David Gilmour

Professor of Molecular and Cell Biology

David Gilmour

Research Summary

Transcriptional regulation of the hsp70 heat shock gene in Drosophila.

Huck Affiliations

Links

Publication Tags

Rna Polymerase Ii Genes Phosphorylation Drosophila Negative Elongation Factor Transcription Factors Gene Expression Switches Mass Spectrometry Rna Transcription Rna Polymerase Iii Dichlororibofuranosylbenzimidazole Proline Drosophila Melanogaster Proteins Chromatin Dna Directed Rna Polymerases Hot Temperature Shock Messenger Rna Cohesins Nucleic Acid Repetitive Sequences Elongation Phosphoric Monoester Hydrolases

Most Recent Papers

Genetic analysis of the RNA polymerase II CTD in Drosophila

Feiyue Lu, David Scott Gilmour, 2019, Methods on p. 129-137

The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads

Feiyue Lu, Bede Portz, David S. Gilmour, 2019, Molecular cell on p. 1232-1242.e4

GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional coactivator

Douglas G. Baumann, Mu Shui Dai, Hua Lu, David S. Gilmour, 2018, Molecular and cellular biology

GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional co-activator.

D Baumann, M Dai, H Lu, David Gilmour, 2017, Molecular and cellular biology

A sequence-specific core promoter-binding transcription factor recruits TRF2 to coordinately transcribe ribosomal protein genes

Douglas G. Baumann, David Scott Gilmour, 2017, Nucleic acids research on p. 10481-10491

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature communications

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain

Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour, 2017, Nature communications

Identification of regions in the Spt5 subunit of DRB sensitivity-inducing factor (DSIF) that are involved in promoter-proximal pausing

Yijun Qiu, David S. Gilmour, 2017, Journal of Biological Chemistry on p. 5555-5570

Mapping the Phosphorylation pattern of Drosophila melanogaster RNA polymerase II carboxyl-terminal domain using ultraviolet photodissociation mass spectrometry

Joshua E. Mayfield, Michelle R. Robinson, Victoria C. Cotham, Seema Irani, Wendy L. Matthews, Anjana Ram, David Scott Gilmour, Joe R. Cannon, Yan Jessie Zhang, Jennifer S. Brodbelt, 2017, ACS chemical biology on p. 153-162

Reconstitution of factor-dependent, promoter proximal pausing in Drosophila Nuclear Extracts

Jian Li, David Scott Gilmour, 2015, Methods in Molecular Biology on p. 133-152

Most-Cited Papers

Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila

Filippo M. Cernilogar, Maria Cristina Onorati, Greg O. Kothe, A. Maxwell Burroughs, Krishna Mohan Parsi, Achim Breiling, Federica Lo Sardo, Alka Saxena, Keita Miyoshi, Haruhiko Siomi, Mikiko C. Siomi, Piero Carninci, David Scott Gilmour, Davide F.V. Corona, Valerio Orlando, 2011, Nature on p. 391-395

The multifunctional Ccr4-Not complex directly promotes transcription elongation

Jennifer A. Kruk, Arnob Dutta, Jianhua Fu, David S. Gilmour, Joseph C. Reese, 2011, Genes and Development on p. 581-593

XPaused Pol II coordinates tissue morphogenesis in the drosophila embryo

Mounia Lagha, Jacques P. Bothma, Emilia Esposito, Samuel Ng, Laura Stefanik, Chiahao Tsui, Jeffrey Johnston, Kai Chen, David S. Gilmour, Julia Zeitlinger, Michael S. Levine, 2013, Cell

Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex

Anamika Missra, David Scott Gilmour, 2010, Proceedings of the National Academy of Sciences of the United States of America on p. 11301-11306

Kinetic competition between elongation rate and binding of NELF controls promoter-proximal pausing

Jian Li, Yingyun Liu, Ho Sung Rhee, Saikat Kumar B. Ghosh, Lu Bai, B. Franklin Pugh, David S. Gilmour, 2013, Molecular Cell on p. 711-722

Cohesin selectively binds and regulates genes with paused RNA polymerase

Avery Fay, Ziva Misulovin, Jian Li, Cheri A. Schaaf, Maria Gause, David S. Gilmour, Dale Dorsett, 2011, Current Biology on p. 1624-1634

Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor

Jian Li, David S. Gilmour, 2013, EMBO Journal on p. 1829-1841

Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription

Malini Natarajan, Gillian M. Schiralli Lester, Chanhyo Lee, Anamika Missra, Gregory A. Wasserman, Martin Steffen, David S. Gilmour, Andrew J. Henderson, 2013, Journal of Biological Chemistry on p. 25995-26003

Negative elongation factor accelerates the rate at which heat shock genes are shut off by facilitating dissociation of heat shock factor

Saikat Kumar B. Ghosh, Anamika Missra, David Scott Gilmour, 2011, Molecular and cellular biology on p. 4232-4243

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain

Eric B. Gibbs, Feiyue Lu, Bede Portz, Michael J. Fisher, Brenda P. Medellin, Tatiana N. Laremore, Yan Jessie Zhang, David S. Gilmour, Scott A. Showalter, 2017, Nature communications