Gregory Yochum

Assoc. Professor, Biochemistry

Gregory Yochum

Huck Affiliations

Publication Tags

Crohn Disease Gene Expression Catenins Diverticulitis Genes Epithelial Cells Proteins Single Nucleotide Polymorphism Colorectal Neoplasms Beta Catenin Bilirubin Ulcerative Colitis Alleles Inflammatory Bowel Diseases Transcription Factors Dna Recurrence Therapeutics Colitis Mucous Membrane Nucleotides Fibroblasts Inflammation Diverticular Diseases Homeostasis

Most Recent Papers

BRD4-MK2 signaling

Marina Chulkina, Steven McAninch, Yi Li, Walter Koltun, Gregory Yochum, Bing Tian, Jia Zhou, Ellen J. Beswick, Allan R. Brasier, Irina V. Pinchuk, 2022, FASEB Journal

PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression

Emmanuel K. Teye, Shasha Lu, Fangyuan Chen, Wenrui Yang, Thomas Abraham, Douglas B. Stairs, Hong Gang Wang, Gregory S. Yochum, Robert A. Brodsky, Jeffrey J. Pu, 2021, Scientific Reports

Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease

Carl Grim, Robert Noble, Gabriela Uribe, Kamil Khanipov, Paul Johnson, Walter A. Koltun, Tammara Watts, Yuriy Fofanov, Gregory S. Yochum, Don W. Powell, Ellen J. Beswick, Irina V. Pinchuk, 2021, Journal of Crohn's and Colitis on p. 1362-1375

Clinical and Genetic Factors Impact Time to Surgical Recurrence After Ileocolectomy for Crohn's Disease

Bryan P. Kline, Taelor Weaver, David L. Brinton, Leonard Harris, Gregory S. Yochum, Arthur S. Berg, Walter A. Koltun, 2021, Annals of Surgery on p. 346-351

Clinical and Genetic Factors Associated With Complications After Crohn's Ileocolectomy

Bryan P. Kline, Taelor Weaver, David L. Brinton, Sue Deiling, Gregory S. Yochum, Arthur S. Berg, Walter A. Koltun, 2020, Diseases of the Colon and Rectum on p. 357-364

Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90<sup>+</sup> (myo-)fibroblasts in Crohn’s disease and regulate T<sub>h</sub>1/T<sub>h</sub>17 cell responses

Jose E. Aguirre, Ellen J. Beswick, Carl Grim, Gabriela Uribe, Marissa Tafoya, Gabriela Chacon Palma, Von Samedi, Rohini McKee, Romain Villeger, Yuriy Fofanov, Yingzi Cong, Gregory Yochum, Walter Koltun, Don Powell, Irina V. Pinchuk, 2020, International Immunology on p. 57-68

Tristetraprolin targets Nos2 expression in the colonic epithelium

Melanie A. Eshelman, Stephen M. Matthews, Emily M. Schleicher, Rebecca M. Fleeman, Yuka Imamura Kawasawa, Deborah J. Stumpo, Perry J. Blackshear, Walter A. Koltun, Faoud T. Ishmael, Gregory S. Yochum, 2019, Scientific Reports

Multifocal Versus Conventional Unifocal Diverticulitis

Bryan P. Kline, Kathleen M. Schieffer, Christine S. Choi, Tara Connelly, Jeffrey Chen, Leonard Harris, Sue Deiling, Gregory S. Yochum, Walter A. Koltun, 2019, Digestive Diseases and Sciences on p. 3143-3151

The Crohn’s disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells

Stephen M. Matthews, Melanie A. Eshelman, Arthur S. Berg, Walter A. Koltun, Gregory S. Yochum, 2019, PLoS One

A differential host response to viral infection defines a subset of earlier-onset diverticulitis patients

Kathleen M. Schieffer, Bryan P. Kline, Leonard R. Harris, Sue Deiling, Walter A. Koltun, Gregory S. Yochum, 2018, Journal of Gastrointestinal and Liver Diseases on p. 249-255

Most-Cited Papers

Wnt/β-catenin signaling regulates yes-associated protein (YAP) gene expression in colorectal carcinoma cells

Wesley M. Konsavage, Sydney L. Kyler, Sherri A. Rennoll, Ge Jin, Gregory S. Yochum, 2012, Journal of Biological Chemistry on p. 11730-11739

Intersection of Hippo/YAP and Wnt/β-catenin signaling pathways

Wesley M. Konsavage, Gregory S. Yochum, 2013, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica on p. 71-79

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia

C. Song, X. Pan, Z. Ge, C. Gowda, Y. Ding, H. Li, Z. Li, G. Yochum, M. Muschen, Q. Li, K. J. Payne, S. Dovat, 2016, Leukemia on p. 1436-1440

A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells

Meera Shah, Sherri A. Rennoll, Wesley M. Raup-Konsavage, Gregory S. Yochum, 2015, Cell Cycle on p. 323-332

Review article

K. M. Schieffer, E. D. Williams, G. S. Yochum, W. A. Koltun, 2016, Alimentary Pharmacology and Therapeutics on p. 817-835

The Microbial Ecosystem Distinguishes Chronically Diseased Tissue from Adjacent Tissue in the Sigmoid Colon of Chronic, Recurrent Diverticulitis Patients

Kathleen M. Schieffer, Kate Sabey, Justin R. Wright, David R. Toole, Rebecca Drucker, Vasily Tokarev, Leonard R. Harris, Sue Deiling, Melanie A. Eshelman, John P. Hegarty, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, David B. Stewart, 2017, Scientific Reports

Synthetic cannabinoid activity against colorectal cancer cells

Wesley M. Raup-Konsavage, Megan Johnson, Christopher A. Legare, Gregory S. Yochum, Daniel J. Morgan, Kent E. Vrana, 2018, Cannabis and Cannabinoid Research on p. 272-281

Reduced total serum bilirubin levels are associated with ulcerative colitis

Kathleen M. Schieffer, Shannon M. Bruffy, Richard Rauscher, Walter A. Koltun, Gregory S. Yochum, Carla J. Gallagher, 2017, PLoS One

Pathophysiology of diverticular disease

Kathleen M. Schieffer, Bryan P. Kline, Gregory Yochum, Walter Koltun, 2018, Expert Review of Gastroenterology and Hepatology on p. 683-692

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing

Joel L. Coble, Feng Yue, Tarik J. Salameh, Leonard R. Harris, Sue Deiling, Francesca M. Ruggiero, Melanie A. Eshelman, Gregory S. Yochum, Walter A. Koltun, Glenn S. Gerhard, James R. Broach, 2017, Human Molecular Genetics on p. 3212-3220