Dhimant Desai

Associate Professor of Pharmacology

Dhimant Desai

Publication Tags

Neoplasms Selenium P Glycoprotein Therapeutics Ceramides Histone Deacetylase Inhibitors Sulforafan Chemoprevention Glycine Viruses Dna Adducts Vorinostat Proteins Muricholic Acid Cells Intestines Genes Pharmacology Skin Glutathione Aryl Hydrocarbon Receptors Tobacco Obesity Casein Kinase Ii N' Nitrosonornicotine

Most Recent Papers

Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

Yali Ding, Bo Zhang, Jonathon L. Payne, Chunhua Song, Zheng Ge, Chandrika Gowda, Soumya Iyer, Pavan K. Dhanyamraju, Glenn Dorsam, Mark E. Reeves, Dhimant Desai, Suming Huang, Kimberly J. Payne, Feng Yue, Sinisa Dovat, 2019, Leukemia on p. 2720-2731

Effects of the Tobacco Carcinogens N′-Nitrosonornicotine and Dibenzo[ a, l]pyrene Individually and in Combination on DNA Damage in Human Oral Leukoplakia and on Mutagenicity and Mutation Profiles in lacI Mouse Tongue

Joseph B. Guttenplan, Kun-Ming Chen, Yuan-Wan Sun, Nora A.E. Shalaby, Wieslawa Kosinska, Dhimant Desai, Krishne Gowda, Shantu Amin, Karam El-Bayoumy, 2019, Chemical research in toxicology on p. 1893-1899

Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors

Dhimant Desai, Matthew Lauver, Alexandria Ostman, Linda Cruz, Kevin Ferguson, Ge Jin, Brianne Roper, Daniel Brosius, Aron Lukacher, Shantu Amin, Nicholas Buchkovich, 2019, Bioorganic and Medicinal Chemistry on p. 1795-1803

Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers

Emily M. Nakada, Nirav R. Bhakta, Bethany R. Korwin-Mihavics, Amit Kumar, Nicolas Chamberlain, Sierra R. Bruno, David G. Chapman, Sidra M. Hoffman, Nirav Daphtary, Minara Aliyeva, Charles G. Irvin, Anne E. Dixon, Prescott G. Woodruff, Shantu Amin, Matthew E. Poynter, Dhimant H. Desai, Vikas Anathy, 2019, JCI Insight

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

Su Fern Tan, Wendy Dunton, Xin Liu, Todd E. Fox, Samy A.F. Morad, Dhimant Desai, Kenichiro Doi, Mark R. Conaway, Shantu Amin, David Claxton, Hong-Gang Wang, Mark Kester, Myles C. Cabot, David J. Feith, Thomas P. Loughran, 2019, Journal of Lipid Research on p. 1078-1086

Monoclonal Antibodies for the Detection of a Specific Cyclic DNA Adduct Derived from ω-6 Polyunsaturated Fatty Acids

Marcin Dyba, Brandon Da Silva, Heidi Coia, Yanqi Hou, Sumire Noguchi, Jishen Pan, Deborah Berry, Karen Creswell, Jacek Krzeminski, Dhimant Desai, Shantu Amin, David Yang, Fung Lung Chung, 2018, Chemical research in toxicology on p. 772-783

Inhibition of retrograde transport limits polyomavirus infection in vivo

Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher, 2017, mSphere

Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer

Samy A.F. Morad, Traci S. Davis, Matthew R. MacDougall, Su Fern Tan, David J. Feith, Dhimant H. Desai, Shantu G. Amin, Mark Kester, Thomas P. Loughran, Myles C. Cabot, 2017, Biochemical Pharmacology on p. 21-33

Potent inhibition of human cytomegalovirus by modulation of cellular SNARE syntaxin 5

Linda Cruz, Nicholas T. Streck, Kevin Ferguson, Trisha Desai, Dhimant H. Desai, Shantu G. Amin, Nicholas J. Buchkovich, 2017, Journal of virology

SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models

Jeremy Hengst, Taryn E. Dick, Arati Sharma, Kenichiro Doi, Shailaja Hegde, Su Fern Tan, Laura Geffert, Todd E. Fox, Arun K. Sharma, Dhimant Desai, Shantu Amin, Mark Kester, Thomas P. Loughran, Robert Paulson, David Claxton, Hong-Gang Wang, Jong Yun, 2017, Cancer Translational Medicine on p. 109-121

Most-Cited Papers

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Changtao Jiang, Cen Xie, Fei Li, Limin Zhang, Robert G. Nichols, Kristopher W. Krausz, Jingwei Cai, Yunpeng Qi, Zhong Ze Fang, Shogo Takahashi, Naoki Tanaka, Dhimant Desai, Shantu G. Amin, Istvan Albert, Andrew D. Patterson, Frank J. Gonzalez, 2015, Journal of Clinical Investigation on p. 386-402

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang, Cen Xie, Ying Lv, Jing Li, Kristopher W. Krausz, Jingmin Shi, Chad N. Brocker, Dhimant Desai, Shantu G. Amin, William H. Bisson, Yulan Liu, Oksana Gavrilova, Andrew D. Patterson, Frank J. Gonzalez, 2015, Nature communications

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat, 2015, Blood on p. 1813-1822

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4

Natalie Nguyen, Arati Sharma, Nhung Nguyen, Arun K. Sharma, Dhimant Desai, Sung Jin Huh, Shantu Amin, Craig Meyers, Gavin P. Robertson, 2011, Cancer Prevention Research on p. 248-258

Enhanced Nrf2-dependent induction of glutathione in mouse embryonic fibroblasts by isoselenocyanate analog of sulforaphane

Sans W. Emmert, Dhimant Desai, Shantu Amin, John Richie, 2010, Bioorganic and Medicinal Chemistry Letters on p. 2675-2679

Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation

Ellen H. Van Den Bogaard, Michael A. Podolsky, Jos P. Smits, Xiao Cui, Christian John, Krishne Gowda, Dhimant Desai, Shantu G. Amin, Joost Schalkwijk, Gary H. Perdew, Adam B. Glick, 2015, Journal of Investigative Dermatology on p. 1320-1328

SelSA, selenium analogs of SAHA as potent histone deacetylase inhibitors

Dhimant Desai, Ugur Salli, Kent Vrana, Shantu Amin, 2010, Bioorganic and Medicinal Chemistry Letters on p. 2044-2047

Chemoprevention of prostate cancer by D,L-sulforaphane is augmented by pharmacological inhibition of autophagy

Avani R. Vyas, Eun Ryeong Hahm, Julie A. Arlotti, Simon Watkins, Donna Beer Stolz, Dhimant Desai, Shantu Amin, Shivendra V. Singh, 2013, Cancer Research on p. 5985-5995

Crucial role of macrophage selenoproteins in experimental colitis

Naveen Kaushal, Avinash K. Kudva, Andrew D. Patterson, Christopher Chiaro, Mary J. Kennett, Dhimant Desai, Shantu Amin, Bradley A. Carlson, Margherita T. Cantorna, K. Sandeep Prabhu, 2014, Journal of Immunology on p. 3683-3692

Selenium-containing histone deacetylase inhibitors for melanoma management

Raghavendra Gowda, Subba Rao V. Madhunapantula, Dhimant Desai, Shantu Amin, Gavin P. Robertson, 2012, Cancer Biology and Therapy on p. 756-765