Elizabeth McGraw
Professor and Huck Scholar in Entomology

-
W251 Millennium Science Complex
University Park, PA - She/Her
- eam7@psu.edu
- 814-865-1740
Research Summary
The genetics of vector, pathogen and symbiont interactions.
Huck Affiliations
- Center for Infectious Disease Dynamics
- Molecular, Cellular, and Integrative Biosciences
- One Health Microbiome Center
Links
Publication Tags
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Culicidae Wolbachia Aedes Aedes Aegypti Infection Dengue Virus Genes Infections Viruses Genome Gene Expression Dengue Temperature Virus Diseases Methylation Cytosine Chikungunya Virus Mosquito Pathogens Insecta Viral Load Methodology Heat Shock Response Alpha Mannosidase Specific GravityMost Recent Publications
Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures
Mario Novelo, Heverton Lc Dutra, Hillery C. Metz, Matthew J. Jones, Leah T. Sigle, Francesca D. Frentiu, Scott L. Allen, Stephen F. Chenoweth, Elizabeth A. McGraw, 2023, PLoS Pathogens on p. e1011307
Assessing the role of family level variation and heat shock gene expression in the thermal stress response of the mosquito Aedes aegypti
Fhallon Ware-Gilmore, Mario Novelo, Carla M. Sgrò, Matthew D. Hall, Elizabeth A. McGraw, 2023, Philosophical Transactions of the Royal Society B: Biological Sciences
Cross-tissue and generation predictability of relative Wolbachia densities in the mosquito Aedes aegypti
Austin J. Mejia, H. L.C. Dutra, M. J. Jones, R. Perera, E. A. McGraw, 2022, Parasites and Vectors
Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities
A. J. Mejia, L. Jimenez, H. L.C. Dutra, R. Perera, E. A. McGraw, 2022, Heredity on p. 215-224
Assessing Aedes aegypti candidate genes during viral infection and Wolbachia-mediated pathogen blocking
Leah T. Sigle, Matthew Jones, Mario Novelo, Suzanne A. Ford, Nadya Urakova, Konstantinos Lymperopoulos, Richard T. Sayre, Zhiyong Xi, Jason L. Rasgon, Elizabeth A. McGraw, 2022, Insect Molecular Biology on p. 356-368
Predicting the response of disease vectors to global change: The importance of allometric scaling
Louise S. Nørgaard, Mariana Álvarez-Noriega, Elizabeth McGraw, Craig R. White, Dustin J. Marshall, 2022, Global Change Biology on p. 390-402
The effects of DENV serotype competition and co-infection on viral kinetics in Wolbachia-infected and uninfected Aedes aegypti mosquitoes
M. Novelo, M. D. Audsley, E. A. McGraw, 2021, Parasites and Vectors
Microbes increase thermal sensitivity in the mosquito aedes aegypti, with the potential to change disease distributions
Fhallon Ware-Gilmore, Carla M. Sgrò, Zhiyong Xi, Heverton L.C. Dutra, Matthew J. Jones, Katriona Shea, Matthew D. Hall, Matthew B. Thomas, Elizabeth A. McGraw, 2021, PLoS Neglected Tropical Diseases
Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate
Devanshi Patel, Cassandra Field, Kayla Septer, Derek G. Sim, Matthew J. Jones, T Heinly, Thomas Vanderford, Elizabeth A. McGraw, Troy Sutton, 2021, Journal of Virology on p. e0223220
Temperature modulates immune gene expression in mosquitoes during arbovirus infection: Temperature, mosquitoes and arboviruses
B. M.C.Randika Wimalasiri-Yapa, Roberto A. Barrero, Liesel Stassen, Louise M. Hafner, Elizabeth A. McGraw, Alyssa T. Pyke, Cassie C. Jansen, Andreas Suhrbier, Laith Yakob, Wenbiao Hu, Gregor J. Devine, Francesca D. Frentiu, 2021, Open Biology
Most-Cited Papers
Beyond insecticides: New thinking on an ancient problem
Elizabeth McGraw, Scott O'Neill, 2013, Nature Reviews Microbiology on p. 181-193
Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia
Francesca D. Frentiu, Tasnim Zakir, Thomas Walker, Jean Popovici, Alyssa T. Pyke, Andrew van den Hurk, Elizabeth A. McGraw, Scott L. O'Neill, 2014, PLoS Neglected Tropical Diseases
Dietary Cholesterol Modulates Pathogen Blocking by Wolbachia
Eric P. Caragata, Edwige Rancès, Lauren M. Hedges, Alexander W. Gofton, Karyn N. Johnson, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS Pathogens
Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti
Neil M. Ferguson, Duong Thi Hue Kien, Hannah Clapham, Ricardo Aguas, Vu Tuan Trung, Tran Nguyen Bich Chau, Jean Popovici, Peter A. Ryan, Scott L. O'Neill, Elizabeth A. McGraw, Vo Thi Long, Le Thi Dui, Hoa L. Nguyen, Nguyen Vinh Van Chau, Bridget Wills, Cameron P. Simmons, 2015, Science Translational Medicine
Competition for Amino Acids Between Wolbachia and the Mosquito Host, Aedes aegypti
Eric P. Caragata, Edwige Rancès, Scott L. O'Neill, Elizabeth A. McGraw, 2014, Microbial Ecology on p. 205-218
Wolbachia-Associated Bacterial Protection in the Mosquito Aedes aegypti
Yixin H. Ye, Megan Woolfit, Edwige Rancès, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS Neglected Tropical Diseases
Wolbachia reduces the transmission potential of dengue-infected Aedes aegypti
Yixin H. Ye, Alison M. Carrasco, Francesca D. Frentiu, Stephen F. Chenoweth, Nigel W. Beebe, Andrew F. van den Hurk, Cameron P. Simmons, Scott L. O’Neill, Elizabeth A. McGraw, 2015, PLoS Neglected Tropical Diseases
Assessing the epidemiological effect of wolbachia for dengue control
Louis Lambrechts, Neil M. Ferguson, Eva Harris, Edward C. Holmes, Elizabeth A. McGraw, Scott L. O'Neill, Eng E. Ooi, Scott A. Ritchie, Peter A. Ryan, Thomas W. Scott, Cameron P. Simmons, Scott C. Weaver, 2015, The Lancet Infectious Diseases on p. 862-866
Infection with a Virulent Strain of Wolbachia Disrupts Genome Wide-Patterns of Cytosine Methylation in the Mosquito Aedes aegypti
Yixin H. Ye, Megan Woolfit, Gavin A. Huttley, Edwige Rancès, Eric P. Caragata, Jean Popovici, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS One
Genomic evolution of the pathogenic Wolbachia strain, wMelPop
Megan Woolfit, Iñaki Iturbe-Ormaetxe, Jeremy C. Brownlie, Thomas Walker, Markus Riegler, Andrei Seleznev, Jean Popovici, Edwige Rancès, Bryan A. Wee, Jennifer Pavlides, Mitchell J. Sullivan, Scott A. Beatson, Amanda Lane, Manpreet Sidhu, Conor J. McMeniman, Elizabeth A. McGraw, Scott L. O'Neill, 2013, Genome Biology and Evolution on p. 2189-2204
News Articles Featuring Elizabeth McGraw
Feb 23, 2023
McGraw elected as a Fellow of the American Academy of Microbiology
Elizabeth "Beth" McGraw, professor and department head of biology and Huck Scholar in Entomology at Penn State, has been elected as a Fellow of the American Academy of Microbiology.
Full Article
Feb 21, 2023
Kwapis appointed Paul Berg Early Career Professor in the Biological Sciences
Janine Kwapis, assistant professor of biology at Penn State, has been appointed as the first Paul Berg Early Career Professor in the Biological Sciences in recognition of her research contributions, teaching, and service to the Department of Biology and the Eberly College of Science.
Full Article
Nov 11, 2022
Penn State community grieves loss of biomathematician Howard Weiss
Howard Weiss, professor of biology and mathematics at Penn State, passed away peacefully in his sleep on Nov. 5 at the age of 64.
Full Article
Jul 28, 2021
Global warming may slow the spread of dengue fever
Dengue fever is a potentially lethal disease of humans that is caused by a virus transmitted in the saliva of certain mosquitoes. Recent studies led by Penn State researchers have found that mosquitoes of the species Aedes aegypti that are infected with dengue virus are less tolerant of the higher temperatures associated with global warming.
Full Article
Jul 22, 2021
Mosquitoes that carry dengue might not survive rising temperatures
Disease-carrying mosquitoes are expected to venture into new territory due to climate change and urbanization, but new research suggests that higher temperatures may curb the spread of at least one infection: dengue fever.
Full Article
Jul 22, 2021
Global warming may limit spread of dengue fever, new research finds
Infection with dengue virus makes mosquitoes more sensitive to warmer temperatures, according to new research led by Penn State researchers. The team also found that infection with the bacterium Wolbachia, which has recently been used to control viral infections in mosquitoes, also increases the thermal sensitivity of the insects.
Full Article
Feb 26, 2021
Elizabeth McGraw named head of Department of Biology
Elizabeth McGraw, professor and Huck Scholar in Entomology and director of the Center for Infectious Disease Dynamics (CIDD) at Penn State, has been named the new head of the Department of Biology.
Full Article
Feb 23, 2021
COVID vaccine questions to be answered on WPSU’s ‘Conversations Live’ on Feb. 25
Central Pennsylvanians can have their COVID-19 vaccine questions answered live during the next broadcast of WPSU’s “Conversations Live” at 8 p.m. on Thursday, Feb. 25.
Full Article
Feb 06, 2021
Masks, distancing, demography: The mystery behind India's declining Covid cases
On September 16 last year, India reported a record 97,894 coronavirus cases. Nearly four-and-half months later, on Feb 2, India registered 8,635 new cases.
Full Article
Feb 01, 2021
The Mystery Of India's Plummeting COVID-19 Cases
Last September, India was confirming nearly 100,000 new coronavirus cases a day. It was on track to overtake the United States to become the country with the highest reported COVID-19 caseload in the world. Hospitals were full. The Indian economy nosedived into an unprecedented recession.
Full Article