J. Martin Bollinger

Professor of Chemistry; Professor of Biochemistry and Molecular Biology

J. Martin Bollinger

Research Summary

Mechanisms of metalloenzymes and metallofactor assembly

Huck Affiliations

Links

Publication Tags

Iron Enzymes Oxygenases Hydrogen Substrates Proteins Aldehyde Decarbonylase Formic Acid Hydroxylation Aldehydes Tyrosine Dioxygenases Electrons Oxidoreductases Fatty Aldehyde Atoms Fatty Acids Oxidation Reduction Oxygen Taurine Biosynthesis Decarboxylation Glutarates Carbon Monoxide Carbon

Most Recent Papers

Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the <i>N</i>-nitrosourea-producing enzyme SznF.

M McBride, S Pope, Kebin Hu, C Denise Okafor, E Balskus, J Bollinger, Jr, Amie Boal, 2021, Proceedings of the National Academy of Sciences of the United States of America

Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase

Gang Liu, Debangsu Sil, Nunziata Maio, Wing Hang Tong, J. Martin Bollinger, Carsten Krebs, Tracey Ann Rouault, 2020, Nature Communications

Nuclear Resonance Vibrational Spectroscopic Definition of the Facial Triad Fe<sup>IV</sup>═O Intermediate in Taurine Dioxygenase: Evaluation of Structural Contributions to Hydrogen Atom Abstraction.

M Srnec, S Iyer, Dassama LMK, K Park, Terrie Wong, K Sutherlin, Y Yoda, Y Kobayashi, M Kurokuzu, M Saito, M Seto, Carsten Krebs, Joseph Bollinger, E Solomon, 2020, Journal of the American Chemical Society on p. 18886-18896

A peroxodiiron(III/III) intermediate mediating both n-hydroxylation steps in biosynthesis of the n-nitrosourea pharmacophore of streptozotocin by the multi-domain metalloenzyme SznF

Molly J. McBride, Debangsu Sil, Tai L. Ng, Anne Marie Crooke, Grace E. Kenney, Christina R. Tysoe, Bo Zhang, Emily P. Balskus, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, 2020, Journal of the American Chemical Society on p. 11818-11828

Lifetimes of the Aglycone Substrates of Specifier Proteins, the Autonomous Iron Enzymes That Dictate the Products of the Glucosinolate-Myrosinase Defense System in Brassica Plants.

L Mocniak, Keith Elkin, Joseph Bollinger, 2020, Biochemistry on p. 2432-2441

High-resolution iron X-ray absorption spectroscopic and computational studies of non-heme diiron peroxo intermediates

George E. Cutsail, Elizabeth J. Blaesi, Christopher J. Pollock, J. Martin Bollinger, Carsten Krebs, Serena DeBeer, 2020, Journal of Inorganic Biochemistry

Structure of a Ferryl Mimic in the Archetypal Iron(II)- And 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD

Katherine M. Davis, Madison Altmyer, Ryan J. Martinie, Irene Schaperdoth, Carsten Krebs, J. Martin Bollinger, Amie K. Boal, 2019, Biochemistry on p. 4218-4223

Substrate-triggered formation of a peroxo-Fe<sub>2</sub>(III/III) intermediate during fatty acid decarboxylation by UndA

Bo Zhang, Lauren J. Rajakovich, Devon Van Cura, Elizabeth J. Blaesi, Andrew J. Mitchell, Christina R. Tysoe, Xuejun Zhu, Bennett R. Streit, Zhe Rui, Wenjun Zhang, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, 2019, Journal of the American Chemical Society on p. 14510-14514

Hydrogen donation but not abstraction by a tyrosine (Y68) during endoperoxide Installation by verruculogen synthase (FtmOx1)

Noah P. Dunham, José M. Del Río Pantoja, Bo Zhang, Lauren J. Rajakovich, Benjamin D. Allen, Carsten Krebs, Amie K. Boal, J. Martin Bollinger, 2019, Journal of the American Chemical Society on p. 9964-9979

A new microbial pathway for organophosphonate degradation catalyzed by two previously misannotated non-heme-iron oxygenases

Lauren J. Rajakovich, Maria Eirini Pandelia, Andrew J. Mitchell, Wei Chen Chang, Bo Zhang, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, 2019, Biochemistry on p. 1627-1647

Most-Cited Papers

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2

Shaun D. Wong, Martin Srnec, Megan L. Matthews, Lei V. Liu, Yeonju Kwak, Kiyoung Park, Caleb B. Bell, E. Ercan Alp, Jiyong Zhao, Yoshitaka Yoda, Shinji Kitao, Makoto Seto, Carsten Krebs, Joseph M. Bollinger, Jr., Edward I. Solomon, 2013, Nature on p. 320-323

Evidence for only oxygenative cleavage of aldehydes to alk(a/e)nes and formate by cyanobacterial aldehyde decarbonylases

Ning Li, Wei Chen Chang, Douglas Warui, Squire J. Booker, Carsten Krebs, Joseph M. Bollinger, Jr., 2012, Biochemistry on p. 7908-7916

Detection of formate, rather than carbon monoxide, as the stoichiometric coproduct in conversion of fatty aldehydes to alkanes by a cyanobacterial aldehyde decarbonylase

Douglas M. Warui, Ning Li, Hanne Nørgaard, Carsten Krebs, J. Martin Bollinger, Squire J. Booker, 2011, Journal of the American Chemical Society on p. 3316-3319

Conversion of fatty aldehydes to alka(e)nes and formate by a cyanobacterial aldehyde decarbonylase: Cryptic redox by an unusual dimetal oxygenase

Ning Li, Hanne Nørgaard, Douglas M. Warui, Squire J. Booker, Carsten Krebs, J. Martin Bollinger, 2011, Journal of the American Chemical Society on p. 6158-6161

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

Franklin D. Fuller, Sheraz Gul, Ruchira Chatterjee, E. Sethe Burgie, Iris D. Young, Hugo Lebrette, Vivek Srinivas, Aaron S. Brewster, Tara Michels-Clark, Jonathan A. Clinger, Babak Andi, Mohamed Ibrahim, Ernest Pastor, Casper De Lichtenberg, Rana Hussein, Christopher J. Pollock, Miao Zhang, Claudiu A. Stan, Thomas Kroll, Thomas Fransson, Clemens Weninger, Markus Kubin, Pierre Aller, Louise Lassalle, Philipp Bräuer, Mitchell D. Miller, Muhamed Amin, Sergey Koroidov, Christian G. Roessler, Marc Allaire, Raymond G. Sierra, Peter T. Docker, James M. Glownia, Silke Nelson, Jason E. Koglin, Diling Zhu, Matthieu Chollet, Sanghoon Song, Henrik Lemke, Mengning Liang, Dimosthenis Sokaras, Roberto Alonso-Mori, Athina Zouni, Johannes Messinger, Uwe Bergmann, Amie K. Boal, J. Martin Bollinger, Carsten Krebs, Martin Högbom, George N. Phillips, Richard D. Vierstra, Nicholas K. Sauter, Allen M. Orville, Jan Kern, Vittal K. Yachandra, Junko Yano, 2017, Nature Methods on p. 443-449

Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase

Megan L. Matthews, Wei Chen Chang, Andrew P. Layne, Linde A. Miles, Carsten Krebs, J. Martin Bollinger, 2014, Nature Chemical Biology on p. 209-215

Electronic structure analysis of the oxygen-activation mechanism by Fe <sup>II</sup>- and α-ketoglutarate (αKG)-dependent dioxygenases

Shengfa Ye, Christoph Riplinger, Andreas Hansen, Carsten Krebs, J. Martin Bollinger, Frank Neese, 2012, Chemistry - A European Journal on p. 6555-6567

Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics

Wei Chen Chang, Yisong Guo, Chen Wang, Susan E. Butch, Amy C. Rosenzweig, Amie K. Boal, Carsten Krebs, J. Martin Bollinger, 2014, Science on p. 1140-1144

Evidence for a high-Spin Fe(IV) species in the catalytic cycle of a bacterial phenylalanine hydroxylase

Aram Joel Panay, Michael Lee, Carsten Krebs, Joseph M. Bollinger, Jr., Paul F. Fitzpatrick, 2011, Biochemistry on p. 1928-1933

Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase

Esta Tamanaha, Bo Zhang, Yisong Guo, Wei Chen Chang, Eric W. Barr, Gang Xing, Jennifer St Clair, Shengfa Ye, Frank Neese, J. Martin Bollinger, Carsten Krebs, 2016, Journal of the American Chemical Society on p. 8862-8874