Gregory Yochum

Assoc. Professor, Biochemistry

Gregory Yochum

Huck Affiliations

Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Colorectal Neoplasms Diverticulitis Crohn Disease Colitis Bilirubin Tight Junctions Proteins Catenins Neoplasms Protein Occludin Fibrosis Microbiota Carcinogenesis Dna Ulcerative Colitis Permeability Therapeutics Growth Mucous Membrane Diverticular Diseases Serum Tcf Transcription Factors Bacteria Sigmoid Colon

Most Recent Publications

The Microbiome of Complicated Diverticulitis: An Imbalance of Sulfur-Metabolizing Bacteria

Austin C. Portolese, Brittney N. McMullen, Samantha K. Baker, Jeremy R. Chen See, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, Nimalan A. Jeganathan, 2023, Diseases of the Colon and Rectum on p. 707-715

TCF7L1 Regulates LGR5 Expression in Colorectal Cancer Cells

Carli M. King, Olivia M. Marx, Wei Ding, Walter A. Koltun, Gregory S. Yochum, 2023, Genes

Transcriptome Analyses Identify Deregulated MYC in Early Onset Colorectal Cancer

Olivia M. Marx, Marc M. Mankarious, Melanie A. Eshelman, Wei Ding, Walter A. Koltun, Gregory S. Yochum, 2022, Biomolecules

BRD4-MK2 signaling

Marina Chulkina, Steven McAninch, Yi Li, Walter Koltun, Gregory Yochum, Bing Tian, Jia Zhou, Ellen J. Beswick, Allan R. Brasier, Irina V. Pinchuk, 2022, FASEB Journal

Long-Term Use of Proton Pump Inhibitors Disrupts Intestinal Tight Junction Barrier and Exaggerates Experimental Colitis

Meghali Nighot, Pei-Luan Liao, Nathan Morris, Dennis Mccarthy, Viszwapriya Dharmaprakash, Inam Ullah Khan, Ullah Khan, Inam, Inamullah Khan, Shannon Dalessio, Kushal Saha, Prashant Nighot, Thomas Ma, Ashwinkumar Ganapathy, Alexandra Wang, W Ding, Gregory Yochum, Walter Koltun, P Nighot, T Ma, 2022, Journal of Crohn's and Colitis on p. 565-579

Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts

Xiaojing Zhao, Wenjing Yang, Tianming Yu, Yu Yu, Xiufang Cui, Zheng Zhou, H Yang, Yanbo Yu, Anthony Bilotta, Suxia Yao, Jimin Xu, Jia Zhou, Gregory S. Yochum, Walter Koltun, Austin Portolese, Defu Zeng, Jingwu Xie, Iryna V. Pinchuk, Pinchuk, Iryna, V, Hongjie Zhang, Yingzi Cong, 2022, Gastroenterology on p. 89-102

Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux

Kushal Saha, Ashwinkumar Subramenium Ganapathy, Ashwinkumar Ganapathy, Alexandra Wang, Nathan Morris, Nathan Michael Morris, Eric Suchanec, Wei Ding, Gregory Yochum, Walter Koltun, M Nighot, T Ma, Prashant Nighot, 2022, Journal of Crohn's and Colitis on p. 433-449

PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression

Emmanuel K. Teye, Shasha Lu, Fangyuan Chen, Wenrui Yang, Thomas Abraham, Douglas B. Stairs, Hong Gang Wang, Gregory S. Yochum, Robert A. Brodsky, Jeffrey J. Pu, 2021, Scientific Reports

CD163L1<sup>+</sup>CXCL10<sup>+</sup> Macrophages are Enriched Within Colonic Lamina Propria of Diverticulitis Patients

Kathleen Schieffer, Scott Emrich, Gregory S. Yochum, Walter A. Koltun, 2021, Journal of Surgical Research on p. 527-535

Clinical and Genetic Factors Impact Time to Surgical Recurrence After Ileocolectomy for Crohn's Disease

Bryan Kline, Taelor Weaver, Brinton, David L., Jr., David L. Brinton, Leonard Harris, Gregory S. Yochum, Arthur S. Berg, Walter Koltun, 2021, Annals of Surgery on p. 346-351

Most-Cited Papers

Intersection of Hippo/YAP and Wnt/β-catenin signaling pathways

Konsavage, Wesley M., Jr., Wesley M. Konsavage, Gregory Yochum, 2013, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica on p. 71-79

IL1B Increases Intestinal Tight Junction Permeability by Up-regulation of MIR200C-3p, Which Degrades Occludin mRNA

M Rawat, K Rawat, Walter Koltun, Meghali Nighot, G Yochum, Rana Al-Sadi, Y Gupta, D Viszwapriya, Gregory Yochum, Thomas Y. Ma, 2020, Gastroenterology on p. 1375-1389

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia

C. Song, X. Pan, Z. Ge, C. Gowda, Y. Ding, H. Li, Z. Li, G. Yochum, M. Muschen, Q. Li, K. J. Payne, S. Dovat, 2016, Leukemia on p. 1436-1440

The Microbial Ecosystem Distinguishes Chronically Diseased Tissue from Adjacent Tissue in the Sigmoid Colon of Chronic, Recurrent Diverticulitis Patients

Kathleen M. Schieffer, Kate Sabey, Justin R. Wright, David R. Toole, Rebecca Drucker, Vasily Tokarev, Leonard R. Harris, Sue Deiling, Melanie A. Eshelman, John P. Hegarty, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, David B. Stewart, 2017, Scientific Reports

A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells

Meera Shah, Sherri Rennoll, Wesley Raup-Konsavage, Gregory Yochum, 2015, Cell Cycle on p. 323-332

Review article: the pathogenesis of pouchitis

K. M. Schieffer, E. D. Williams, G. S. Yochum, W. A. Koltun, 2016, Alimentary Pharmacology and Therapeutics on p. 817-835

Reduced total serum bilirubin levels are associated with ulcerative colitis

Kathleen M. Schieffer, Shannon M. Bruffy, Richard Rauscher, Walter A. Koltun, Gregory S. Yochum, Carla J. Gallagher, 2017, PLoS One

Pathophysiology of diverticular disease

Kathleen Schieffer, Bryan Kline, Gregory Yochum, Walter Koltun, 2018, Expert Review of Gastroenterology and Hepatology on p. 683-692

Dichotomous role of the human mitochondrial na<sup>+</sup> /ca2<sup>+</sup> /li<sup>+</sup> exchanger nclx in colorectal cancer growth and metastasis

Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin Johnson, Xuexin Zhang, Ping Xin, Ryan Yoast, Scott Emrich, Gregory S. Yochum, Israel Sekler, Walter Koltun, Donald L. Gill, N Hempel, M Trebak, 2020, eLife on p. 1-41

Synthetic cannabinoid activity against colorectal cancer cells

Wesley Raup-Konsavage, Megan Johnson, Christopher Legare, Gregory Yochum, D Morgan, Kent E. Vrana, 2018, Cannabis and Cannabinoid Research on p. 272-281