Christopher Norbury

Professor of Microbiology

Christopher Norbury

Huck Affiliations

Publication Tags

Virus Diseases Infection T Lymphocytes Viruses Dendritic Cells Vaccinia Virus Immunity Interferon Type I Peptides Cross Priming Toll Like Receptor 2 Antiviral Agents T Cells Ectromelia Virus Antigen Presentation Macrophages Proteins Phenotype Antigens Retina Glucocorticoids Data Storage Equipment I Antigen Nf Kappa B Autoimmune Diseases

Most Recent Papers

Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden

Nikhil J. Parekh, Tracy E. Krouse, Irene E. Reider, Ryan P. Hobbs, Brian M. Ward, Christopher C. Norbury, 2019, PLoS pathogens

A systemic macrophage response is required to contain a peripheral poxvirus infection

Michael L. Davies, Nikhil J. Parekh, Lauren W. Kaminsky, Chetna Soni, Irene E. Reider, Tracy E. Krouse, Matthew A. Fischer, Nico van Rooijen, Ziaur S.M. Rahman, Christopher C. Norbury, 2017, PLoS pathogens

Small Molecule– based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes

Xianzhu Wu, Kiran K. Dayanand, Ramesh P. Thylur, Christopher C. Norbury, D. Channe Gowda, 2017, Journal of Biological Chemistry on p. 13615-13634

C-Myc regulation by costimulatory signals modulates the generation of CD8<sup>+</sup> memory T cells during viral infection

Jianxun Song, Mohammad Haque, Jianyong Song, Kristin Fino, Youfei Wang, Praneet Sandhu, Xinmeng Song, Christopher Norbury, Bing Ni, Deyu Fang, Shahram Salek-Ardakani, 2016, Open biology

Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation

Janet J. Sei, Scott Haskett, Lauren W. Kaminsky, Eugene Lin, Mary E. Truckenmiller, Clifford J. Bellone, R. Mark Buller, Christopher C. Norbury, 2015, PLoS pathogens

Redundant function of plasmacytoid and conventional dendritic cells is required to survive a natural virus infection

Lauren W. Kaminsky, Janet J. Sei, Nikhil J. Parekh, Michael L. Davies, Irene E. Reider, Tracy E. Krouse, Christopher C. Norbury, 2015, Journal of virology on p. 9974-9985

Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation

Erica L. Heipertz, Michael L. Davies, Eugene Lin, Christopher Norbury, 2014, Journal of Immunology on p. 4169-4177

MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve toll-like receptor 2

Michael L. Davies, Janet J. Sei, Nicholas A. Siciliano, Ren Huan Xu, Felicia Roscoe, Luis J. Sigal, Laurence C. Eisenlohr, Christopher C. Norbury, 2014, Journal of virology on p. 3557-3567

Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection

Daniel Rubio, Ren Huan Xu, Sanda Remakus, Tracy E. Krouse, Mary Ellen Truckenmiller, Roshan J. Thapa, Siddharth Balachandran, Antonio Alcamí, Christopher C. Norbury, Luis J. Sigal, 2013, Cell Host and Microbe on p. 701-710

Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina

Neal D. Heuss, Ute Lehmann, Christopher C. Norbury, Scott W. McPherson, Dale S. Gregerson, 2012, Journal of Immunology on p. 1191-1200

Most-Cited Papers

Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection

Daniel Rubio, Ren Huan Xu, Sanda Remakus, Tracy E. Krouse, Mary Ellen Truckenmiller, Roshan J. Thapa, Siddharth Balachandran, Antonio Alcamí, Christopher C. Norbury, Luis J. Sigal, 2013, Cell Host and Microbe on p. 701-710

Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function

Michael D. Elftman, John T. Hunzeker, Jennifer C. Mellinger, Robert H. Bonneau, Christopher C. Norbury, Mary E. Truckenmiller, 2010, Journal of Immunology on p. 1867-1875

CD11b<sup>+</sup>, Ly6G<sup>+</sup> cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection

Matthew A. Fischer, Michael L. Davies, Irene E. Reider, Erica L. Heipertz, Melanie R. Epler, Janet J. Sei, Molly A. Ingersoll, Nico van Rooijen, Gwendalyn J. Randolph, Christopher C. Norbury, 2011, PLoS pathogens

Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina

Neal D. Heuss, Ute Lehmann, Christopher C. Norbury, Scott W. McPherson, Dale S. Gregerson, 2012, Journal of Immunology on p. 1191-1200

A marked reduction in priming of cytotoxic CD8<sup>+</sup> T cells mediated by stress-induced glucocorticoids involves multiple deficiencies in cross-presentation by dendritic cells

John T. Hunzeker, Michael D. Elftman, Jennifer C. Mellinger, Michael F. Princiotta, Robert H. Bonneau, Mary E. Truckenmiller, Christopher C. Norbury, 2011, Journal of Immunology on p. 183-194

Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver

Ren Huan Xu, Daniel Rubio, Felicia Roscoe, Tracy E. Krouse, Mary Ellen Truckenmiller, Christopher C. Norbury, Paul N. Hudson, Inger K. Damon, Antonio Alcamí, Luis J. Sigal, 2012, PLoS pathogens

Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation

Janet J. Sei, Scott Haskett, Lauren W. Kaminsky, Eugene Lin, Mary E. Truckenmiller, Clifford J. Bellone, R. Mark Buller, Christopher C. Norbury, 2015, PLoS pathogens

Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation

Erica L. Heipertz, Michael L. Davies, Eugene Lin, Christopher Norbury, 2014, Journal of Immunology on p. 4169-4177

C-Myc regulation by costimulatory signals modulates the generation of CD8<sup>+</sup> memory T cells during viral infection

Jianxun Song, Mohammad Haque, Jianyong Song, Kristin Fino, Youfei Wang, Praneet Sandhu, Xinmeng Song, Christopher Norbury, Bing Ni, Deyu Fang, Shahram Salek-Ardakani, 2016, Open biology

MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve toll-like receptor 2

Michael L. Davies, Janet J. Sei, Nicholas A. Siciliano, Ren Huan Xu, Felicia Roscoe, Luis J. Sigal, Laurence C. Eisenlohr, Christopher C. Norbury, 2014, Journal of virology on p. 3557-3567