Gustavo Nader

Associate Professor of Kinesiology

Gustavo Nader

Research Summary

Skeletal muscle growth control and adaptations to exercise. Ribosome biogenesis, transcriptional and epigenetic regulation of RNA Polymerase I.

Huck Graduate Students

Huck Affiliations


Publication Tags

Muscles Skeletal Muscle Hypertrophy Proteins Ribosomal Dna Gene Expression Ribosomes Muscle Skeletal Muscle Fibers Muscle Proteins Amp Activated Protein Kinases Sirolimus Chromatin Assembly And Disassembly Exercise Resistance Training Genes Interleukin 15 Immunosuppressive Agents Microarray Analysis Therapeutics Carbon Monoxide Interleukin 15 Receptor Alpha Subunit Growth Cytokines Extracellular Matrix

Most Recent Papers

Reduced rDNA transcription diminishes skeletal muscle ribosomal capacity and protein synthesis in cancer cachexia

Hyo Gun Kim, Joshua R. Huot, Fabrizio Pin, Bin Guo, Andrea Bonetto, Gustavo A. Nader, 2021, FASEB Journal

Elevated CO<sub>2</sub> regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans

Masahiko Shigemura, Emilia Lecuona, Martín Angulo, Laura A. Dada, Melanie B. Edwards, Lynn C. Welch, S. Marina Casalino-Matsuda, Peter H.S. Sporn, István Vadász, Iiro Taneli Helenius, Gustavo A. Nader, Yosef Gruenbaum, Kfir Sharabi, Eoin Cummins, Cormac Taylor, Ankit Bharat, Cara J. Gottardi, Greg J. Beitel, Naftali Kaminski, G. R.Scott Budinger, Sergejs Berdnikovs, Jacob I. Sznajder, 2019, Scientific Reports

Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and MOTS-C and Nrf2 in chronic kidney disease

Chang Liu, Eva Karin Gidlund, Anna Witasp, Abdul Rashid Qureshi, Magnus Söderberg, Anders Thorell, Gustavo A. Nader, Peter Barany, Peter Stenvinkel, Ferdinand von Walden, 2019, American Journal of Physiology - Renal Physiology on p. F1122-F1131

Regulation of Ribosome Biogenesis during Skeletal Muscle Hypertrophy

Hyo Gun Kim, Bin Guo, Gustavo A. Nader, 2019, Exercise and Sport Sciences Reviews on p. 91-97

The mitochondrial peptides humanin and MOTS-C are differentially regulated in chronic kidney disease: links to mitochondrial dysfunction and oxidative stress

Chang Liu, Gustavo Nader, 2019, Am J Physiol – Renal Physiology

Muscle contractures in patients with cerebral palsy and acquired brain injury are associated with extracellular matrix expansion, pro-inflammatory gene expression, and reduced rRNA synthesis

Ferdinand Von Walden, Stefan Gantelius, Chang Liu, Hanna Borgström, Lars Björk, Ola Gremark, Per Stål, Gustavo A. Nader, Eva PontéN, 2018, Muscle and Nerve on p. 277-285

mTOR signaling regulates myotube hypertrophy by modulating protein synthesis, rDNA transcription, and chromatin remodeling

Ferdinand von Walden, Chang Liu, Nicole Aurigemma, Gustavo A. Nader, 2016, American Journal of Physiology on p. C663-C672

Commentary on viewpoint

Gustavo A. Nader, 2016, Journal of Applied Physiology on p. 599

AMPKγ3 is dispensable for skeletal muscle hypertrophy induced by functional overload

Isabelle Riedl, Megan E. Osler, Marie Björnholm, Brendan Egan, Gustavo Alberto Nader, Alexander V. Chibalin, Juleen R. Zierath, 2016, American Journal of Physiology on p. E461-E472

Most-Cited Papers

Resistance exercise training modulates acute gene expression during human skeletal muscle hypertrophy

G. A. Nader, F. Von Walden, C. Liu, J. Lindvall, L. Gutmann, E. E. Pistilli, P. M. Gordon, 2014, Journal of Applied Physiology on p. 693-702

Muscle wasting in end-stage renal disease promulgates premature death

Peter Stenvinkel, Juan Jesus Carrero, Ferdinand Von Walden, T. Alp Ikizler, Gustavo A. Nader, 2016, Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress on p. 1070-1077

High CO<sub>2</sub> levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific ring finger protein 1 (MuRF1)

Ariel Jaitovich, Martín Angulo, Emilia Lecuona, Laura A. Dada, Lynn C. Welch, Yuan Cheng, Galina Gusarova, Ermelinda Ceco, Chang Liu, Masahiko Shigemura, Esther Barreiro, Cam Patterson, Gustavo A. Nader, Jacob I. Sznajder, 2015, Journal of Biological Chemistry on p. 9183-9194

Mechanical loading induces the expression of a Pol I regulon at the onset of skeletal muscle hypertrophy

Ferdinand von Walden, Vandre Casagrande, Ann Kristin Östlund Farrants, Gustavo A. Nader, 2012, American Journal of Physiology on p. C1523-C1530

Resistance exercise training influences skeletal muscle immune activation

Paul M. Gordon, Dongmei Liu, Maureen A. Sartor, Heidi B. IglayReger, Emidio E. Pistilli, Laurie Gutmann, Gustavo A. Nader, Eric P. Hoffman, 2012, Journal of Applied Physiology on p. 443-453

Anti-inflammatory cytokine profile in early human tendon repair

P. W. Ackermann, E. Domeij-Arverud, P. Leclerc, P. Amoudrouz, Gustavo Alberto Nader, 2013, Knee Surgery, Sports Traumatology, Arthroscopy on p. 1801-1806

mTOR signaling regulates myotube hypertrophy by modulating protein synthesis, rDNA transcription, and chromatin remodeling

Ferdinand von Walden, Chang Liu, Nicole Aurigemma, Gustavo A. Nader, 2016, American Journal of Physiology on p. C663-C672

Microarray analysis reveals novel features of the muscle aging process in men and women

Dongmei Liu, Maureen A. Sartor, Gustavo A. Nader, Emidio E. Pistilli, Leah Tanton, Charles Lilly, Laurie Gutmann, Heidi B. Iglayreger, Paul S. Visich, Eric P. Hoffman, Paul M. Gordon, 2013, Journals of Gerontology - Series A Biological Sciences and Medical Sciences on p. 1035-1044

Effects of immunosuppressive treatment on interleukin-15 and interleukin-15 receptor α expression in muscle tissue of patients with polymyositis or dermatomyositis

Mei Zong, Ingela Loell, Eva Lindroos, Gustavo Alberto Nader, Helene Alexanderson, Christina Ståhl Hallengren, Kristian Borg, Snjolaug Arnardottir, Iain B. McInnes, Ingrid E. Lundberg, 2012, Annals of the Rheumatic Diseases on p. 1055-1063