Hong-Gang Wang
Professor of Pharmacology
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Hershey Med Ctr
Hershey, - huw11@psu.edu
Publication Tags
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Neoplasms Neuroblastoma Autophagy Membranes Ion Channels Apoptosis Tumors Endosomal Sorting Complexes Required For Transport Proteins Therapeutics Autophagosomes Cell Survival Necrosis Hypoxia Inducible Factor 1 Sphingolipids Acute Myeloid Leukemia Neutrophils Beclin 1 Cell Death Cell Viability Cells Doxorubicin Growth Leukemia Transient Receptor Potential ChannelsMost Recent Publications
The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression
Lei Bao, Fernanda Festa, Iwona Hirschler-Laszkiewicz, Kerry Keefer, Hong Gang Wang, Joseph Y. Cheung, Barbara A. Miller, 2022, Scientific Reports
The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1
Iwona Hirschler-Laszkiewicz, Fernanda Festa, Suming Huang, George Lucian Moldovan, Claudia Nicolae, Ashna Dhoonmoon, Lei Bao, Kerry Keefer, Shu jen Chen, Hong Gang Wang, Joseph Y. Cheung, Barbara A. Miller, 2022, Scientific Reports
Distinct noncoding RNAs and RNA binding proteins associated with high-risk pediatric and adult acute myeloid leukemias detected by regulatory network analysis
Zhenqiu Liu, Vladimir S. Spiegelman, Hong Gang Wang, 2022, Cancer Reports
Small extracellular vesicles induce resistance to anti-GD2 immunotherapy unveiling tipifarnib as an adjunct to neuroblastoma immunotherapy
Xiaoming Liu, Carson A. Wills, Longgui Chen, Jiawen Zhang, Yuanjun Zhao, Mi Zhou, Jeffrey Sundstrom, Todd Schell, Vladimir S. Spiegelman, Megan M. Young, Hong Gang Wang, 2022, Journal for ImmunoTherapy of Cancer
Thoracic Neuroblastoma: A Novel Surgical Model for the Study of Extra-adrenal Neuroblastoma
Christa N. Grant, Carson A. Wills, Xiaoming Liu, Vladimir S. Spiegelman, Hong Gang Wang, 2022, In Vivo on p. 49-56
Robust and Efficient Assessment of Potency (REAP) as a quantitative tool for dose-response curve estimation
Shouhao Zhou, Xinyi Liu, Xinying Fang, Vernon M. Chinchilli, Michael Wang, Hong Gang Wang, Nikolay V. Dokholyan, Chan Shen, J Lee, 2022, eLife on p. e78634
PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression
Emmanuel K. Teye, Shasha Lu, Fangyuan Chen, Wenrui Yang, Thomas Abraham, Douglas B. Stairs, Hong Gang Wang, Gregory S. Yochum, Robert A. Brodsky, Jeffrey J. Pu, 2021, Scientific Reports
NMR resonance assignments of human Atg3 in aqueous solution and bicelles
Yansheng Ye, Guifang Wang, Maria C. Bewley, Hong-Gang Wang, Fang Tian, 2021, Biomolecular NMR Assignments on p. 421-425
Data-driven math model of FLT3-ITD acute myeloid leukemia reveals potential therapeutic targets
David J. Wooten, Melat Gebru, Hong Gang Wang, Réka Albert, 2021, Journal of Personalized Medicine
Targeting the ESCRT-III component CHMP2A for noncanonical Caspase-8 activation on autophagosomal membranes
Tatsuya Hattori, Yoshinori Takahashi, Longgui Chen, Zhenyuan Tang, Carson A. Wills, Xinwen Liang, Hong Gang Wang, 2021, Cell Death and Differentiation on p. 657-670
Most-Cited Papers
Sphingolipids: Regulators of crosstalk between apoptosis and autophagy
Megan M. Young, Mark Kester, Hong Gang Wang, 2013, Journal of Lipid Research on p. 5-19
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
Yoshinori Takahashi, Haiyan He, Zhenyuan Tang, Tatsuya Hattori, Ying Liu, Megan M. Young, Jacob M. Serfass, Longgui Chen, Melat Gebru, Chong Chen, Carson A. Wills, Jennifer M. Atkinson, Han Chen, Thomas Abraham, Hong Gang Wang, 2018, Nature Communications
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
Patricia P. Yee, Yiju Wei, Soo Yeon Kim, Tong Lu, Stephen Y. Chih, Cynthia Lawson, Miaolu Tang, Zhijun Liu, Benjamin Anderson, Krishnamoorthy Thamburaj, Megan M. Young, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Charles S. Specht, Hong Gang Wang, Wei Li, 2020, Nature Communications
Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy
Yonghua Yang, Warren Fiskus, Bao Yong, Peter Atadja, Yoshinori Takahashi, Tej K. Pandita, Hong Gang Wang, Kapil N. Bhalla, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 6841-6846
Mechanisms and context underlying the role of autophagy in cancer metastasis
Christopher M. Dower, Carson A. Wills, Steven M. Frisch, Hong Gang Wang, 2018, Autophagy on p. 1110-1128
A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α
Shu Jen Chen, Nicholas E. Hoffman, Santhanam Shanmughapriy, Lei Bao, Kerry Keefer, Kathleen Conrad, Salim Merali, Yoshinori Takahashi, Thomas Abraham, Iwona Hirschler-Laszkiewicz, Ju Fang Wang, Xue Qian Zhang, Jianliang Song, Carlos Barrero, Yuguang Shi, Yuka Imamura Kawasawa, Michael Bayerl, Tianyu Sun, Mustafa Barbour, Hong Gang Wang, Muniswamy Madesh, Joseph Y. Cheung, Barbara A. Miller, 2014, Journal of Biological Chemistry on p. 36284-36302
Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion
S. Wei, X. Chen, K. McGraw, L. Zhang, R. Komrokji, J. Clark, G. Caceres, D. Billingsley, L. Sokol, J. Lancet, N. Fortenbery, J. Zhou, E. A. Eksioglu, D. Sallman, H. Wang, P. K. Epling-Burnette, J. Djeu, M. Sekeres, J. P. Maciejewski, A. List, 2013, Oncogene on p. 1110-1120
PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex
Shanshan He, Duojiao Ni, Binyun Ma, Joo Hyung Lee, Tian Zhang, Irene Ghozalli, Sara Dolatshahi Pirooz, Zhen Zhao, Nagakumar Bharatham, Baihong Li, Soohwan Oh, Wen Hwa Lee, Yoshinori Takahashi, Hong-Gang Wang, Arlet Minassian, Pinghui Feng, Vojo Deretic, Rainer Pepperkok, Mitsuo Tagaya, Ho Sup Yoon, Chengyu Liang, 2013, Nature Cell Biology on p. 1206-1219