Ibrahim Ozbolat

Huck Chair in 3D Bioprinting and Regenerative Medicine, Professor of Engineering Science and Mechanics

Ibrahim Ozbolat

Huck Affiliations

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Most Recent Publications

Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration

I. Deniz Derman, Taino Rivera, Laura Garriga Cerda, Yogendra Pratap Singh, Shweta Saini, Hasan Erbil Abaci, Ibrahim T. Ozbolat, 2025, International Journal of Extreme Manufacturing

Multi-Functional Gelatin-Dithiolane Hydrogels for Tissue Engineering

Saad Asim, Cody Tuftee, Asma Talib Qureshi, Rachel Callaghan, Moira L. Geary, Mithun Santra, Vaibhav Pal, Ilayda Namli, Gary Hin Fai Yam, Ibrahim T. Ozbolat, Muhammad Rizwan, 2025, Advanced Functional Materials

Understanding the cellular dynamics, engineering perspectives and translation prospects in bioprinting epithelial tissues

Irem Deniz Derman, Joseph Christakiran Moses, Taino Rivera, Ibrahim T. Ozbolat, 2025, Bioactive Materials on p. 195-224

Progress in Organ Bioprinting for Regenerative Medicine

Xiang Wang, Di Zhang, Yogendra Pratap Singh, Miji Yeo, Guotao Deng, Jiaqi Lai, Fei Chen, Ibrahim T. Ozbolat, Yin Yu, 2024, Engineering on p. 121-142

A narrative review: 3D bioprinting of cultured muscle meat and seafood products and its potential for the food industry

Mediha Gurel, Nikheel Rathod, Laura Y. Cabrera, Stephen Voyton, Miji Yeo, Fatih Ozogul, Ibrahim Tarik Ozbolat, 2024, Trends in Food Science and Technology

Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix induces hair follicle-like downgrowths and adipose tissue formation during full-thickness craniomaxillofacial skin reconstruction

Youngnam Kang, Miji Yeo, Irem Deniz Derman, Dino J. Ravnic, Yogendra Pratap Singh, Mecit Altan Alioglu, Yang Wu, Jasson Makkar, Ryan R. Driskell, Ibrahim T. Ozbolat, 2024, Bioactive Materials on p. 114-128

A Versatile Photocrosslinkable Silicone Composite for 3D Printing Applications

Mecit Altan Alioglu, Yasar Ozer Yilmaz, Ethan Michael Gerhard, Vaibhav Pal, Deepak Gupta, Syed Hasan Askari Rizvi, Ibrahim T. Ozbolat, 2024, Advanced Materials Technologies

Synergistic coupling between 3D bioprinting and vascularization strategies

Miji Yeo, Anwita Sarkar, Yogendra Pratap Singh, Irem Deniz Derman, Pallab Datta, Ibrahim T. Ozbolat, 2024, Biofabrication

High-throughput bioprinting of spheroids for scalable tissue fabrication

Myoung Hwan Kim, Yogendra Pratap Singh, Nazmiye Celik, Miji Yeo, Elias Rizk, Daniel J. Hayes, Ibrahim Tarik Ozbolat, 2024, Nature Communications on p. 10083

A comprehensive review on 3D tissue models: Biofabrication technologies and preclinical applications

Renjian Xie, Vaibhav Pal, Yanrong Yu, Xiaolu Lu, Mengwei Gao, Shijie Liang, Miao Huang, Weijie Peng, Ibrahim T. Ozbolat, 2024, Biomaterials

Most-Cited Papers

Current advances and future perspectives in extrusion-based bioprinting

Ibrahim T. Ozbolat, Monika Hospodiuk, 2016, Biomaterials on p. 321-343

The bioink: A comprehensive review on bioprintable materials

Monika Hospodiuk, Madhuri Dey, Donna Sosnoski, Ibrahim T. Ozbolat, 2017, Biotechnology Advances on p. 217-239

A comprehensive review on droplet-based bioprinting: Past, present and future

Hemanth Gudapati, Madhuri Dey, Ibrahim Ozbolat, 2016, Biomaterials on p. 20-42

Bioprinting for vascular and vascularized tissue biofabrication

Pallab Datta, Bugra Ayan, Ibrahim T. Ozbolat, 2017, Acta Biomaterialia on p. 1-20

The bioprinting roadmap

Wei Sun, Binil Starly, Andrew C. Daly, Jason A. Burdick, Jürgen Groll, Gregor Skeldon, Wenmiao Shu, Yasuyuki Sakai, Marie Shinohara, Masaki Nishikawa, Jinah Jang, Dong Woo Cho, Minghao Nie, Shoji Takeuchi, Serge Ostrovidov, Ali Khademhosseini, Roger D. Kamm, Vladimir Mironov, Lorenzo Moroni, Ibrahim T. Ozbolat, 2020, Biofabrication

Bioprinting scale-up tissue and organ constructs for transplantation

Ibrahim T. Ozbolat, 2015, Trends in Biotechnology on p. 395-400

Application areas of 3D bioprinting

Ibrahim T. Ozbolat, Weijie Peng, Veli Ozbolat, 2016, Drug Discovery Today on p. 1257-1271

3D bioprinting for drug discovery and development in pharmaceutics

Weijie Peng, Pallab Datta, Bugra Ayan, Veli Ozbolat, Donna Sosnoski, Ibrahim T. Ozbolat, 2017, Acta Biomaterialia on p. 26-46

Three-dimensional bioprinting using self-Assembling scalable scaffold-free "tissue strands" as a new bioink

Yin Yu, Kazim K. Moncal, Jianqiang Li, Weijie Peng, Iris Rivero, James A. Martin, Ibrahim T. Ozbolat, 2016, Scientific Reports

3D bioprinting for reconstituting the cancer microenvironment

Pallab Datta, Madhuri Dey, Zaman Ataie, Derya Unutmaz, Ibrahim T. Ozbolat, 2020, npj Precision Oncology

News Articles Featuring Ibrahim Ozbolat

Feb 28, 2025

Could 3D-printed air revolutionize bioprinting?

A novel technique for creating voids and channels within bioprinted living tissues could help break the vascularization barrier, unlocking the next generation of medical applications for the technology.

Full Article

Dec 03, 2024

New bioprinting technique creates functional tissue 10x faster

The novel high-throughput-bioprinting technique opens the door for tissue fabrication with high cell density at scale.

Full Article

Mar 27, 2024

Synthetic material could improve ease and cut cost of gut microbiome research

A team of Penn State researchers has developed a new synthetic material that could enable scientists to more easily study how microorganisms interact with the gastrointestinal (GI) system.

Full Article

Mar 08, 2024

3D-printed skin could heal wounds with less scarring

Scientists have directly 3D-printed skin to heal open wounds — an achievement that could one day lead to less scarring following reconstructive surgery

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Mar 07, 2024

Scientists 3D Print Living Human Skin Directly Onto Wounds

Scientists have 3D printed living human skin tissue onto open wounds on rats

Full Article

Mar 05, 2024

In a first, scientists 3D bioprint skin during live operation in rats

Researchers have successfully used 3D bioprinting to add layer of skin during an operation to aid recovery

Full Article

Mar 01, 2024

3D-printed skin closes wounds and contains hair follicle precursors

Fat tissue holds the key to 3D printing layered living skin and potentially hair follicles, according to researchers who recently harnessed fat cells and supporting structures from clinically procured human tissue to precisely correct injuries in rats.

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Aug 30, 2023

3D Printing Industry News Sliced: Element Materials, Farsoon, Mechnano, enable 3D, Renishaw, and more

The latest news on 3D printing that give modern makeovers

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Aug 29, 2023

5 questions with a researcher: “Printing replacement organs is the ultimate goal”

Dr. Ibrahim Ozbolat talks about is team specializing in 3D printing human tissue and bone

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Jul 20, 2023

NIH grant to facilitate high-speed bioprinting of bones, tracheas, organs

Developing technology to quickly and efficiently bioprint human tissues at scale is the goal of a new project led by Penn State researchers. When fully developed, the technology will be the first to enable the fabrication of scalable, native tissues such as bones, tracheas and organs.

Full Article

Mar 17, 2023

This insertable 3D printer will repair tissue damage from the inside

It can also make incisions and clean up with water jets.

Full Article

Oct 19, 2022

Penn State researchers 3D bioprint breast cancer tumours and treat them in new 'groundbreaking' study

Researchers at Pennsylvania State University have successfully 3D bioprinted breast cancer tumours and treated them in a new study to better understand the disease that is one of the biggest killers worldwide.

Full Article

Oct 18, 2022

Researchers 3D bioprint breast cancer tumors, treat them in groundbreaking study

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

Full Article

Jul 08, 2021

Penn State research teams awarded seed grants to advance biodevices

Interdisciplinary research teams from across Penn State recently received seed grants from the Penn State Biodevices Seed Grant program and the Grace Woodward Collaborative Research in Engineering and Medicine Grant program to fund their work in advancing biodevices.

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May 03, 2021

The micro-environment of breast cancer in three dimensions

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue of their host. They alter the genetics of surrounding cells and evolve to avoid the protective attacks of immune cells. Now, Penn State researchers have developed a way to study the relationship between solid, difficult-to-treat tumors and the microenvironment they create to support their growth.

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Apr 27, 2021

Novel bioprinting procedure may enhance craniofacial skin and bone repair

Researchers at Penn State University have successfully repaired craniofacial skin and bone by implementing bioprinting technology during surgery.

Full Article

Oct 16, 2020

Gel instrumental in 3D bioprinting biological tissues

The eventual creation of replacement biological parts requires fully three-dimensional capabilities that two-dimensional and three-dimensional thin-film bioprinting cannot supply. Now, using a yield stress gel, Penn State engineers can place tiny aggregates of cells exactly where they want to build the complex shapes that will be necessary to replace bone, cartilage and other tissues.

Full Article

Mar 06, 2020

Machine sucks up tiny tissue spheroids and prints them precisely

A new method of bioprinting uses aspiration of tiny biologics such as spheroids, cells and tissue strands, to precisely place them in 3D patterns either on scaffolding or without to create artificial tissues with natural properties, according to Penn State researchers.

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Feb 07, 2020

$2.8M grant to fund bioprinting for reconstruction of face, mouth, skull tissues

Seamlessly correcting defects in the face, mouth and skull is highly challenging because it requires precise stacking of a variety of tissues including bone, muscle, fat and skin. Now, Penn State researchers are investigating methods to 3D bioprint and grow the appropriate tissues for craniomaxillofacial reconstruction.

Full Article