Gregory Yochum

Assoc. Professor, Biochemistry

Gregory Yochum

Huck Affiliations

Publication Tags

Catenins Diverticulitis Proteins Crohn Disease Beta Catenin Messenger Rna Occludin Protein Bilirubin Colorectal Neoplasms Gene Expression Ulcerative Colitis Homeostasis Mucous Membrane Diverticular Diseases Carrier Proteins Insulin Like Growth Factor Binding Protein 2 Microbiota Dna Colitis Genes Cells Growth Carcinogenesis Therapeutics

Most Recent Papers

PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression

Emmanuel K. Teye, Shasha Lu, Fangyuan Chen, Wenrui Yang, Thomas Abraham, Douglas B. Stairs, Hong Gang Wang, Gregory S. Yochum, Robert A. Brodsky, Jeffrey J. Pu, 2021, Scientific Reports

COLQ and ARHGAP15 are associated with diverticular disease and are expressed in the colon

Bryan P. Kline, Gregory S. Yochum, David L. Brinton, Kathleen M. Schieffer, Taelor Weaver, Leonard Harris, Sue Deiling, Arthur S. Berg, Walter A. Koltun, 2021, Journal of Surgical Research on p. 397-403

CD163L1<sup>+</sup>CXCL10<sup>+</sup> Macrophages are Enriched Within Colonic Lamina Propria of Diverticulitis Patients

Kathleen M. Schieffer, Scott M. Emrich, Gregory S. Yochum, Walter A. Koltun, 2021, Journal of Surgical Research on p. 527-535

Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn's Disease

Carl Grim, Robert Noble, Gabriela Uribe, Kamil Khanipov, Paul Johnson, Walter A. Koltun, Tammara Watts, Yuriy Fofanov, Gregory S. Yochum, Don W. Powell, Ellen J. Beswick, Irina V. Pinchuk, 2021, Journal of Crohn's and Colitis on p. 1362-1375

Clinical and Genetic Factors Impact Time to Surgical Recurrence After Ileocolectomy for Crohn's Disease

Bryan P. Kline, Taelor Weaver, David L. Brinton, Leonard Harris, Gregory S. Yochum, Arthur S. Berg, Walter A. Koltun, 2021, Annals of Surgery on p. 346-351

The microbiome of diverticulitis

Nimlan Arjun Jeganathan, Emily R. Davenport, Gregory S. Yochum, Walter A. Koltun, 2021, Current Opinion in Physiology

IL1B Increases Intestinal Tight Junction Permeability by Up-regulation of MIR200C-3p, Which Degrades Occludin mRNA

Manmeet Rawat, Meghali Nighot, Rana Al-Sadi, Yash Gupta, Dharmaprakash Viszwapriya, Gregory Yochum, Walter Koltun, Thomas Y. Ma, 2020, Gastroenterology on p. 1375-1389

Transcriptomic analysis of ileal tissue from crohn’s disease patients identifies extracellular matrix genes that distinguish individuals by age at diagnosis

Melanie A. Eshelman, Leonard Harris, Sue Deiling, Walter A. Koltun, N. Arjun Jeganathan, Gregory S. Yochum, 2020, Physiological Genomics on p. 478-484

Dichotomous role of the human mitochondrial na<sup>+</sup> /ca2<sup>+</sup> /li<sup>+</sup> exchanger nclx in colorectal cancer growth and metastasis

Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T. Johnson, Xuexin Zhang, Ping Xin, Ryan E. Yoast, Scott M. Emrich, Gregory S. Yochum, Israel Sekler, Walter A. Koltun, Donald L. Gill, Nadine Hempel, Mohamed Trebak, 2020, eLife on p. 1-41

The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression

Vikash Singh, Chethana P. Gowda, Vishal Singh, Ashwinkumar S. Ganapathy, Dipti M. Karamchandani, Melanie A. Eshelman, Gregory S. Yochum, Prashant Nighot, Vladimir S. Spiegelman, 2020, Journal of Biological Chemistry on p. 8602-8612

Most-Cited Papers

Wnt/β-catenin signaling regulates yes-associated protein (YAP) gene expression in colorectal carcinoma cells

Wesley M. Konsavage, Sydney L. Kyler, Sherri A. Rennoll, Ge Jin, Gregory S. Yochum, 2012, Journal of Biological Chemistry on p. 11730-11739

Intersection of Hippo/YAP and Wnt/β-catenin signaling pathways

Wesley M. Konsavage, Gregory S. Yochum, 2013, Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica on p. 71-79

Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia

C. Song, X. Pan, Z. Ge, C. Gowda, Y. Ding, H. Li, Z. Li, G. Yochum, M. Muschen, Q. Li, K. J. Payne, S. Dovat, 2016, Leukemia on p. 1436-1440

A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells

Meera Shah, Sherri A. Rennoll, Wesley M. Raup-Konsavage, Gregory S. Yochum, 2015, Cell Cycle on p. 323-332

Review article

K. M. Schieffer, E. D. Williams, G. S. Yochum, W. A. Koltun, 2016, Alimentary Pharmacology and Therapeutics on p. 817-835

The Microbial Ecosystem Distinguishes Chronically Diseased Tissue from Adjacent Tissue in the Sigmoid Colon of Chronic, Recurrent Diverticulitis Patients

Kathleen M. Schieffer, Kate Sabey, Justin R. Wright, David R. Toole, Rebecca Drucker, Vasily Tokarev, Leonard R. Harris, Sue Deiling, Melanie A. Eshelman, John P. Hegarty, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, David B. Stewart, 2017, Scientific Reports

Reduced total serum bilirubin levels are associated with ulcerative colitis

Kathleen M. Schieffer, Shannon M. Bruffy, Richard Rauscher, Walter A. Koltun, Gregory S. Yochum, Carla J. Gallagher, 2017, PLoS One

Pathophysiology of diverticular disease

Kathleen M. Schieffer, Bryan P. Kline, Gregory Yochum, Walter Koltun, 2018, Expert Review of Gastroenterology and Hepatology on p. 683-692

The Myc 3'wnt-responsive element regulates homeostasis and regeneration in the mouse intestinal tract

Wesley M. Konsavage, Ge Jin, Gregory S. Yochum, 2012, Molecular and Cellular Biology on p. 3891-3902

RNA-seq implicates deregulation of the immune system in the pathogenesis of diverticulitis

Kathleen M. Schieffer, Christine S. Choi, Scott Emrich, Leonard Harris, Sue Deiling, Dipti M. Karamchandani, Anna Salzberg, Yuka I. Kawasawa, Gregory S. Yochum, Walter A. Koltun, 2017, American Journal of Physiology on p. G277-G284