Darrell Cockburn
Assistant Professor of Food Science

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428 Rodney A. Erickson Food Science
University Park, PA - dwc30@psu.edu
- 814-863-2950
Huck Affiliations
Publication Tags
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Starch Enzymes Carbohydrates Binding Sites Polysaccharides Oligosaccharides Health Amylases Degradation Gastrointestinal Microbiome Glycoside Hydrolases Surface Maltose Binding Site Mashing Fermentation Carbohydrate Sugars Surface Plasmon Resonance Escherichia Coli Eubacterium Genetically Modified Plants Sporulation Reconfigurable Hardware Structure Activity RelationshipMost Recent Publications
Microscopic assessment of the degradation of millet starch granules by endogenous and exogenous enzymes during mashing
Andrew J. Ledley, Gregory R. Ziegler, Ryan Elias, Darrell W. Cockburn, 2023, Carbohydrate Polymers
Evaluating the Role of Mashing in the Amino Acid Profiles of Worts Produced from Gluten-Free Malts
Andrew J. Ledley, Ryan J. Elias, Darrell W. Cockburn, 2023, Beverages
Evaluating the efficacy of non-thermal microbial load reduction treatments of heat labile food components for in vitro fermentation experiments
Andrew Paff, Darrell W. Cockburn, 2023, PLoS One
Affinity Electrophoresis for Analysis of Catalytic Module-Carbohydrate Interactions
Darrell W. Cockburn, Casper Wilkens, Birte Svensson, 2023, Methods in Molecular Biology on p. 91-101
Impact of mashing protocol on the formation of fermentable sugars from millet in gluten-free brewing
Andrew Ledley, R Elias, Darrell Cockburn, 2023, Food Chemistry on p. 134758
Surface Plasmon Resonance Analysis for Quantifying Protein-Carbohydrate Interactions
Marie Sofie Møller, Darrell W. Cockburn, Casper Wilkens, 2023, Methods in Molecular Biology on p. 141-150
Evaluating the role of mashing in the amino acid profiles of worts produced from gluten-free malts
Andrew Ledley, R Elias, Darrell Cockburn, 2023, Beverages on p. 10
Additional Resistant Starch from One Potato Side Dish per Day Alters the Gut Microbiota but Not Fecal Short-Chain Fatty Acid Concentrations
P DeMartino, E Johnston, K Petersen, Penny Kris-Etherton, Darrell W. Cockburn, 2022, Nutrients
Resistant starch: the dietary fiber of the starch world
Darrell Cockburn, 2022, on p. 197-218
Effect of processing on the anti-inflammatory efficacy of cocoa in a high fat diet-induced mouse model of obesity
D. Weikart, V. Indukuri, K. Racine, K. Coleman, Jasna Kovac, Darrell Cockburn, Helene Hopfer, A. Neilson, Joshua D. Lambert, 2022, Nutrition Reports International
Most-Cited Papers
Polysaccharide Degradation by the Intestinal Microbiota and Its Influence on Human Health and Disease
Darrell W. Cockburn, Nicole M. Koropatkin, 2016, Journal of Molecular Biology on p. 3230-3252
Resistant starch: impact on the gut microbiome and health
Peter DeMartino, Darrell W. Cockburn, 2020, Current Opinion in Biotechnology on p. 66-71
The Sus operon: a model system for starch uptake by the human gut Bacteroidetes
Matthew H. Foley, Darrell W. Cockburn, Nicole M. Koropatkin, 2016, Cellular and Molecular Life Sciences on p. 2603-2617
Molecular details of a starch utilization pathway in the human gut symbiont Eubacterium rectale
Darrell W. Cockburn, Nicole I. Orlovsky, Matthew H. Foley, Kurt J. Kwiatkowski, Constance M. Bahr, Mallory Maynard, Borries Demeler, Nicole M. Koropatkin, 2015, Molecular Microbiology on p. 209-230
Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii
Indrani Mukhopadhya, Sarah Moraïs, Jenny Laverde-Gomez, Paul O. Sheridan, Alan W. Walker, William Kelly, Athol V. Klieve, Diane Ouwerkerk, Sylvia H. Duncan, Petra Louis, Nicole Koropatkin, Darrell Cockburn, Ryan Kibler, Philip J. Cooper, Carlos Sandoval, Emmanuelle Crost, Nathalie Juge, Edward A. Bayer, Harry J. Flint, 2018, Environmental Microbiology on p. 324-336
Analysis of surface binding sites (SBSs) in carbohydrate active enzymes with focus on glycoside hydrolase families 13 and 77 - a mini-review
Darrell Cockburn, Casper Wilkens, Christian Ruzanski, Susan Andersen, Jonas Willum Nielsen, Alison M. Smith, Robert A. Field, Martin Willemoës, Maher Abou Hachem, Birte Svensson, 2014, Biologia (Poland) on p. 705-712
Surface binding sites in amylase have distinct roles in recognition of starch structure motifs and degradation
Darrell Cockburn, Morten M. Nielsen, Camilla Christiansen, Joakim M. Andersen, Julie B. Rannes, Andreas Blennow, Birte Svensson, 2015, International Journal of Biological Macromolecules on p. 338-345
Novel carbohydrate binding modules in the surface anchored α-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut
Darrell W. Cockburn, Carolyn Suh, Krizia Perez Medina, Rebecca M. Duvall, Zdzislaw Wawrzak, Bernard Henrissat, Nicole M. Koropatkin, 2018, Molecular Microbiology on p. 249-264
A bacterial glucanotransferase can replace the complex maltose metabolism required for starch to sucrose conversion in leaves at night
Christian Ruzanski, Julia Smirnova, Martin Rejzek, Darrell Cockburn, Henriette L. Pedersen, Marilyn Pike, William G.T. Willats, Birte Svensson, Martin Steup, Oliver Ebenhöh, Alison M. Smith, Robert A. Field, 2013, Journal of Biological Chemistry on p. 28581-28598
Surface binding sites in carbohydrate active enzymes: An emerging picture of structural and functional diversity
Darrell Cockburn, Birte Svensson, 2013, on p. 204-221
News Articles Featuring Darrell Cockburn
Feb 24, 2023
Processing, like fermentation and roasting, doesn’t cut cocoa’s health benefits
It is widely believed that when foods undergo processing, their health benefits are reduced. But that is not true for cocoa, according to a Penn State-led team of researchers, who conducted a new study using a mouse model.
Full Article
Sep 24, 2020
Penn State Microbiome Center elects new executive committee
The Penn State Microbiome Center in the Huck Institutes of the Life Sciences recently elected six new members to join its executive committee. The new members, along with 11 others who remained on the committee, started their two-year term in July.
Full Article
Jan 05, 2020
5 Things You Can Do to Make Your Microbiome Healthier
Fresh fruits and vegetables are good for you and your gut microbes
Full Article
Jan 03, 2020
5 Things You Can Do To Make Your Microbiome Healthier
Fresh fruits and vegetables are good for you and your gut microbes.
Full Article
Jan 03, 2020
5 Things That Will Help Keep Your Microbiome Healthy
A healthy diet and lifestyle will help keep your gut microbes — and you — happy.
Full Article