Elizabeth McGraw

Professor and Huck Scholar in Entomology

Elizabeth McGraw

Research Summary

The genetics of vector, pathogen and symbiont interactions.

Huck Affiliations

Links

Publication Tags

Wolbachia Culicidae Aedes Viruses Dengue Virus Infection Aedes Aegypti Infections Dengue Genome Temperature Genes Lipid Metabolism Virus Diseases Mosquito Pathogens Gene Expression Insecta Specific Gravity Global Change Ferrets Genomics Kinetics Alpha Mannosidase Methodology

Most Recent Publications

Cross-tissue and generation predictability of relative Wolbachia densities in the mosquito Aedes aegypti

Austin J. Mejia, H. L.C. Dutra, M. J. Jones, R. Perera, E. A. McGraw, 2022, Parasites and Vectors

Attempts to use breeding approaches in Aedes aegypti to create lines with distinct and stable relative Wolbachia densities

A. J. Mejia, L. Jimenez, H. L.C. Dutra, R. Perera, E. A. McGraw, 2022, Heredity on p. 215-224

Assessing Aedes aegypti candidate genes during viral infection and Wolbachia-mediated pathogen blocking

Leah T. Sigle, Matthew Jones, Mario Novelo, Suzanne A. Ford, Nadya Urakova, Konstantinos Lymperopoulos, Richard T. Sayre, Zhiyong Xi, Jason L. Rasgon, Elizabeth A. McGraw, 2022, Insect Molecular Biology on p. 356-368

Predicting the response of disease vectors to global change: The importance of allometric scaling

Louise S. Nørgaard, Mariana Álvarez-Noriega, Elizabeth McGraw, Craig R. White, Dustin J. Marshall, 2022, Global Change Biology on p. 390-402

The effects of DENV serotype competition and co-infection on viral kinetics in Wolbachia-infected and uninfected Aedes aegypti mosquitoes

M. Novelo, M. D. Audsley, E. A. McGraw, 2021, Parasites and Vectors

Microbes increase thermal sensitivity in the mosquito aedes aegypti, with the potential to change disease distributions

Fhallon Ware-Gilmore, Carla M. Sgrò, Zhiyong Xi, Heverton L.C. Dutra, Matthew J. Jones, Katriona Shea, Matthew D. Hall, Matthew B. Thomas, Elizabeth A. McGraw, 2021, PLoS Neglected Tropical Diseases

Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate

Devanshi Patel, Cassandra Field, Kayla Septer, Derek G. Sim, Matthew J. Jones, Talia A. Heinly, Thomas Vanderford, Elizabeth A. McGraw, Troy C. Sutton, 2021, Journal of Virology on p. 14

The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO

Heverton Dutra, Suzanne Ford, Scott Allen, Sarah Bordenstein, Stephen Chenoweth, Seth Bordenstein, Elizabeth A. McGraw, 2021, PLoS Neglected Tropical Diseases on p. e0009637

Temperature modulates immune gene expression in mosquitoes during arbovirus infection: Temperature, mosquitoes and arboviruses

B. M.C.Randika Wimalasiri-Yapa, Roberto A. Barrero, Liesel Stassen, Louise M. Hafner, Elizabeth A. McGraw, Alyssa T. Pyke, Cassie C. Jansen, Andreas Suhrbier, Laith Yakob, Wenbiao Hu, Gregor J. Devine, Francesca D. Frentiu, 2021, Open Biology

Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti

Cassandra Koh, M. Nurul Islam, Yixin H. Ye, Nunya Chotiwan, Barbara Graham, John T. Belisle, Konstantinos A. Kouremenos, Saravanan Dayalan, Dedreia L. Tull, Stephan Klatt, Rushika Perera, Elizabeth A. McGraw, 2020, Communications Biology

Most-Cited Papers

Beyond insecticides: New thinking on an ancient problem

Elizabeth McGraw, Scott O'Neill, 2013, Nature Reviews Microbiology on p. 181-193

Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia

Francesca D. Frentiu, Tasnim Zakir, Thomas Walker, Jean Popovici, Alyssa T. Pyke, Andrew van den Hurk, Elizabeth A. McGraw, Scott L. O'Neill, 2014, PLoS Neglected Tropical Diseases

Dietary Cholesterol Modulates Pathogen Blocking by Wolbachia

Eric P. Caragata, Edwige Rancès, Lauren M. Hedges, Alexander W. Gofton, Karyn N. Johnson, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS Pathogens

Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti

Neil M. Ferguson, Duong Thi Hue Kien, Hannah Clapham, Ricardo Aguas, Vu Tuan Trung, Tran Nguyen Bich Chau, Jean Popovici, Peter A. Ryan, Scott L. O'Neill, Elizabeth A. McGraw, Vo Thi Long, Le Thi Dui, Hoa L. Nguyen, Nguyen Vinh Van Chau, Bridget Wills, Cameron P. Simmons, 2015, Science Translational Medicine

Wolbachia reduces the transmission potential of dengue-infected Aedes aegypti

Yixin H. Ye, Alison M. Carrasco, Francesca D. Frentiu, Stephen F. Chenoweth, Nigel W. Beebe, Andrew F. van den Hurk, Cameron P. Simmons, Scott L. O’Neill, Elizabeth A. McGraw, 2015, PLoS Neglected Tropical Diseases

Wolbachia-Associated Bacterial Protection in the Mosquito Aedes aegypti

Yixin H. Ye, Megan Woolfit, Edwige Rancès, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS Neglected Tropical Diseases

Competition for Amino Acids Between Wolbachia and the Mosquito Host, Aedes aegypti

Eric P. Caragata, Edwige Rancès, Scott L. O'Neill, Elizabeth A. McGraw, 2014, Microbial Ecology on p. 205-218

Genomic evolution of the pathogenic Wolbachia strain, wMelPop

Megan Woolfit, Iñaki Iturbe-Ormaetxe, Jeremy C. Brownlie, Thomas Walker, Markus Riegler, Andrei Seleznev, Jean Popovici, Edwige Rancès, Bryan A. Wee, Jennifer Pavlides, Mitchell J. Sullivan, Scott A. Beatson, Amanda Lane, Manpreet Sidhu, Conor J. McMeniman, Elizabeth A. McGraw, Scott L. O'Neill, 2013, Genome Biology and Evolution on p. 2189-2204

Assessing the epidemiological effect of wolbachia for dengue control

Louis Lambrechts, Neil M. Ferguson, Eva Harris, Edward C. Holmes, Elizabeth A. McGraw, Scott L. O'Neill, Eng E. Ooi, Scott A. Ritchie, Peter A. Ryan, Thomas W. Scott, Cameron P. Simmons, Scott C. Weaver, 2015, The Lancet Infectious Diseases on p. 862-866

Draft genome sequence of the male-killing Wolbachia strain wBol1 reveals recent horizontal gene transfers from diverse sources

Anne Duplouy, Iñaki Iturbe-Ormaetxe, Scott A. Beatson, Jan M. Szubert, Jeremy C. Brownlie, Conor J. McMeniman, Elizabeth A. McGraw, Gregory D.D. Hurst, Sylvain Charlat, Scott L. O'Neill, Megan Woolfit, 2013, BMC Genomics

News Articles Featuring Elizabeth McGraw

Nov 11, 2022

Penn State community grieves loss of biomathematician Howard Weiss

Howard Weiss, professor of biology and mathematics at Penn State, passed away peacefully in his sleep on Nov. 5 at the age of 64.

Full Article

Jul 28, 2021

Global warming may slow the spread of dengue fever

Dengue fever is a potentially lethal disease of humans that is caused by a virus transmitted in the saliva of certain mosquitoes. Recent studies led by Penn State researchers have found that mosquitoes of the species Aedes aegypti that are infected with dengue virus are less tolerant of the higher temperatures associated with global warming.

Full Article

Jul 22, 2021

Mosquitoes that carry dengue might not survive rising temperatures

Disease-carrying mosquitoes are expected to venture into new territory due to climate change and urbanization, but new research suggests that higher temperatures may curb the spread of at least one infection: dengue fever.

Full Article

Jul 22, 2021

Global warming may limit spread of dengue fever, new research finds

Infection with dengue virus makes mosquitoes more sensitive to warmer temperatures, according to new research led by Penn State researchers. The team also found that infection with the bacterium Wolbachia, which has recently been used to control viral infections in mosquitoes, also increases the thermal sensitivity of the insects.

Full Article

Feb 26, 2021

Elizabeth McGraw named head of Department of Biology

Elizabeth McGraw, professor and Huck Scholar in Entomology and director of the Center for Infectious Disease Dynamics (CIDD) at Penn State, has been named the new head of the Department of Biology.

Full Article

Feb 23, 2021

COVID vaccine questions to be answered on WPSU’s ‘Conversations Live’ on Feb. 25

Central Pennsylvanians can have their COVID-19 vaccine questions answered live during the next broadcast of WPSU’s “Conversations Live” at 8 p.m. on Thursday, Feb. 25.

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Feb 06, 2021

Masks, distancing, demography: The mystery behind India's declining Covid cases

On September 16 last year, India reported a record 97,894 coronavirus cases. Nearly four-and-half months later, on Feb 2, India registered 8,635 new cases.

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Feb 01, 2021

The Mystery Of India's Plummeting COVID-19 Cases

Last September, India was confirming nearly 100,000 new coronavirus cases a day. It was on track to overtake the United States to become the country with the highest reported COVID-19 caseload in the world. Hospitals were full. The Indian economy nosedived into an unprecedented recession.

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Nov 30, 2020

Sorry to Burst Your Quarantine Bubble

Pod means something different to everyone, and that’s a problem.

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Nov 18, 2020

Will There Be Black Friday Shipping Delays? Prepare To Be Patient

Black Friday is getting closer and closer, and as much as everyone loves a good deal, the influx in people shopping online, given the ongoing coronavirus pandemic, is something to be mindful of. If you remember the beginning of the pandemic, when nearly everyone went on an online shopping bender in a flurry of panic, you'll also remember the serious shipping delays and health concerns for those working in fulfillment and delivery centers. Now that it's almost time for holiday shopping, the question on everyone's mind is: Will there be Black Friday shipping delays?

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