Christopher Norbury

Professor of Microbiology

Christopher Norbury

Huck Affiliations

Publication Tags

T Lymphocytes Virus Diseases Infection Vaccinia Virus Dendritic Cells Peptides Cross Priming Viruses Histocompatibility Antigens Class I Interferon Type I T Cells Proteins Antigens Interleukin 4 Immunity Cerebral Malaria Phenotype Malaria Parasites I Antigen Endoplasmic Reticulum Antigen Presenting Cells Data Storage Equipment Glycoproteins Virion

Most Recent Papers

IL-4 treatment mitigates experimental cerebral malaria by reducing parasitemia, dampening inflammation, and lessening the cytotoxicity of T cells

Xianzhu Wu, Ramesh P. Thylur, Kiran K. Dayanand, Kishore Punnath, Christopher C. Norbury, D. Channe Gowda, 2021, Journal of Immunology on p. 118-131

IL-4Rα signaling by CD8α<sup>+</sup> dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8<sup>+</sup> T cell responses

Xianzhu Wu, Frank Brombacher, Zissis C. Chroneos, Christopher C. Norbury, D. Channe Gowda, 2021, Journal of Biological Chemistry

Vaccinia Virus Glycoproteins A33, A34, and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport

Stephanie R. Monticelli, Amalia K. Earley, Raychel Stone, Christopher C. Norbury, Brian M. Ward, 2020, Journal of Virology

Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden

Nikhil J. Parekh, Tracy E. Krouse, Irene E. Reider, Ryan P. Hobbs, Brian M. Ward, Christopher C. Norbury, 2019, PLoS Pathogens

Small Molecule– based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes

Xianzhu Wu, Kiran K. Dayanand, Ramesh P. Thylur, Christopher C. Norbury, D. Channe Gowda, 2017, Journal of Biological Chemistry on p. 13615-13634

A systemic macrophage response is required to contain a peripheral poxvirus infection

Michael L. Davies, Nikhil J. Parekh, Lauren W. Kaminsky, Chetna Soni, Irene E. Reider, Tracy E. Krouse, Matthew A. Fischer, Nico van Rooijen, Ziaur S.M. Rahman, Christopher C. Norbury, 2017, PLoS Pathogens

Defining cross presentation for a wider audience

Christopher C. Norbury, 2016, Current Opinion in Immunology on p. 110-116

Editorial overview

Christopher C. Norbury, Laurence C. Eisenlohr, 2016, Current Opinion in Immunology on p. v-vi

C-Myc regulation by costimulatory signals modulates the generation of CD8<sup>+</sup> memory T cells during viral infection

Jianxun Song, Mohammad Haque, Jianyong Song, Kristin Fino, Youfei Wang, Praneet Sandhu, Xinmeng Song, Christopher Norbury, Bing Ni, Deyu Fang, Shahram Salek-Ardakani, 2016, Open Biology

Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation

Janet J. Sei, Scott Haskett, Lauren W. Kaminsky, Eugene Lin, Mary E. Truckenmiller, Clifford J. Bellone, R. Mark Buller, Christopher C. Norbury, 2015, PLoS Pathogens

Most-Cited Papers

Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection

Daniel Rubio, Ren Huan Xu, Sanda Remakus, Tracy E. Krouse, Mary Ellen Truckenmiller, Roshan J. Thapa, Siddharth Balachandran, Antonio Alcamí, Christopher C. Norbury, Luis J. Sigal, 2013, Cell Host and Microbe on p. 701-710

CD11b<sup>+</sup>, Ly6G<sup>+</sup> cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection

Matthew A. Fischer, Michael L. Davies, Irene E. Reider, Erica L. Heipertz, Melanie R. Epler, Janet J. Sei, Molly A. Ingersoll, Nico van Rooijen, Gwendalyn J. Randolph, Christopher C. Norbury, 2011, PLoS Pathogens

Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina

Neal D. Heuss, Ute Lehmann, Christopher C. Norbury, Scott W. McPherson, Dale S. Gregerson, 2012, Journal of Immunology on p. 1191-1200

A marked reduction in priming of cytotoxic CD8<sup>+</sup> T cells mediated by stress-induced glucocorticoids involves multiple deficiencies in cross-presentation by dendritic cells

John T. Hunzeker, Michael D. Elftman, Jennifer C. Mellinger, Michael F. Princiotta, Robert H. Bonneau, Mary E. Truckenmiller, Christopher C. Norbury, 2011, Journal of Immunology on p. 183-194

Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver

Ren Huan Xu, Daniel Rubio, Felicia Roscoe, Tracy E. Krouse, Mary Ellen Truckenmiller, Christopher C. Norbury, Paul N. Hudson, Inger K. Damon, Antonio Alcamí, Luis J. Sigal, 2012, PLoS Pathogens

Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation

Janet J. Sei, Scott Haskett, Lauren W. Kaminsky, Eugene Lin, Mary E. Truckenmiller, Clifford J. Bellone, R. Mark Buller, Christopher C. Norbury, 2015, PLoS Pathogens

C-Myc regulation by costimulatory signals modulates the generation of CD8<sup>+</sup> memory T cells during viral infection

Jianxun Song, Mohammad Haque, Jianyong Song, Kristin Fino, Youfei Wang, Praneet Sandhu, Xinmeng Song, Christopher Norbury, Bing Ni, Deyu Fang, Shahram Salek-Ardakani, 2016, Open Biology

Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation

Erica L. Heipertz, Michael L. Davies, Eugene Lin, Christopher C. Norbury, 2014, Journal of Immunology on p. 4169-4177

MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve toll-like receptor 2

Michael L. Davies, Janet J. Sei, Nicholas A. Siciliano, Ren Huan Xu, Felicia Roscoe, Luis J. Sigal, Laurence C. Eisenlohr, Christopher C. Norbury, 2014, Journal of Virology on p. 3557-3567

Defining cross presentation for a wider audience

Christopher C. Norbury, 2016, Current Opinion in Immunology on p. 110-116