Hyunwook Lee
Postdoctoral Researcher
Huck Affiliations
Publication Tags
These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.
Capsid Viruses Enterovirus Epitopes Proteins Antibodies Cryoelectron Microscopy Neutralizing Antibodies Cryo Electron Microscopy Canine Parvovirus Human Papillomavirus 16 Receptors Carnivore Protoparvovirus 1 Immunoglobulin Fragments Picornaviridae Genome Capsid Proteins Monoclonal Antibodies Microvirus Ribonucleoproteins Virion Ribonucleases Asoxime Chloride Coat Proteins DogsMost Recent Publications
Cryo-EM Structure of Gokushovirus UEC6098 Reveals a Novel Capsid Architecture for a Single-Scaffolding Protein, Microvirus Assembly System
Hyunwook Lee, Alexis J. Baxter, Carol M. Bator, Bentley A. Fane, Susan L. Hafenstein, 2022, Journal of Virology
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
Anna Perederina, Di Li, Hyunwook Lee, Carol Bator, Igor Berezin, Susan L. Hafenstein, Andrey S. Krasilnikov, 2020, Nature Communications
Limited intrahost diversity and background evolution accompany 40 years of canine parvovirus host adaptation and spread
Ian E.H. Voorhees, Hyunwook Lee, Andrew B. Allison, Robert Lopez-Astacio, Laura B. Goodman, Oyebola O. Oyesola, Olutayo Omobowale, Olusegun Fagbohun, Edward J. Dubovi, Susan L. Hafenstein, Edward C. Holmes, Colin R. Parrish, 2020, Journal of Virology
A SCAFFOLD SIMPLIFICATION STRATEGY LEADS TO A NOVEL GENERATION OF DUAL HUMAN IMMUNODEFICIENCY VIRUS AND ENTEROVIRUS-A71 ENTRY INHIBITORS
Belén Martínez-Gualda, Liang Sun, Olaia Martí-Marí, Sam Noppen, Rana Abdelnabi, Carol Bator, Ernesto Quesada, Leen Delang, Carmen Mirabelli, Hyunwook Lee, Dominique Schols, Johan Neyts, S Hafenstein, María-José Camarasa, Federico Gago, Ana San-Felix, 2019, Journal of Medicinal Chemistry on p. acs.jmedchem.9b01737
Transferrin receptor binds virus capsid with dynamic motion
Hyunwook Lee, Heather M. Callaway, Javier O. Cifuente, Carol M. Bator, Colin R. Parrish, Susan L. Hafenstein, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 20462-20471
Limited intra-host diversity and background evolution accompany 40 years of canine parvovirus host adaptation and spread
Ian Voorhees, Hyunwook Lee, Andrew Allison, Robert Lopez-Astacio, Laura Goodman, Oyebola Oyesola, Olutayo Omobowale, Olusegun Fagbohun, Edward Dubovi, S Hafenstein, Edward Holmes, Colin Parrish, 2019, Journal of Virology on p. JVI.01162--19, jvi;JVI.01162--19v1
Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus - A 71 capsid
Liang Sun, Hyunwook Lee, Hendrik Jan Thibaut, Kristina Lanko, Eva Rivero-Buceta, Carol Bator, Belen Martinez-Gualda, Kai Dallmeier, Leen Delang, Pieter Leyssen, Federico Gago, Ana San-Felix, Susan Hafenstein, Carmen Mirabelli, Johan Neyts, 2019, PLoS Pathogens
CryoEM reconstruction approaches to resolve asymmetric features
Daniel Goetschius, Hyunwook Lee, Susan Hafenstein, 2019, Advances in virus research on p. 73--91
Activated protein c attenuates severe inflammation by targeting VLA-3high neutrophil subpopulation in mice
Pranita P. Sarangi, Hyun Wook Lee, Yelena V. Lerman, Alissa Trzeciak, Eric J. Harrower, Alireza R. Rezaie, Minsoo Kim, 2017, Journal of Immunology on p. 2930-2936
MOPS and coxsackievirus B3 stability
Steven D. Carson, Susan Hafenstein, Hyunwook Lee, 2017, Virology on p. 183-187
Most-Cited Papers
Enterovirus 71 Binding to PSGL-1 on Leukocytes: VP1-145 Acts as a Molecular Switch to Control Receptor Interaction
Yorihiro Nishimura, Hyunwook Lee, Susan Hafenstein, Chikako Kataoka, Takaji Wakita, Jeffrey M. Bergelson, Hiroyuki Shimizu, 2013, PLoS Pathogens on p. e1003511
Optogenetic control of chemokine receptor signal and T-cell migration
Yuexin Xu, Young Min Hyun, Kihong Lim, Hyunwook Lee, Ryan J. Cummings, Scott A. Gerber, Seyeon Bae, Thomas Yoonsang Cho, Edith M. Lord, Minsoo Kim, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 6371-6376
A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment
Hyunwook Lee, Sarah A. Brendle, Stephanie M. Bywaters, Jian Guan, Robert E. Ashley, Joshua D. Yoder, Alexander M. Makhov, James F. Conway, Neil D. Christensen, Susan Hafenstein, 2015, Journal of Virology on p. 1428-1438
A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody
Hyunwook Lee, Javier O. Cifuente, Robert E. Ashley, James F. Conway, Alexander M. Makhov, Yoshio Tano, Hiroyuki Shimizu, Yorihiro Nishimura, Susan Hafenstein, 2013, Journal of Virology on p. 11363-11370
Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization
Jian Guan, Stephanie M. Bywaters, Sarah A. Brendle, Hyunwook Lee, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Neil Christensen, Susan Hafenstein, 2015, Virology on p. 253-263
The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs
Hyunwook Lee, Kristin L. Shingler, Lindsey J. Organtini, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Susan Hafenstein, 2016, Science advances
Limited intrahost diversity and background evolution accompany 40 years of canine parvovirus host adaptation and spread
Ian E.H. Voorhees, Hyunwook Lee, Andrew B. Allison, Robert Lopez-Astacio, Laura B. Goodman, Oyebola O. Oyesola, Olutayo Omobowale, Olusegun Fagbohun, Edward J. Dubovi, Susan L. Hafenstein, Edward C. Holmes, Colin R. Parrish, 2020, Journal of Virology
Structures of the procapsid and mature virion of enterovirus 71 strain 1095
Javier O. Cifuente, Hyunwook Lee, Joshua D. Yoder, Kristin L. Shingler, Michael S. Carnegie, Jennifer L. Yoder, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Susan Hafenstein, 2013, Journal of Virology on p. 7637-7645
The U4 antibody epitope on human papillomavirus 16 identified by cryo-electron microscopy
Jian Guan, Stephanie M. Bywaters, Sarah A. Brendle, Hyunwook Lee, Robert E. Ashley, Neil D. Christensen, Susan Hafenstein, 2015, Journal of Virology on p. 12108-12117
Near-atomic resolution structure of a highly neutralizing fab bound to canine parvovirus
Lindsey J. Organtini, Hyunwook Lee, Sho Iketani, Kai Huang, Robert E. Ashley, Alexander M. Makhov, James F. Conway, Colin R. Parrish, Susan Hafenstein, 2016, Journal of Virology on p. 9733-9742