Colin Barnstable

Professor and Chair of Neural Behavioral Sciences

H109 Neural & Behavioral Sciences
Hershey, PA
cjb30@psu.edu
717-531-3631

Bio & Links
Publications

Research Summary

How interacting networks of transcription factors and signal transduction molecules guide the development of precursor/stem cells into mature neurons. Role of these networks in neurodegenerative diseases. Factors that can act as neuroprotective agents.

Huck Affiliations

Bioinformatics and Genomics

Most Recent Publications

Extremely Low-Frequency and Low-Intensity Electromagnetic Field Technology (ELF-EMF) Sculpts Microtubules

Alexandra Lobyntseva, Maram Ganaiem, Yanina Ivashko-Pachima, Colin J Barnstable, Batsheva Weisinger, Ana Parabucki, Yaron Segal, Esther Shohami, Illana Gozes, 2025, European Journal of Neuroscience

A PEDF peptide mimetic effectively relieves dry eye in a diabetic murine model by restoring corneal nerve, barrier, and lacrimal gland function

Shuangping Chen, Colin James Barnstable, Xiaomin Zhang, Xiaorong Li, Shaozhen Zhao, Joyce Tombran-Tink, 2024, Ocular Surface on p. 1-12

Temporal changes in mouse hippocampus transcriptome after pilocarpine-induced seizures

Evgenya Y. Popova, Yuka Imamura Kawasawa, Ming Leung, Colin J. Barnstable, 2024, Frontiers in Neuroscience

Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells

Changjie Ren, Peiran Zhou, Mingliang Zhang, Zihao Yu, Xiaomin Zhang, Joyce Tombran-Tink, Colin J. Barnstable, Xiaorong Li, 2023, International Journal of Molecular Sciences

Deletion of the Pedf gene leads to inflammation, photoreceptor loss and vascular disturbances in the retina

Xin Chen, Manhong Xu, Xiaomin Zhang, Colin J. Barnstable, Xiaorong Li, Joyce Tombran-Tink, 2022, Experimental Eye Research

Regenerative Medicine, Advanced Stem Cell, and Gene Therapies for Eye Diseases

Colin J. Barnstable, Jost B. Jonas, Kang Zhang, 2022, Asia-Pacific Journal of Ophthalmology on p. 299-301

Epigenetics and Degenerative Retinal Diseases: Prospects for New Therapeutic Approaches

Colin J. Barnstable, 2022, Asia-Pacific Journal of Ophthalmology on p. 328-334

Uncoupling Proteins as Therapeutic Targets for Neurodegenerative Diseases

Colin J. Barnstable, Mingliang Zhang, Joyce Tombran-Tink, 2022, International Journal of Molecular Sciences

Novel Regulators of Retina Neovascularization: A Proteomics Approach

Manhong Xu, Yilin Jiang, Lin Su, Xin Chen, Xianfeng Shao, Vicki Ea, Zhenying Shang, Xiaomin Zhang, Colin J. Barnstable, Xiaorong Li, Joyce Tombran-Tink, 2022, Journal of Proteome Research on p. 101-117

Neuroprotection of retinal cells by Caffeic Acid Phenylethyl Ester（CAPE) is mediated by mitochondrial uncoupling protein UCP2

Mingliang Zhang, Liming Wang, Dejia Wen, Changjie Ren, Shuang Chen, Zhihui Zhang, Lanlan Hu, Zihao Yu, Joyce Tombran-Tink, Xiaomin Zhang, Xiaorong Li, Colin J. Barnstable, 2021, Neurochemistry International

Most-Cited Papers

Uncoupling proteins in the mitochondrial defense against oxidative stress

Daniel T. Hass, Colin J. Barnstable, 2021, Progress in Retinal Research

Mitochondrial uncoupling protein 2 knock-out promotes mitophagy to decrease retinal ganglion cell death in a mouse model of glaucoma

Daniel T. Hass, Colin J. Barnstable, 2019, Journal of Neuroscience on p. 3582-3596

LSD1-Mediated Demethylation of H3K4me2 Is Required for the Transition from Late Progenitor to Differentiated Mouse Rod Photoreceptor

Evgenya Y. Popova, Carolina Pinzon-Guzman, Anna C. Salzberg, Samuel Shao Min Zhang, Colin J. Barnstable, 2016, Molecular Neurobiology on p. 4563-4581

Histone deacetylase 1 is essential for rod photoreceptor differentiation by regulating acetylation at histone H3 lysine 9 and histone H4 lysine 12 in the mouse retina

Renata C. Ferreira, Evgenya Y. Popova, Jessica James, Marcelo R.S. Briones, Samuel S. Zhang, Colin J. Barnstable, 2017, Journal of Biological Chemistry on p. 2422-2440

Uncoupling protein 2 in the glial response to stress: Implications for neuroprotection

Daniel T. Hass, Colin J. Barnstable, 2016, Neural Regeneration Research on p. 1197-1200

Therapeutic Retrobulbar Inhibition of STAT3 Protects Ischemic Retina Ganglion Cells

Mansin Wong, Ying Li, Shang Li, Shaodan Zhang, Weiyi Li, Pei Zhang, Chaoran Chen, Colin J. Barnstable, Samuel S. Zhang, Chun Zhang, Ping Huang, 2015, Molecular Neurobiology on p. 1364-1377