Gregory Yochum

Assoc. Professor, Biochemistry

Gregory Yochum

Huck Affiliations

Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Catenin Bilirubin Colorectal Neoplasms Neoplasms Diverticulitis Liver Permeability Catenins Tight Junctions Cancer Cell Ulcerative Colitis Therapeutics Carcinogenesis Colitis Growth T Cell Reactive Oxygen Metabolite Diverticular Diseases Messenger Rna Dynamic Exchange Extrusion Serum Stellate Crystal Transcription Factor 4 Neoplasm Metastasis

Most Recent Publications

The microbiome of diverticulitis

N Jeganathan, E Davenport, Gregory Yochum, W Koltun, Current Opinion Physiology

Mucin MUC5B levels are reduced in the colonic epithelia of ulcerative colitis patients

W Ding, W Koltun, Gregory Yochum, bioRxiv : the preprint server for biology

The Wnt/beta-catenin pathway is activated by miR-1246 in liver cancer stem cells

Melanie Eshelman, Gregory Yochum, Translational cancer research on p. S1457-S1460

AXIN2: Oncogene or tumor suppressor in colorectal carcinoma?

Gregory Yochum, Journal of Cancer Science and Therapy

TCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression

Carli M. King, Wei Ding, Melanie A. Eshelman, Gregory S. Yochum, 2024, Scientific Reports

Increased activity of MAPKAPK2 within mesenchymal cells as a target for inflammation associated fibrosis in Crohn's Disease.

M Chulkina, C Rohmer, S McAninch, R Panganiban, R Villéger, A Portolese, J Ciocirlan, W Yang, C Cohen, W Koltun, J Valentine, Y Cong, Gregory Yochum, E Beswick, Iryna Pinchuk, 2024, Journal of Crohn's & colitis

Disease Severity Impairs Generation of Intestinal Organoid Cultures From Inflammatory Bowel Disease Patients

Wei Ding, Olivia M. Marx, Marc M. Mankarious, Walter A. Koltun, Gregory S. Yochum, 2024, Journal of Surgical Research on p. 187-195

Identification of differentially expressed genes and splicing events in early-onset colorectal cancer

Olivia M. Marx, Marc M. Mankarious, Walter A. Koltun, Gregory S. Yochum, 2024, Frontiers in Oncology

Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis

Sonal Sinha, Satoka Aizawa, Yasuhiro Nakano, Alexander Rialdi, Hye Yeon Choi, Rajan Shrestha, Stephanie Q. Pan, Yibu Chen, Meng Li, Audrey Kapelanski-Lamoureux, Gregory Yochum, Linda Sher, Satdarshan Paul Monga, Anthoula Lazaris, Keigo Machida, Michael Karin, Ernesto Guccione, Hidekazu Tsukamoto, 2023, Nature Communications

Control of Paneth cell function by HuR regulates gut mucosal growth by altering stem cell activity

Lan Xiao, Bridgette Warner, Caroline G. Mallard, Hee K. Chung, Amol Shetty, Christine A. Brantner, Jaladanki N. Rao, Gregory S. Yochum, Walter A. Koltun, Kathleen B. To, Douglas J. Turner, Myriam Gorospe, Jian Ying Wang, 2023, Life Science Alliance

Most-Cited Papers

IL1B Increases Intestinal Tight Junction Permeability by Up-regulation of MIR200C-3p, Which Degrades Occludin mRNA

M Rawat, K Rawat, Walter Koltun, Meghali Nighot, G Yochum, Rana Al-Sadi, Y Gupta, D Viszwapriya, Gregory Yochum, Thomas Y. Ma, 2020, Gastroenterology on p. 1375-1389

The Microbial Ecosystem Distinguishes Chronically Diseased Tissue from Adjacent Tissue in the Sigmoid Colon of Chronic, Recurrent Diverticulitis Patients

Kathleen M. Schieffer, Kate Sabey, Justin R. Wright, David R. Toole, Rebecca Drucker, Vasily Tokarev, Leonard R. Harris, Sue Deiling, Melanie A. Eshelman, John P. Hegarty, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, David B. Stewart, 2017, Scientific Reports

Review article: the pathogenesis of pouchitis

K Schieffer, Emmanuelle Williams, G. S. Yochum, W. A. Koltun, 2016, Alimentary Pharmacology and Therapeutics on p. 817-835

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia

C. Song, X. Pan, Z. Ge, C. Gowda, Y. Ding, H. Li, Z. Li, G. Yochum, M. Muschen, Q. Li, K. J. Payne, S. Dovat, 2016, Leukemia on p. 1436-1440

A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells

Meera Shah, Sherri Rennoll, Wesley Raup-Konsavage, Gregory Yochum, 2015, Cell Cycle on p. 323-332

Pathophysiology of diverticular disease

Kathleen Schieffer, Bryan Kline, Gregory Yochum, Walter Koltun, 2018, Expert Review of Gastroenterology and Hepatology on p. 683-692

Dichotomous role of the human mitochondrial na<sup>+</sup> /ca2<sup>+</sup> /li<sup>+</sup> exchanger nclx in colorectal cancer growth and metastasis

Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin Johnson, Xuexin Zhang, Ping Xin, Ryan Yoast, Scott Emrich, Gregory S. Yochum, Israel Sekler, Walter Koltun, Donald L. Gill, N Hempel, M Trebak, 2020, eLife on p. 1-41

AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability

A Ganapathy, K Saha, E Suchanec, V Singh, A Verma, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot, 2021, Autophagy on p. 1-18

Reduced total serum bilirubin levels are associated with ulcerative colitis

Kathleen M. Schieffer, Shannon M. Bruffy, Richard Rauscher, Walter A. Koltun, Gregory S. Yochum, Carla J. Gallagher, 2017, PLoS One

Synthetic cannabinoid activity against colorectal cancer cells

Wesley Raup-Konsavage, Megan Johnson, Christopher Legare, Gregory Yochum, D Morgan, Kent E. Vrana, 2018, Cannabis and Cannabinoid Research on p. 272-281