Bruce Gluckman

Director of the Center for Neural Engineering; Professor of Engineering Science and Mechanics, of Neurosurgery, and of Biomedical Engineering

Bruce Gluckman

Research Summary

The dynamics of neural systems, how group dynamics form or emerge from the coupled dynamics of individual units, and how to measure and interact with these systems.

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Glucose Brain Sleep Diabetes Epilepsy Data Assimilation Forecasting Forecast Type 2 Diabetes Mellitus Glass Seizures Transducers Neuroimaging Geometry Medical Problems Mice Thermistors Sudden Death Optical Imaging Education Sudden Unexpected Death In Epilepsy Noninsulin Dependent Diabetes Mellitus Temperature Distribution Animals Kalman Filters

Most Recent Publications

Control of Spreading Depression with Electrical Fields

Andrew Whalen, Ying Xiao, Herve Kadji, Markus Dahlem, Bruce Gluckman, S Schiff,

Inferring Insulin Secretion Rate from Sparse Patient Glucose and Insulin Measures

Rammah M. Abohtyra, Christine L. Chan, David J. Albers, Bruce J. Gluckman, 2022, Frontiers in Physiology

Optimization of an unscented Kalman filter for an embedded platform

Philip Graybill, Bruce Gluckman, Mehdi Kiani, 2022, Computers in Biology and Medicine on p. 105557

Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window

Shubham Mirg, Haoyang Chen, Kevin Turner, Kyle Gheres, Jinyun Liu, Bruce J. Gluckman, Patrick Drew, Sri Rajasekhar Kothapalli, 2022, Optics Letters on p. 1121-1124

An optimized geometry for simultaneous functional ultrasound and photoacoustic imaging

Jinyun Liu, Haoyang Chen, Sumit Agrawal, Nanyin Zhang, Bruce Gluckman, Sri Rajasekhar Kothapalli, 2022,

Development of Mechanistic Neural Mass (mNM) Models that Link Physiology to Mean-Field Dynamics

Richa Tripathi, Bruce J. Gluckman, 2022, Frontiers in Network Physiology

Erratum: Personalized glucose forecasting for type 2 diabetes using data assimilation (PLoS Comput Biol 13: 4 (E1005232) DOI: 10.1371/journal.pcbi.1005232)

David J. Albers, Matthew Levine, Bruce Gluckman, Henry Ginsberg, George Hripcsak, Lena Mamykina, 2021, PLoS Computational Biology

Proceedings of the Sleep and Epilepsy Workshop: Section 3 Mortality: Sleep, Night, and SUDEP

Gordon F. Buchanan, Bruce J. Gluckman, Franck K. Kalume, Samden Lhatoo, Rama K. Maganti, Jeffrey L. Noebels, Kristina A. Simeone, Mark S. Quigg, Milena K. Pavlova, 2021, Epilepsy Currents on p. 215-219

Proceedings of the Sleep and Epilepsy Workshop: Section 1 Decreasing Seizures: Improving Sleep and Seizures, Themes for Future Research

Mark Quigg, Carl W. Bazil, Melanie Boly, Erik St Louis, Judy Liu, Louis Ptacek, Rama Maganti, Frank Kalume, Bruce J. Gluckman, Jay Pathmanathan, Milena K. Pavlova, Gordon F. Buchanan, 2021, Epilepsy Currents on p. 204-209

Model-based analysis and forecast of sleep-wake regulatory dynamics: Tools and applications to data

F. Bahari, J. Kimbugwe, K. D. Alloway, B. J. Gluckman, 2021, Chaos

Most-Cited Papers

Personalized glucose forecasting for type 2 diabetes using data assimilation

David J. Albers, Matthew Levine, Bruce Gluckman, Henry Ginsberg, George Hripcsak, Lena Mamykina, 2017, PLoS Computational Biology

Rapid eye movement sleep and hippocampal theta oscillations precede seizure onset in the tetanus toxin model of temporal lobe epilepsy

Madineh Sedigh-Sarvestani, Godfrey I. Thuku, Sridhar Sunderam, Anjum Parkar, Steven L. Weinstein, Steven J. Schiff, Bruce J. Gluckman, 2014, Journal of Neuroscience on p. 1105-1114

Functional hyperemia drives fluid exchange in the paravascular space

Ravi Kedarasetti, Kevin Turner, Christina Echagarruga, Bruce J. Gluckman, Patrick J. Drew, Francesco Costanzo, 2020, Fluids and Barriers of the CNS on p. 52-1–52-25

Mechanistic machine learning: How data assimilation leverages physiologic knowledge using Bayesian inference to forecast the future, infer the present, and phenotype

David J. Albers, Matthew E. Levine, Andrew Stuart, Lena Mamykina, Bruce Gluckman, George Hripcsak, 2018, Journal of the American Medical Informatics Association : JAMIA on p. 1392-1401

A brain–heart biomarker for epileptogenesis

Fatemeh Bahari, Paddy Ssentongo, Steven J. Schiff, Bruce J. Gluckman, 2018, Journal of Neuroscience on p. 8473-8483

The systemdrive: A multisite, multiregion microdrive with independent drive axis angling for chronic multimodal systems neuroscience recordings in freely behaving animals

Myles W. Billard, Fatemeh Bahari, John Kimbugwe, Kevin D. Alloway, Bruce J. Gluckman, 2018, eNeuro

A flexible vanadium oxide thermistor array for localized temperature field measurements in brain

Myles W. Billard, Hitesh A. Basantani, Mark W. Horn, Bruce J. Gluckman, 2016, IEEE Sensors Journal

Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window

Shubham Mirg, Haoyang Chen, Kevin Turner, Kyle Gheres, Jinyun Liu, Bruce J. Gluckman, Patrick Drew, Sri Rajasekhar Kothapalli, 2022, Optics Letters on p. 1121-1124

A Murine Model to Study Epilepsy and SUDEP Induced by Malaria Infection

Paddy Ssentongo, Anna E. Robuccio, Godfrey Thuku, Derek G. Sim, Ali Nabi, Fatemeh Bahari, Balaji Shanmugasundaram, Myles W. Billard, Andrew Geronimo, Kurt W. Short, Patrick J. Drew, Jennifer Baccon, Steven L. Weinstein, Frank G. Gilliam, José A. Stoute, Vernon M. Chinchilli, Andrew F. Read, Bruce J. Gluckman, Steven J. Schiff, 2017, Scientific Reports

Seizure prediction 6: From mechanisms to engineered interventions for epilepsy

Bruce J. Gluckman, Catherine A. Schevon, 2015, Journal of Clinical Neurophysiology on p. 181-187