Darrell Cockburn
Assistant Professor of Food Science
-
428 Rodney A. Erickson Food Science
University Park, PA - dwc30@psu.edu
- 814-863-2950
Huck Affiliations
Publication Tags
Enzymes Starch Cellulose Glycoside Hydrolases Carbohydrates Binding Sites Polysaccharides Mutation Oligosaccharides Surface Plasmon Resonance Glucans Milk Proteins Catalysis Proteins Phylogeny Polymerization Molecular Weight Maltose Degradation Gene Expression Biochemistry Cracks Catalysts Electrophoresis BacteriaMost Recent Papers
Structural basis for the flexible recognition of α-glucan substrates by Bacteroides thetaiotaomicron SusG
Gregory Arnal, Darrell W. Cockburn, Harry Brumer, Nicole M. Koropatkin, 2018, Protein Science on p. 1093-1101
Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii
Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental microbiology on p. 324-336
Lysozyme activity of the Ruminococcus champanellensis cellulosome
Sarah Moraïs, Darrell W. Cockburn, Yonit Ben-David, Nicole M. Koropatkin, Eric C. Martens, Sylvia H. Duncan, Harry J. Flint, Itzhak Mizrahi, Edward A. Bayer, 2016, Environmental microbiology on p. 5112-5122
Using carbohydrate interaction assays to reveal novel binding sites in carbohydrate active enzymes
Darrell Cockburn, Casper Wilkens, Adiphol Dilokpimol, Hiroyuki Nakai, Anna Lewińska, Maher Abou Hachem, Birte Svensson, 2016, PloS one on p. e0160112
An efficient arabinoxylan-debranching α-l-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site
Casper Wilkens, Susan Andersen, Bent O. Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans E.M. Christensen, Birthe B. Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem, Birte Svensson, 2016, Applied Microbiology and Biotechnology on p. 6265-6277
Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation
Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345
Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230
A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night
Christian Ruzanski, Julia Smirnova, Martin Rejzek, Darrell Cockburn, Henriette L. Pedersen, Marilyn Pike, William G.T. Willats, Birte Svensson, Martin Steup, Oliver Ebenhöh, Alison M. Smith, Robert A. Field, 2013, Journal of Biological Chemistry on p. 28581-28598
Binding Interactions Between α-glucans from Lactobacillus reuteri and Milk Proteins Characterised by Surface Plasmon Resonance
Silja K. Diemer, Birte Svensson, Linnéa N. Babol, Darrell Cockburn, Pieter Grijpstra, Lubbert Dijkhuizen, Ditte M. Folkenberg, Christel Garrigues, Richard H. Ipsen, 2012, Food Biophysics on p. 220-226
Modulating the pH-activity profile of cellulase A from Cellulomonas fimi by replacement of surface residues
Darrell W. Cockburn, Anthony J. Clarke, 2011, Protein Engineering, Design and Selection on p. 429-437
Most-Cited Papers
Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230
Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation
Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345
Direct visualization of the enzymatic digestion of a single fiber of native cellulose in an aqueous environment by atomic force microscopy
Amanda Quirk, Jacek Lipkowski, Chris Vandenende, Darrell Cockburn, Anthony J. Clarke, John R. Dutcher, Sharon G. Roscoe, 2010, Langmuir on p. 5007-5013
A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night
Christian Ruzanski, Julia Smirnova, Martin Rejzek, Darrell Cockburn, Henriette L. Pedersen, Marilyn Pike, William G.T. Willats, Birte Svensson, Martin Steup, Oliver Ebenhöh, Alison M. Smith, Robert A. Field, 2013, Journal of Biological Chemistry on p. 28581-28598
Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii
Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental microbiology on p. 324-336
An efficient arabinoxylan-debranching α-l-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site
Casper Wilkens, Susan Andersen, Bent O. Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans E.M. Christensen, Birthe B. Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem, Birte Svensson, 2016, Applied Microbiology and Biotechnology on p. 6265-6277
Modulating the pH-activity profile of cellulase by substitution
Darrell Cockburn, Chris Vandenende, Anthony J. Clarke, 2010, Biochemistry on p. 2042-2050
Modulating the pH-activity profile of cellulase A from Cellulomonas fimi by replacement of surface residues
Darrell W. Cockburn, Anthony J. Clarke, 2011, Protein Engineering, Design and Selection on p. 429-437
Using carbohydrate interaction assays to reveal novel binding sites in carbohydrate active enzymes
Darrell Cockburn, Casper Wilkens, Adiphol Dilokpimol, Hiroyuki Nakai, Anna Lewińska, Maher Abou Hachem, Birte Svensson, 2016, PloS one on p. e0160112
Binding Interactions Between α-glucans from Lactobacillus reuteri and Milk Proteins Characterised by Surface Plasmon Resonance
Silja K. Diemer, Birte Svensson, Linnéa N. Babol, Darrell Cockburn, Pieter Grijpstra, Lubbert Dijkhuizen, Ditte M. Folkenberg, Christel Garrigues, Richard H. Ipsen, 2012, Food Biophysics on p. 220-226
News Articles Featuring Darrell Cockburn
Jan 05, 2020
5 Things You Can Do to Make Your Microbiome Healthier
Fresh fruits and vegetables are good for you and your gut microbes
Full Article
Jan 03, 2020
5 Things You Can Do To Make Your Microbiome Healthier
Fresh fruits and vegetables are good for you and your gut microbes.
Full Article
Jan 03, 2020
5 Things That Will Help Keep Your Microbiome Healthy
A healthy diet and lifestyle will help keep your gut microbes — and you — happy.
Full Article