Elizabeth McGraw

Professor and Huck Scholar in Entomology

Elizabeth McGraw

Research Summary

The genetics of vector, pathogen and symbiont interactions.

Huck Affiliations


Publication Tags

Wolbachia Culicidae Aedes Dengue Viruses Dengue Virus Infection Infections Lipid Metabolism Temperature Genome Aedes Aegypti Genes Population Gene Expression Insecta Antiviral Agents Ferrets Malaysia Genomics Muscidae Cell Lines Public Health Virus Diseases Methodology

Most Recent Papers

Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate

Devanshi R. Patel, Cassandra J. Field, Kayla M. Septer, Derek G. Sim, Matthew J. Jones, Talia A. Heinly, Thomas H. Vanderford, Elizabeth A. McGraw, Troy C. Sutton, 2021, Journal of Virology

Temperature modulates immune gene expression in mosquitoes during arbovirus infection

B. M.C.Randika Wimalasiri-Yapa, Roberto A. Barrero, Liesel Stassen, Louise M. Hafner, Elizabeth A. McGraw, Alyssa T. Pyke, Cassie C. Jansen, Andreas Suhrbier, Laith Yakob, Wenbiao Hu, Gregor J. Devine, Francesca D. Frentiu, 2021, Open Biology

Dengue virus dominates lipid metabolism modulations in Wolbachia-coinfected Aedes aegypti

Cassandra Koh, M. Nurul Islam, Yixin H. Ye, Nunya Chotiwan, Barbara Graham, John T. Belisle, Konstantinos A. Kouremenos, Saravanan Dayalan, Dedreia L. Tull, Stephan Klatt, Rushika Perera, Elizabeth A. McGraw, 2020, Communications Biology

Artificial Selection Finds New Hypotheses for the Mechanism of Wolbachia-Mediated Dengue Blocking in Mosquitoes

Suzanne A. Ford, Istvan Albert, Scott L. Allen, Stephen F. Chenoweth, Matthew Jones, Cassandra Koh, Aswathy Sebastian, Leah T. Sigle, Elizabeth A. McGraw, 2020, Frontiers in Microbiology

Wolbachia successfully replicate in a newly established horn fly, Haematobia irritans irritans (L.) (Diptera

Mukund Madhav, Geoff Brown, Jess A.T. Morgan, Sassan Asgari, Elizabeth A. McGraw, Ulrike G. Munderloh, Timothy J. Kurtti, Peter James, 2020, Pest Management Science on p. 2441-2452

Transinfection of buffalo flies (Haematobia irritans exigua) with Wolbachia and effect on host biology

Mukund Madhav, Geoff Brown, Jess A.T. Morgan, Sassan Asgari, Elizabeth A. McGraw, Peter James, 2020, Parasites and Vectors

Infectious Diseases

Ewa Chrostek, Gregory D.D. Hurst, Elizabeth A. McGraw, 2020, Current Biology on p. R30-R32

Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness

Suzanne A. Ford, Scott L. Allen, Johanna R. Ohm, Leah T. Sigle, Aswathy Sebastian, Istvan Albert, Stephen F. Chenoweth, Elizabeth A. McGraw, 2019, Nature Microbiology on p. 1832-1839

Chikungunya virus transmission at low temperature by aedes albopictus mosquitoes

B. M.C.Randika Wimalasiri-Yapa, Liesel Stassen, Wenbiao Hu, Laith Yakob, Elizabeth A. McGraw, Alyssa T. Pyke, Cassie C. Jansen, Gregor J. Devine, Francesca D. Frentiu, 2019, Pathogens

Using genetic variation in Aedes aegypti to identify candidate anti-dengue virus genes

Gerard Terradas, Elizabeth A. McGraw, 2019, BMC Infectious Diseases

Most-Cited Papers

Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission

A. A. Hoffmann, B. L. Montgomery, J. Popovici, I. Iturbe-Ormaetxe, P. H. Johnson, F. Muzzi, M. Greenfield, M. Durkan, Y. S. Leong, Y. Dong, H. Cook, J. Axford, A. G. Callahan, N. Kenny, C. Omodei, E. A. McGraw, P. A. Ryan, S. A. Ritchie, M. Turelli, S. L. O'Neill, 2011, Nature on p. 454-459

Beyond insecticides

Elizabeth A. McGraw, Scott L. O'Neill, 2013, Nature Reviews Microbiology on p. 181-193

Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia

Francesca D. Frentiu, Tasnim Zakir, Thomas Walker, Jean Popovici, Alyssa T. Pyke, Andrew van den Hurk, Elizabeth A. McGraw, Scott L. O'Neill, 2014, PLoS Neglected Tropical Diseases

The relative importance of innate immune priming in Wolbachia-mediated dengue interference

Edwige Rancès, Yixin H. Ye, Megan Woolfit, Elizabeth A. McGraw, Scott L. O'Neill, 2012, PLoS Pathogens

Dietary Cholesterol Modulates Pathogen Blocking by Wolbachia

Eric P. Caragata, Edwige Rancès, Lauren M. Hedges, Alexander W. Gofton, Karyn N. Johnson, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS Pathogens

Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti

Neil M. Ferguson, Duong Thi Hue Kien, Hannah Clapham, Ricardo Aguas, Vu Tuan Trung, Tran Nguyen Bich Chau, Jean Popovici, Peter A. Ryan, Scott L. O'Neill, Elizabeth A. McGraw, Vo Thi Long, Le Thi Dui, Hoa L. Nguyen, Nguyen Vinh Van Chau, Bridget Wills, Cameron P. Simmons, 2015, Science Translational Medicine

Wolbachia reduces the transmission potential of dengue-infected Aedes aegypti

Yixin H. Ye, Alison M. Carrasco, Francesca D. Frentiu, Stephen F. Chenoweth, Nigel W. Beebe, Andrew F. van den Hurk, Cameron P. Simmons, Scott L. O’Neill, Elizabeth A. McGraw, 2015, PLoS Neglected Tropical Diseases

Wolbachia-Associated Bacterial Protection in the Mosquito Aedes aegypti

Yixin H. Ye, Megan Woolfit, Edwige Rancès, Scott L. O'Neill, Elizabeth A. McGraw, 2013, PLoS Neglected Tropical Diseases

Competition for Amino Acids Between Wolbachia and the Mosquito Host, Aedes aegypti

Eric P. Caragata, Edwige Rancès, Scott L. O'Neill, Elizabeth A. McGraw, 2014, Microbial Ecology on p. 205-218

Genomic evolution of the pathogenic Wolbachia strain, wMelPop

Megan Woolfit, Iñaki Iturbe-Ormaetxe, Jeremy C. Brownlie, Thomas Walker, Markus Riegler, Andrei Seleznev, Jean Popovici, Edwige Rancès, Bryan A. Wee, Jennifer Pavlides, Mitchell J. Sullivan, Scott A. Beatson, Amanda Lane, Manpreet Sidhu, Conor J. McMeniman, Elizabeth A. McGraw, Scott L. O'Neill, 2013, Genome Biology and Evolution on p. 2189-2204

News Articles Featuring Elizabeth McGraw

Global warming may slow the spread of dengue fever

Dengue fever is a potentially lethal disease of humans that is caused by a virus transmitted in the saliva of certain mosquitoes. Recent studies led by Penn State researchers have found that mosquitoes of the species Aedes aegypti that are infected with dengue virus are less tolerant of the higher temperatures associated with global warming.

Mosquitoes that carry dengue might not survive rising temperatures

Disease-carrying mosquitoes are expected to venture into new territory due to climate change and urbanization, but new research suggests that higher temperatures may curb the spread of at least one infection: dengue fever.

Global warming may limit spread of dengue fever, new research finds

Infection with dengue virus makes mosquitoes more sensitive to warmer temperatures, according to new research led by Penn State researchers. The team also found that infection with the bacterium Wolbachia, which has recently been used to control viral infections in mosquitoes, also increases the thermal sensitivity of the insects.

Elizabeth McGraw named head of Department of Biology

Elizabeth McGraw, professor and Huck Scholar in Entomology and director of the Center for Infectious Disease Dynamics (CIDD) at Penn State, has been named the new head of the Department of Biology.

COVID vaccine questions to be answered on WPSU’s ‘Conversations Live’ on Feb. 25

Central Pennsylvanians can have their COVID-19 vaccine questions answered live during the next broadcast of WPSU’s “Conversations Live” at 8 p.m. on Thursday, Feb. 25.

Masks, distancing, demography: The mystery behind India's declining Covid cases

On September 16 last year, India reported a record 97,894 coronavirus cases. Nearly four-and-half months later, on Feb 2, India registered 8,635 new cases.

The Mystery Of India's Plummeting COVID-19 Cases

Last September, India was confirming nearly 100,000 new coronavirus cases a day. It was on track to overtake the United States to become the country with the highest reported COVID-19 caseload in the world. Hospitals were full. The Indian economy nosedived into an unprecedented recession.

Sorry to Burst Your Quarantine Bubble

Pod means something different to everyone, and that’s a problem.

Will There Be Black Friday Shipping Delays? Prepare To Be Patient

Black Friday is getting closer and closer, and as much as everyone loves a good deal, the influx in people shopping online, given the ongoing coronavirus pandemic, is something to be mindful of. If you remember the beginning of the pandemic, when nearly everyone went on an online shopping bender in a flurry of panic, you'll also remember the serious shipping delays and health concerns for those working in fulfillment and delivery centers. Now that it's almost time for holiday shopping, the question on everyone's mind is: Will there be Black Friday shipping delays?

State not releasing detailed COVID outbreak data

As Indiana sees its number of COVID-19 cases surge, some Hoosiers might be wondering where the biggest outbreaks are happening. A busy party center in the suburbs? A business conference center downtown? Gyms, bars and restaurants in the hippest neighborhoods?