David Gilmour

Professor of Molecular and Cell Biology

David Gilmour

Research Summary

Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Huck Affiliations

Links

Publication Tags

Rna Polymerase Ii Genes Phosphorylation Drosophila Gene Expression Transcription Factors Transcription Negative Elongation Factor Proteins Rna Chromatin Hot Temperature Dichlororibofuranosylbenzimidazole Rna Polymerase Iii Switches Histone Deacetylase 3 Elongation Chemical Activation Proline Drosophila Melanogaster Nucleic Acid Repetitive Sequences Dna Directed Rna Polymerases Shock Hiv Nexus

Most Recent Papers

Genetic analysis of the RNA polymerase II CTD in Drosophila

Feiyue Lu, David Scott Gilmour, 2019, Methods on p. 129-137

The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads

Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular cell on p. 1232-1242.e4

GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional coactivator

Douglas G. Baumann, Mu Shui Dai, Hua Lu, David S. Gilmour, 2018, Molecular and cellular biology

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature communications

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature communications

Identification of regions in the Spt5 subunit of DRB sensitivity-inducing factor (DSIF) that are involved in promoter-proximal pausing

Yijun Qiu, David S. Gilmour, 2017, Journal of Biological Chemistry on p. 5555-5570

Reconstitution of factor-dependent, promoter proximal pausing in Drosophila Nuclear Extracts

Jian Li, David Scott Gilmour, 2015, Methods in Molecular Biology on p. 133-152

RNAi screen in Drosophila larvae identifies histone deacetylase 3 as a positive regulator of the hsp70 heat shock gene expression during heat shock

Bhavana G. Achary, Katie M. Campbell, Ivy S. Co, David Scott Gilmour, 2014, Biochimica et Biophysica Acta - Gene Regulatory Mechanisms on p. 355-363

Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription

Malini Natarajan, Gillian M. Schiralli Lester, Chanhyo Lee, Anamika Missra, Gregory A. Wasserman, Martin Steffen, David S. Gilmour, Andrew J. Henderson, 2013, Journal of Biological Chemistry on p. 25995-26003

Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor

Jian Li, David S. Gilmour, 2013, EMBO Journal on p. 1829-1841

Most-Cited Papers

The multifunctional Ccr4-Not complex directly promotes transcription elongation

Jennifer A. Kruk, Arnob Dutta, Jianhua Fu, David S. Gilmour, Joseph C. Reese, 2011, Genes and Development on p. 581-593

XPaused Pol II coordinates tissue morphogenesis in the drosophila embryo

Mounia Lagha, Jacques P. Bothma, Emilia Esposito, Samuel Ng, Laura Stefanik, Chiahao Tsui, Jeffrey Johnston, Kai Chen, David S. Gilmour, Julia Zeitlinger, Michael S. Levine, 2013, Cell

Cohesin selectively binds and regulates genes with paused RNA polymerase

Avery Fay, Ziva Misulovin, Jian Li, Cheri A. Schaaf, Maria Gause, David S. Gilmour, Dale Dorsett, 2011, Current Biology on p. 1624-1634

Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor

Jian Li, David S. Gilmour, 2013, EMBO Journal on p. 1829-1841

Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription

Malini Natarajan, Gillian M. Schiralli Lester, Chanhyo Lee, Anamika Missra, Gregory A. Wasserman, Martin Steffen, David S. Gilmour, Andrew J. Henderson, 2013, Journal of Biological Chemistry on p. 25995-26003

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature communications

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature communications

Identification of regions in the Spt5 subunit of DRB sensitivity-inducing factor (DSIF) that are involved in promoter-proximal pausing

Yijun Qiu, David S. Gilmour, 2017, Journal of Biological Chemistry on p. 5555-5570

The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads

Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular cell on p. 1232-1242.e4

RNAi screen in Drosophila larvae identifies histone deacetylase 3 as a positive regulator of the hsp70 heat shock gene expression during heat shock

Bhavana G. Achary, Katie M. Campbell, Ivy S. Co, David Scott Gilmour, 2014, Biochimica et Biophysica Acta - Gene Regulatory Mechanisms on p. 355-363