David Gilmour

Professor of Molecular and Cell Biology

David Gilmour

Research Summary

Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Huck Affiliations

Links

Publication Tags

Rna Polymerase Ii Phosphorylation Genes Drosophila Transcription Factors Gene Expression Transcription Rna Polymerase Iii Switches Mass Spectrometry Drosophila Melanogaster Chromatin Proteins Rna Proline Negative Elongation Factor Nucleic Acid Repetitive Sequences Dephosphorylation Tata Box Binding Protein Like Proteins Nexus Ribosomal Proteins Dichlororibofuranosylbenzimidazole Consensus Heterogeneity Elongation

Most Recent Publications

In silicons identification of Drosophila melanogaster genes encoding RNA polymerase subunits

Steven Marygold, Nazif Alic, David Gilmour, Savraj Grewal, microPublication Biology

Spt5-nucleic acid interactions are directly involved in promoter proximal pausing of RNA polymerase II

Roberta Dollinger, David S. Gilmour, 2022, FASEB Journal

Regulation of Promoter Proximal Pausing of RNA Polymerase II in Metazoans

Roberta Dollinger, David S. Gilmour, 2021, Journal of Molecular Biology

Genetic analysis of the RNA polymerase II CTD in Drosophila

Feiyue Lu, David S. Gilmour, 2019, ImmunoMethods on p. 129-137

The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads

Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular Cell on p. 1232-1242.e4

GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional coactivator

Douglas G. Baumann, Mu Shui Dai, Hua Lu, David S. Gilmour, 2018, Molecular and Cellular Biology

GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional co-activator.

D Baumann, M Dai, H Lu, David Gilmour, 2017, Molecular and cellular biology

A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes

Douglas G. Baumann, David S. Gilmour, 2017, Nucleic Acids Research on p. 10481-10491

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature Communications

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature Communications

Most-Cited Papers

XPaused Pol II coordinates tissue morphogenesis in the drosophila embryo

Mounia Lagha, Jacques P. Bothma, Emilia Esposito, Samuel Ng, Laura Stefanik, Chiahao Tsui, Jeffrey Johnston, Kai Chen, David S. Gilmour, Julia Zeitlinger, Michael S. Levine, 2013, Cell

Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor

Jian Li, David S. Gilmour, 2013, EMBO Journal on p. 1829-1841

Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing

Jian Li, Yingyun Liu, Ho Sung Rhee, Saikat Kumar B. Ghosh, Lu Bai, B. Franklin Pugh, David S. Gilmour, 2013, Molecular Cell on p. 711-722

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature Communications

Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription

Malini Natarajan, Gillian M. Schiralli Lester, Chanhyo Lee, Anamika Missra, Gregory A. Wasserman, Martin Steffen, David S. Gilmour, Andrew J. Henderson, 2013, Journal of Biological Chemistry on p. 25995-26003

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature Communications

The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads

Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular Cell on p. 1232-1242.e4

Identification of regions in the Spt5 subunit of DRB sensitivity-inducing factor (DSIF) that are involved in promoter-proximal pausing

Yijun Qiu, David S. Gilmour, 2017, Journal of Biological Chemistry on p. 5555-5570

A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes

Douglas G. Baumann, David S. Gilmour, 2017, Nucleic Acids Research on p. 10481-10491

Mapping the Phosphorylation pattern of Drosophila melanogaster RNA polymerase II carboxyl-terminal domain using ultraviolet photodissociation mass spectrometry

Joshua E. Mayfield, Michelle R. Robinson, Victoria C. Cotham, Seema Irani, Wendy L. Matthews, Anjana Ram, David S. Gilmour, Joe R. Cannon, Yan Jessie Zhang, Jennifer S. Brodbelt, 2017, ACS Chemical Biology on p. 153-162