David Kennedy

Assistant Professor of Biology

David Kennedy

Research Summary

Ecology and evolution of infectious diseases, with particular interest in how disease dynamics influence pathogen emergence, virulence evolution, and drug or vaccine resistance.

Huck Graduate Students

Huck Affiliations

Links

Publication Tags

Vaccines Pathogens Poultry Drug Resistance Clinical Trials Resistance Viruses Virulence Principal Component Analysis Aquaculture Pathogen Farms Pharmaceutical Preparations Vaccination Economics Efficacy Genetic Drift Industry Markov Chain Monte Carlo Parallel Computing Marek Disease Immune System Mardivirus Influenza A Virus Population

Most Recent Publications

Troy Day, David A. Kennedy, Andrew F. Read, David McAdams, 2021, PLoS Biology

Clara L. Shaw, David A. Kennedy, 2021, Theoretical Population Biology on p. 2-9

What you need to know about the new COVID-19 variants

David Kennedy, 2021,

The evolutionary epidemiology of pathogens during vaccination campaigns

Troy Day, David Kennedy, A Read, Sylvain Gandon, 2021, arXiv preprint arXiv:2109.13680

Why it matters that the coronavirus is changing -- and what this means for vaccine effectiveness

David Kennedy, 2020,

Virus evolution could undermine a COVID-19 vaccine -- but this can be stopped

A Read, David Kennedy, 2020,

David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology

Most-Cited Papers

Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, 2015, PLoS Biology on p. e1002198

David A. Kennedy, Andrew F. Read, 2017, Proceedings of the Royal Society B: Biological Sciences

David A. Kennedy, Gael Kurath, Ilana L. Brito, Maureen K. Purcell, Andrew F. Read, James R. Winton, Andrew R. Wargo, 2016, Evolutionary Applications on p. 344-354

David A. Kennedy, Andrew F. Read, 2018, Proceedings of the National Academy of Sciences of the United States of America on p. 12878-12886

David A. Kennedy, Andrew F. Read, David A. Kennedy, 2020, PLoS Biology

David A. Kennedy, Christopher Cairns, Matthew J. Jones, Andrew S. Bell, Rahel M. Salathé, Susan J. Baigent, Venugopal K. Nair, Patricia A. Dunn, Andrew F. Read, 2017, Avian Diseases on p. 153-164

K. M. Pepin, E. Spackman, J. D. Brown, K. L. Pabilonia, L. P. Garber, J. T. Weaver, D. A. Kennedy, K. A. Patyk, K. P. Huyvaert, R. S. Miller, A. B. Franklin, K. Pedersen, T. L. Bogich, P. Rohani, S. A. Shriner, C. T. Webb, S. Riley, 2014, Preventive Veterinary Medicine on p. 376-397

Pathogen growth in insect hosts

David A. Kennedy, Vanja Dukic, Greg Dwyer, 2014, American Naturalist on p. 407-423

Combining principal component analysis with parameter line-searches to improve the efficacy of Metropolis–Hastings MCMC

David A. Kennedy, Vanja Dukic, Greg Dwyer, 2015, Environmental and Ecological Statistics on p. 247-274

News Articles Featuring David Kennedy

Disease outcomes differ by new host species in virus spillover experiments

Why has the SARS-CoV-2 virus ravaged the global human population, but many other animal viruses haven't? Using nematode worms as a model, researchers at Penn State conducted a set of experiments to investigate the factors influencing the disease outcomes of virus spillover events.

Vaccine Makers Already Testing Their Shots Against Omicron Variant

As concerns about the new Omicron variant grow, vaccine makers say they're already working on ways to protect people against the potential new threat.

Will Covid variant omicron need a new vaccine? Time and data will tell

The discovery of another coronavirus variant has raised new concerns about the ability of existing vaccines to protect against the mutating virus — and whether they’ll need to be updated.

New tool weighs costs and benefits of managing evolution of pathogens and pests

Spend money now on antibiotic stewardship practices or save the money but run the risk of potentially deadly antibiotic-resistant bacteria emerging later? A new economic tool can help physicians, farmers and other people whose activities may influence the evolution of biological organisms, such as pathogens and insects, decide when they should invest in evolution management strategies.

Are the vaccines effective against mutant Covid variants?

India is undergoing a massive vaccination effort in the midst of a devastating rise in reported daily cases and deaths. While the main cause of the rise in cases is yet to be determined, epidemiological and virological data point to the rise of new variants of concern being a major contributing factor.

How Much Should We Really Worry About the Coronavirus Variants?

Even as things look promising for summer, the coronavirus is still finding new ways to threaten our creep back to normal and our general sense of health and safety.

How devastating could Brazil's 'super-covid' be? Study finds coronavirus overwhelmed the country, killing nearly 40% of hospitalized patients as fears grow its variant could ALREADY be in America

Nearly 40 percent of hospitalized COVID-19 patients in Brazil died of the virus as the nation's health care system was inundated with coronavirus cases last year, a new study estimates.

Why it matters that the coronavirus is changing — and what this means for vaccine effectiveness (Philadelphia Inquirer)

If this new version of the virus is here to stay, as it appears to be, what does that mean? Will this new version of the virus replace the old one? Will it be easier to catch? And, most important, will the current vaccines still be effective?

Why it matters that the coronavirus is changing — and what this means for vaccine effectiveness (The Conversation)

A new variant of SARS-CoV-2 is spreading rapidly in the United Kingdom, with over 1,400 cases since September. SARS-CoV-2, the virus that causes COVID-19, generally accumulates mutations slowly over time, but this new variant had accumulated many mutations quickly.

What happens if you skip the second dose of the COVID-19 vaccine?

As Pfizer’s COVID-19 vaccine begins circulating, there is another big logistical challenge ahead: reminding people to get the second dose.