Dhimant Desai

Associate Professor of Pharmacology

Dhimant Desai

Huck Affiliations

Most Recent Publications

Erratum: Corrigendum] Chemopreventive effects of PBI‑Se, a selenium‑containing analog of PBIT, on AOM‑induced aberrant crypt foci in F344 rats (Oncology reports (2013) 30 2 PII: 44 DOI: 10.3892/or.2013.2483.)

Naveena B. Janakiram, Altaf Mohammed, Durgadevi Ravillah, Chang In Choi, Yuting Zhang, Dhimant Desai, Shantu Amin, Chinthalapally V. Rao, 2025, Oncology Reports

Discovering Potential in Non-Cancer Medications: A Promising Breakthrough for Multiple Myeloma Patients

Omar S. Al-Odat, Emily Nelson, Tulin Budak-Alpdogan, Subash C. Jonnalagadda, Dhimant Desai, Manoj K. Pandey, 2024, Cancers

The Potential of Cannabichromene (CBC) as a Therapeutic Agent

Diana Sepulveda, Kent Vrana, Joshua Kellogg, Jordan Bisanz, Dhimant Desai, Nicholas M. Graziane, Wesley Raup-Konsavage, 2024, Journal of Pharmacology and Experimental Therapeutics on p. 206-213

The underappreciated diversity of bile acid modifications

Ipsita Mohanty, Helena Mannochio-Russo, Joshua V. Schweer, Yasin El Abiead, Wout Bittremieux, Shipei Xing, Robin Schmid, Simone Zuffa, Felipe Vasquez, Valentina B. Muti, Jasmine Zemlin, Omar E. Tovar-Herrera, Sarah Moraïs, Dhimant Desai, Shantu Amin, Imhoi Koo, Christoph W. Turck, Itzhak Mizrahi, Penny Margaret Kris-Etherton, Kristina Petersen, Jennifer A. Fleming, Tao Huan, Andrew D. Patterson, Dionicio Siegel, Lee R. Hagey, Mingxun Wang, Allegra T. Aron, Pieter C. Dorrestein, 2024, Cell on p. 1801-1818.e20

SelSA-1, a novel HDAC inhibitor demonstrates enhanced chemotherapeutic potential by redox modulation

Ayushi Garg, Dhimant Desai, Aman Bhalla, Shalu Thakur, Pulkit Rastogi, Naveen Kaushal, 2023, Scientific Reports

Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases

Vijay Pralhad Kale, Jeremy A. Hengst, Arati K. Sharma, Upendarrao Golla, Sinisa Dovat, Shantu G. Amin, Jong K. Yun, Dhimant H. Desai, 2023, Pharmaceuticals

Complex chemical signals dictate Ah receptor activation through the gut-lung axis

Fangcong Dong, Iain A. Murray, Andrew Annalora, Denise M. Coslo, Dhimant Desai, Krishne Gowda, Jian Yang, Dingbowen Wang, Imhoi Koo, Fuhua Hao, Shantu G. Amin, Andrew D. Patterson, Craig Marcus, Gary H. Perdew, 2023, FASEB Journal on p. e23010

Signaling pathways and regulation of gene expression in hematopoietic cells

Daniel Bogush, Joseph Schramm, Yali Ding, Bing He, Chingakham Singh, Arati Sharma, Diwakar Bastihalli Tukaramrao, Soumya Iyer, Dhimant Desai, Gregory Nalesnik, Jeremy Hengst, Riya Bhalodia, Chandrika Gowda, Sinisa Dovat, 2023, Advances in Biological Regulation

Selenocoxib-3, a novel anti-inflammatory therapeutic effectively resolves colitis

Ramanpreet Kaur, Dhimant Desai, Shantu Amin, Kaisar Raza, Aman Bhalla, Pooja Yadav, Naveen Kaushal, 2023, Molecular and Cellular Biochemistry on p. 621-636

Aryl Hydrocarbon Receptor Activation Coordinates Mouse Small Intestinal Epithelial Cell Programming

Xiaoliang Zhou, Debopriya Chakraborty, Iain A. Murray, Denise Coslo, Zoe Kehs, Anitha Vijay, Carolyn Ton, Dhimant Desai, Shantu G. Amin, Andrew D. Patterson, Gary H. Perdew, 2023, Laboratory Investigation on p. 100012

Most-Cited Papers

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Changtao Jiang, Cen Xie, Fei Li, Limin Zhang, Robert G. Nichols, Kristopher W. Krausz, Jingwei Cai, Yunpeng Qi, Zhong Ze Fang, Shogo Takahashi, Naoki Tanaka, Dhimant Desai, Shantu G. Amin, Istvan Albert, Andrew D. Patterson, Frank J. Gonzalez, 2015, Journal of Clinical Investigation on p. 386-402

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang, Cen Xie, Ying Lv, Jing Li, Kristopher W. Krausz, Jingmin Shi, Chad N. Brocker, Dhimant Desai, Shantu G. Amin, William H. Bisson, Yulan Liu, Oksana Gavrilova, Andrew D. Patterson, Frank J. Gonzalez, 2015, Nature Communications

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat, 2015, Blood on p. 1813-1822

Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation

Ellen H. Van Den Bogaard, Michael A. Podolsky, Jos P. Smits, Xiao Cui, Christian John, Krishne Gowda, Dhimant Desai, Shantu G. Amin, Joost Schalkwijk, Gary H. Perdew, Adam B. Glick, 2015, Journal of Investigative Dermatology on p. 1320-1328

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

Su Fern Tan, Xin Liu, Todd E. Fox, Brian M. Barth, Arati Sharma, Stephen D. Turner, Andy Awwad, Alden Dewey, Kenichiro Doi, Barbara Spitzer, Mithun Vinod Shah, Samy A.F. Morad, Dhimant Desai, Shantu Amin, Junjia Zhu, Jason Liao, Jong Yun, Mark Kester, David F. Claxton, Hong Gang Wang, Myles C. Cabot, Edward H. Schuchman, Ross L. Levine, David J. Feith, Thomas P. Loughran, 2016, Oncotarget on p. 83208-83222

The underappreciated diversity of bile acid modifications

Ipsita Mohanty, Helena Mannochio-Russo, Joshua V. Schweer, Yasin El Abiead, Wout Bittremieux, Shipei Xing, Robin Schmid, Simone Zuffa, Felipe Vasquez, Valentina B. Muti, Jasmine Zemlin, Omar E. Tovar-Herrera, Sarah Moraïs, Dhimant Desai, Shantu Amin, Imhoi Koo, Christoph W. Turck, Itzhak Mizrahi, Penny Margaret Kris-Etherton, Kristina Petersen, Jennifer A. Fleming, Tao Huan, Andrew D. Patterson, Dionicio Siegel, Lee R. Hagey, Mingxun Wang, Allegra T. Aron, Pieter C. Dorrestein, 2024, Cell on p. 1801-1818.e20

Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers

Emily M. Nakada, Nirav R. Bhakta, Bethany R. Korwin-Mihavics, Amit Kumar, Nicolas Chamberlain, Sierra R. Bruno, David G. Chapman, Sidra M. Hoffman, Nirav Daphtary, Minara Aliyeva, Charles G. Irvin, Anne E. Dixon, Prescott G. Woodruff, Shantu Amin, Matthew E. Poynter, Dhimant H. Desai, Vikas Anathy, 2019, JCI insight

The regulatory roles of ROCK and MRCK kinases in the plasticity of cancer cell migration

Vijay Pralhad Kale, Jeremy A. Hengst, Dhimant H. Desai, Shantu G. Amin, Jong K. Yun, 2015, Cancer Letters on p. 185-196

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249

Mao Wen Weng, Hyun Wook Lee, Bongkun Choi, Hsiang Tsui Wang, Yu Hu, Manju Mehta, Dhimant Desai, Shantu Amin, Yi Zheng, Moon Shong Tang, 2017, Oncotarget on p. 18213-18226

IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia

Chunhua Song, Zheng Ge, Yali Ding, Bi Hua Tan, Dhimant Desai, Krishne Gowda, Shantu Amin, Raghavendra Gowda, Gavin P. Robertson, Feng Yue, Suming Huang, Vladimir Spiegelman, Jonathon L. Payne, Mark E. Reeves, Zafer Gurel, Soumya Iyer, Pavan Kumar Dhanyamraju, Meixian Xiang, Yuka Imamura Kawasawa, Nathalia M. Cury, José Andrés Yunes, Mary McGrath, Joe Schramm, Ruijun Su, Yiping Yang, Zhijun Zhao, Xiaoguang Lyu, Markus Muschen, Kimberly J. Payne, Chandrika Gowda, Sinisa Dovat, 2020, Blood on p. 1520-1534