Ayusman Sen
Distinguished Professor of Chemistry
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440 Chemistry
University Park, PA - axs20@psu.edu
- 814-863-2460
Most Recent Publications
Uncovering Chemical Principles Governing Nanophase Formation in Ternary Solvents
Binish Ashfaq, Ayusman Sen, Lauren D. Zarzar, 2025, Angewandte Chemie - International Edition
Ionic gradients in flow to control transport of emissive ions
Lucy L. Fillbrook, Isis A. Middleton, Hamid Rashidnejad, Aditya Sapre, Timothy W. Schmidt, Ayusman Sen, Jonathon E. Beves, 2025, Chemical Communications on p. 3367-3370
Introduction to Active Colloids
Aditya Sapre, Ayusman Sen, Ambarish Ghosh, 2024, on p. 64-95
Programming Fluid Motion Using Multi-Enzyme Micropump Systems
Jiaqi Song, Jianhua Zhang, Jinwei Lin, Oleg E. Shklyaev, Shanid Shrestha, Aditya Sapre, Anna C. Balazs, Ayusman Sen, 2024, ACS applied materials & interfaces on p. 45660-45670
A Cautionary Perspective on Hydrogel-Induced Concentration Gradient Generation for Studying Chemotaxis
Aditya Sapre, Rik Bhattacharyya, Ayusman Sen, 2024, ACS applied materials & interfaces on p. 40131-40138
Chemomechanical Communication between Liposomes Based on Enzyme Cascades
Yu Ching Tseng, Jiaqi Song, Jianhua Zhang, Ekta Shandilya, Ayusman Sen, 2024, Journal of the American Chemical Society on p. 16097-16104
Enzyme Catalysis Causes Fluid Flow, Motility, and Directional Transport on Supported Lipid Bilayers
Aditya Sapre, Niladri Sekhar Mandal, Ambika Somasundar, Ashlesha Bhide, Jiaqi Song, Ali Borhan, Ayusman Sen, 2024, ACS applied materials & interfaces on p. 9380-9387
Self-Propelling Macroscale Sheets Powered by Enzyme Pumps
Jiaqi Song, Oleg E. Shklyaev, Aditya Sapre, Anna C. Balazs, Ayusman Sen, 2024, Angewandte Chemie - International Edition
Dynamic Oscillation and Motion of Oil-in-Water Emulsion Droplets
S Krishna Mani, S Al-Tooqi, J Song, A Sapre, Lauren Zarzar, A Sen, 2024, Angewandte Chemie - International Edition on p. e202316242
Self-Propelling Macroscale Sheets Powered by Enzyme Pumps
J Song, O Shklyaev, A Sapre, A Balazs, Ayusman Sen, 2024, Angew. Chem., Int. Ed.
Most-Cited Papers
Chemical conversion pathways for carbohydrates
Chandrani Chatterjee, Frances Pong, Ayusman Sen, 2015, Green Chemistry on p. 40-71
Boundaries can steer active Janus spheres
Sambeeta Das, Astha Garg, Andrew I. Campbell, Jonathan Howse, Ayusman Sen, Darrell Velegol, Ramin Golestanian, Stephen J. Ebbens, 2015, Nature Communications
From one to many: Dynamic assembly and collective behavior of self-propelled colloidal motors
Wei Wang, Wentao Duan, Suzanne Ahmed, Ayusman Sen, Thomas E. Mallouk, 2015, Accounts of Chemical Research on p. 1938-1946
Micromotors Powered by Enzyme Catalysis
Krishna K. Dey, Xi Zhao, Benjamin M. Tansi, Wilfredo J. Méndez-Ortiz, Ubaldo M. Córdova-Figueroa, Ramin Golestanian, Ayusman Sen, 2015, Nano Letters on p. 8311-8315
'Fuelled' motion: Phoretic motility and collective behaviour of active colloids
Pierre Illien, Ramin Golestanian, Ayusman Sen, 2017, Chemical Society Reviews on p. 5508-5518
Enhanced transport into and out of dead-end pores
Abhishek Kar, Tso Yi Chiang, Isamar Ortiz Rivera, Ayusman Sen, Darrell Velegol, 2015, ACS Nano on p. 746-753
Chemically Propelled Molecules and Machines
Krishna Kanti Dey, Ayusman Sen, 2017, Journal of the American Chemical Society on p. 7666-7676
Positive and negative chemotaxis of enzyme-coated liposome motors
Ambika Somasundar, Subhadip Ghosh, Farzad Mohajeramni, Farzad Mohajerani, Lynnicia N. Massenburg, Tinglu Yang, Paul S. Cremer, Darrell Velegol, Ayusman Sen, 2019, Nature Nanotechnology on p. 1129-1134
Powering Motion with Enzymes
Xi Zhao, Kayla Gentile, Farzad Mohajerani, Ayusman Sen, 2018, Accounts of Chemical Research on p. 2373-2381
Synthetic Nano- and Micromachines in Analytical Chemistry: Sensing, Migration, Capture, Delivery, and Separation
Wentao Duan, Wei Wang, Sambeeta Das, Vinita Yadav, Thomas E. Mallouk, Ayusman Sen, 2015, Annual Review of Analytical Chemistry on p. 311-333
News Articles Featuring Ayusman Sen
Sep 30, 2024
Penn State chemist’s pioneering paper reaches 20-year milestone
The paper that launched the field of self-propelled autonomous nanomotors celebrated at two conferences and featured in award-winning documentary
Full Article
Jun 15, 2023
Penn State researchers use ultrasound to control orientation of small particles
Acoustic waves may be able to control how particles sort themselves. While researchers have been able to separate particles based on their shape — for example, bacteria from other cells — for years, the ability to control their movement has remained a largely unsolved problem, until now.
Full Article
Dec 05, 2019
Artificial cells act more like the real thing
Protocells -- artificial cells -- that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers.
Full Article
Nov 19, 2019
Directing Self-propelled Protocells To Deliver Drugs
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body. By coating the surface of the protocells with enzymes — proteins that catalyze chemical reactions — a team of researchers at Penn State was able to control the direction of the protocell’s movement in a chemical gradient in a microfluidic device.
Full Article
Nov 18, 2019
Directional control of self-propelled protocells: The future of drug delivery?
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body. By coating the surface of the protocells with enzymes — proteins that catalyze chemical reactions — a team of researchers at Penn State was able to control the direction of the protocell’s movement in a chemical gradient in a microfluidic device.
Full Article
Nov 18, 2019
Directional control of self-propelled protocells
Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the body.
Full Article
Oct 30, 2019
Tiny swimming donuts deliver the goods
Bacteria and other swimming microorganisms evolved to thrive in challenging environments, and researchers struggle to mimic their unique abilities for biomedical technologies, but fabrication challenges created a manufacturing bottleneck. Microscopic, 3D-printed, tori — donuts — coated with nickel and platinum may bridge the gap between biological and synthetic swimmers, according to an international team of researchers.
Full Article
May 28, 2019
Ayusman Sen receives Humboldt Research Award
Ayusman Sen, distinguished professor of chemistry at Penn State, has been awarded a Humboldt Research Award by the Alexander von Humboldt Foundation of Germany.
Full Article