Arun Sharma
Associate Professor of Pharmacology
-
Hershey Med Ctr
Hershey, - aks14@psu.edu
- 717-531-8285
Huck Affiliations
Publication Tags
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Neoplasms Cells Molecule Drug Cell Line Apoptosis Therapeutics Selenium Pharmaceutical Preparations Melanoma Colorectal Neoplasms Oligonucleotides Dna Antioxidants Cell Viability Derivatives Sulfur Antisense Oligonucleotides Antioxidant Agent Urea Bolaamphiphile Chalcogens Clostridium Molecular Modeling AspirinMost Recent Publications
Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice
Xiaoyang Zhu, Qing Liu, Andrew D. Patterson, Arun K. Sharma, Shantu G. Amin, Samuel M. Cohen, Frank J. Gonzalez, Jeffrey M. Peters, 2023, Metabolites
Dissimilar effects of stereoisomers and racemic hydroxychloroquine on Ca<sup>2+</sup> oscillations in human induced pluripotent stem cell-derived cardiomyocytes
Piotr K. Janicki, Amandeep Singh, Arun K. Sharma, Victor Ruiz-Velasco, 2023, Physiological Reports
Novel Acylselenourea Derivatives: Dual Molecules with Anticancer and Radical Scavenging Activity
Nora Astrain-Redin, Asif Raza, Ignacio Encío, Arun K. Sharma, Daniel Plano, Carmen Sanmartín, 2023, Antioxidants
From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment
Nora Astrain-Redin, Carmen Sanmartin, Arun K. Sharma, Daniel Plano, 2023, Journal of Medicinal Chemistry on p. 3703-3731
Cu-promoted synthesis of Indolo[2,3-b]quinoxaline-Mannich adducts via three-component reaction and their anti-proliferative evaluation on colorectal and ovarian cancer cells
Shefali Chowdhary, Asif Raza, Pule Seboletswe, Nosipho Cele, Arun K. Sharma, Parvesh Singh, Vipan Kumar, 2023, Journal of Molecular Structure
A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth
Uttara Saran, Balaji Chandrasekaran, Ashish Tyagi, Vaibhav Shukla, Amandeep Singh, Arun K. Sharma, Chendil Damodaran, 2023, Frontiers in Pharmacology
Seleno-aspirin compound AS-10 promotes histone acetylation ahead of suppressing androgen receptor transcription, G1 arrest, and apoptosis of prostate cancer cells
Deepkamal Karelia, Sangyub Kim, Daniel Plano, Arun K. Sharma, Cheng Jiang, Junxuan Lu, 2023, Prostate on p. 16--29
Quinoline–1,3,4-Oxadiazole Conjugates: Synthesis, Anticancer Evaluation, and Molecular Modelling Studies
Nosipho Cele, Paul Awolade, Sanjeev Dhawan, Lungisani Khubone, Asif Raza, Arun K. Sharma, Parvesh Singh, 2023, Polycyclic Aromatic Compounds on p. 6437-6457
Seleno-Analogs of Scaffolds Resembling Natural Products a Novel Warhead toward Dual Compounds
Nora Astrain-Redin, Irene Talavera, Esther Moreno, María J. Ramírez, Nuria Martínez-Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano, 2023, Antioxidants
Corrigendum: A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth (Frontiers in Pharmacology, (2023), 14, (1150774), 10.3389/fphar.2023.1150774)
Uttara Saran, Balaji Chandrasekaran, Ashish Tyagi, Vaibhav Shukla, Amandeep Singh, Arun K. Sharma, Chendil Damodaran, 2023, Frontiers in Pharmacology
Most-Cited Papers
Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study
James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78
Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents
Daniel Plano, Deepkamal N. Karelia, Manoj K. Pandey, Julian E. Spallholz, Shantu Amin, Arun K. Sharma, 2016, Journal of Medicinal Chemistry on p. 1946-1959
Development and Therapeutic Potential of Selenazo Compounds
Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma, Daniel Plano, 2020, Journal of Medicinal Chemistry on p. 1473-1489
Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors
Daniel Plano, Shantu Amin, Arun Sharma, 2014, Journal of Medicinal Chemistry on p. 5509-5524
A Review on Notch Signaling and Colorectal Cancer
Ashish Tyagi, Arun K. Sharma, Chendil Damodaran, 2020, Cells
Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1- yl)-1-arylethanones: Antibacterial, DNA photocleavage, and anticancer activities
Vinod Kumar, Kamalneet Kaur, Deepkamal N. Karelia, Vikas Beniwal, Girish Kumar Gupta, Arun K. Sharma, Akhilesh Kumar Gupta, 2014, CHIM.THER. on p. 267-276
Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines
Verónica Alcolea, Daniel Plano, Deepkamal N. Karelia, Juan Antonio Palop, Shantu Amin, Carmen Sanmartín, Arun Sharma, 2016, CHIM.THER. on p. 134-144
Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile
John P. Hegarty, Jacek Krzeminski, Arun K. Sharma, Diana Guzman-Villanueva, Volkmar Weissig, David B. Stewart, 2016, International Journal of Nanomedicine on p. 3607-3619
Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells
M Pandey, Krishne Gowda, Kenichiro Doi, Arun Sharma, H Wang, S Amin, 2013, PLoS One on p. e78570
Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity
Verónica Alcolea, Daniel Plano, Ignacio Encío, Juan Antonio Palop, Arun K. Sharma, Carmen Sanmartín, 2016, CHIM.THER. on p. 407-418