Isabella Cattadori

Associate Professor of Biology

W128 Millennium Science Complex
University Park, PA 16802
imc3@psu.edu
814-865-9594

Research Summary

Immuno-epidemiology of co-infection, how host immunity modulates parasite interactions and transmission and how host molecular processes explain the dynamics of infection at the population level.

Huck Affiliations

Center for Infectious Disease Dynamics

Ecology

Molecular, Cellular, and Integrative Biosciences

Ecology Institute

Publication Tags

Infection Rabbits Parasites Helminths Immune Response Myxoma Virus Infections Bacteria Genome Genes Virulence Microbiota Tanzania Parasite Coinfection Bioinformatics Visualization Mixed Infection Viruses Climate Change Temperature Seasonal Variation Phenotype History Pipelines

Most Recent Papers

Identification of Bacillus anthracis, Brucella spp., and Coxiella burnetii DNA signatures from bushmeat

Robab Katani, Megan A. Schilling, Beatus Lyimo, Ernest Eblate, Andimile Martin, Triza Tonui, Isabella M. Cattadori, Stephen C. Francesconi, Anna Bond Estes, Dennis Rentsch, Sreenidhi Srinivasan, Samson Lyimo, Lidia Munuo, Christian K. Tiambo, Francesca Stomeo, Paul Gwakisa, Fausta Mosha, Peter John Hudson, Joram J. Buza, Vivek Kapur, 2021, Scientific Reports

Gastrointestinal Helminths Increase Bordetella bronchiseptica Shedding and Host Variation in Supershedding

Nhat Nguyen, A Pathak, Isabella Cattadori, 2021, bioRxiv

The Enemy of my Enemy is my Friend: Immune-Mediated Facilitation Contributes to Fitness of Co-Infecting Helminths

Francesca Dagostin, Chiara Vanalli, Brian Boag, Renato Casagrandi, Marino Gatto, Lorenzo Mari, Isabella Cattadori, 2021, bioRxiv

Within-host mechanisms of immune regulation explain the contrasting dynamics of two helminth species in both single and dual infections

Chiara Vanalli, Lorenzo Mari, Lorenzo Righetto, Renato Casagrandi, Marino Gatto, Isabella M. Cattadori, 2020, PLoS Computational Biology

Identifying age cohorts responsible for peste des petits ruminants virus transmission among sheep, goats, and cattle in northern Tanzania

C. Herzog, W. de Glanville, B. Willett, I. M. Cattadori, V. Kapur, Peter Hudson, J. Buza, E. Swai, S. Cleaveland, O. N. Bjørnstad, O Bjornstad, 2020, Viruses

Microbial Diversity in Bushmeat Samples Recovered from the Serengeti Ecosystem in Tanzania

Robab Katani, Megan Schilling, Beatus Lyimo, Triza Tonui, Isabella Cattadori, Ernest Eblate, Andimile Martin, Anna Estes, Teresia Buza, Dennis Rentsch, Karen Davenport, Blake Hovde, Samson Lyimo, Lydia Munuo, Francesca Stomeo, Christian Tiambo, Jessica Radzio-Basu, Fausta Mosha, P Hudson, Joram Buza, V Kapur, 2019, Scientific Reports

External disturbances impact helminth–host interactions by affecting dynamics of infection, parasite traits, and host immune responses

Isabella M. Cattadori, Ashutosh K. Pathak, Matthew J. Ferrari, 2019, Ecology and Evolution on p. 13495-13505

IMAP: An integrated bioinformatics and visualization pipeline for microbiome data analysis

Teresia M. Buza, Triza Tonui, Francesca Stomeo, Christian Tiambo, Robab Katani, Megan Schilling, Beatus Lyimo, Paul Gwakisa, Isabella M. Cattadori, Joram Buza, Vivek Kapur, 2019, BMC Bioinformatics

Innate Immune Genes Associated With Newcastle Disease Virus Load in Chick Embryos From Inbred and Outbred Lines.

M Schilling, S Memari, Isabella Cattadori, R Katani, A Muhairwa, J Buza, V Kapur, 2019, Frontiers in Microbiology on p. 1432

Processes generating heterogeneities in infection and transmission in a parasite-rabbit system

Isabella M. Cattadori, Ashutosh Pathak, Brian Boag, 2019, Wildlife Disease Ecology: Linking Theory to Data and Application on p. 598-622

Most-Cited Papers

Evolutionary history and attenuation of myxoma virus on two continents.

P Kerr, E Ghedin, J DePasse, A Fitch, Isabella Cattadori, P Hudson, D Tscharke, A Read, E Holmes, 2012, PLoS Pathogens on p. e1002950

Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype

Peter J. Kerr, Isabella M. Cattadori, June Liu, Derek G. Sim, Jeff W. Dodds, Jason W. Brooks, Mary J. Kennett, Edward C. Holmes, Andrew F. Read, 2017, Proceedings of the National Academy of Sciences of the United States of America on p. 9397-9402

Impact of helminth infections and nutritional constraints on the small intestine microbiota

Isabella M. Cattadori, Aswathy Sebastian, Han Hao, Robab Katani, Istvan Albert, Kirsten E. Eilertson, Vivek Kapur, Ashutosh Pathak, Susan Mitchell, 2016, PLoS One on p. e0159770

Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth

Juilee Thakar, Ashutosh K. Pathak, Lisa Murphy, Réka Albert, Isabella M. Cattadori, 2012, PLoS Computational Biology

Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread

Peter J. Kerr, Matthew B. Rogers, Adam Fitch, Jay V. DePasse, Isabella M. Cattadori, Alan C. Twaddle, Peter J. Hudson, David C. Tscharke, Andrew F. Read, Edward C. Holmes, Elodie Ghedin, 2013, Journal of Virology on p. 12900-12915

Immuno-epidemiology of chronic bacterial and helminth co-infections: Observations from the field and evidence from the laboratory

Ashutosh K. Pathak, Chad Pelensky, Brian Boag, Isabella M. Cattadori, 2012, International Journal for Parasitology on p. 647-655

A co-infection with two gastrointestinal nematodes alters host immune responses and only partially parasite dynamics

L. Murphy, A. K. Pathak, I. M. Cattadori, 2013, Parasite Immunology on p. 421-432

Climate changes influence free-living stages of soil-transmitted parasites of European rabbits

Alexander D. Hernandez, Adam Poole, Isabella M. Cattadori, 2013, Global Change Biology on p. 1028-1042

Seasonal variation of tsetse fly species abundance and prevalence of trypanosomes in the Maasai Steppe, Tanzania.

H Nnko, A Ngonyoka, L Salekwa, A Estes, P Hudson, P Gwakisa, Isabella Cattadori, 2017, Journal of Vector Ecology on p. 24-33

Comparative analysis of the complete genome sequence of the california msw strain of myxoma virus reveals potential host adaptations

Peter J. Kerr, Matthew B. Rogers, Adam Fitch, Jay V. DePasse, Isabella M. Cattadori, Peter J. Hudson, David C. Tscharke, Edward C. Holmes, Elodie Ghedin, 2013, Journal of Virology on p. 12080-12089

News Articles Featuring Isabella Cattadori

Jan 10, 2022

‘Flurona’ is real, but don’t panic — it’s common to get two viruses at once

No, flurona is not some scary new variant of the coronavirus. And — do we really need to say this? — it is not an actual scientific term. But the phenomenon of “coinfection” with influenza and the coronavirus is real and, to those in the medical community, not the least bit surprising. A person can be infected with multiple viruses at the same time — or with a virus and some other type of pathogen, such as bacteria or parasites.

Full Article

Apr 06, 2020

Efforts to control livestock disease should focus on management style, not age

The risk of transmitting the virus PPRV, which produces a highly infectious and often fatal disease in sheep and goats, does not appear to vary significantly by an animal’s age, unlike its sibling virus measles, which is most prominent in children.