Gregory Yochum

Assoc. Professor, Biochemistry

Gregory Yochum

Huck Affiliations

Publication Tags

Crohn Disease Diverticulitis Proteins Fibrosis Mucous Membrane Myofibroblasts Single Nucleotide Polymorphism Colon Therapeutics Colitis Inflammatory Bowel Diseases Neoplasms Th17 Cells Claudin 2 Gene Expression Profiling Autophagy Protein Leukemia Macrophages Ulcerative Colitis Diverticular Diseases Amphiregulin Tight Junctions Colorectal Neoplasms Mitogen Activated Protein Kinase Kinases

Most Recent Publications

Transcriptome Analyses Identify Deregulated MYC in Early Onset Colorectal Cancer

Olivia M. Marx, Marc M. Mankarious, Melanie A. Eshelman, Wei Ding, Walter A. Koltun, Gregory S. Yochum, 2022, Biomolecules

BRD4-MK2 signaling

Marina Chulkina, Steven McAninch, Yi Li, Walter Koltun, Gregory Yochum, Bing Tian, Jia Zhou, Ellen J. Beswick, Allan R. Brasier, Irina V. Pinchuk, 2022, FASEB Journal

Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts

Xiaojing Zhao, Wenjing Yang, Tianming Yu, Yu Yu, Xiufang Cui, Zheng Zhou, Hui Yang, Yanbo Yu, Anthony J. Bilotta, Suxia Yao, Jimin Xu, Jia Zhou, Gregory S. Yochum, Walter A. Koltun, Austin Portolese, Defu Zeng, Jingwu Xie, Iryna V. Pinchuk, Hongjie Zhang, Yingzi Cong, 2022, Gastroenterology

PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression

Emmanuel K. Teye, Shasha Lu, Fangyuan Chen, Wenrui Yang, Thomas Abraham, Douglas B. Stairs, Hong Gang Wang, Gregory S. Yochum, Robert A. Brodsky, Jeffrey J. Pu, 2021, Scientific Reports

Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease

C Grim, R Noble, G Uribe, K Khanipov, P Johnson, Walter A. Koltun, T Watts, Y Fofanov, Gregory S. Yochum, D Powell, E Beswick, Iryna Pinchuk, 2021, Journal of Crohn's and Colitis on p. 1362-1375

The microbiome of diverticulitis

Nimlan Arjun Jeganathan, Emily R. Davenport, Gregory S. Yochum, Walter A. Koltun, 2021, Current Opinion in Physiology

AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability

A Ganapathy, K Saha, E Suchanec, V Singh, A Verma, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot, 2021, Autophagy on p. 1-18

Clinical and Genetic Factors Impact Time to Surgical Recurrence After Ileocolectomy for Crohn's Disease

Bryan Kline, Taelor Weaver, David L. Brinton, Brinton, David L., Jr., Leonard Harris, Gregory S. Yochum, Arthur S. Berg, Walter Koltun, 2021, Annals of Surgery on p. 346-351

CD163L1<sup>+</sup>CXCL10<sup>+</sup> Macrophages are Enriched Within Colonic Lamina Propria of Diverticulitis Patients

Kathleen Schieffer, Scott Emrich, Gregory S. Yochum, Walter A. Koltun, 2021, Journal of Surgical Research on p. 527-535

COLQ and ARHGAP15 are associated with diverticular disease and are expressed in the colon

Bryan Kline, Gregory Yochum, D Brinton, Kathleen Schieffer, Taelor Weaver, Leonard Harris, Sue Deiling, Arthur S. Berg, Walter A. Koltun, 2021, Journal of Surgical Research on p. 397-403