Francesca Chiaromonte

Director of the Genome Sciences Institute; Huck Chair in Statistics for the Life Sciences; Professor of Statistics

Francesca Chiaromonte

Research Summary

Developing methods for the analysis of large, high-dimensional and complex data.

Huck Affiliations

Links

Most Recent Papers

Evidence for sharp increase in the economic damages of extreme natural disasters

Matteo Coronese, Francesco Lamperti, Klaus Keller, Francesca Chiaromonte, Andrea Roventini, 2019, Proceedings of the National Academy of Sciences of the United States of America on p. 21450-21455

Covariate Information Matrix for Sufficient Dimension Reduction

Weixin Yao, Debmalya Nandy, Bruce G. Lindsay, Francesca Chiaromonte, 2019, Journal of the American Statistical Association on p. 1752-1764

Functional data analysis for computational biology

Marzia Cremona, Hongyan Xu, Kateryna Dmytrivna Makova, Matthew Logan Reimherr, Francesca Chiaromonte, Pedro Madrigal, 2019, Bioinformatics on p. 3211-3213

IWTomics

Marzia Cremona, Alessia Pini, Fabio Cumbo, Kateryna Dmytrivna Makova, Francesca Chiaromonte, Simone Vantini, 2018, Bioinformatics on p. 2289-2291

Computational pan-genomics

Tobias Marschall, Manja Marz, Thomas Abeel, Louis Dijkstra, Bas E. Dutilh, Ali Ghaffaari, Paul Kersey, Wigard P. Kloosterman, Veli Mäkinen, Adam M. Novak, Benedict Paten, David Porubsky, Eric Rivals, Can Alkan, Jasmijn A. Baaijens, Paul I.W. De Bakker, Valentina Boeva, Raoul J.P. Bonnal, Francesca Chiaromonte, Rayan Chikhi, Francesca D. Ciccarelli, Robin Cijvat, Erwin Datema, Cornelia M. Van Duijn, Evan E. Eichler, Corinna Ernst, Eleazar Eskin, Erik Garrison, Mohammed El-Kebir, Gunnar W. Klau, Jan O. Korbel, Eric Wubbo Lameijer, Benjamin Langmead, Marcel Martin, Paul Medvedev, John C. Mu, Pieter Neerincx, Klaasjan Ouwens, Pierre Peterlongo, Nadia Pisanti, Sven Rahmann, Ben Raphael, Knut Reinert, Dick de Ridder, Jeroen de Ridder, Matthias Schlesner, Ole Schulz-Trieglaff, Ashley D. Sanders, Siavash Sheikhizadeh, Carl Shneider, 2018, Briefings in bioinformatics on p. 118-135

Structured Ordinary Least Squares

Yang Liu, Francesca Chiaromonte, Bing Li, 2017, Biometrics on p. 529-539

Composite Likelihood Inference in a Discrete Latent Variable Model for Two-Way “Clustering-by-Segmentation” Problems

Francesco Bartolucci, Francesca Chiaromonte, Prabhani Kuruppumullage Don, Bruce G. Lindsay, 2017, Journal of Computational and Graphical Statistics on p. 388-402

Mixture-based path clustering for synthesis of ECMWF ensemble forecasts of tropical cyclone evolution

Prabhani Kuruppumullage Don, Jenni Evans, Francesca Chiaromonte, Alex M. Kowaleski, 2016, Monthly Weather Review on p. 3301-3320

Error correction and statistical analyses for intra-host comparisons of feline immunodeficiency virus diversity from high-throughput sequencing data

Yang Liu, Francesca Chiaromonte, Howard Ross, Raunaq Malhotra, Daniel Elleder, Mary Poss, 2015, BMC bioinformatics

An attraction-repulsion point process model for respiratory syncytial virus infections

Joshua Goldstein, Murali Haran, Ivan Simeonov, John Fricks, Francesca Chiaromonte, 2015, Biometrics on p. 376-385

Most-Cited Papers

Complete Khoisan and Bantu genomes from southern Africa

Stephan C. Schuster, Webb Miller, Aakrosh Ratan, Lynn P. Tomsho, Belinda Giardine, Lindsay R. Kasson, Robert S. Harris, Desiree C. Petersen, Fangqing Zhao, Ji Qi, Can Alkan, Jeffrey M. Kidd, Yazhou Sun, Daniela I. Drautz, Pascal Bouffard, Donna M. Muzny, Jeffrey G. Reid, Lynne V. Nazareth, Qingyu Wang, Richard Burhans, Cathy Riemer, Nicola E. Wittekindt, Priya Moorjani, Elizabeth A. Tindall, Charles G. Danko, Wee Siang Teo, Anne M. Buboltz, Zhenhai Zhang, Qianyi Ma, Arno Oosthuysen, Abraham W. Steenkamp, Hermann Oostuisen, Philippus Venter, John Gajewski, Yu Zhang, B. Franklin Pugh, Kateryna D. Makova, Anton Nekrutenko, Elaine R. Mardis, Nick Patterson, Tom H. Pringle, Francesca Chiaromonte, James C. Mullikin, Evan E. Eichler, Ross C. Hardison, Richard A. Gibbs, Timothy T. Harkins, Vanessa M. Hayes, 2010, Nature on p. 943-947

A genome-wide analysis of common fragile sites

Arkarachai Fungtammasan, Erin Walsh, Francesca Chiaromonte, Kristin A. Eckert, Kateryna D. Makova, 2012, Genome research on p. 993-1005

Envelope models for parsimonious and efficient multivariate linear regression

R. Dennis Cook, Bing Li, Francesca Chiaromonte, 2010, Statistica Sinica on p. 927-960

Computational pan-genomics

Tobias Marschall, Manja Marz, Thomas Abeel, Louis Dijkstra, Bas E. Dutilh, Ali Ghaffaari, Paul Kersey, Wigard P. Kloosterman, Veli Mäkinen, Adam M. Novak, Benedict Paten, David Porubsky, Eric Rivals, Can Alkan, Jasmijn A. Baaijens, Paul I.W. De Bakker, Valentina Boeva, Raoul J.P. Bonnal, Francesca Chiaromonte, Rayan Chikhi, Francesca D. Ciccarelli, Robin Cijvat, Erwin Datema, Cornelia M. Van Duijn, Evan E. Eichler, Corinna Ernst, Eleazar Eskin, Erik Garrison, Mohammed El-Kebir, Gunnar W. Klau, Jan O. Korbel, Eric Wubbo Lameijer, Benjamin Langmead, Marcel Martin, Paul Medvedev, John C. Mu, Pieter Neerincx, Klaasjan Ouwens, Pierre Peterlongo, Nadia Pisanti, Sven Rahmann, Ben Raphael, Knut Reinert, Dick de Ridder, Jeroen de Ridder, Matthias Schlesner, Ole Schulz-Trieglaff, Ashley D. Sanders, Siavash Sheikhizadeh, Carl Shneider, 2018, Briefings in bioinformatics on p. 118-135

What is a microsatellite

Yogeshwar D. Kelkar, Noelle Strubczewski, Suzanne E. Hile, Francesca Chiaromonte, Kristin A. Eckert, Kateryna D. Makova, 2010, Genome biology and evolution on p. 620-635

A matter of life or death

Yogeshwar D. Kelkar, Kristin A. Eckert, Francesca Chiaromonte, Kateryna D. Makova, 2011, Genome research on p. 2038-2048

Distinct mutational behaviors differentiate short tandem repeats from micro satellites in the human genome

Guruprasad Ananda, Erin Walsh, Kimberly D. Jacob, Maria Krasilnikova, Kristin A. Eckert, Francesca Chiaromonte, Kateryna D. Makova, 2013, Genome biology and evolution on p. 606-620

A general theory for nonlinear sufficient dimension reduction

Kuang Yao Lee, Bing Li, Francesca Chiaromonte, 2013, Annals of Statistics on p. 221-249

Rescuing Alu

Bradley J. Wagstaff, Dale J. Hedges, Rebecca S. Derbes, Rebeca Campos Sanchez, Francesca Chiaromonte, Kateryna D. Makova, Astrid M. Roy-Engel, 2012, PLoS genetics

A genome-wide view of mutation rate co-variation using multivariate analyses

Guruprasad Ananda, Francesca Chiaromonte, Kateryna Dmytrivna Makova, 2011, Genome biology

News Articles Featuring Francesca Chiaromonte

Hurricanes Wreak Greater Havoc as Temperatures Soar

Devastation caused by the most powerful hurricanes has increased by up to twentyfold, according to a newly-identified pattern in natural disasters.

Cost of natural disasters like hurricanes Katrina, Maria are increasing at high end

According to an international team of researchers, The costs of major disasters like hurricanes Katrina, Maria and Dorian or the massive tornado swarms in the Midwest have increased to a disproportionately larger extent than those of lesser events, and these major disasters have become far more expensive.

Data scientists put a staggering price tag on climate change's effects

Hurricanes, floods, and other natural disasters can destroy and displace communities. Beyond the human cost, this damage is unimaginably expensive for many who are affected. New research out Monday puts a price tag on how bad things might get.

Costs of natural disasters are increasing at the high end

While the economic cost of natural disasters has not increased much on average, averages can be deceptive. The costs of major disasters like hurricanes Katrina, Maria and Dorian or the massive tornado swarms in the Midwest have increased to a disproportionately larger extent than those of lesser events, and these major disasters have become far more expensive, according to an international team of researchers.

Francesca Chiaromonte named Huck Chair in Statistics for the Life Sciences

Francesca Chiaromonte, professor of statistics at Penn State, was recently named Lloyd and Dorothy Foehr Huck Chair in Statistics by the University’s Huck Institutes of the Life Sciences.