Arun Sharma

Associate Professor of Pharmacology

Arun Sharma

Publication Tags

Apoptosis Neoplasms Therapeutics Pharmaceutical Preparations Anti Inflammatory Agents Antineoplastic Agents Cells Fluorouracil Colorectal Neoplasms Quinoxalines Aryl Hydrocarbon Receptors Cell Line Phosphorylation Melanoma Colonic Neoplasms Genes Selenium Transducers Oxaliplatin Death Domain Receptor Signaling Adaptor Proteins Tubulin Modulators Stat3 Transcription Factor Stem Cells Caspase 8 Isatin

Most Recent Papers

Development of Isoselenocyanate Compounds' Syntheses and Biological Applications

Emily E. Frieben, Shantu Amin, Arun Sharma, 2019, Journal of Medicinal Chemistry on p. 5261-5275

Leishmanicidal activity of isoselenocyanate derivatives

Celia Fernández-Rubio, Esther Larrea, José Peña Guerrero, Eduardo Sesma Herrero, Iñigo Gamboa, Carlos Berrio, Daniel Plano, Shantu Amin, Arun K. Sharma, Paul A. Nguewa, 2019, Antimicrobial agents and chemotherapy

Identification of a novel quinoxaline-isoselenourea targeting the STAT3 pathway as a potential melanoma therapeutic

Verónica Alcolea, Deepkamal N. Karelia, Manoj K. Pandey, Daniel Plano, Parvesh Singh, Juan Antonio Palop, Shantu Amin, Carmen Sanmartín, Arun K. Sharma, 2019, International journal of molecular sciences

ASR352, A potent anticancer agent

Satya Narayan, Srinivasa Ramisetti, Aruna S. Jaiswal, Brian K. Law, Ashona Singh-Pillay, Parvesh Singh, Shantu Amin, Arun Sharma, 2019, European Journal of Medicinal Chemistry on p. 456-467

Development and therapeutic potential of selenazo compounds

Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma, Daniel Plano, 2019, Journal of Medicinal Chemistry

The chemopreventive effect of withaferin A on spontaneous and inflammation-associated colon carcinogenesis models

Balaji Chandrasekaran, Deeksha Pal, Venkatesh Kolluru, Ashish Tyagi, Becca Baby, Nisha R. Dahiya, Khafateh Youssef, Houda Alatassi, Murali K. Ankem, Arun K. Sharma, Chendil Damodaran, 2018, Carcinogenesis on p. 1537-1547

Novel selenadiazole derivatives as selective antitumor and radical scavenging agents

Ana Carolina Ruberte, Daniel Plano, Ignacio Encío, Carlos Aydillo, Arun Sharma, Carmen Sanmartín, 2018, European Journal of Medicinal Chemistry on p. 14-27

Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer

Deeksha Pal, Ashish Tyagi, Balaji Chandrasekaran, Houda Alattasi, Murali K. Ankem, Arun K. Sharma, Chendil Damodaran, 2018, Cell Death and Disease

Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells

Wei Wu, Deepkamal Karelia, Kartick Pramanik, Shantu Amin, Arun Sharma, Cheng Jiang, Junxuan Lu, 2018, Molecular Carcinogenesis on p. 1055-1066

Cationic amphiphilic bolaamphiphile-based delivery of antisense oligonucleotides provides a potentially microbiome sparing treatment for C. difficile

Arun Sharma, Jacek Krzeminski, Volkmar Weissig, John P. Hegarty, David B. Stewart, 2018, Journal of Antibiotics on p. 713-721

Most-Cited Papers

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

Megan M. Young, Yoshinori Takahashi, Osman Khan, Sungman Park, Tsukasa Hori, Jong Yun, Arun K. Sharma, Shantu Amin, Chang Deng Hu, Jianke Zhang, Mark Kester, Hong Gang Wang, 2012, Journal of Biological Chemistry on p. 12455-12468

Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties

Iain A. Murray, Gowdahalli Krishnegowda, Brett C. Dinatale, Colin Flaveny, Chris Chiaro, Jyh Ming Lin, Arun K. Sharma, Shantu Amin, Gary H. Perdew, 2010, Chemical research in toxicology on p. 955-966

Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors

Daniel Plano, Shantu Amin, Arun Sharma, 2014, Journal of Medicinal Chemistry on p. 5509-5524

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

Daniel Plano, Deepkamal N. Karelia, Manoj K. Pandey, Julian E. Spallholz, Shantu Amin, Arun K. Sharma, 2016, Journal of Medicinal Chemistry on p. 1946-1959

Characterization of 17-dihydroexemestane glucuronidation

Dongxiao Sun, Gang Chen, Ryan W. Dellinger, Arun K. Sharma, Philip Lazarus, 2010, Pharmacogenetics and Genomics on p. 575-585

Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway

Krishne Gowda, A. S. Prakasha Gowda, Hephzibah Rani S. Tagaram, Kevin F.Staveley O. Carroll, Rosalyn Irby, Arun Sharma, Shantu Amin, 2011, Bioorganic and Medicinal Chemistry on p. 6006-6014

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4

Natalie Nguyen, Arati Sharma, Nhung Nguyen, Arun K. Sharma, Dhimant Desai, Sung Jin Huh, Shantu Amin, Craig Meyers, Gavin P. Robertson, 2011, Cancer Prevention Research on p. 248-258

Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network

Bi Dar Wang, Christina L.B. Kline, Danielle M. Pastor, Thomas L. Olson, Bryan Frank, Truong Luu, Arun K. Sharma, Gavin Robertson, Matthew T. Weirauch, Steven R. Patierno, Joshua M. Stuart, Rosalyn B. Irby, Norman H. Lee, 2010, Molecular Cancer

Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787

Prajakta S. Palkar, Michael G. Borland, Simone Naruhn, Christina H. Ferry, Christina Lee, Ugir H. Sk, Arun Sharma, Shantu Amin, Iain Alexander Murray, Cherie R. Anderson, Gary H. Perdew, Frank J. Gonzalez, Rolf Müller, Jeffrey Maurice Peters, 2010, Molecular pharmacology on p. 419-430

Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′,4′-dimethoxy- α-naphthoflavone

Iain Alexander Murray, Colin A. Flaveny, Christopher R. Chiaro, Arun Sharma, Rachel S. Tanos, Jennifer C. Schroeder, Shantu Amin, William H. Bisson, Siva K. Kolluri, Gary H. Perdew, 2011, Molecular pharmacology on p. 508-519