Arun Sharma

Associate Professor of Pharmacology

Arun Sharma

Huck Affiliations

Publication Tags

Cells Pharmaceutical Preparations Apoptosis Neoplasms Therapeutics Selenium Growth Dna Dibenzo(A,L)Pyrene Quinoxalines Solubility Cell Line Melanoma Cyclodextrins Aspirin Proteins Phosphorylation Tubulin Modulators Acids Coal Tar Death Domain Receptor Signaling Adaptor Proteins Environmental Carcinogens Stat3 Transcription Factor Isatin Caspase 8

Most Recent Papers

New formulation of a methylseleno-aspirin analog with anticancer activity towards colon cancer

Ana Carolina Ruberte, Gustavo González-Gaitano, Arun K. Sharma, Carlos Aydillo, Ignacio Encío, Carmen Sanmartín, Daniel Plano, 2020, International Journal of Molecular Sciences on p. 1-17

Synthesis of indole-tethered [1,3,4]thiadiazolo and [1,3,4]oxadiazolo[3,2-a]pyrimidin-5-one hybrids as anti-pancreatic cancer agents

Lalitha Gummidi, Nagaraju Kerru, Paul Awolade, Asif Raza, Arun K. Sharma, Parvesh Singh, 2020, Bioorganic and Medicinal Chemistry Letters

Vilsmeier reagent, NaHSe and diclofenac acid chloride

Ana Carolina Ruberte, Carlos Aydillo, Arun K. Sharma, Carmen Sanmartín, Daniel Plano, 2020, RSC Advances on p. 38404-38408

ASR488, a novel small molecule, activates an mRNA binding protein, CPEB1, and inhibits the growth of bladder cancer

Ashish Tyagi, Venkatesh Kolluru, Balaji Chandrasekaran, Uttara Saran, Arun K. Sharma, Murali K. Ankem, Chendil Damodaran, 2020, Oncology Letters on p. 850-860

The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia

Charyguly Annageldiyev, Su Fern Tan, Shreya Thakur, Pavan Kumar Dhanyamraju, Srinivasa R. Ramisetti, Preeti Bhadauria, Jacob Schick, Zheng Zeng, Varun Sharma, Wendy Dunton, Sinisa Dovat, Dhimant Desai, Hong Zheng, David J. Feith, Thomas P. Loughran, Shantu Amin, Arun K. Sharma, David Claxton, Arati Sharma, 2020, Frontiers in Oncology

Development and Therapeutic Potential of Selenazo Compounds

Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma, Daniel Plano, 2020, Journal of Medicinal Chemistry on p. 1473-1489

An Efficient Synthesis of Dibenzo[a,l]tetracene and Dibenzo[a,j]tetracene and Their Identification in a Coal Tar Extract

Srinivasa R. Ramisetti, Jorge O. Oña-Ruales, Stephen A. Wise, Shantu Amin, Arun K. Sharma, 2020, Polycyclic Aromatic Compounds on p. 88-98

Development of Isoselenocyanate Compounds' Syntheses and Biological Applications

Emily E. Frieben, Shantu Amin, Arun K. Sharma, 2019, Journal of Medicinal Chemistry on p. 5261-5275

Identification of a novel quinoxaline-isoselenourea targeting the STAT3 pathway as a potential melanoma therapeutic

Verónica Alcolea, Deepkamal N. Karelia, Manoj K. Pandey, Daniel Plano, Parvesh Singh, Juan Antonio Palop, Shantu Amin, Carmen Sanmartín, Arun K. Sharma, 2019, International Journal of Molecular Sciences

Leishmanicidal activity of isoselenocyanate derivatives

Celia Fernández-Rubio, Esther Larrea, José Peña Guerrero, Eduardo Sesma Herrero, Iñigo Gamboa, Carlos Berrio, Daniel Plano, Shantu Amin, Arun K. Sharma, Paul A. Nguewa, 2019, Antimicrobial Agents and Chemotherapy

Most-Cited Papers

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

Megan M. Young, Yoshinori Takahashi, Osman Khan, Sungman Park, Tsukasa Hori, Jong Yun, Arun K. Sharma, Shantu Amin, Chang Deng Hu, Jianke Zhang, Mark Kester, Hong Gang Wang, 2012, Journal of Biological Chemistry on p. 12455-12468

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

Daniel Plano, Deepkamal N. Karelia, Manoj K. Pandey, Julian E. Spallholz, Shantu Amin, Arun K. Sharma, 2016, Journal of Medicinal Chemistry on p. 1946-1959

Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors

Daniel Plano, Shantu Amin, Arun Sharma, 2014, Journal of Medicinal Chemistry on p. 5509-5524

Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway

Krishne Gowda, A. S. Prakasha Gowda, Hephzibah Rani S. Tagaram, Kevin F.Staveley O. Carroll, Rosalyn Irby, Arun Sharma, Shantu Amin, 2011, Bioorganic and Medicinal Chemistry on p. 6006-6014

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4

Natalie Nguyen, Arati Sharma, Nhung Nguyen, Arun K. Sharma, Dhimant Desai, Sung Jin Huh, Shantu Amin, Craig Meyers, Gavin P. Robertson, 2011, Cancer Prevention Research on p. 248-258

Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′,4′-dimethoxy- α-naphthoflavone

Iain Alexander Murray, Colin A. Flaveny, Christopher R. Chiaro, Arun Sharma, Rachel S. Tanos, Jennifer C. Schroeder, Shantu Amin, William H. Bisson, Siva K. Kolluri, Gary H. Perdew, 2011, Molecular Pharmacology on p. 508-519

Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1- yl)-1-arylethanones

Vinod Kumar, Kamalneet Kaur, Deepkamal N. Karelia, Vikas Beniwal, Girish Kumar Gupta, Arun K. Sharma, Akhilesh Kumar Gupta, 2014, European Journal of Medicinal Chemistry on p. 267-276

Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity

Joseph B. Guttenplan, Wieslawa Kosinska, Zhong Lin Zhao, Kun Ming Chen, Cesar Aliaga, Joseph Deltondo, Timothy Cooper, Yuan Wan Sun, Shang Min Zhang, Kun Jiang, Richard Bruggeman, Arun K. Sharma, Shantu Amin, Kwangmi Ahn, Karam El-Bayoumy, 2012, International Journal of Cancer on p. 2783-2790

In vitro growth inhibition of human cancer cells by novel honokiol analogs

Jyh ming Lin, A. S. Prakasha Gowda, Arun Sharma, Shantu Amin, 2012, Bioorganic and Medicinal Chemistry on p. 3202-3211

Identification and quantification of DNA adducts in the oral tissues of mice treated with the environmental carcinogen dibenzo[ a,l ]pyrene by HPLC-MS/MS

Shang Min Zhang, Kun Ming Chen, Cesar Aliaga, Yuan Wan Sun, Jyh Ming Lin, Arun K. Sharma, Shantu Amin, Karam El-Bayoumy, 2011, Chemical Research in Toxicology on p. 1297-1303