Ayusman Sen
Distinguished Professor of Chemistry

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440 Chemistry
University Park, PA - axs20@psu.edu
- 814-863-2460
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Micromotors Enzymes Substrates Application Propulsion Catalysis Colloids Convective Flow Fluids Biomass Colloid Light Microfluidics Pumps Drug Delivery Catalase Hydrodynamics Navigation Hydrogen Peroxide Simulation Molecules Catalysts Drug Bacteria Drug Delivery SystemsMost Recent Publications
Light-Powered, Fuel-Free Oscillation, Migration, and Reversible Manipulation of Multiple Cargo Types by Micromotor Swarms
Jianhua Zhang, Abhrajit Laskar, Jiaqi Song, Oleg E. Shklyaev, Fangzhi Mou, Jianguo Guan, Anna C. Balazs, Ayusman Sen, 2023, ACS Nano on p. 251-262
Droplet Navigation by Photothermal Pumping in an Optofluidic System
Jiaqi Song, Jianhua Zhang, Sanjana Krishna Mani, Ayusman Sen, 2022, Langmuir on p. 11486-11491
Corrigendum to Photochemical micromotor of eccentric core in isotropic hollow shell exhibiting multimodal motion behavior [Applied Materials Today 26 (2022) 101371](S2352940722000105)(10.1016/j.apmt.2022.101371)
Jianhua Zhang, Fangzhi Mou, Shaowen Tang, Joshua E. Kauffman, Ayusman Sen, Jianguo Guan, 2022, Applied Materials Today
Response to “Comment on ‘Relative Diffusivities of Bound and Unbound Protein Can Control Chemotactic Directionality’”
Niladri Sekhar Mandal, Ayusman Sen, 2022, Langmuir on p. 2748
Photochemical micromotor of eccentric core in isotropic hollow shell exhibiting multimodal motion behavior
Jianhua Zhang, Fangzhi Mou, Shaowen Tang, Joshua E. Kauffman, Ayusman Sen, Jianguo Guan, 2022, Applied Materials Today
Self-Generated Convective Flows Enhance the Rates of Chemical Reactions
Raj Kumar Manna, Kayla Gentile, Oleg E. Shklyaev, Ayusman Sen, Anna C. Balazs, 2022, Langmuir on p. 1432-1439
Chemical design of self-propelled Janus droplets
Caleb Meredith, Darrell Velegol, Alexander Castonguay, Alexander Castonguay, Yu Chiu, Yu-Jen Chiu, Allan Brooks, Allan Brooks, Pepijn Moerman, Pepijn Moerman, Peter Torab, Pak Kin Wong, Peter Torab, Ayusman Sen, PakKin Wong, Ayusman Sen, Lauren Zarzar, 2022, Matter on p. 616-633
Light-Programmable Assemblies of Isotropic Micromotors
Shengping Che, Jianhua Zhang, Fangzhi Mou, Xia Guo, Joshua E. Kauffman, Ayusman Sen, Jianguo Guan, 2022, Research
Cooperative transport by flocking phototactic micromotors
Jianhua Zhang, Fangzhi Mou, Zhen Wu, Jiaqi Song, Joshua E. Kauffman, Ayusman Sen, Jianguo Guan, 2021, Nanoscale Advances on p. 6157-6163
A simple theory for molecular chemotaxis driven by specific binding interactions
Kathleen T. Krist, Ayusman Sen, W. G. Noid, 2021, Journal of Chemical Physics
Most-Cited Papers
Small power: Autonomous nano- and micromotors propelled by self-generated gradients
Wei Wang, Wentao Duan, Suzanne Ahmed, Thomas E. Mallouk, Ayusman Sen, 2013, Nano Today on p. 531-554
Ortho-phosphinobenzenesulfonate: A superb ligand for palladium-catalyzed coordination-insertion copolymerization of polar vinyl monomers
Akifumi Nakamura, Timo M.J. Anselment, Jerome Claverie, Brian Goodall, Richard F. Jordan, Stefan Mecking, Bernhard Rieger, Ayusman Sen, Piet W.N.M. Van Leeuwen, Kyoko Nozaki, 2013, Accounts of Chemical Research on p. 1438-1449
Intelligent, self-powered, drug delivery systems
Debabrata Patra, Samudra Sengupta, Wentao Duan, Hua Zhang, Ryan Pavlick, Ayusman Sen, 2013, Nanoscale on p. 1273-1283
Boundaries can steer active Janus spheres
Sambeeta Das, Astha Garg, Andrew I. Campbell, Jonathan Howse, Ayusman Sen, Darrell Velegol, Ramin Golestanian, Stephen J. Ebbens, 2015, Nature Communications
Chemical conversion pathways for carbohydrates
Chandrani Chatterjee, Frances Pong, Ayusman Sen, 2015, Green Chemistry on p. 40-71
From one to many: Dynamic assembly and collective behavior of self-propelled colloidal motors
Wei Wang, Wentao Duan, Suzanne Ahmed, Ayusman Sen, Thomas E. Mallouk, 2015, Accounts of Chemical Research on p. 1938-1946
Enzyme molecules as nanomotors
Samudra Sengupta, Krishna K. Dey, Hari S. Muddana, Tristan Tabouillot, Michael E. Ibele, Peter J. Butler, Ayusman Sen, 2013, Journal of the American Chemical Society on p. 1406-1414
Micromotors Powered by Enzyme Catalysis
Krishna K. Dey, Xi Zhao, Benjamin M. Tansi, Wilfredo J. Méndez-Ortiz, Ubaldo M. Córdova-Figueroa, Ramin Golestanian, Ayusman Sen, 2015, Nano Letters on p. 8311-8315
Catalytically powered dynamic assembly of rod-shaped nanomotors and passive tracer particles
Wei Wang, Wentao Duan, Ayusman Sen, Thomas E. Mallouk, 2013, Proceedings of the National Academy of Sciences of the United States of America on p. 17744-17749
'Fuelled' motion: Phoretic motility and collective behaviour of active colloids
Pierre Illien, Ramin Golestanian, Ayusman Sen, 2017, Chemical Society Reviews on p. 5508-5518
News Articles Featuring Ayusman Sen
Dec 05, 2019
Artificial cells act more like the real thing
Protocells -- artificial cells -- that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers.
Full Article
Nov 19, 2019
Directing Self-propelled Protocells To Deliver Drugs
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body. By coating the surface of the protocells with enzymes — proteins that catalyze chemical reactions — a team of researchers at Penn State was able to control the direction of the protocell’s movement in a chemical gradient in a microfluidic device.
Full Article
Nov 18, 2019
Directional control of self-propelled protocells: The future of drug delivery?
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body. By coating the surface of the protocells with enzymes — proteins that catalyze chemical reactions — a team of researchers at Penn State was able to control the direction of the protocell’s movement in a chemical gradient in a microfluidic device.
Full Article
Nov 18, 2019
Directional control of self-propelled protocells
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body.
Full Article
Oct 30, 2019
Tiny swimming donuts deliver the goods
Bacteria and other swimming microorganisms evolved to thrive in challenging environments, and researchers struggle to mimic their unique abilities for biomedical technologies, but fabrication challenges created a manufacturing bottleneck. Microscopic, 3D-printed, tori — donuts — coated with nickel and platinum may bridge the gap between biological and synthetic swimmers, according to an international team of researchers.
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May 28, 2019
Ayusman Sen receives Humboldt Research Award
Ayusman Sen, distinguished professor of chemistry at Penn State, has been awarded a Humboldt Research Award by the Alexander von Humboldt Foundation of Germany.
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