Darrell Cockburn

Assistant Professor of Food Science

Darrell Cockburn

Huck Affiliations

Publication Tags

Enzymes Starch Cellulose Glycoside Hydrolases Carbohydrates Binding Sites Polysaccharides Mutation Oligosaccharides Surface Plasmon Resonance Glucans Milk Proteins Catalysis Proteins Phylogeny Polymerization Molecular Weight Maltose Degradation Gene Expression Biochemistry Cracks Catalysts Electrophoresis Bacteria

Most Recent Papers

Structural basis for the flexible recognition of α-glucan substrates by Bacteroides thetaiotaomicron SusG

Gregory Arnal, Darrell W. Cockburn, Harry Brumer, Nicole M. Koropatkin, 2018, Protein Science on p. 1093-1101

Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental microbiology on p. 324-336

Lysozyme activity of the Ruminococcus champanellensis cellulosome

Sarah Moraïs, Darrell W. Cockburn, Yonit Ben-David, Nicole M. Koropatkin, Eric C. Martens, Sylvia H. Duncan, Harry J. Flint, Itzhak Mizrahi, Edward A. Bayer, 2016, Environmental microbiology on p. 5112-5122

Using carbohydrate interaction assays to reveal novel binding sites in carbohydrate active enzymes

Darrell Cockburn, Casper Wilkens, Adiphol Dilokpimol, Hiroyuki Nakai, Anna Lewińska, Maher Abou Hachem, Birte Svensson, 2016, PloS one on p. e0160112

An efficient arabinoxylan-debranching α-l-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site

Casper Wilkens, Susan Andersen, Bent O. Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans E.M. Christensen, Birthe B. Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem, Birte Svensson, 2016, Applied Microbiology and Biotechnology on p. 6265-6277

Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation

Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345

Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale

Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230

A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night

Christian Ruzanski, Julia Smirnova, Martin Rejzek, Darrell Cockburn, Henriette L. Pedersen, Marilyn Pike, William G.T. Willats, Birte Svensson, Martin Steup, Oliver Ebenhöh, Alison M. Smith, Robert A. Field, 2013, Journal of Biological Chemistry on p. 28581-28598

Binding Interactions Between α-glucans from Lactobacillus reuteri and Milk Proteins Characterised by Surface Plasmon Resonance

Silja K. Diemer, Birte Svensson, Linnéa N. Babol, Darrell Cockburn, Pieter Grijpstra, Lubbert Dijkhuizen, Ditte M. Folkenberg, Christel Garrigues, Richard H. Ipsen, 2012, Food Biophysics on p. 220-226

Modulating the pH-activity profile of cellulase A from Cellulomonas fimi by replacement of surface residues

Darrell W. Cockburn, Anthony J. Clarke, 2011, Protein Engineering, Design and Selection on p. 429-437

Most-Cited Papers

Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale

Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230

Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation

Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345

Direct visualization of the enzymatic digestion of a single fiber of native cellulose in an aqueous environment by atomic force microscopy

Amanda Quirk, Jacek Lipkowski, Chris Vandenende, Darrell Cockburn, Anthony J. Clarke, John R. Dutcher, Sharon G. Roscoe, 2010, Langmuir on p. 5007-5013

A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night

Christian Ruzanski, Julia Smirnova, Martin Rejzek, Darrell Cockburn, Henriette L. Pedersen, Marilyn Pike, William G.T. Willats, Birte Svensson, Martin Steup, Oliver Ebenhöh, Alison M. Smith, Robert A. Field, 2013, Journal of Biological Chemistry on p. 28581-28598

Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental microbiology on p. 324-336

An efficient arabinoxylan-debranching α-l-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site

Casper Wilkens, Susan Andersen, Bent O. Petersen, An Li, Marta Busse-Wicher, Johnny Birch, Darrell Cockburn, Hiroyuki Nakai, Hans E.M. Christensen, Birthe B. Kragelund, Paul Dupree, Barry McCleary, Ole Hindsgaul, Maher Abou Hachem, Birte Svensson, 2016, Applied Microbiology and Biotechnology on p. 6265-6277

Modulating the pH-activity profile of cellulase by substitution

Darrell Cockburn, Chris Vandenende, Anthony J. Clarke, 2010, Biochemistry on p. 2042-2050

Modulating the pH-activity profile of cellulase A from Cellulomonas fimi by replacement of surface residues

Darrell W. Cockburn, Anthony J. Clarke, 2011, Protein Engineering, Design and Selection on p. 429-437

Using carbohydrate interaction assays to reveal novel binding sites in carbohydrate active enzymes

Darrell Cockburn, Casper Wilkens, Adiphol Dilokpimol, Hiroyuki Nakai, Anna Lewińska, Maher Abou Hachem, Birte Svensson, 2016, PloS one on p. e0160112

Binding Interactions Between α-glucans from Lactobacillus reuteri and Milk Proteins Characterised by Surface Plasmon Resonance

Silja K. Diemer, Birte Svensson, Linnéa N. Babol, Darrell Cockburn, Pieter Grijpstra, Lubbert Dijkhuizen, Ditte M. Folkenberg, Christel Garrigues, Richard H. Ipsen, 2012, Food Biophysics on p. 220-226