David Gilmour
Professor of Molecular and Cell Biology

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465A Frear North
University Park, PA - dsg11@psu.edu
- 814-863-7024
Research Summary
Transcriptional regulation of the hsp70 heat shock gene in Drosophila.
Huck Affiliations
Links
Publication Tags
Rna Polymerase Ii Phosphorylation Genes Drosophila Transcription Factors Gene Expression Transcription Rna Polymerase Iii Switches Mass Spectrometry Drosophila Melanogaster Chromatin Proteins Rna Proline Negative Elongation Factor Nucleic Acid Repetitive Sequences Dephosphorylation Tata Box Binding Protein Like Proteins Nexus Ribosomal Proteins Dichlororibofuranosylbenzimidazole Consensus Heterogeneity ElongationMost Recent Publications
In silicons identification of Drosophila melanogaster genes encoding RNA polymerase subunits
Steven Marygold, Nazif Alic, David Gilmour, Savraj Grewal, microPublication Biology
Spt5-nucleic acid interactions are directly involved in promoter proximal pausing of RNA polymerase II
Roberta Dollinger, David S. Gilmour, 2022, FASEB Journal
Regulation of Promoter Proximal Pausing of RNA Polymerase II in Metazoans
Roberta Dollinger, David S. Gilmour, 2021, Journal of Molecular Biology
Genetic analysis of the RNA polymerase II CTD in Drosophila
Feiyue Lu, David S. Gilmour, 2019, ImmunoMethods on p. 129-137
The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads
Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular Cell on p. 1232-1242.e4
GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional coactivator
Douglas G. Baumann, Mu Shui Dai, Hua Lu, David S. Gilmour, 2018, Molecular and Cellular Biology
GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional co-activator.
D Baumann, M Dai, H Lu, David Gilmour, 2017, Molecular and cellular biology
A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes
Douglas G. Baumann, David S. Gilmour, 2017, Nucleic Acids Research on p. 10481-10491
Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain
Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature Communications
Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain
Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature Communications
Most-Cited Papers
XPaused Pol II coordinates tissue morphogenesis in the drosophila embryo
Mounia Lagha, Jacques P. Bothma, Emilia Esposito, Samuel Ng, Laura Stefanik, Chiahao Tsui, Jeffrey Johnston, Kai Chen, David S. Gilmour, Julia Zeitlinger, Michael S. Levine, 2013, Cell
Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor
Jian Li, David S. Gilmour, 2013, EMBO Journal on p. 1829-1841
Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing
Jian Li, Yingyun Liu, Ho Sung Rhee, Saikat Kumar B. Ghosh, Lu Bai, B. Franklin Pugh, David S. Gilmour, 2013, Molecular Cell on p. 711-722
Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain
Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature Communications
Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription
Malini Natarajan, Gillian M. Schiralli Lester, Chanhyo Lee, Anamika Missra, Gregory A. Wasserman, Martin Steffen, David S. Gilmour, Andrew J. Henderson, 2013, Journal of Biological Chemistry on p. 25995-26003
Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain
Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature Communications
The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads
Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular Cell on p. 1232-1242.e4
Identification of regions in the Spt5 subunit of DRB sensitivity-inducing factor (DSIF) that are involved in promoter-proximal pausing
Yijun Qiu, David S. Gilmour, 2017, Journal of Biological Chemistry on p. 5555-5570
A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes
Douglas G. Baumann, David S. Gilmour, 2017, Nucleic Acids Research on p. 10481-10491
Mapping the Phosphorylation pattern of Drosophila melanogaster RNA polymerase II carboxyl-terminal domain using ultraviolet photodissociation mass spectrometry
Joshua E. Mayfield, Michelle R. Robinson, Victoria C. Cotham, Seema Irani, Wendy L. Matthews, Anjana Ram, David S. Gilmour, Joe R. Cannon, Yan Jessie Zhang, Jennifer S. Brodbelt, 2017, ACS Chemical Biology on p. 153-162