Arun Sharma

Associate Professor of Pharmacology

Arun Sharma

Huck Affiliations

Publication Tags

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Neoplasms Therapeutics Apoptosis Selenium Molecule Pharmaceutical Preparations Cells Cell Line Drug Cell Death Colorectal Neoplasms Anti Inflammatory Agents Dna Oligonucleotides Cell Viability Melanoma Derivatives Sulfur Biotin Anti Inflammatory Drug Clostridium Chalcogens Chemistry Antisense Oligonucleotides Urea

Most Recent Publications

Seleno-aspirin compound AS-10 promotes histone acetylation ahead of suppressing androgen receptor transcription, G1 arrest, and apoptosis of prostate cancer cells

Deepkamal N. Karelia, Sangyub Kim, Daniel Plano, Arun K. Sharma, Cheng Jiang, Junxuan Lu, 2023, Prostate on p. 16-29

Design, synthesis and anticancer evaluation of novel Se-NSAID hybrid molecules: Identification of a Se-indomethacin analog as a potential therapeutic for breast cancer

Sandra Ramos-Inza, Ignacio Encío, Asif Raza, Arun K. Sharma, Carmen Sanmartín, Daniel Plano, 2022, CHIM.THER.

Impact of selenium nanoparticles in the regulation of inflammation

Asif Raza, Hannah Johnson, Amandeep Singh, Arun K. Sharma, 2022, Archives of Biochemistry and Biophysics

Identification and biotin receptor-mediated activity of a novel seleno-biotin compound that inhibits viability of and induces apoptosis in ovarian cancer cells

Asif Raza, Amandeep Singh, Shantu Amin, Julian E. Spallholz, Arun K. Sharma, 2022, Chemico-Biological Interactions

Seleno-Metabolites and Their Precursors: A New Dawn for Several Illnesses?

Cristina Morán-Serradilla, Eduardo Angulo-Elizari, Andreina Henriquez-Figuereo, Carmen Sanmartín, Arun K. Sharma, Daniel Plano, 2022, Metabolites

Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A

Satya Narayan, Asif Raza, Iqbal Mahmud, Nayeong Koo, Timothy J. Garrett, Mary E. Law, Brian K. Law, Arun K. Sharma, 2022, iScience

Influence of ceramide on lipid domain stability studied with small-angle neutron scattering: The role of acyl chain length and unsaturation

Mitchell DiPasquale, Tye G. Deering, Dhimant Desai, Arun K. Sharma, Shantu Amin, Todd E. Fox, Mark Kester, John Katsaras, Drew Marquardt, Frederick A. Heberle, 2022, Chemistry and Physics of Lipids

Therapeutics Targeting p53-MDM2 Interaction to Induce Cancer Cell Death

Nayeong Koo, Arun K. Sharma, Satya Narayan, 2022, International Journal of Molecular Sciences

Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides

Amandeep Singh, Asif Raza, Shantu Amin, Chendil Damodaran, Arun K. Sharma, 2022, Molecules

Small molecule inhibitor of Igf2bp1 represses Kras and a pro-oncogenic phenotype in cancer cells

Nadav Wallis, Froma Oberman, Khriesto Shurrush, Nicolas Germain, Gila Greenwald, Tehila Gershon, Talia Pearl, Giancarlo Abis, Vikash Singh, Amandeep Singh, Arun K. Sharma, Haim M. Barr, Andres Ramos, Vladimir S. Spiegelman, Joel K. Yisraeli, 2022, RNA Biology on p. 26-43

Most-Cited Papers

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

Daniel Plano, Deepkamal N. Karelia, Manoj K. Pandey, Julian E. Spallholz, Shantu Amin, Arun K. Sharma, 2016, Journal of Medicinal Chemistry on p. 1946-1959

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

James C. Glasbey, Dmitri Nepogodiev, Joana F.F. Simoes, Omar Omar, Elizabeth Li, Mary L. Venn, Mohammad K.Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G. Edwards, Jonathan P. Evans, Marco Fiore, Jose Flavio Videria, Samuel J. Ford, Ian Ganly, Ewen A. Griffiths, Rohan R. Gujjuri, Angelos G. Kolias, Haytham M.A. Kaafarani, Ana Minaya-Bravo, Siobhan C. McKay, Helen M. Mohan, Keith J. Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J. Smart, Grant D. Stewart, Sudha Sundar, Raghavan Vidya, Aneel A. Bhangu, C. Allemand, L. Boccalatte, M. Figari, M. Lamm, J. Larrañaga, C. Marchitelli, F. Noll, D. Odetto, M. Perrotta, J. Saadi, L. Zamora, C. Alurralde, E. L. Caram, D. Eskinazi, J. P. Mendoza, M. Usandivaras, R. Badra, A. Esteban, 2021, Journal of Clinical Oncology on p. 66-78

Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors

Daniel Plano, Shantu Amin, Arun Sharma, 2014, Journal of Medicinal Chemistry on p. 5509-5524

Development and Therapeutic Potential of Selenazo Compounds

Ana Carolina Ruberte, Carmen Sanmartin, Carlos Aydillo, Arun K. Sharma, Daniel Plano, 2020, Journal of Medicinal Chemistry on p. 1473-1489

Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1- yl)-1-arylethanones: Antibacterial, DNA photocleavage, and anticancer activities

Vinod Kumar, Kamalneet Kaur, Deepkamal N. Karelia, Vikas Beniwal, Girish Kumar Gupta, Arun K. Sharma, Akhilesh Kumar Gupta, 2014, CHIM.THER. on p. 267-276

A Review on Notch Signaling and Colorectal Cancer

Ashish Tyagi, Arun K. Sharma, Chendil Damodaran, 2020, Cells

Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines

Verónica Alcolea, Daniel Plano, Deepkamal N. Karelia, Juan Antonio Palop, Shantu Amin, Carmen Sanmartín, Arun Sharma, 2016, CHIM.THER. on p. 134-144

Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile

John P. Hegarty, Jacek Krzeminski, Arun K. Sharma, Diana Guzman-Villanueva, Volkmar Weissig, David B. Stewart, 2016, International Journal of Nanomedicine on p. 3607-3619

Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells

M Pandey, Krishne Gowda, Kenichiro Doi, Arun Sharma, H Wang, S Amin, 2013, PLoS One on p. e78570

Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity

Verónica Alcolea, Daniel Plano, Ignacio Encío, Juan Antonio Palop, Arun K. Sharma, Carmen Sanmartín, 2016, CHIM.THER. on p. 407-418