Arun Sharma
Associate Professor of Pharmacology

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Hershey Med Ctr
Hershey, - aks14@psu.edu
- 717-531-8285
Huck Affiliations
Publication Tags
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Neoplasms Therapeutics Apoptosis Selenium Molecule Pharmaceutical Preparations Cells Cell Line Drug Cell Death Colorectal Neoplasms Anti Inflammatory Agents Dna Oligonucleotides Cell Viability Melanoma Derivatives Sulfur Biotin Anti Inflammatory Drug Clostridium Chalcogens Chemistry Antisense Oligonucleotides UreaMost Recent Publications
Seleno-aspirin compound AS-10 promotes histone acetylation ahead of suppressing androgen receptor transcription, G1 arrest, and apoptosis of prostate cancer cells
Deepkamal N. Karelia, Sangyub Kim, Daniel Plano, Arun K. Sharma, Cheng Jiang, Junxuan Lu, 2023, Prostate on p. 16-29
Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: Identification of a Se-indomethacin analog as a potential therapeutic for breast cancer
Sandra Ramos-Inza, Ignacio Encío, Asif Raza, Arun K. Sharma, Carmen Sanmartín, Daniel Plano, 2022, CHIM.THER.
Impact of selenium nanoparticles in the regulation of inflammation
Asif Raza, Hannah Johnson, Amandeep Singh, Arun K. Sharma, 2022, Archives of Biochemistry and Biophysics
Identification and biotin receptor-mediated activity of a novel seleno-biotin compound that inhibits viability of and induces apoptosis in ovarian cancer cells
Asif Raza, Amandeep Singh, Shantu Amin, Julian E. Spallholz, Arun K. Sharma, 2022, Chemico-Biological Interactions
Seleno-Metabolites and Their Precursors: A New Dawn for Several Illnesses?
Cristina Morán-Serradilla, Eduardo Angulo-Elizari, Andreina Henriquez-Figuereo, Carmen Sanmartín, Arun K. Sharma, Daniel Plano, 2022, Metabolites
Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
Satya Narayan, Asif Raza, Iqbal Mahmud, Nayeong Koo, Timothy J. Garrett, Mary E. Law, Brian K. Law, Arun K. Sharma, 2022, iScience
Influence of ceramide on lipid domain stability studied with small-angle neutron scattering: The role of acyl chain length and unsaturation
Mitchell DiPasquale, Tye G. Deering, Dhimant Desai, Arun K. Sharma, Shantu Amin, Todd E. Fox, Mark Kester, John Katsaras, Drew Marquardt, Frederick A. Heberle, 2022, Chemistry and Physics of Lipids
Therapeutics Targeting p53-MDM2 Interaction to Induce Cancer Cell Death
Nayeong Koo, Arun K. Sharma, Satya Narayan, 2022, International Journal of Molecular Sciences
Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides
Amandeep Singh, Asif Raza, Shantu Amin, Chendil Damodaran, Arun K. Sharma, 2022, Molecules
Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells
Nadav Wallis, Froma Oberman, Khriesto Shurrush, Nicolas Germain, Gila Greenwald, Tehila Gershon, Talia Pearl, Giancarlo Abis, Vikash Singh, Amandeep Singh, Arun K. Sharma, Haim M. Barr, Andres Ramos, Vladimir S. Spiegelman, Joel K. Yisraeli, 2022, RNA Biology on p. 26-43
Most-Cited Papers
Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents
Daniel Plano, Deepkamal N. Karelia, Manoj K. Pandey, Julian E. Spallholz, Shantu Amin, Arun K. Sharma, 2016, Journal of Medicinal Chemistry on p. 1946-1959
Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study
James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78
Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors
Daniel Plano, Shantu Amin, Arun Sharma, 2014, Journal of Medicinal Chemistry on p. 5509-5524
Development and Therapeutic Potential of Selenazo Compounds
Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma, Daniel Plano, 2020, Journal of Medicinal Chemistry on p. 1473-1489
Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1- yl)-1-arylethanones: Antibacterial, DNA photocleavage, and anticancer activities
Vinod Kumar, Kamalneet Kaur, Deepkamal N. Karelia, Vikas Beniwal, Girish Kumar Gupta, Arun K. Sharma, Akhilesh Kumar Gupta, 2014, CHIM.THER. on p. 267-276
A Review on Notch Signaling and Colorectal Cancer
Ashish Tyagi, Arun K. Sharma, Chendil Damodaran, 2020, Cells
Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines
Verónica Alcolea, Daniel Plano, Deepkamal N. Karelia, Juan Antonio Palop, Shantu Amin, Carmen Sanmartín, Arun Sharma, 2016, CHIM.THER. on p. 134-144
Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile
John P. Hegarty, Jacek Krzeminski, Arun K. Sharma, Diana Guzman-Villanueva, Volkmar Weissig, David B. Stewart, 2016, International Journal of Nanomedicine on p. 3607-3619
Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells
M Pandey, Krishne Gowda, Kenichiro Doi, Arun Sharma, H Wang, S Amin, 2013, PLoS One on p. e78570
Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity
Verónica Alcolea, Daniel Plano, Ignacio Encío, Juan Antonio Palop, Arun K. Sharma, Carmen Sanmartín, 2016, CHIM.THER. on p. 407-418