole Perfito, Timothy M. Errington, 2018, eLife

Xiaoran Liu, Josephine Garban, Peter J. Jones, Jack Vanden Heuvel, Benoît Lamarche, David J. Jenkins, Philip W. Connelly, Patrick Couture, Shuaihua Pu, Jennifer A. Fleming, Sheila G. West, Penny M. Kris-Etherton, 2018, Journal of Nutrition on p. 721-728

Daniel B. Hannon, Jerry T. Thompson, Christina Khoo, Vijaya Juturu, John P. Vanden Heuvel, 2017, Food Science and Nutrition on p. 148-159

Kun Ming Chen, Henry Thompson, John P. Vanden-Heuvel, Yuan Wan Sun, Neil Trushin, Cesar Aliaga, Krishne Gowda, Shantu Amin, Bruce Stanley, Andrea Manni, Karam El-Bayoumy, 2021, Scientific Reports

Javahar Kohli Mariwala, Deshanie Rai, Muralidhara Padigaru, Abhijeet Ashok Morde, Ewa Maddox, Samar Maalouf, Kayla Smith, John P. Vanden Heuvel, 2021, Food Science and Nutrition on p. 2823-2835

John P. Vanden Heuvel, Jessica Bullenkamp, Elizabeth Iorns, William Gunn, Fraser Tan, Joelle Lomax, Nicole Perfito, Timothy Errington, 2016, eLife

News Articles Featuring Jack Vanden Heuvel

‘Forever chemicals’ detected in 65% of sampled private wells in Pennsylvania

Researchers find 18% of sampled wells have PFAS levels beyond drinking water standards; compounds detected most often, and in the highest concentrations, in wells in the southeastern part of the state.

Abortion restriction based on environmental impacts fails in Montana

A Montana bill to restrict abortion medicine based on effects on the environment fails on a tied vote in 2025.

‘Using the devil’s own tools against them': Abortion opponents turn to environmental laws

Several states are trying to curtail abortion medication by claiming mifepristone could contaminate drinking water.

Alternate stream water-testing method detects emerging contaminants

In a study on central Pennsylvania streams, a new way of analyzing water quality reveals chemicals from pesticides, pharmaceuticals and personal care products.

New role for bacterial enzyme in gut metabolism revealed

Bile acids long have been known to play a role in human metabolism. Synthesized from cholesterol in the liver, bile acids are involved in digestive processes, particularly in absorbing fat.

The EPA doesn’t require safety tests for most chemicals, including the three that spilled into a Delaware River tributary

The EPA doesn’t require safety tests for most chemicals, including the three that spilled into a Delaware River tributary