Istvan Albert

Research Professor of Bioinformatics

Istvan Albert

Research Summary

Bioinformatics, large scale biological data analysis, microarrays and sequence analysis. Scientific programming, algorithm development. Database-driven web development.

Huck Affiliations

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Publication Tags

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Genes Proteins Genome Vitamin A Gene Expression Lipids Communication Plasmodium Falciparum Colon Small Intestine Viruses Blood Parasites Nucleic Acids Acids Mutation Tempol Microbiota Polymerase Chain Reaction Obesity Citrobacter Rodentium Carbon Nanotubes Metabolism Piperaquine Drainage

Most Recent Publications

Long-read genome assembly and gene model annotations for the rodent malaria parasite Plasmodium yoelii 17XNL

Mitchell J. Godin, Aswathy Sebastian, Istvan Albert, Scott E. Lindner, 2023, Journal of Biological Chemistry

Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation

Sougat Misra, Tai-Jung Lee, Molly Hall, Aswathy Sebastian, John McGuigan, Chang Liao, Imhoi Koo, A Patterson, Randall Rossi, Molly Hall, Istvan Albert, others, K Prabhu, 2023, Redox Biology on p. 102571

The clock gene Per1 may exert diurnal control over hippocampal memory consolidation

Lauren Bellfy, Chad W. Smies, Alicia R. Bernhardt, Kasuni K. Bodinayake, Aswathy Sebastian, Emily M. Stuart, Destiny S. Wright, Chen Yu Lo, Shoko Murakami, Hannah M. Boyd, Megan J. von Abo, Istvan Albert, Janine L. Kwapis, 2023, Neuropsychopharmacology

Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages

J Okombo, S Mok, T Qahash, T Yeo, J Bath, L Orchard, E Owens, Imhoi Koo, Istvan Albert, Manuel Llinás, D Fidock, 2022, PLoS Pathogens on p. e1010926

Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

Scott Lindner, K Swearingen, M Shears, A Sebastian, M Walker, E Vrana, K Hart, A Minns, Istvan Albert, P Sinnis, R Moritz, Stefan H.I. Kappe, Kappe SHI, 2022, Nature Communications on p. 283

Author Correction: Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development (Nature Communications, (2018), 9, 1, (2656), 10.1038/s41467-018-04966-3)

H Painter, Neo Chung, Aswathy Sebastian, Istvan Albert, John Storey, Llin\'as, Manuel, Manuel Llinás, 2022, Nature Communications on p. 1--1

Transcriptional Profiling of the Small Intestine and the Colon Reveals Modulation of Gut Infection with Citrobacter rodentium According to the Vitamin A Status

Zhi Chai, Yafei Lyu, Qiuyan Chen, Cheng Hsin Wei, I.M. Snyder, Lindsay M. Snyder, Veronika Weaver, Aswathy Sebastian, István Albert, Qunhua Li, Margherita T. Cantorna, Catharine Ross, A Ross, 2022, Nutrients on p. 1563

Advantageous microbial community development and improved performance of pilot-scale field systems treating high-risk acid mine drainage with crab shell

Yishan Lin, Jessica A. Grembi, Sara S. Goots, Aswathy Sebastian, István Albert, Rachel A. Brennan, 2021, Journal of Hazardous Materials

Genomic and Phenotypic Characterization of Chloracidobacterium Isolates Provides Evidence for Multiple Species

Mohit Kumar Saini, Aswathy Sebastian, Yoshiki Shirotori, Nathan T. Soulier, Amaya M. Garcia Costas, Daniela I. Drautz-Moses, Stephan C. Schuster, Istvan Albert, Shin Haruta, Satoshi Hanada, Vera Thiel, Marcus Tank, Donald A. Bryant, 2021, Frontiers in Microbiology

RNAseq studies reveal distinct transcriptional response to vitamin A deficiency in small intestine versus colon, uncovering novel vitamin A-regulated genes

Zhi Chai, Yafei Lyu, Qiuyan Chen, Cheng Hsin Wei, Lindsay M. Snyder, Veronika Weaver, Aswathy Sebastian, István Albert, Qunhua Li, Margherita T. Cantorna, A. Catharine Ross, 2021, Nutrition Reports International

Most-Cited Papers

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

Fei Li, Changtao Jiang, Kristopher W. Krausz, Yunfei Li, Istvan Albert, Haiping Hao, Kristin M. Fabre, James B. Mitchell, Andrew D. Patterson, Frank J. Gonzalez, 2013, Nature Communications

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Changtao Jiang, Cen Xie, Fei Li, Limin Zhang, Robert G. Nichols, Kristopher W. Krausz, Jingwei Cai, Yunpeng Qi, Zhong Ze Fang, Shogo Takahashi, Naoki Tanaka, Dhimant Desai, Shantu G. Amin, Istvan Albert, Andrew D. Patterson, Frank J. Gonzalez, 2015, Journal of Clinical Investigation on p. 386-402

Persistent organic pollutants modify gut microbiota–host metabolic homeostasis in mice through aryl hydrocarbon receptor activation

Limin Zhang, Robert G. Nichols, Jared Correll, Iain A. Murray, Naoki Tanaka, Philip B. Smith, Troy D. Hubbard, Aswathy Sebastian, Istvan Albert, Emmanuel Hatzakis, Frank J. Gonzalez, Gary H. Perdew, Andrew D. Patterson, 2015, Environmental Health Perspectives on p. 679-688

Rapid magnetic isolation of extracellular vesicles via lipid-based nanoprobes

Yuan Wan, Gong Cheng, Xin Liu, Si Jie Hao, Merisa Nisic, Chuan Dong Zhu, Yi Qiu Xia, Wen Qing Li, Zhi Gang Wang, Wen Long Zhang, Shawn J. Rice, Aswathy Sebastian, Istvan Albert, Chandra P. Belani, Si Yang Zheng, 2017, Nature Biomedical Engineering

A rapid and label-free platform for virus capture and identification from clinical samples

Yin Ting Yeh, Kristen Gulino, Yu He Zhang, YuHe Zhanga, Aswathy Sabestien, Tsui-Wen Chou, Bin Zhou, Zhong Lin, Istvan Albert, Huaguang Lu, Venkataraman Swaminathan, Elodie Ghedin, Mauricio Terrones Maldonado, 2020, Proceedings of the National Academy of Sciences of the United States of America on p. 895-901

Gene expression during zombie ant biting behavior reflects the complexity underlying fungal parasitic behavioral manipulation

Charissa de Bekker, Robin A. Ohm, Raquel G. Loreto, Aswathy Sebastian, Istvan Albert, Martha Merrow, Andreas Brachmann, David P. Hughes, 2015, BMC Genomics

Tunable and label-free virus enrichment for ultrasensitive virus detection using carbon nanotube arrays

Yin Ting Yeh, Yi Tang, Aswathy Sebastian, Archi Dasgupta, Nestor Perea-Lopez, Istvan Albert, Huaguang Lu, Mauricio Terrones, Si Yang Zheng, 2016, Science advances on p. e1601026

NusA-dependent transcription termination prevents misregulation of global gene expression

Smarajit Mondal, Alexander V. Yakhnin, Aswathy Sebastian, Istvan Albert, Paul Babitzke, 2016, Nature Microbiology

Testing the kinship theory of intragenomic conflict in honey bees (Apis mellifera)

David A. Galbraith, Sarah D. Kocher, Tom Glenn, Istvan Albert, Greg J. Hunt, Joan E. Strassmann, David C. Queller, Christina M. Grozinger, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 1020-1025

Molecular tandem repeat strategy for elucidating mechanical properties of high-strength proteins

Huihun Jung, Abdon Pena-Francesch, Alham Saadat, Aswathy Sebastian, Dong Hwan Kim, Reginald F. Hamilton, Istvan Albert, Benjamin D. Allen, Melik C. Demirel, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 6478-83