Aimin Liu

Associate Professor of Biology

Aimin Liu

Research Summary

Biogenesis and function of cilia in mammalian embryonic development.

Huck Affiliations

Links

Publication Tags

Proteins Cilia Hedgehogs Genes Brain Protein Transcription Factors Guide Rna Clustered Regularly Interspaced Short Palindromic Repeats Cell Polarity Drosophila Melanogaster Genome Transfer Rna Cells Ablation Neuroglia Signal Transduction Mice Cell Proliferation Morphogenesis Rna Cluster Analysis Gene Encoding Length Mesoderm

Most Recent Papers

Erratum

Cristin Chon, Grace Chon, Yurika Matsui, Huiqing Zeng, Zhi Chun Lai, Aimin Liu, 2021, PLoS One

Efficient multiplexed genome engineering with a polycistronic tRNA and CRISPR guide-RNA reveals an important role of detonator in reproduction of Drosophila melanogaster

Cristin Chon, Grace Chon, Yurika Matsui, Huiqing Zeng, Zhi Chun Lai, Aimin Liu, 2021, PLoS One

Animal models of human birth defects

Aimin Liu, 2020, on p. 244

Fat4-Dchs1 and planar cell polarity pathways activated by Hedgehog signaling mediate mesenchymal clustering and villification during mammalian intestinal development

Rao-Bhatia, Zhu, Yin, Coquenlorge-Gallon, Zhang, Woo, Sun, Dean, Aimin Liu, Hui, Shivdasani, McNeill, Hopyan, Kim, 2020, Developmental Cell on p. 647-658

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development

Abilasha Rao-Bhatia, Min Zhu, Wen Chi Yin, Sabrina Coquenlorge, Xiaoyun Zhang, Janghee Woo, Yu Sun, Charlotte H. Dean, Aimin Liu, Chi chung Hui, Ramesh A. Shivdasani, Helen McNeill, Sevan Hopyan, Tae Hee Kim, 2020, Developmental Cell on p. 647-658.e6

Preface

Aimin Liu, 2020, Advances in Experimental Medicine and Biology on p. v-vi

Immunohistochemistry and RNA In Situ Hybridization in Mouse Brain Development

Jinling Liu, Aimin Liu, 2020, on p. 475-489

Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

Wei Zhang, Si Lu Yang, Mei Yang, Stephanie Herrlinger, Qiang Shao, John L. Collar, Edgar Fierro, Yanhong Shi, Aimin Liu, Hui Lu, Bruce E. Herring, Ming Lei Guo, Shilpa Buch, Zhen Zhao, Jian Xu, Zhipeng Lu, Jian Fu Chen, 2019, Nature Communications

Proteostasis in the Hedgehog signaling pathway

Aimin Liu, 2019, Seminars in Cell and Developmental Biology on p. 153-163

Distinct activities of Gli1 and Gli2 in the absence of Ift88 and the primary cilia

Yuan Wang, Huiqing Zeng, Aimin Liu, 2019, Journal of Developmental Biology

Most-Cited Papers

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals

Xuan Ye, Huiqing Zeng, Gang Ning, Jeremy F. Reiter, Aimin Liu, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 2164-2169

Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

Wei Zhang, Si Lu Yang, Mei Yang, Stephanie Herrlinger, Qiang Shao, John L. Collar, Edgar Fierro, Yanhong Shi, Aimin Liu, Hui Lu, Bruce E. Herring, Ming Lei Guo, Shilpa Buch, Zhen Zhao, Jian Xu, Zhipeng Lu, Jian Fu Chen, 2019, Nature Communications

Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling

Hongchen Cai, Aimin Liu, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 14751-14756

Centrosomal protein DZIP1 regulates hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis

Chengbing Wang, Wee Chuang Low, Aimin Liu, Baolin Wang, 2013, Journal of Biological Chemistry on p. 29518-29529

Dual function of suppressor of fused in Hh pathway activation and mouse spinal cord patterning

Jinling Liu, Westley Heydeck, Huiqing Zeng, Aimin Liu, 2012, Developmental Biology on p. 141-153

Proteostasis in the Hedgehog signaling pathway

Aimin Liu, 2019, Seminars in Cell and Developmental Biology on p. 153-163

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia

D. Dai, L. Li, A. Huebner, H. Zeng, E. Guevara, D. J. Claypool, A. Liu, J. Chen, 2013, Cell Death and Differentiation on p. 130-138

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development

Abilasha Rao-Bhatia, Min Zhu, Wen Chi Yin, Sabrina Coquenlorge, Xiaoyun Zhang, Janghee Woo, Yu Sun, Charlotte H. Dean, Aimin Liu, Chi chung Hui, Ramesh A. Shivdasani, Helen McNeill, Sevan Hopyan, Tae Hee Kim, 2020, Developmental Cell on p. 647-658.e6

The small GTPase RSG1 controls a final step in primary cilia initiation

Stephanie O. Agbu, Yinwen Liang, Aimin Liu, Kathryn V. Anderson, 2018, Journal of Cell Biology on p. 413-427

The loss of Hh responsiveness by a non-ciliary Gli2 variant

Jinling Liu, Huiqing Zeng, Aimin Liu, 2015, Journal of Embryology and Experimental Morphology on p. 1651-1660