Darrell Cockburn
Assistant Professor of Food Science
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428 Rodney A. Erickson Food Science
University Park, PA - dwc30@psu.edu
- 814-863-2950
Huck Affiliations
Publication Tags
Starch Enzymes Health Carbohydrates Binding Sites Oligosaccharides Polysaccharides Gastrointestinal Microbiome Amylases Microbiota Glycoside Hydrolases Surface Butyrates Fermentation Reconfigurable Hardware Maltose Binding Site Carbohydrate Glucans Escherichia Coli Degradation Ruminococcus Catalytic Domain Genetically Modified Plants MutationMost Recent Papers
Additional Resistant Starch from One Potato Side Dish per Day Alters the Gut Microbiota but Not Fecal Short-Chain Fatty Acid Concentrations
Peter Demartino, Emily A. Johnston, Kristina S. Petersen, Penny M. Kris-Etherton, Darrell W. Cockburn, 2022, Nutrients
Structure and substrate recognition by the Ruminococcus bromii amylosome pullulanases
Darrell W. Cockburn, Ryan Kibler, Haley A. Brown, Rebecca Duvall, Sarah Moraïs, Edward Bayer, Nicole M. Koropatkin, 2021, Journal of Structural Biology
In vitro Fermentation Reveals Changes in Butyrate Production Dependent on Resistant Starch Source and Microbiome Composition
June Teichmann, Darrell W. Cockburn, 2021, Frontiers in Microbiology
Characterization of Microbial Dynamics and Volatile Metabolome Changes During Fermentation of Chambourcin Hybrid Grapes From Two Pennsylvania Regions
Hung Li Wang, Helene Hopfer, Darrell W. Cockburn, Josephine Wee, 2021, Frontiers in Microbiology on p. 3454
A Modified Brewing Procedure Informed by the Enzymatic Profiles of Gluten-Free Malts Significantly Improves Fermentable Sugar Generation in Gluten-Free Brewing
Andrew Ledley, R Elias, H Hopfer, Darrell Cockburn, 2021, Beverages on p. 53
Resistant starch
Peter DeMartino, Darrell W. Cockburn, 2020, Current Opinion in Biotechnology on p. 66-71
EXPERTS WEIGH IN ON CURRENT JOB MARKET TRENDS
Darrell Cockburn, 2020, Zippia
The structures of the GH13_36 amylases from Eubacterium rectale and Ruminococcus bromii reveal subsite architectures that favor maltose production
Darrell Cockburn, Filipe Cerqueira, Constance Bahr, Nicole Koropatkin, 2020, Amylase on p. 24-44
5 things you can do to make your microbiome healthier
Darrell Cockburn, C Rogers, 2019, The Conversation
Structural basis for the flexible recognition of α-glucan substrates by Bacteroides thetaiotaomicron SusG
Gregory Arnal, Darrell W. Cockburn, Harry Brumer, Nicole M. Koropatkin, 2018, Protein Science on p. 1093-1101
Most-Cited Papers
Polysaccharide Degradation by the Intestinal Microbiota and Its Influence on Human Health and Disease
Darrell W. Cockburn, Nicole M. Koropatkin, 2016, Journal of Molecular Biology on p. 3230-3252
The Sus operon
Matthew H. Foley, Darrell W. Cockburn, Nicole M. Koropatkin, 2016, Cellular and Molecular Life Sciences on p. 2603-2617
Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230
Resistant starch
Peter DeMartino, Darrell W. Cockburn, 2020, Current Opinion in Biotechnology on p. 66-71
Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii
Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental Microbiology on p. 324-336
Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77 - a mini-review
Darrell Cockburn, Casper Wilkens, Christian Ruzanski, Susan Andersen, Jonas Willum Nielsen, Alison M. Smith, Robert A. Field, Martin Willemoës, Maher Abou Hachem, Birte Svensson, 2014, Biologia (Poland) on p. 705-712
Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation
Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345
Novel carbohydrate binding modules in the surface anchored α-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut
Darrell W. Cockburn, Carolyn Suh, Krizia Perez Medina, Rebecca M. Duvall, Zdzislaw Wawrzak, Bernard Henrissat, Nicole M. Koropatkin, 2018, Molecular Microbiology on p. 249-264
A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night
Christian Ruzanski, Julia Smirnova, Martin Rejzek, Darrell Cockburn, Henriette L. Pedersen, Marilyn Pike, William G.T. Willats, Birte Svensson, Martin Steup, Oliver Ebenhöh, Alison M. Smith, Robert A. Field, 2013, Journal of Biological Chemistry on p. 28581-28598
Surface binding sites in carbohydrate active enzymes
Darrell Cockburn, Birte Svensson, 2013, on p. 204-221
News Articles Featuring Darrell Cockburn
Sep 24, 2020
Penn State Microbiome Center elects new executive committee
The Penn State Microbiome Center in the Huck Institutes of the Life Sciences recently elected six new members to join its executive committee. The new members, along with 11 others who remained on the committee, started their two-year term in July.
Full Article
Jan 05, 2020
5 Things You Can Do to Make Your Microbiome Healthier
Fresh fruits and vegetables are good for you and your gut microbes
Full Article
Jan 03, 2020
5 Things You Can Do To Make Your Microbiome Healthier
Fresh fruits and vegetables are good for you and your gut microbes.
Full Article
Jan 03, 2020
5 Things That Will Help Keep Your Microbiome Healthy
A healthy diet and lifestyle will help keep your gut microbes — and you — happy.
Full Article