Aimin Liu

Associate Professor of Biology

Aimin Liu

Research Summary

Biogenesis and function of cilia in mammalian embryonic development.

Huck Affiliations

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Publication Tags

These publication tags are generated from the output of this researcher. Click any tag below to view other Huck researchers working on the same topic.

Proteins Genes Cilia Hedgehogs Protein Drosophila Melanogaster Genome Polarity Transfer Rna Cell Polarity Guide Rna Clustered Regularly Interspaced Short Palindromic Repeats Transcription Factors Signal Transduction Morphogenesis Length Stromal Cells Reproduction Cluster Analysis Stat1 Transcription Factor Mesoderm Cells Centrioles Ablation Rna

Most Recent Publications

TMEM132A regulates mouse hindgut morphogenesis and caudal development

Huiqing Zeng, Aimin Liu, 2023, Journal of Embryology and Experimental Morphology

Deficiency of the Planar Cell Polarity Protein Intu Delays Kidney Repair and Suppresses Renal Fibrosis after Acute Kidney Injury

Shixuan Wang, Aimin Liu, Yunchao Su, Zheng Dong, 2023, American Journal of Pathology on p. 275-285

Differential expression of the Tmem132 family genes in the developing mouse nervous system

Yuan Wang, Graham Herzig, Cassandra Molano, Aimin Liu, 2022, Gene Expression Patterns

Hedgehog signaling pathway in development and cancer

Steven Cheng, Matthias Lauth, Aimin Liu, 2022, Frontiers in cell and developmental biology

Editorial: Hedgehog signaling pathway in development and cancer

Steven Y. Cheng, Matthias Lauth, Aimin Liu, 2022, Frontiers in Cell and Developmental Biology

Erratum: Efficient multiplexed genome engineering with a polycistronic tRNA and CRISPR guide-RNA reveals an important role of detonator in reproduction of Drosophila melanogaster (PLoS ONE (2021) 16:1 (e0245454) DOI: 10.1371/journal.pone.0245454)

Cristin Chon, Grace Chon, Yurika Matsui, Huiqing Zeng, Zhi Chun Lai, Aimin Liu, 2021, PLoS One

Efficient multiplexed genome engineering with a polycistronic tRNA and CRISPR guide-RNA reveals an important role of detonator in reproduction of Drosophila melanogaster

Cristin Chon, G Chon, Yurika Matsui, Huiqing Zeng, Zhi Chun Lai, Aimin Liu, 2021, PLoS One on p. e0245454

Animal models of human birth defects

Aimin Liu, 2020, on p. 244

Fat4-Dchs1 and planar cell polarity pathways activated by Hedgehog signaling mediate mesenchymal clustering and villification during mammalian intestinal development

Rao-Bhatia, Zhu, Yin, Coquenlorge-Gallon, Zhang, Woo, Sun, Dean, Aimin Liu, Hui, Shivdasani, McNeill, Hopyan, Kim, 2020, Developmental Cell on p. 647-658

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development

Abilasha Rao-Bhatia, Min Zhu, Wen Chi Yin, Sabrina Coquenlorge, Xiaoyun Zhang, Janghee Woo, Yu Sun, Charlotte H. Dean, Aimin Liu, Chi chung Hui, Ramesh A. Shivdasani, Helen McNeill, Sevan Hopyan, Tae Hee Kim, 2020, Developmental Cell on p. 647-658.e6

Most-Cited Papers

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals

Xuan Ye, Huiqing Zeng, Gang Ning, Jeremy F. Reiter, Aimin Liu, 2014, Proceedings of the National Academy of Sciences of the United States of America on p. 2164-2169

Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

Wei Zhang, Si Lu Yang, Mei Yang, Stephanie Herrlinger, Qiang Shao, John L. Collar, Edgar Fierro, Yanhong Shi, Aimin Liu, Hui Lu, Bruce E. Herring, Ming Lei Guo, Shilpa Buch, Zhen Zhao, Jian Xu, Zhipeng Lu, Jian Fu Chen, 2019, Nature Communications

Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling

Hongchen Cai, Aimin Liu, 2016, Proceedings of the National Academy of Sciences of the United States of America on p. 14751-14756

Centrosomal protein DZIP1 regulates hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis

Chengbing Wang, Wee Chuang Low, Aimin Liu, Baolin Wang, 2013, Journal of Biological Chemistry on p. 29518-29529

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development

Abilasha Rao-Bhatia, Min Zhu, Wen Chi Yin, Sabrina Coquenlorge, Xiaoyun Zhang, Janghee Woo, Yu Sun, Charlotte H. Dean, Aimin Liu, Chi chung Hui, Ramesh A. Shivdasani, Helen McNeill, Sevan Hopyan, Tae Hee Kim, 2020, Developmental Cell on p. 647-658.e6

Proteostasis in the Hedgehog signaling pathway

Aimin Liu, 2019, Seminars in Cell and Developmental Biology on p. 153-163

Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord

Hongchen Cai, Aimin Liu, 2017, Developmental Biology on p. 72-85

The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation

Shixuan Wang, Aimin Liu, Guangyu Wu, Han Fei Ding, Shuang Huang, Stanley Nahman, Zheng Dong, 2018, Nature Communications

The small GTPase RSG1 controls a final step in primary cilia initiation

Stephanie O. Agbu, Yinwen Liang, Aimin Liu, Kathryn V. Anderson, 2018, Journal of Cell Biology on p. 413-427

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia

D. Dai, L. Li, A. Huebner, H. Zeng, E. Guevara, D. J. Claypool, A. Liu, J. Chen, 2013, Cell Death and Differentiation on p. 130-138