Ashley Shay

Director, Metabolomics Core Facility

Ashley Shay

Research Summary

The implementation and expansion of liquid chromatography tandem mass spectrometry for the structural elucidation of novel lipid mediators and metabolites in various inflammatory diseases coupled with diverse cellular and in vivo approaches to determine functionality.

Huck Affiliations

Publication Tags

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Macrophages Regeneration Inflammation Neutrophils Protectin D1 Macrophage Cd59 Antigens Leukocytes Pneumonia Biosynthesis Tandem Mass Spectrometry Leukotriene B4 Interleukin 4 Selenium Fungi Inflammatory Bowel Disease Resolvin D3 Cyclooxygenase 1 Viral Load Nippostrongylus Brasiliensis Resolvin D4 Respiratory Syncytial Virus Infections Selenoprotein Selenoproteins Lung

Most Recent Publications

Lance G.A. Nunes, Chi Ma, Fu Kun W. Hoffmann, Ashley E. Shay, Matthew W. Pitts, Peter R. Hoffmann, 2024, Journal of Biological Chemistry

Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells

Chi Ma, Fukun Hoffmann, Ashley Shay, I Koo, Kathy Green, William Green, Peter Hoffmann, 2024, Journal of Leukocyte Biology

Eosinophil Phenotypes Are Functionally Regulated by Resolvin D2 during Allergic Lung Inflammation

Thayse R. Brüggemann, Hong Yong Peh, Luciana P. Tavares, Julie Nijmeh, Ashley E. Shay, Rafael M. Rezende, Toby B. Lanser, Charles N. Serhan, Bruce D. Levy, 2023, American Journal of Respiratory Cell and Molecular Biology on p. 666-677

Wenjun Li, Hailey M. Shepherd, Yuriko Terada, Ashley E. Shay, Amit I. Bery, Andrew E. Gelman, Kory J. Lavine, Charles N. Serhan, Daniel Kreisel, 2023, Proceedings of the National Academy of Sciences of the United States of America on p. e2302938120

Alex Hopke, Tian Lin, Allison K. Scherer, Ashley E. Shay, Kyle D. Timmer, Brittany Wilson-Mifsud, Michael K. Mansour, Charles N. Serhan, Daniel Irimia, Bryan P. Hurley, 2022, iScience

A. Rakian, R. Rakian, A. E. Shay, C. N. Serhan, T. E. Van Dyke, 2022, Journal of Dental Research on p. 1205-1213

Kajal Hamidzadeh, Jodi Westcott, Nicholas Wourms, Ashley E. Shay, Anand Panigrahy, Michael J. Martin, Robert Nshimiyimana, Charles N. Serhan, 2022, Biochemical Pharmacology

Luciana P. Tavares, Thayse R. Brüggemann, Rafael M. Rezende, Marina G. Machado, R. Elaine Cagnina, Ashley E. Shay, Cristiana C. Garcia, Julie Nijmeh, Mauro M. Teixeira, Bruce D. Levy, 2022, mBio

Ashley E. Shay, Robert Nshimiyimana, Bengt Samuelsson, Nicos A. Petasis, Jesper Z. Haeggstrom, Charles N. Serhan, 2021, Proceedings of the National Academy of Sciences of the United States of America

Katherine H. Walker, Nandini Krishnamoorthy, Thayse R. Brüggemann, Ashley E. Shay, Charles N. Serhan, Bruce D. Levy, 2021, Frontiers in Immunology

Most-Cited Papers

A Kudva, Ashley Shay, K. Sandeep Prabhu, 2015, American Journal of Physiology on p. G71-G77

Stephania Libreros, Ashley E. Shay, Robert Nshimiyimana, David Fichtner, Michael J. Martin, Nicholas Wourms, Charles N. Serhan, 2021, Frontiers in Immunology

S Nelson, Ashley Shay, J James, B Carlson, J Urban, Jr, Joseph F. Urban, K. Sandeep Prabhu, 2016, Journal of Biological Chemistry on p. 2787-2798

Katherine H. Walker, Nandini Krishnamoorthy, Thayse R. Brüggemann, Ashley E. Shay, Charles N. Serhan, Bruce D. Levy, 2021, Frontiers in Immunology

Ashley Shay, B Diwakar, B Guan, V Narayan, Joseph F. Urban, J Urban, Jr, K. Sandeep Prabhu, 2017, Journal of Biological Chemistry on p. 14544-14555

Charlotte C. Jouvene, Ashley E. Shay, Mieke A. Soens, Paul C. Norris, Jesper Z. Haeggström, Charles N. Serhan, 2019, FASEB Journal on p. 13794-13807

Amalie Føreid Reinertsen, Karoline Gangestad Primdahl, Ashley Elizabeth Shay, Charles Nicholas Serhan, Trond Vidar Hansen, Marius Aursnes, 2021, Journal of Organic Chemistry on p. 3535-3545

Ashley E. Shay, Robert Nshimiyimana, Bengt Samuelsson, Nicos A. Petasis, Jesper Z. Haeggstrom, Charles N. Serhan, 2021, Proceedings of the National Academy of Sciences of the United States of America

Alex Hopke, Tian Lin, Allison K. Scherer, Ashley E. Shay, Kyle D. Timmer, Brittany Wilson-Mifsud, Michael K. Mansour, Charles N. Serhan, Daniel Irimia, Bryan P. Hurley, 2022, iScience

Brian E. Sansbury, Xiaofeng Li, Blenda Wong, Colin O. Riley, Ashley E. Shay, Robert Nshimiyimana, Nicos A. Petasis, Charles N. Serhan, Matthew Spite, 2021, American Journal of Pathology on p. 1049-1063