George Perry
Chair, Intercollege Graduate Degree Program in Bioinformatics and Genomics; Associate Professor of Anthropology and Biology
-
513 Carpenter
University Park, PA 16802 - He/Him
- ghp3@psu.edu
Research Summary
Anthropological genomics, paleogenomics, human body size evolution, parasite evolution, and evolutionary medicine.
Huck Graduate Students
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Publication Tags
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Genome Genes History Body Size Population Agriculture Genomics Phenotype Madagascar Single Nucleotide Polymorphism Rainforest Ecology Human Body Human Behavior Natural Selection Chromosomes Brain Lemur Extinction Farmers Longevity Temperature Primates Habitat DnaMost Recent Publications
An integrative skeletal and paleogenomic analysis of stature variation suggests relatively reduced health for early European farmers
Stephanie Marciniak, Christina M. Bergey, Ana Maria Silva, Agata Hałuszko, Mirosław Furmanek, Barbara Veselka, Petr Velemínský, Giuseppe Vercellotti, Joachim Wahl, Gunita Zariņa, Cristina Longhi, Jan Kolář, Rafael Garrido-Pena, Raúl Flores-Fernández, Ana M. Herrero-Corral, Angela Simalcsik, Werner Müller, Alison Sheridan, Žydrūnė Miliauskienė, Rimantas Jankauskas, Vyacheslav Moiseyev, Kitti Köhler, Ágnes Király, Beatriz Gamarra, Olivia Cheronet, Vajk Szeverényi, Viktória Kiss, Tamás Szeniczey, Krisztián Kiss, Zsuzsanna K. Zoffmann, Judit Koós, Magdolna Hellebrandt, Robert M. Maier, László Domboróczki, Cristian Virag, Mario Novak, David Reich, Tamás Hajdu, Noreen von Cramon-Taubadel, Ron Pinhasi, George H. Perry, 2022, Proceedings of the National Academy of Sciences of the United States of America on p. e2106743119
Potential evolutionary body size reduction in a Malagasy primate (Propithecus verreauxi) in response to human size-selective hunting pressure
Alexis Sullivan, Laurie Godfrey, Richard Lawler, Heritiana Randrianatoandro, Laurie Eccles, B Culleton, Timothy Ryan, G Perry, 2022, American Journal of Biological Anthropology on p. 385-398
A chromosome-level genome assembly for the eastern fence lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology
Aundrea K. Westfall, Rory S. Telemeco, Mariana B. Grizante, Damien S. Waits, Amanda D. Clark, Dasia Y. Simpson, Randy L. Klabacka, Alexis P. Sullivan, George H. Perry, Michael W. Sears, Christian L. Cox, Robert M. Cox, Matthew E. Gifford, Henry B. John-Alder, Tracy Langkilde, Michael J. Angilletta, Adam D. Leaché, Marc Tollis, Kenro Kusumi, Tonia S. Schwartz, 2021, GigaScience
Erratum: The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS (Proc. Natl. Acad. Sci. U.S.A. (2021) 118 (e2010632118) DOI: 10.1073/pnas.2010632118)
Joseph D. Orkin, Michael J. Montague, Daniela Tejada-Martinez, Marc de Manuel, Javier del Campo, Saul Cheves Hernandez, Anthony Di Fiore, Claudia Fontsere, Jason A. Hodgson, Mareike C. Janiak, Lukas F.K. Kuderna, Esther Lizano, Maria Pia Martin, Yoshihito Niimura, George H. Perry, Carmen Soto Valverde, Jia Tang, Wesley C. Warren, João Pedro de Magalhães, Shoji Kawamura, Tomàs Marquès-Bonet, Roman Krawetz, Amanda D. Melin, 2021, Proceedings of the National Academy of Sciences of the United States of America
Evolutionary medicine
George H. Perry, 2021, eLife
Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, “subfossil” koala lemur Megaladapis edwardsi
Stephanie Marciniak, Mehreen R. Mughal, Laurie R. Godfrey, Richard J. Bankoff, Heritiana Randrianatoandro, Brooke E. Crowley, Christina M. Bergey, Kathleen M. Muldoon, Jeannot Randrianasy, Brigitte M. Raharivololona, Stephan C. Schuster, Ripan S. Malhi, Anne D. Yoder, Edward E. Louis, Logan Kistler, George H. Perry, 2021, Proceedings of the National Academy of Sciences of the United States of America
Patterns of recent natural selection on genetic loci associated with sexually differentiated human body size and shape phenotypes
A Arner, K Grogan, M Grabowski, H Reyes-Centeno, George Perry, 2021, PLoS Genetics on p. e1009562
A common 1.6 mb Y-chromosomal inversion predisposes to subsequent deletions and severe spermatogenic failure in humans
Pille Hallast, Laura Kibena, Margus Punab, Elena Arciero, Siiri Rootsi, Marina Grigorova, Rodrigo Flores, Mark A. Jobling, Olev Poolamets, Kristjan Pomm, Paul Korrovits, Kristiina Rull, Yali Xue, Chris Tyler-Smith, Maris Laan, George H. Perry, 2021, eLife
Scanning the human genome for “signatures” of positive selection: Transformative opportunities and ethical obligations
Margarita Hernandez, George H. Perry, 2021, Evolutionary Anthropology on p. 113-121
The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS
Joseph D. Orkin, Michael J. Montague, Daniela Tejada-Martinez, Marc de Manuel, Javier del Campo, Saul Cheves Hernandez, Anthony Di Fiore, Claudia Fontsere, Jason A. Hodgson, Mareike C. Janiak, Lukas F.K. Kuderna, Esther Lizano, Maria Pia Martin, Yoshihito Niimura, George H. Perry, Carmen Soto Valverde, Jia Tang, Wesley C. Warren, João Pedro de Magalhães, Shoji Kawamura, Tomàs Marquès-Bonet, Roman Krawetz, Amanda D. Melin, 2021, Proceedings of the National Academy of Sciences of the United States of America
Most-Cited Papers
Archaeogenomic evidence reveals prehistoric matrilineal dynasty
Douglas J. Kennett, Stephen Plog, Richard J. George, Brendan J. Culleton, Adam S. Watson, Pontus Skoglund, Nadin Rohland, Swapan Mallick, Kristin Stewardson, Logan Kistler, Steven A. Leblanc, Peter M. Whiteley, David Reich, George H. Perry, 2017, Nature Communications
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Etienne Patin, Marie Lopez, Rebecca Grollemund, Paul Verdu, Christine Harmant, Hélène Quach, Guillaume Laval, George H. Perry, Luis B. Barreiro, Alain Froment, Evelyne Heyer, Achille Massougbodji, Cesar Fortes-Lima, Florence Migot-Nabias, Gil Bellis, Jean Michel Dugoujon, Joana B. Pereira, Verónica Fernandes, Luisa Pereira, Lolke Van Der Veen, Patrick Mouguiama-Daouda, Carlos D. Bustamante, Jean Marie Hombert, Lluís Quintana-Murci, 2017, Science on p. 543-546
Transposable elements are the primary source of novelty in primate gene regulation
Marco Trizzino, Yo Son Park, Marcia Holsbach-Beltrame, Katherine Aracena, Katelyn Mika, Minal Caliskan, George H. Perry, Vincent J. Lynch, Christopher D. Brown, 2017, Genome Research on p. 1623-1633
Human behaviour as a long-term ecological driver of non-human evolution
Alexis P. Sullivan, Douglas W. Bird, George H. Perry, 2017, Nature Ecology and Evolution
Harnessing ancient genomes to study the history of human adaptation
Stephanie Marciniak, George H. Perry, 2017, Nature Reviews Genetics on p. 659-674
Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic
Vincent J. Lynch, Oscar C. Bedoya-Reina, Aakrosh Ratan, Michael Sulak, Daniela I. Drautz-Moses, George H. Perry, Webb Miller, Stephan C. Schuster, 2015, Cell Reports on p. 217-228
Gourds and squashes (Cucurbita spp.) adapted to megafaunal extinction and ecological anachronism through domestication
Logan Kistlera, Lee A. Newsoma, Timothy M. Ryana, Andrew C. Clarke, Bruce D. Smith, George H. Perry, 2015, Proceedings of the National Academy of Sciences of the United States of America on p. 15107-15112
The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists
Etienne Patin, Katherine J. Siddle, Guillaume Laval, Hélène Quach, Christine Harmant, Noémie Becker, Alain Froment, Béatrice Régnault, Laure Lemée, Simon Gravel, Jean Marie Hombert, Lolke Van Der Veen, Nathaniel J. Dominy, George H. Perry, Luis B. Barreiro, Paul Verdu, Evelyne Heyer, Lluís Quintana-Murci, 2014, Nature Communications
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers
George H. Perry, Matthieu Foll, Jean Christophe Grenier, Etienne Patin, Yohann Nédélec, Alain Pacis, Maxime Barakatt, Simon Gravel, Xiang Zhou, Sam L. Nsobya, Laurent Excoffier, Lluis Quintana-Murci, Nathaniel J. Dominy, Luis B. Barreiro, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. E3596-E3603
Comparative and population mitogenomic analyses of Madagascar's extinct, giant 'subfossil' lemurs
Logan Kistler, Aakrosh Ratan, Laurie R. Godfrey, Brooke E. Crowley, Cris E. Hughes, Runhua Lei, Yinqiu Cui, Mindy L. Wood, Kathleen M. Muldoon, Haingoson Andriamialison, John J. McGraw, Lynn P. Tomsho, Stephan C. Schuster, Webb Miller, Edward E. Louis, Anne D. Yoder, Ripan S. Malhi, George H. Perry, 2015, Journal of Human Evolution on p. 45-54
News Articles Featuring George Perry
Feb 21, 2023
NIH grant allows grad student to study Cuban, Cuban-American health disparities
Growing up in Miami’s Cuban American community, Margarita “Maggie” Hernandez said she often felt “like I wasn’t Cuban enough, but also not American enough.” Today, though, she’s beyond proud of her roots — so much so that she’s made it a hallmark of her research.
Full Article
Jun 30, 2022
Graduate students awarded 2022 NASA Space Grant Fellowships
Seventeen Penn State graduate students have received 2022 NASA Pennsylvania Space Grant awards and been named graduate fellows.
Full Article
Apr 07, 2022
First European farmers' heights did not meet expectations
A combined study of genetics and skeletal remains shows that the switch from primarily hunting, gathering and foraging to farming about 12,000 years ago in Europe may have had negative health effects as indicated by shorter than expected heights in the earliest farmers, according to an international team of researchers.
Full Article
Jun 22, 2021
Newly sequenced genome of extinct giant lemur sheds light on animal's biology
Using an unusually well-preserved subfossil jawbone, a team of researchers — led by Penn State and with a multi-national team of collaborators including scientists from the Université d’Antananarivo in Madagascar — has sequenced for the first time the nuclear genome of the koala lemur (Megaladapis edwardsi), one of the largest of the 17 or so giant lemur species that went extinct on the island of Madagascar between about 500 and 2,000 years ago.
Full Article
Aug 05, 2019
New Bioinformatics and Genomics Chair Looks To Capitalize on Program's Strengths
New chair George Perry is considering opportunities for expanded partnerships that will build on the solid foundations already in place in the BG program.
Full Article
May 07, 2019
Institutes of Energy and the Environment announces seed grant recipients
Several Huck researchers are among the recipients of 2018-19 IEE seed grants.
Full Article