Christopher Norbury

Professor of Microbiology

Christopher Norbury

Huck Affiliations

Publication Tags

Vaccinia Virus Infection Proteins T Lymphocytes Viruses Infections Virus Diseases Dendritic Cells Virion Glycoproteins T Cells Peptides Macrophages Parasites Cross Priming Cells Histocompatibility Antigens Class I Interferon Type I Malaria Protein Molecule Interleukin 4 Immunity Ectromelia Virus Antigens

Most Recent Publications

An increase in glycoprotein concentration on extracellular virions dramatically alters vaccinia virus infectivity and pathogenesis without impacting immunogenicity

Stephanie R. Monticelli, Peter Bryk, Matthew G. Brewer, Hector C. Aguilar, Christopher C. Norbury, Brian M. Ward, 2021, PLoS Pathogens

IL-4 treatment mitigates experimental cerebral malaria by reducing parasitemia, dampening inflammation, and lessening the cytotoxicity of T cells

Xianzhu Wu, Ramesh P. Thylur, Kiran K. Dayanand, Kishore Punnath, Christopher C. Norbury, D. Channe Gowda, 2021, Journal of Immunology on p. 118-131

IL-4Rα signaling by CD8α<sup>+</sup> dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8<sup>+</sup> T cell responses

Xianzhu Wu, Frank Brombacher, Zissis C. Chroneos, Christopher C. Norbury, D. Channe Gowda, 2021, Journal of Biological Chemistry

Vaccinia Virus Glycoproteins A33, A34, and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport

Stephanie R. Monticelli, Amalia K. Earley, Raychel Stone, Christopher C. Norbury, Brian M. Ward, 2020, Journal of Virology

Analysis of MHC Class I Processing Pathways That Generate a Response to Vaccinia Virus Late Proteins

Ting Kuang Niu, Michael F. Princiotta, Janet J. Sei, Christopher C. Norbury, 2019, ImmunoHorizons on p. 559-572

Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden

Nikhil J. Parekh, Tracy E. Krouse, Irene E. Reider, Ryan P. Hobbs, Brian M. Ward, Christopher C. Norbury, 2019, PLoS Pathogens

Small Molecule– based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes

Xianzhu Wu, Kiran K. Dayanand, Ramesh P. Thylur, Christopher C. Norbury, D. Channe Gowda, 2017, Journal of Biological Chemistry on p. 13615-13634

A systemic macrophage response is required to contain a peripheral poxvirus infection

Michael L. Davies, Nikhil J. Parekh, Lauren W. Kaminsky, Chetna Soni, Irene E. Reider, Tracy E. Krouse, Matthew A. Fischer, Nico van Rooijen, Ziaur S.M. Rahman, Christopher C. Norbury, 2017, PLoS Pathogens

Editorial overview: Antigen processing

Christopher C. Norbury, Laurence C. Eisenlohr, 2016, Current Opinion in Immunology on p. v-vi

Defining cross presentation for a wider audience

Christopher C. Norbury, 2016, Current Opinion in Immunology on p. 110-116

Most-Cited Papers

Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection

Daniel Rubio, Ren Huan Xu, Sanda Remakus, Tracy E. Krouse, Mary Ellen Truckenmiller, Roshan J. Thapa, Siddharth Balachandran, Antonio Alcamí, Christopher C. Norbury, Luis J. Sigal, 2013, Cell Host and Microbe on p. 701-710

Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation

Janet J. Sei, Scott Haskett, Lauren W. Kaminsky, Eugene Lin, Mary E. Truckenmiller, Clifford J. Bellone, R. Mark Buller, Christopher C. Norbury, 2015, PLoS Pathogens

C-Myc regulation by costimulatory signals modulates the generation of CD8<sup>+</sup> memory T cells during viral infection

Jianxun Song, Mohammad Haque, Jianyong Song, Kristin Fino, Youfei Wang, Praneet Sandhu, Xinmeng Song, Christopher Norbury, Bing Ni, Deyu Fang, Shahram Salek-Ardakani, 2016, Open Biology

Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation

Erica L. Heipertz, Michael L. Davies, Eugene Lin, Christopher C. Norbury, 2014, Journal of Immunology on p. 4169-4177

Defining cross presentation for a wider audience

Christopher C. Norbury, 2016, Current Opinion in Immunology on p. 110-116

MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve toll-like receptor 2

Michael L. Davies, Janet J. Sei, Nicholas A. Siciliano, Ren Huan Xu, Felicia Roscoe, Luis J. Sigal, Laurence C. Eisenlohr, Christopher C. Norbury, 2014, Journal of Virology on p. 3557-3567

Small Molecule– based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes

Xianzhu Wu, Kiran K. Dayanand, Ramesh P. Thylur, Christopher C. Norbury, D. Channe Gowda, 2017, Journal of Biological Chemistry on p. 13615-13634

Redundant function of plasmacytoid and conventional dendritic cells is required to survive a natural virus infection

Lauren W. Kaminsky, Janet J. Sei, Nikhil J. Parekh, Michael L. Davies, Irene E. Reider, Tracy E. Krouse, Christopher C. Norbury, 2015, Journal of Virology on p. 9974-9985

A systemic macrophage response is required to contain a peripheral poxvirus infection

Michael L. Davies, Nikhil J. Parekh, Lauren W. Kaminsky, Chetna Soni, Irene E. Reider, Tracy E. Krouse, Matthew A. Fischer, Nico van Rooijen, Ziaur S.M. Rahman, Christopher C. Norbury, 2017, PLoS Pathogens

Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden

Nikhil J. Parekh, Tracy E. Krouse, Irene E. Reider, Ryan P. Hobbs, Brian M. Ward, Christopher C. Norbury, 2019, PLoS Pathogens